TY - CONF A1 - Pauw, Brian Richard A1 - Smales, Glen Jacob A1 - Breßler, Ingo A1 - Hahn, Marc Benjamin T1 - McSAS3: live demo of a Monte Carlo data analyis package for scattering studies N2 - McSAS3 is a refactored software package for fitting large batches of (X-ray or Neutron) scattering data. It uses a Monte-Carlo acceptance-rejection algorithm to optimize model parameters - ideal for analysis of size-disperse scatterers. The refactored code can exploit multiprocessing, traceably stores (multiple) results in the output file, and allows for re-histogramming of previous optimizations. Besides analysis of large batches, it can also be integrated in automated data processing pipelines. The live demonstration will show how to use the software, what its limitations are, and what outcomes can look like for batches of results. T2 - SAS Analysis Course 2023 CY - Didcot, UK DA - 05.06.2023 KW - Scattering KW - Software KW - Analysis KW - Demonstration KW - McSAS3 KW - MOUSE KW - Monte Carlo KW - Automated analysis PY - 2023 AN - OPUS4-57630 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Sachse, René A1 - Pflüger, Mika A1 - Velasco-Vélez, Juan-Jesús A1 - Sahre, Mario A1 - Radnik, Jörg A1 - Bernicke, Michael A1 - Bernsmeier, Denis A1 - Hodoroaba, Vasile-Dan A1 - Krumrey, Michael A1 - Strasser, Peter A1 - Hertwig, Andreas A1 - Kraehnert, Ralph T1 - Operando electrochemical spectroscopic ellipsometry: Material properties of highly active mesoporous IrO IrOxfilms revealed under realistic OER conditions N2 - Rising energy demand and the impending climate change require the development of a sustainable, fossil-free fuel and chemical production on a global scale. Hydrogen production via water electrolysis will be a fundamental cornerstone in this endeavor. The activity and stability of respective electrode coatings strongly depends on the coating's properties, i.e. phase composition, crystallinity, electrical conductivity, accessible surface, wettability and many other factors. The key to the development of improved catalysts is a better understanding of the relations between their performance, stability and physicochemical properties. However, those relations can be complex, and are strongly influenced also by the reaction environment. Hence, operando analysis of the catalyst material during catalysis at realistic potentials and current densities is highly desirable. Yet, many analytical techniques cannot be applied in liquid environments at realistic potentials and current densities. We propose environmental ellipsometric analysis in a dedicated electrochemical flow cell as a new method to evaluate gas evolution reactions operando under realistic working conditions. Figure 1 illustrates schematically the developed technique. Key factors to success are highly active model-type catalysts with template-controlled porosity, a suitable sample environment, a deep understanding of the spectroscopic method and respective model development, as well as concise cross validation with numerous other analytical techniques. The method was developed and validated by analyzing a calcination series (300 - 600°C) of mesoporous templated IrOx films ex-situ and operando under oxygen evolution reaction (OER) conditions. The employed environmental electrochemical spectroscopic ellipsometric analysis (ECSE) revealed during OER the change of optical and electronic properties, i.e. the dielectric functions (real ε1 and imaginary part ε2), electrical and electronic properties such as resistivity (ρ) and band-to-band transitions (p-d band transitions). Film thickness and porosity were validated by means of scanning electron microscopy (SEM), X-ray reflectometry (XRR) or ellipsometric porosimetry (EP), electrical and electronic properties by means of conductivity measurements, X-ray photoelectron spectroscopy (XPS) or UV-Vis-NIR absorption spectroscopy. The electronic structures of the catalysts from valence electron energy loss spectra (VEELS) derived from the real (ε1) and imaginary part (ε2) of the dielectric function from SE measurements reveal a direct correlation with electrochemical activities in OER. In the presentation reversible and irreversible potential-dependent changes of the catalyst properties during