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Beyond nutrition: host-microbiota interactions drive shifts in the behavioural phenotypes of cockroaches

  • Recent studies have shown that host-microbiota interactions can lead to dramatic changes in host phenotype. We investigate the causal drivers of microbe-associated shifts in host phenotype by examining how feeding behaviour is modulated by microbiota interactions in two omnivorous cockroaches: Blatta orientalis and Blatella germanica. We conducted food-choice experiments after challenging hosts with a common entomopathogenic soil bacterium to understand the impact of pathogens on host macronutrient preference. We find that immune challenge by a pathogenic microbe drives a sharp decline in carbohydrate intake and results in a relative increase in the ratio of protein to carbohydrate (P:C) consumed. Additionally, infected cockroaches reduce their overall nutrient intake, which is consistent with an illness-induced anorexia-like response. We show for the first time that cockroach feeding behaviour is dynamically modulated by a pathogen, and examine the influence of modified feedingRecent studies have shown that host-microbiota interactions can lead to dramatic changes in host phenotype. We investigate the causal drivers of microbe-associated shifts in host phenotype by examining how feeding behaviour is modulated by microbiota interactions in two omnivorous cockroaches: Blatta orientalis and Blatella germanica. We conducted food-choice experiments after challenging hosts with a common entomopathogenic soil bacterium to understand the impact of pathogens on host macronutrient preference. We find that immune challenge by a pathogenic microbe drives a sharp decline in carbohydrate intake and results in a relative increase in the ratio of protein to carbohydrate (P:C) consumed. Additionally, infected cockroaches reduce their overall nutrient intake, which is consistent with an illness-induced anorexia-like response. We show for the first time that cockroach feeding behaviour is dynamically modulated by a pathogen, and examine the influence of modified feeding behaviour on host immunity. We also investigate whether in addition to pathogens, gut commensals are causally responsible for shifts in host behavioural phenotype. Here, we conduct food-choice and immune-challenge experiments in germ-free cockroaches, which have been refaunated with gut microbiota that are experimentally adapted to variable macronutrient (P:C) diets.zeige mehrzeige weniger

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Metadaten
Autoren/innen:Thorben Sieksmeyer
Koautoren/innen:Dino Peter McMahon
Dokumenttyp:Vortrag
Veröffentlichungsform:Präsentation
Sprache:Englisch
Jahr der Erstveröffentlichung:2017
Organisationseinheit der BAM:4 Material und Umwelt
4 Material und Umwelt / 4.0 Abteilungsleitung und andere
DDC-Klassifikation:Technik, Medizin, angewandte Wissenschaften / Ingenieurwissenschaften / Ingenieurwissenschaften und zugeordnete Tätigkeiten
Freie Schlagwörter:Bacterial infection; Cockroach; Gut microbiota; Nutrition
Themenfelder/Aktivitätsfelder der BAM:Material
Material / Life Cycle von Komponenten
Veranstaltung:The 2017 Congress of the European Society for Evolutionary Biology
Veranstaltungsort:Groningen, Netherlands
Beginndatum der Veranstaltung:20.08.2017
Enddatum der Veranstaltung:25.08.2017
Verfügbarkeit des Dokuments:Datei im Netzwerk der BAM verfügbar ("Closed Access")
Datum der Freischaltung:21.02.2018
Referierte Publikation:Nein