Stability of ethyl glucuronide in hair reference materials after accelerated aging
- Two different hair reference materials, one produced from authentic hair displaying an ethyl glucuronide (EtG) content of about 25 pg/mg and one obtained by fortification of blank hair to an EtG level of 85 pg/mg were submitted to accelerated aging between 4 degrees C and 60 degrees C for periods between one and 24 months. Subsequently, the EtG content was determined in the aged samples and untreated reference samples stored at -22 degrees C under repeatability conditions following the so-called isochronous approach. The EtG content remained stable even at 40 degrees C for 24 months and at 60 degrees C over six months. This is in contrast to many organic analytes contained in trace concentrations in diverse matrices. A slight but significant increase of the recovered EtG in case of authentic hair samples having been exposed for 24 months between 4 degrees C and 60 degrees C may be due to a temperature-driven process that allows increased recoveries of the physiologically embedded EtG.
Autor*innen: | Dominic Ammann, Roland BeckerORCiD, Irene Nehls |
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Dokumenttyp: | Zeitschriftenartikel |
Veröffentlichungsform: | Verlagsliteratur |
Sprache: | Englisch |
Titel des übergeordneten Werkes (Englisch): | Forensic science international |
Jahr der Erstveröffentlichung: | 2015 |
Verlag: | Elsevier Ireland Ldt. |
Verlagsort: | Amsterdam [u.a.] |
Jahrgang/Band: | 257 |
Erste Seite: | 337 |
Letzte Seite: | 340 |
Freie Schlagwörter: | Alcohol marker; Fortification; HPLC-MS/MS; Long term stability; Micropulverization |
DOI: | 10.1016/j.forsciint.2015.09.015 |
ISSN: | 0379-0738 |
ISSN: | 1872-6283 |
Verfügbarkeit des Dokuments: | Datei im Netzwerk der BAM verfügbar ("Closed Access") |
Datum der Freischaltung: | 20.02.2016 |
Referierte Publikation: | Ja |
Datum der Eintragung als referierte Publikation: | 23.11.2015 |