operation will be discussed along with the dynamics of gas formation, transport and dissolution at different potentials. T2 - 54. Jahrestreffen deutscher Katalytiker CY - Online meeting DA - 16.03.2021 KW - Spectroscopic ellipsometry KW - Electrocatalysis KW - Oxygen evolution reaction KW - Mesoporous iridium oxide films KW - Non-destructive operando analysis PY - 2021 AN - OPUS4-52928 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Radnik, Jörg T1 - Colours, nano and surface N2 - The basic ideas of colours and pigments are presented. The correlation between nanomaterials and colours are explained. Different methods are presented for investigating nanoparticles and their surface. At the end a case study is presented explaining the importance of coating for the properties of nanoparticles. T2 - Eingeladener Vortrag im Deutschen Lackmuseum (Münster) CY - Online meeting DA - 11.02.2022 KW - Pigments KW - Surface Analytics KW - Coatings PY - 2022 AN - OPUS4-54376 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin T1 - Radiation biophysics N2 - We give an overview about our work related to radiation damage to DNA, proteins, and DNA-protiren complexes damage. Hereby the focus lies on the combination of experiments and Geant4 particle scattering simulations to understand effects in plasmid DNA pUC19, Oligos, and G5P protein. T2 - Project overview CY - Berlin, Germany DA - 27.09.2023 KW - DNA KW - Dosimetry KW - Proteins KW - Radiation damage KW - G5P KW - Microdosimetry KW - Ionizing radiation KW - Geant4 KW - TOPAS KW - TOPAS-nBio KW - Geant4-DNA KW - LEE KW - OH KW - Hydroxyl radical PY - 2023 AN - OPUS4-58742 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Sachse, René A1 - Pflüger, Mika A1 - Velasco Vélez, Juan Jesús A1 - Sahre, Mario A1 - Radnik, Jörg A1 - Bernicke, Michael A1 - Bernsmeier, Denis A1 - Hodoroaba, Vasile-Dan A1 - Krumrey, Michael A1 - Strasser, Peter A1 - Kraehnert, Ralph A1 - Hertwig, Andreas T1 - Operando electrochemical spectroscopic ellipsometry: Material properties of highly active mesoporous IrO IrOxfilms revealed under realistic OER conditions N2 - In the face of rising energy demand and the impending climate change the development of a sustainable, fossil-free fuel and chemical production is of global importance. One possible goal is the development of electrochemical conversion processes using catalysts. Porous materials play an important role in such energy applications. The activity and stability of each catalyst is highly dependent on the properties of the coating, i.e., phase composition, crystallinity, accessible surface area, and many other factors. The key to the development of improved catalysts is a better understanding of the relations between their performance, stability and physico-chemical properties. However, the complex morphology of such catalysts constitutes a challenge even for modern analytical techniques. Spectroscopic ellipsometry (SE) is a versatile method for studying material properties by using appropriate models (e.g., film thickness, optical and electronic properties). Ellipsometric models need to be validated in order to produce accurate results. In a first step, the model for the ellipsometric fit studies of a calcination series of mesoporous iridium oxide films (300 – 600 °C) was investigated and validated with respect to their material properties.[4] The information on electronic structure of the catalysts shows a direct correlation with electrochemical activities. The development of an environmental electrochemical cell offers the possibility of investigations under operando conditions. Thus, changes in optical and electronic properties can be induced and monitored during the electrocatalytic oxygen evolution reaction. T2 - 9th International Conference on Spectroscopic Ellipsometry CY - Beijing, China DA - 22.05.2022 KW - Mesoporous iridium oxide films KW - Non-destructive operando analysis KW - Oxygen evolution reaction KW - Spectroscopic ellipsometry PY - 2022 AN - OPUS4-54915 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Radnik, Jörg T1 - Xps/Haxpes at (core shell) nanoparticles N2 - The principles of (Hard) X-ray photoelectron spectroscopy and some application in the field of (core-shell) nanoparticles