Quantification of the Alternaria mycotoxin tenuazonic acid in beer
- Tenuazonic acid (TA) is a major water soluble Alternaria mycotoxin. In the present work, a method for the quantification of TA in beer by liquid chromatography-ion-trap multistage mass spectrometry after derivatization with 2,4-dinitrophenylhydrazine is described. The method is based on a rapid workup procedure and features a LOD of 2 µg/kg without preconcentration using 400 mg of sample. Validation was performed for a working range of 8-500 µg/kg. A total of 43 beers of different brewing styles (pilsener, wheat beer, bock beer, dark beer and alcohol free beer) was analysed. TA was detected in 37 samples, 16 samples were above the LOQ. An average content of 11 µg/kg was found, the highest incidence being 175 ± 13 µg/kg. To our knowledge, this is the first report on the occurrence of TA in beer and beverages in general.
Autor*innen: | David Siegel, Stefan Merkel, Matthias KochORCiD, Irene Nehls |
---|---|
Dokumenttyp: | Zeitschriftenartikel |
Veröffentlichungsform: | Verlagsliteratur |
Sprache: | Englisch |
Titel des übergeordneten Werkes (Englisch): | Food chemistry |
Jahr der Erstveröffentlichung: | 2010 |
Verlag: | Elsevier |
Verlagsort: | Amsterdam [u.a.] ; Jena |
Jahrgang/Band: | 120 |
Ausgabe/Heft: | 3 |
Erste Seite: | 902 |
Letzte Seite: | 906 |
Freie Schlagwörter: | 2,4-Dinitrophenylhydrazine; Beer; Derivatization; Liquid chromatography/electrospray ionisation ion-trap multistage mass Spectrome; Mycotoxin; Tenuazonic acid |
DOI: | 10.1016/j.foodchem.2009.10.070 |
ISSN: | 0308-8146 |
Verfügbarkeit des Dokuments: | Physisches Exemplar in der Bibliothek der BAM vorhanden ("Hardcopy Access") |
Bibliotheksstandort: | Sonderstandort: Publica-Schrank |
Datum der Freischaltung: | 19.02.2016 |
Referierte Publikation: | Ja |
Datum der Eintragung als referierte Publikation: | 07.06.2010 |