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Mechanic and surface properties of central-venous port catheters after removal: A comparison of polyurethane and Silicon rubber materials

  • Central venous port devices made of two different polymeric materials, thermoplastic polyurethane (TPU)and silicone rubber (SiR), were compared due their material properties. Both naïve catheters as well as catheters after removal from patients were investigated. In lab experiments the influence of various chemo-therapeutic solutions on material properties was investigated, where as the samples after removal were compared according to the implanted time inpatient. The macroscopic,mechanical performance was assessed with dynamic, specially adapted tests for elasticity. The degradation status of the materials was determined with common tools of polymer characterisation, such as infrared spectroscopy, molecular weight measurements and various methods of thermal analysis. The surface morphology was an alysed using scanning electron microscopy. A correlation between material properties and clinical performance was proposed. The surface morphology and chemical composition of the polyurethaneCentral venous port devices made of two different polymeric materials, thermoplastic polyurethane (TPU)and silicone rubber (SiR), were compared due their material properties. Both naïve catheters as well as catheters after removal from patients were investigated. In lab experiments the influence of various chemo-therapeutic solutions on material properties was investigated, where as the samples after removal were compared according to the implanted time inpatient. The macroscopic,mechanical performance was assessed with dynamic, specially adapted tests for elasticity. The degradation status of the materials was determined with common tools of polymer characterisation, such as infrared spectroscopy, molecular weight measurements and various methods of thermal analysis. The surface morphology was an alysed using scanning electron microscopy. A correlation between material properties and clinical performance was proposed. The surface morphology and chemical composition of the polyurethane catheter materials can potentially result in increased susceptibility of the catheter to bloodstream infections and thrombotic complications. The higher mechanic failure,especially with increasing implantation time of the silicone catheters is related to the lower mechanical performance compared to the polyurethane material as well as loss of barium sulphate filler particles near the surface of the catheter. This results in preformed microscopic notches, which act as predetermined sites of fracture.zeige mehrzeige weniger

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Metadaten
Autoren/innen:Ulrike Braun, Edelgard Lorenz, Christiane Weimann, Heinz Sturm, I. Karimov, J. Ettl, R. Meier, W. A. Wohlgemuth, H. Berger, M. Wildgruber
Dokumenttyp:Zeitschriftenartikel
Veröffentlichungsform:Verlagsliteratur
Sprache:Englisch
Titel des übergeordneten Werkes (Englisch):Journal of the Mechanical Behavior of Biomedical Materials
Jahr der Erstveröffentlichung:2016
Organisationseinheit der BAM:5 Werkstofftechnik
5 Werkstofftechnik / 5.3 Mechanik der Polymerwerkstoffe
6 Materialschutz und Oberflächentechnik
6 Materialschutz und Oberflächentechnik / 6.0 Abteilungsleitung und andere
Verlag:Elsevier Ltd.
Jahrgang/Band:64
Erste Seite:281
Letzte Seite:291
DDC-Klassifikation:Technik, Medizin, angewandte Wissenschaften / Ingenieurwissenschaften / Ingenieurwissenschaften und zugeordnete Tätigkeiten
Freie Schlagwörter:Catheters; Central venous access port; Complication; Mechanical testing; Silicone rubber (SiR); Structure propertyrelationship; Thermoplastic polyurethane (TPU)
Themenfelder/Aktivitätsfelder der BAM:Material
DOI:https://doi.org/10.1016/j.jmbbm.2016.08.002
URL:http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS&DestLinkType=FullRecord;UT=WOS:000383526100027
ISSN:1751-6161
ISSN:1878-0180
Verfügbarkeit des Volltexts:Volltext-PDF im Netzwerk der BAM verfügbar ("Closed Access")
Datum der Freischaltung:23.08.2016
Referierte Publikation:Ja
Datum der Eintragung als referierte Publikation:13.10.2016