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Microfluidic-Assisted Self-Assembly of Dendritic Amphiphiles

  • The controlled production of supramolecular aggregates formed by the self-assembly of dendritic amphiphiles is of great interest owing to their potential application in the fields of nanotechnology and nanomedicine. Dendritic amphiphiles as building blocks offer the advantage that their structure and size can be precisely tuned through organic synthesis. This synthetic flexibility enables the fine-tuning of the hydrophobic to hydrophilic ratio of the dendritic segments, which mainly controls the morphology of the self-assembled structures. A promising method for the controlled preparation of supramolecular assemblies is based on the use of micromixers.[5,6] Due to their mixing times in the range of milliseconds at the microscale level, the application of such microfluidic systems benefits from a high mixing efficiency, a low mixing time and a reproducible synthesis compared to conventional batch-based techniques such as the solvent injection method or the film hydrationThe controlled production of supramolecular aggregates formed by the self-assembly of dendritic amphiphiles is of great interest owing to their potential application in the fields of nanotechnology and nanomedicine. Dendritic amphiphiles as building blocks offer the advantage that their structure and size can be precisely tuned through organic synthesis. This synthetic flexibility enables the fine-tuning of the hydrophobic to hydrophilic ratio of the dendritic segments, which mainly controls the morphology of the self-assembled structures. A promising method for the controlled preparation of supramolecular assemblies is based on the use of micromixers.[5,6] Due to their mixing times in the range of milliseconds at the microscale level, the application of such microfluidic systems benefits from a high mixing efficiency, a low mixing time and a reproducible synthesis compared to conventional batch-based techniques such as the solvent injection method or the film hydration method. Herein, we report on the microfluidic-assisted self-assembly of several dendritic amphiphiles and the impact of the mixing parameters on the self-assembly process.zeige mehrzeige weniger

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Metadaten
Autor*innen:Soraya Taabache
Koautor*innen:Annabelle Bertin, M. Maskos
Dokumenttyp:Posterpräsentation
Veröffentlichungsform:Präsentation
Sprache:Englisch
Jahr der Erstveröffentlichung:2016
DDC-Klassifikation:Technik, Medizin, angewandte Wissenschaften / Ingenieurwissenschaften / Ingenieurwissenschaften und zugeordnete Tätigkeiten
Freie Schlagwörter:Dendrimersomes; Dendritic amphiphiles; Microfluidic; Micromixer; Self-assembly
Veranstaltung:Makromolekulares Kolloquium 2016
Veranstaltungsort:Freiburg im Breisgau, Germany
Beginndatum der Veranstaltung:24.02.2016
Enddatum der Veranstaltung:26.02.2016
Verfügbarkeit des Dokuments:Datei im Netzwerk der BAM verfügbar ("Closed Access")
Datum der Freischaltung:16.03.2016
Referierte Publikation:Nein
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