Das Suchergebnis hat sich seit Ihrer Suchanfrage verändert. Eventuell werden Dokumente in anderer Reihenfolge angezeigt.
  • Treffer 5 von 73
Zurück zur Trefferliste

OECD Test Guidelines development for chemicals safety assessment of nanomaterials

  • The OECD test guidelines (TGs) for testing chemicals have been widely used for regulatory purposes all over the world since the establishment of the Mutual Acceptance of Data (MAD) principle in 1984. This MAD principle ensures that, if a chemical is tested under the Good Laboratory Practice (GLP) conditions accordingly to an OECD TG, the data should be accepted in all OECD countries. The TGs have been developed, harmonized, internationally validated (round robin tests) and adopted by OECD countries to be used for the physical-chemical characterisation, fate estimation, and hazard identification for risk assessment of various chemicals. In addition to the TGs, OECD Guidance Documents (GDs) usually provide guidance on how to use TGs and how to interpret the results. These GDs do not have to be fully experimentally validated, and hence they are not under MAD, but they are based on relevant published scientific research. But are the existing TGs and the related GDs applicable and adequateThe OECD test guidelines (TGs) for testing chemicals have been widely used for regulatory purposes all over the world since the establishment of the Mutual Acceptance of Data (MAD) principle in 1984. This MAD principle ensures that, if a chemical is tested under the Good Laboratory Practice (GLP) conditions accordingly to an OECD TG, the data should be accepted in all OECD countries. The TGs have been developed, harmonized, internationally validated (round robin tests) and adopted by OECD countries to be used for the physical-chemical characterisation, fate estimation, and hazard identification for risk assessment of various chemicals. In addition to the TGs, OECD Guidance Documents (GDs) usually provide guidance on how to use TGs and how to interpret the results. These GDs do not have to be fully experimentally validated, and hence they are not under MAD, but they are based on relevant published scientific research. But are the existing TGs and the related GDs applicable and adequate for the regulatory testing of nanomaterials? In general, for nanomaterials it is accepted that most of the "endpoints" or more precisely measurement variables are applicable. However, for some endpoints new or amended TGs are needed. In addition, several GDs are needed to give more precise advice on the test performance in order to gain regulatory relevant data on nanomaterials.zeige mehrzeige weniger

Volltext Dateien herunterladen

  • 2019_PTB-Tagungsband_Schwirn.pdf
    eng
  • PTB Tagungsband.pdf
    eng

Metadaten exportieren

Weitere Dienste

Teilen auf Twitter Suche bei Google Scholar Anzahl der Zugriffe auf dieses Dokument
Metadaten
Autor*innen:K. Schwirn, D. Völker, J. Ahtianinen, Alexandra Schmidt, Harald Bresch, K. Kämpf, V. Bachmann, T. Kuhlbusch
Persönliche Herausgeber*innen:H. Bosse, E. Buhr, T. Dziomba, Vasile-Dan Hodoroaba, T. Klein, M. Krumrey
Dokumenttyp:Beitrag zu einem Tagungsband
Veröffentlichungsform:Graue Literatur
Sprache:Englisch
Titel des übergeordneten Werkes (Englisch):PTB-Bericht F-61 - NanoWorkshop 2018: Workshop on Reference Nanomaterials
Jahr der Erstveröffentlichung:2019
Organisationseinheit der BAM:4 Material und Umwelt
4 Material und Umwelt / 4.2 Material-Mikrobiom Wechselwirkungen
Verlag:Physikalisch-Technische Bundesanstalt
Verlagsort:Braunschweig und Berlin
Jahrgang/Band:F-61
Erste Seite:279
Letzte Seite:279
Freie Schlagwörter:Prüfrichtlinie
Guideline; Nano; Nanomaterials; OECD
Themenfelder/Aktivitätsfelder der BAM:Umwelt
Umwelt / Umwelt-Material-Interaktionen
Veranstaltung:NanoWorkshop 2018: Workshop on Reference Nanomaterials
Veranstaltungsort:Berlin, Germany
Beginndatum der Veranstaltung:14.05.2018
Enddatum der Veranstaltung:15.05.2018
DOI:10.7795/110.20190412
ISSN:0179-0609
ISBN:978-3-95606-440-1
Verfügbarkeit des Dokuments:Datei im Netzwerk der BAM verfügbar ("Closed Access")
Datum der Freischaltung:06.11.2019
Referierte Publikation:Nein
Einverstanden
Diese Webseite verwendet technisch erforderliche Session-Cookies. Durch die weitere Nutzung der Webseite stimmen Sie diesem zu. Unsere Datenschutzerklärung finden Sie hier.