will be presented. The presentation should answer hoe to get reliable results. Furthermore, examples of the correlation between physical-chemical measurments and toxicological results are given which are crucial for the risk assessment of nanoparticles. T2 - Training Course Metrological Determination of Micro and Nano Contaminants in Food CY - Berne, Switzerland DA - 05.09.2023 KW - X-ray photoelectron spectroscopy KW - Core-shell nanoparticles KW - Reliabiilty KW - Risk assessment PY - 2023 AN - OPUS4-59496 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin A1 - Dietrich, P. M. A1 - Radnik, Jörg A1 - Solomun, Tihomir A1 - Hallier, Dorothea C. A1 - Seitz, H. T1 - The change of dna and protein radiation damage upon hydration: in-situ observations by near-ambient-pressure xps N2 - X-ray photoelectron-spectroscopy (XPS) allows simultaneous irradiation and damage monitoring. Although water radiolysis is essential for radiation damage, all previous XPS studies were performed in vacuum. Here we present near-ambient-pressure XPS experiments to directly measure DNA damage under water atmosphere. They permit in-situ monitoring of the effects of radicals on fully hydrated double-stranded DNA. Our results allow us to distinguish direct damage, by photons and secondary low-energy electrons (LEE), from damage by hydroxyl radicals or hydration induced modifications of damage pathways. The exposure of dry DNA to x-rays leads to strand-breaks at the sugar-phosphate backbone, while deoxyribose and nucleobases are less affected. In contrast, a strong increase of DNA damage is observed in water, where OH-radicals are produced. In consequence, base damage and base release become predominant, even though the number of strand-breaks increases further. Furthermore, first data about the degradation of single-stranded DNA binding-proteins (G5P / GV5 and hmtSSB) under vacuum and NAP-XPS conditions are presented. T2 - AVS69 CY - Portland, USA DA - 05.11.2023 KW - Base damage KW - Base loss KW - Cancer treatment KW - DNA KW - Protein KW - Proteins KW - Geant4 KW - Dosimetry KW - Microdosimetry KW - NAP-XPS KW - Xray photo electron spectrocopy KW - Radiation damage KW - Geant4-DNA KW - G5P KW - GVP KW - Hydroxyl radical KW - LEE KW - DEA KW - DET KW - ROS KW - Prehydrated electron KW - TOPAS KW - Near ambient pressure xray photo electron spectroscopy KW - SSB KW - DSB KW - Single-strand break (SSB) KW - ESCA KW - Single-stranded DNA-binding proteins KW - Reactive oxygen species PY - 2023 AN - OPUS4-58761 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Radnik, Jörg T1 - How to measure the chemical composition of industrial graphene - New insights from an interlaboratory comparison N2 - International standards describing reliable protocols will facilitate the commercialization of graphene and related 2D materials. One physico-chemical key property next to flake size and thickness is the chemical composition of the material. Therefore, an ISO standard is under development with X-ray photoelectron spectroscopy having a prominent role. With its information depth of around 10 nm which is the similar length scale as the thickness as of particles of 2D materials consisting of a few monolayer XPS seems to be highly suitable for this purpose. Different sample preparation methods like pressing the powders onto adhesive tapes, into recesses, or into solid pellets result in inconsistencies in the quantification. For the validation of the quantification with XPS an interlaboratory comparison was initiated under the auspice of the “Versailles Project on Advanced Materials and Standards” (VAMAS). First results confirm that the sample preparation method (pellet vs. powder) influences the quantification results clearly. T2 - Characterization of Nanomaterials Colloquium CY - Berlin, Germany DA - 04.07.2023 KW - X-ray photoelectron spectroscopy KW - Functionalized graphene KW - Interlaboratory comparison PY - 2023 AN - OPUS4-57897 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin T1 - Radiation biophysics: a journey N2 - We give an overview about recent work concerning ionizing radiation damage to Oligonucleotides, plasmid DNA, DNA binding proteins (G5P), and DNA-protein complexes. We focus on combining new