The high diversity of arsenolipids in herring fillet (Clupea harengus)
- Arsenolipids represent a relevant step in the biosynthesis of organoarsenicals from inorganic arsenic compounds. Their fate after human consumption is still uncertain. By means of a HPLC-ICP-MS/ESI-Q-TOF-MS method, 16 lipid soluble arsenic compounds, including seven formerly unknown organoarsenicals, have been identified in commercial herring fillet. The structural assignment was done by exact mass and high resolution MS/MS data. This is the first identification of arsenolipids in herring (Clupea harengus). They contribute with (3.6±0.2) mg kg-1 arsenic to 62.3% of the total arsenic content of (5.7±0.3) mg of arsenic per kg dry mass. Current studies indicate that a metabolization by humans to cancerous dimethylarsinic acid is very likely. The presented results are highly relevant as herring is a very popular food fish species in Europe. Moreover, the screening of different fish species revealed that arsenolipids are more widespread than previously assumed.
Autor*innen: | Susanne Lischka, Uriel Arroyo-Abad, J. Mattusch, Andreas Kühn, Christian Piechotta |
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Dokumenttyp: | Zeitschriftenartikel |
Veröffentlichungsform: | Verlagsliteratur |
Sprache: | Englisch |
Titel des übergeordneten Werkes (Englisch): | Talanta |
Jahr der Erstveröffentlichung: | 2013 |
Verlag: | Elsevier |
Verlagsort: | Amsterdam |
Jahrgang/Band: | 110 |
Erste Seite: | 144 |
Letzte Seite: | 152 |
Freie Schlagwörter: | Arsenic species; Arsenolipids; ESI-MS/MS; Fish; Herring; ICP-TOF-MS |
DOI: | 10.1016/j.talanta.2013.02.051 |
ISSN: | 0039-9140 |
Verfügbarkeit des Dokuments: | Datei im Netzwerk der BAM verfügbar ("Closed Access") |
Datum der Freischaltung: | 20.02.2016 |
Referierte Publikation: | Ja |
Datum der Eintragung als referierte Publikation: | 06.05.2013 |