Effect of disordered structure of boron-containing calcium phosphates on their in vitro biodegradability
- This study proposes a new guideline for designing biodegradable apatite ceramics. Boron-containing hydroxyapatite (BHAp) particles were prepared by a high-temperature solid-state reaction processing method and were characterized in terms of their chemical composition, apatite lattice defects and in vitro biodegradability. Solid-state nuclear magnetic resonance analysis showed that boron-incorporation into hydroxyapatite (HAp) derived by thermo-chemical reactions between borate and calcium phosphate phases led to disordered phases (BCaP) of a CaO–P2O5–B2O3–OH system covering the crystalline HAp core. X-ray diffraction analysis indicated that the BCaP phase must consist mainly of a crystalline oxyboroapatite (OBAp) phase. An in vitro biodegradability test showed that BHAp degraded quicker than HAp or ß-tricalcium phosphate. The biodegradability of BHAp particles can be controlled by boron incorporation into a HAp lattice leading to the formation of a disordered OBAp phase.
Autor*innen: | Sabrina Barheine, S. Hayakawa, Christian Jäger, Y. Shirosaki, A. Osaka |
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Dokumenttyp: | Zeitschriftenartikel |
Veröffentlichungsform: | Verlagsliteratur |
Sprache: | Englisch |
Titel des übergeordneten Werkes (Englisch): | Journal of the American ceramic society |
Jahr der Erstveröffentlichung: | 2011 |
Herausgeber (Institution): | American Ceramic Society |
Verlag: | Blackwell Publishing |
Verlagsort: | Malden |
Jahrgang/Band: | 94 |
Ausgabe/Heft: | 8 |
Erste Seite: | 2656 |
Letzte Seite: | 2662 |
Freie Schlagwörter: | Biodegradability; Boron; Calcium phosphate; Disorder; Hydroxyapatite; NMR; Oxyboboapatite |
DOI: | 10.1111/j.1551-2916.2011.04400.x |
ISSN: | 0002-7820 |
ISSN: | 1551-2916 |
Verfügbarkeit des Dokuments: | Physisches Exemplar in der Bibliothek der BAM vorhanden ("Hardcopy Access") |
Bibliotheksstandort: | Sonderstandort: Publica-Schrank |
Datum der Freischaltung: | 19.02.2016 |
Referierte Publikation: | Ja |
Datum der Eintragung als referierte Publikation: | 06.08.2012 |