experimental setups with Geant4/TOPAS particle scattering simulations to understand the effets of ionizing radiation. T2 - Project update CY - Online meeting DA - 09.10.2023 KW - DNA KW - Proteins KW - G5P KW - Geant4 KW - Geant4-DNA KW - TOPAS KW - TOPAS-nBio KW - LEE KW - Dosimetry KW - Microdosimetry KW - Magnetism KW - Protein PY - 2023 AN - OPUS4-58744 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Müller, Anja A1 - Radnik, Jörg A1 - Lippitz, Andreas A1 - Unger, Wolfgang T1 - Progress Talk 3 / Non-destructive depth profiling of core-shell nanoparticles by ER-XPS N2 - This presentation deals with the progress between month twenty and twenty-nine of my PhD thesis. I prepared it, in order to update my supervisor Prof. Kemnitz and my colleagues from the department of chemistry at the Humboldt-Universität zu Berlin (HU). T2 - Working Group Meeting of Prof. Erhard Kemnitz CY - Humboldt-Universität zu Berlin (HU), Germany DA - 20.11.2018 KW - ER-XPS KW - Synchrotron KW - Core-shell nanoparticles KW - Depth-profiling PY - 2018 AN - OPUS4-46676 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Riedel, Soraya A1 - Hülagü, Deniz A1 - Bennet, Francesca A1 - Carl, Peter A1 - Flemig, Sabine A1 - Schmid, Thomas A1 - Schenk, Jörg A1 - Hodoroaba, Vasile-Dan A1 - Schneider, Rudolf T1 - Application of 3,3’,5,5’-Tetramethylbenzidine (TMB) in Amperometric Immunoassays for Mycotoxin Detection N2 - Electrochemical methods make great promise to meet the demand for user-friendly on-site devices for monitoring important parameters. Food industry often runs own lab procedures, e.g., for mycotoxin analysis, but it is a major goal to simplify analysis, linking analytical methods with miniaturized technologies. Enzyme-linked immunosorbent assays, with photometric detection of the horseradish peroxidase (HRP) substrate 3,3’,5,5’-tetramethylbenzidine (TMB), form a good basis for sensitive detection. To provide a straight-forward approach for the miniaturization of the detection step, we have studied the pitfalls of the electrochemical TMB detection. By cyclic voltammetry, it could be shown that TMB electrochemistry is strongly dependent on the pH and the electrode material. It was found that screen-printed gold electrodes and a very low pH value (pH 1) are well-suited to perform the electrochemical detection of TMB, due to the reversible character of the redox reaction under these conditions. Under these conditions, a good signal stability over several measuring cycles is achieved, providing the basis for analyzing multiple samples. In contrast to this, for carbon screen-printed electrodes, it was found that the signal response has changed after the electrochemical reaction with TMB at pH 1. At moderately acidic conditions (pH 4), neither with carbon nor with gold electrodes a reproducible electrochemical detection of TMB could be achieved. Based on these findings, we created a smartphone-based, electrochemical, immunomagnetic assay for the detection of ochratoxin A (OTA) and ergometrine in food samples. A competitive assay is performed on magnetic beads using HRP and TMB/H2O2 to generate the signal. Enzymatically oxidized TMB is quantified after addition of H2SO4 by amperometry with screen-printed gold electrodes in a custom-made wall-jet flow cell. The results are in good correlation with the established photometric detection method, providing a solid basis for sensing of further analytes in HRP-based assays using the newly developed miniaturized smartphone-based, electrochemical, immunomagnetic assay. T2 - 73rd Annual Meeting of the ISE CY - Online meeting DA - 12.09.2022 KW - Cylic Voltammetry KW - Immunoassay KW - Mycotoxins KW - Amperometry KW - Electrochemistry PY - 2022 N1 - Geburtsname von Riedel, Soraya: Höfs, S. - Birth name of Riedel, Soraya: Höfs, S. AN - OPUS4-55793 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Chapartegui, Ander A1 - Emmerling, Franziska A1 - Schneider, Rudolf T1 - Metal-Organic Frameworks as turn on fluorescent optical sensors against endocrine disrupting phthalate plasticizers N2 - The development of quick and simple optical sensing technologies for Endocrine Disrupting Chemicals (EDCs) is needed to facilitate monitoring of these substances to ensure consumer safety. Optical sensing was achieved against phthalates acting as EDC that have host guest interaction with an intercalated Metal-organic framework (MOF), resulting in a fluorescence emission upon excitation. The fluorescent turn-on signal was generated by using a fluorophore with a structural component that has little fluorescence unless excimers are formed. Strategies to engineer functional MOF structures suitable for sensing EDC phthalates were developed, and the characterization of the MOFs with and without present phthalates was done by single crystal XRD, PXRD, RAMAN and Thermogravimetry. Extensive photo-physical characterization of host-guest complexes of different phthalates and the MOF as well as the resulting exciplex fluorescence was performed. Photo physical characterization revealed an analyte specific fluorescence fingerprint that allows discerning even minute changes in chemical structures of the analyte and therefore paving the way for sensing tools in real world analytical applications. The presented capability of MOFs to sense EDCs is envisioned to complement established methods from analytical chemistry such as mass spectrometry based methods which can’t be used on site and are often associated with infrastructural capacity constraints T2 - EURoptrode CY - Naples, Italy DA - 25.03.2018 KW - MOF KW - Short chained Phthalates PY - 2018 AN - OPUS4-46890 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Radnik, Jörg T1 - XPS at BAM - Some insights into our activities N2 - Some examples will be given showing the application of XPS in different fields, like polymers, nanoparticles, solar cells and inorganic thin films. T2 - Besuch beim GFZ Potsdam CY - Potsdam, Germany DA - 18.05.2018 KW - XPS KW - Surface analytics KW - Nanoparticles KW - Polymers KW - Solar cells PY - 2018 AN - OPUS4-44981 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Radnik, Jörg A1 - Müller, Anja T1 - Introduction to photoelectronspectroscopy N2 - A short introduction to XPS/ESCA with the focus on nanoparticles and the preparation of such particles for the measurements T2 - Meeting of ACE Nano CY - Berlin, Germany DA - 18.02.2019 KW - ESCA/XPS KW - Nanoparticles KW - Preparation PY - 2019 AN - OPUS4-47437 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin T1 - Geant4: A universal Monte-Carlo toolkit for Particle scattering simulations N2 - Particle scattering simulations are an useful tool to plan experiments, design detectors, estimate doses in irradiated materials and medical treatment planning. Geant4 is a Monte-Carlo toolkit for the simulation of of particles scattering in matter. Photons, electrons, ions etc can be simulated with energies in the eV to GeV range. Their interactions with matter in arbitrary scattering geometries be studied. Scattering models, cross sections and material parameters can be set to cover interactions in gas, liquid and solid state. The import of geometries from computer aided design files or the protein data base is possible. It is currently being applied in high energy and nuclear physics, accelerator and detector design, space application, dosimetry and medical sciences. In this first part of the talk a brief overview over the structure, functionality and possible applications of Geant4 will be given. In the second part an example application will be presented: The determination of the microscopic dose-damage relations in aqueous environment for electron irradiated plasmid DNA will be explained. Therefore, we combine electron scattering simulations in water with calculations concerning the movement of biomolecules to obtain the energy deposit in the biologically relevant nanoscopic volume. We present, how to combine these simulational results and experimental data via a generalized damage model to determine the microscopic dose-damage relation at a molecular level. T2 - Department 6 Seminar CY - Berlin, Germany DA - 04.04.2019 KW - Geant4 KW - Dosimetry KW - Microdosimetry KW - Radiation damage KW - Electron irradiation KW - Monte-Carlo Simulation KW - Monte-Carlo Simulations KW - DNA KW - Computer simulation KW - Geant4-DNA PY - 2019 AN - OPUS4-47819 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Sturm, Heinz A1 - Altmann, Korinna A1 - Braun, Ulrike T1 - Notwendigkeit von (Realistischen) Referenzmaterialien N2 - Die Herstellung von Mikroplastik Referenzmaterialien wird vorgestellt. T2 - Statusfonferenz der BMBF Fördermassnahme "Plastik in der Umwelt" CY - Berlin, Germany DA - 09.04.2019 KW - Ringversuch KW - Mikroplastik KW - Referenzmaterialien PY - 2019 AN - OPUS4-47798 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin T1 - DNA based Reference Materials: In Biodosimetry and Pharmaceutical Quality Control N2 - Applications of plasmid DNA base reference materials in dosimetry and pharmaceutical research. T2 - Physical and Chemical Analysis of Polymers seminar CY - Online meeting DA - 29.03.2021 KW - Analytic KW - Certification KW - DNA KW - Dosimetry KW - Homogeneity KW - Quality testing KW - Reference material KW - Referenzmaterialien KW - Stability KW - Dose KW - Radiation KW - Pharmacy KW - Electrohpresis PY - 2021 AN - OPUS4-52361 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin T1 - Reference Materials at BAM N2 - A introduction into reference materials, the certification process and brief over current reference projects at BAM is given. T2 - AK-Postdoc seminar CY - BAM Berlin, Germany DA - 02.02.2021 KW - Referenzmaterialien KW - Reference material KW - Homogeneity KW - Stability KW - Quality testing KW - Analytic KW - DNA KW - Dosimetry KW - Certification PY - 2021 AN - OPUS4-52060 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin T1 - Data processing and nonlinear curve Fitting with fityk N2 - A brief introduction into fityk is given. The introduction is followed by a pratical session. Fityk is a versatile data processing tool for nonlinear curve fitting. T2 - AFM Data analysis seminar CY - Online meeting DA - 23.02.2021 KW - Fityk KW - Curve fitting KW - Analysis KW - Raman KW - IR KW - XPS PY - 2021 AN - OPUS4-52154 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Radnik, Jörg A1 - Kunz, Valentin A1 - Schneider, Markus A1 - Nymark, Penny A1 - Grafström, Roland A1 - Unger, Wolfgang T1 - Combining surface analytic and toxicity data for safer nanomaterials N2 - Nanomaterials are present in our everyday life. Paint coats, sunscreens, catalysts and additives for tyres are good examples for the use of such materials in mass-market products. The problem of the safety of nanomaterials is recognized as a problem for health and environment, which lead to the special registration of nanomaterials according to an annex of REACH as of 2020. But a great problem for the risk assessment of nanomaterials that several factors could influence the hazardous nature of them. Additional to composition, crystal structure, size and shape the surface properties of such particles belong to these parameters for risk assesment. The reason for the relevance of the surface is obvious: the smaller the particle, the higher is the share of the surface. Additionally, the surface is the region of the particle which interacts with the surrounding which is another crucial factor for the understanding the effect of a nanomaterial on health and environment. In the OECD Testing Programme on Manufactured Nanomaterials exists consequently an Endpoint 4.30 Surface Chemistry in Chapter 4. PHYSICAL AND CHEMICAL PROPERTIES. In summary, there is obviously a need for a correlation between surface chemical analytic data and toxicity. To fill in this gap, we present surface analytic results obtained with X-ray photoelectron spectroscopy and Time-of-Flight Secondary Ion Mass Spectrometry and correlate them with cytotoxic data gain by high-throughput screening experiments. It must be noted, that these experiments were done at the same set of titania materials taken from the JRC (Joint Research Centre of the European Union) Nanomaterials Repository. As material TiO2 was chosen due to its widespread use in consumer products, e.g. paint coats and sunscreens. With this new approach a better understanding of the influence of surface properties on the toxicity can be expected leading to a better risk assessment of these materials. T2 - ECASIA 2019 CY - Dresden, Germany DA - 15.09.2019 KW - Risk assessment KW - Nanomaterials KW - Surface analytic KW - Toxicology PY - 2019 AN - OPUS4-49090 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -