TY - CONF A1 - Radnik, Jörg T1 - The next steps in the standardisation of graphene-related and other 2D materials (GR2M) N2 - The first products with graphene-related 2D material (GR2M) are on the market. In this phase trust is essential for the commercial success of these products, between the individual partners of the product value chain, and between the manufacturer and the consumer. Standards are an important tool for building this trust. The first steps have been taken in standardisation, e.g. in terminology and the characterization of raw materials. But there are still some challenges to overcome such as bringing the standards to the factory floor and real-world products. For the validation of new protocols and methods there is a need of reference data and materials. But not only the measurement should be reproducible, the whole analytical workflow from sample storage and preparation to data analysis should be reproducible. Another important issue is the establishment of credible structure-activity relationships which allows the prediction of the properties of the GR2M, but also of the biological activity including the safety for the human health and the environment. Such relationships can be used for read-across and grouping and can facilitate the regulation of the advanced materials. In addition, 2D materials beyond graphene should also be considered and can benefit from the experience from the standardisation of graphene and graphene oxide. T2 - Nanomaterials Standardization Strategy Forum - Europe - Republic of Korea CY - Online meeting DA - 08.07.2025 KW - Commercialisation KW - Product-value chain KW - Confidence building PY - 2025 AN - OPUS4-63731 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Mrkwitschka, Paul T1 - Standardized Chemical Composition Analysis of Graphene Oxide Flakes with SEM/EDS and XPS Works Reliably N2 - Reliable quantification of the chemical composition of graphene-related 2D materials as powders and liquid suspensions is a challenging task. Analytical methods such as XPS, ICP-MS, TGA and FTIR are recommended to be used in ongoing projects at standardization bodies. The specific parameters to be measured are also defined, e.g. the oxygen-to-carbon (O/C) concentration ratio, the trace metal impurities, or the functional groups present [1]. In this contribution, for the first time, the results of a systematic study on the capability of SEM/EDS to reliably quantify the O/C ratio in a well-defined and well-characterized graphene oxide material [2] are presented. It is expected that the quantitative EDS analysis of light elements emitting characteristic X-ray lines below 1 keV to be provided with significantly larger measurement uncertainties than the analysis of elements with an atomic number of 11 (Na) or above [3]. The robustness of the SEM/EDS results obtained at various measurement conditions (various excitation energies) is tested by comparing the results to the established XPS analysis [4], which has been carried out on the same samples. A crucial step in sample preparation from liquid suspension with graphene oxides flakes onto a substrate for analysis with both XPS and EDS. It is demonstrated that if a closed and enough thick drop-cast deposited spot is succeeded to be deposited on a substrate, both surface-sensitive XPS analysis and bulk-characterizing EDS result in very similar elemental composition of oxygen and carbon. Hence, theoretical, expected O/C atomic ratio values for pure graphene oxide of ~0.5 [1] are achieved (with both methods), see Figure 1. Further, the effect of untight deposited material enabling co-analysis of the (silicon) substrate, is evaluated for both methods, XPS and EDS. To note that all the EDS results in this study have been quantified standardless. The effect of the variation of beam voltage on the result of the quantification of the O/C ratio is shown in Figure 2. No clear tendency is visible by varying the kV, which is a confirmation of the quality of the standardless analysis at the used EDS spectrometer. The results of this study demonstrate the reliability of the reference measurement protocol for SEM/EDS to be introduced into ISO/DTS 23359, including the dedicated sample preparation, particularly for the cases when the concentration of the GO flakes in stock liquid suspension is low. Further, also the consideration of this GO material as one of the very few available as a commercial material on the market as the very first GO reference material with regard to its morphology as well as chemical composition. Both the standard measurement procedure and the candidate reference material will immensely contribute to characterise reliably the chemical composition of graphene-related 2D materials with SEM/EDS as one of the most widely used methods in analytical laboratories. T2 - Microscopy and Microanalysis 2025 CY - Salt Lake City, UTAH, USA DA - 27.07.2025 KW - Graphene oxide flakes KW - SEM/EDS KW - XPS KW - O/C ratio KW - Impurities PY - 2025 AN - OPUS4-64085 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hodoroaba, Vasile-Dan T1 - Physical-chemical Characterization of Graphene-Related 2D Materials: Development of Approaches for Reliable Quantification N2 - An accurate characterisation of the morphological, structural, and chemical properties of nano and advanced materials is key for the understanding of the material functionality and constitutes the basis for future optimisation or even prediction of the product performance. Further, the correlation of the physical-chemical properties with results from biological testing leads to an understanding of the potential toxicological effects so that a minimisation of the materials risks becomes possible. The presentation will highlight with examples the importance of the selection of the relevant parameters/descriptors and particularly their measurement for the reliable characterisation of the morphology, structure, and chemistry of graphene-related 2D-materials (GR2M’s) [1-3]. One crucial aspect is also one of most challenging ones in the characterisation chain: the proper sample preparation, which shall be tailored to the accurate measurement of the defined analytical parameter. Practical examples of measurement of morphological descriptors of GR2M’s, such as equivalent circular diameter (ECD), minimum and maximum Feret, and aspect ratio with electron microscopy, or of the thickness with atomic force microscopy (AFM) will be showed, together with quantitative chemical characterisation with X-ray photoelectron spectroscopy (XPS) and, newly, with energy-dispersive X-ray spectroscopy with a scanning electron microscope (SEM/EDX) [4] by evaluating accurately the elemental content as the ratio of O/C and the composition of impurities. Another relevant, but challenging part of the characterisation of GR2M’s, particularly as the final products containing mostly low amounts of GR2M’s, is the analysis of homogeneity of the chemical composition by sensitive imaging methods. Examples of successful analysis with secondary ion mass spectrometry (SIMS), even if not quantitative, will be showed. T2 - SaferWorldbyDesign Webinars CY - Online meeting DA - 25.03.2025 KW - Graphene-related 2D materials KW - Standardisation KW - Interlaboratory comparison KW - Physico-chemical characterisation PY - 2025 UR - https://saferworldbydesign.com/webinars/ AN - OPUS4-62791 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hodoroaba, Vasile-Dan T1 - Quantitative EDS analysis on graphene related 2D materials N2 - The elemental analysis of solid matter by means of the Energy-Dispersive X-Ray Spectrometry (EDS) is meanwhile posible as a quick (seconds!) and more and more accurate analysis via standardsless (instantaneous) quantification. The sensitivity & quantification accuracy for light elements (C, O,..) has significantly increased in the recent years. The availability via table-top SEMs with incorporated EDS is also enhanced. Further, the EDS analysis at an SEM is well-standardized, see ISO/TC 202 Microbeam Analysis & VAMAS/ TWA 37 Quantitative Microstructural Analysis in good liaisonships with ISO/TC 229 Nanotechnologies. It is demostrated that key parameters such as oxygen-to-carbon atomic-% ratio and impurities can be realibly measured, with XPS as a reference method. Various EDS spectrometers and analysis conditions are tested and the validity of the EDS quantification of an ionic liquid of well-defined chemical composition is demonstrated. Next steps are to launch a corresponding VAMAS interlaboratory comparison and to discuss within ISO/TC 229 towards inclusion of EDS as a routine method for the elemental analysis of GR2M into the ISO/TS 23359 Nanotechnologies — Chemical characterization of GR2Ms in powders and suspensions. T2 - Annual Microscopy Community Meeting for the National Research Council in Canada CY - Online meeting DA - 18.11.2025 KW - Graphene-related 2D materials (GR2M) KW - Elemental analysis KW - Light elements KW - SEM/EDS KW - Standardisation PY - 2025 AN - OPUS4-64766 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - RPRT A1 - Knigge, Xenia A1 - Radnik, Jörg T1 - Advanced materials for the energy transition N2 - The climate crisis is the burning issue of our time. In order to avert the impending consequences, global efforts are being made in a wide variety of social and scientific fields. This report looks at a small part of these efforts, a technical aspect, namely the question of which AdMa are currently considered in techniques to support the energy transition. AdMa, i.e. materials that are rationally designed to have new or enhanced properties, and/or targeted or enhanced structural features, are used in all sectors of the energy transition. Questions of energy generation, storage and saving are considered here. This report is based on literature research and contains a general compilation of various AdMa that are used in the energy transition or are being researched for this purpose. From this compilation, ten materials that are considered particularly relevant for various reasons were selected and examined in more detail in relation to their use. The specific question here lies in the conflicting objective that the development of technologies for the energy transition is welcomed, but the use of AdMa may entail possible challenges in view of chemical safety as well as sustainability and circular economy. KW - Energy generation KW - Energy saving KW - Eneergy storage KW - Energy transportation PY - 2025 DO - https://doi.org/10.60810/openumwelt-7853 SN - 1862-4804 VL - 83 SP - 1 EP - 64 PB - Umweltbundesamt CY - Dessau-Roßlau AN - OPUS4-63529 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Schilling, Markus T1 - Towards Structured Data Spaces: Prototypical Application of Semantic Technologies as a Driver for Innovation in Materials Science N2 - In the pursuit of advancing development and digitalization within materials science, ensuring quality assurance, interoperability, and adherence to FAIR principles is significant. To address these aspects, semantic technologies are employed for storage, processing, and contextualization of data, offering machine-actionable and human-readable knowledge representations crucial for data management. This presentation showcases the prototypical application of generic approaches of knowledge representation in materials science. It includes the design and documentation of graph patterns that may be compiled into rule-based semantic shapes. The development and application of the PMD Core Ontology 3.0 (PMDco 3.0) tailored for materials science is highlighted. Its integration into daily lab life is demonstrated through its functional incorporation into electronic lab notebooks (ELN). Examples of material processing and standardized mechanical testing illustrate how knowledge graph operations enhance ELN capabilities, providing a generalizable unified approach for managing diverse experimental data from different sources with automation potentials. T2 - TMS Specialty Congress 2025 CY - Anaheim, CA, USA DA - 15.06.2025 KW - Semantic Data KW - Data Integration KW - Digitalization KW - Data Interoperability KW - Plattform MaterialDigital PY - 2025 AN - OPUS4-63401 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Fernandez-Poulussen, D. A1 - Hodoroaba, Vasile-Dan T1 - Holistic, reliable and practical Characterization Framework for Graphene Family Materials, a correlated approach including Imaging based techniques N2 - ACCORDs is an Horizon Europe project working in the development of an imaging-based characterization framework (ACCORDs framework) for the holistic correlative assessment of Graphene Family Materials (GFMs) as a representative of 2D nanomaterials (NMs) to assess and predict 2D NMs health and environmental risks. The ACCORDs framework will operationalise safe and sustainable by design (SSbD) strategies proposed in past or ongoing H2020 projects or within OECD by correlating low-, medium-, and high-resolution physico-chemical-biological imaging-based methods with non-imaging methods in a tiered approach. ACCORDs will deliver the ACCORDs framework and user guidance, new imaging-based characterisation methods, reference in vitro tests, new reference 2D NMs for different matrices, a new minimum information reporting guideline for FAIR data sharing and reuse of images as well as an atlas with reference images for diagnostics of compromised safety of GFMs/GFM products. The new guidelines and standard proposals will be submitted to standardisation bodies to allow creation of regulatory ready products. The novelty of ACCORDs is in translating the principles of medical imaging-based diagnostics to 2D material hazard diagnostics. ACCORDs will accelerate industrial sectors in the area of aviation, marine construction, drone production, flexible electronics, photovoltaics, photocatalytics and print inks-based sensors. The value ACCORDs proposes to the graphene industry are practical, easy, imaging-based tools for GFM quality monitoring next to the production line with a possibility to be correlated with advanced highresolution imaging characterization methods in case hazard i.e. deviation from controls (benchmark values) are diagnosed. The ACCORDs framework and tools will contribute to the European Green Deal by addressing the topic: “Graphene: Europe in the lead” and to a new European strategy on standardization, released on 2nd February, 2022 T2 - Joint Regulatory Risk Assessors Summit – Advancing Safety & Sustainability Assessments of Advanced Materials CY - Paris, France DA - 19.06.2025 KW - Graphene-related 2D materials (GR2M) KW - Imaging KW - SSbD KW - ACCORDs PY - 2025 UR - https://macrame-project.eu/macrame-meetings-workshops/jointrras/#Agenda AN - OPUS4-63660 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Radnik, Jörg T1 - Investigation of Fe-Ni-O nanoparticles for water splitting N2 - This study investigates the effect of varying iron-to-nickel ratios on the catalytic performance of Fe-Ni oxide nanoparticles (NPs) for the oxygen evolution reaction (OER). Addressing the issue of high energy wastage due to large overpotentials in OER, we synthesized and characterized different NP catalysts with different Fe: Ni oxide ratios. Transmission Electron Microscopy (TEM), Energy Dispersive X-ray Spectroscopy (EDS), and X-ray Diffraction (XRD) were employed to determine the morphology, elemental and phase composition of the NPs. Furthermore, in-depth profiling with X-rayPhotoelectron Spectroscopy (XPS) and Hard X-ray Photoelectron Spectroscopy (HAXPES) revealedthat iron predominantly exists as oxide, while nickel exhibits both metallic and oxidic forms depending on the Fe content. XPS indicated an enrichment of iron at the NP surface, whereas HAXPES and EDSdata agreed on the bulk stoichiometry. T2 - PhI European User Meeting 2025 CY - Eibelstadt, Germany DA - 29.04.2025 KW - Oxygen evolution reaction KW - In depth analysis KW - (Hard) X-ray Photoelectron Spectroscopy PY - 2025 AN - OPUS4-63334 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Fagan, J. A1 - Hodoroaba, Vasile-Dan T1 - VAMAS TWA 34 Nanoparticle Populations Combined Projects P15 and P16 N2 - The progress in the VAMAS Project #15 "Measurement of particle size and shape distribution of bipyramidal titania including deposition from liquid suspension" within TWA 34 Nanoparticle Populations is presented with highlight of the following points: - Determine and compare particle size and shape distribution by means of electron microscopy (SEM, TEM, STEM-in-SEM), atomic force microscopy (AFM) and small angle X-ray scattering (SAXS). - Determine uncertainty induced by deposition protocol from liquid suspension with comparison to known values from a prior ILC with already deposited nanoparticles on TEM grids. - Provide comparative validation of protocols for the techniques other than TEM. Further, the VAMAS/TWA 34 Project #16 "Measurement of (relative) number concentration of bimodal silica nanoparticles including deposition from liquid suspension" is presented. Follwowing points are discusssed: - Validate the performance of imaging methods to measure the relative number concentration by electron microscopy (SEM, TEM) and atomic force microscopy (AFM) and two modes of bimodal (30 and 60 nm) silica nanoparticles - Validate the performance of small angle X-ray scattering (SAXS) for the traceable measurement of the number concentration of the two modes. - Discussion of sample preparation issues - Publication of the results in 2026 T2 - Versailles Project on Advanced Materials and Standards (VAMAS) 50th Steering Committee Meeting CY - London, United Kingdom DA - 14.09.2025 KW - VAMAS KW - Interlaboratory comparison KW - Particle size and shape distribution KW - Particle number concentration KW - Standardisation PY - 2025 UR - https://www.vamas.org/twa34/index.html AN - OPUS4-64234 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hodoroaba, Vasile-Dan T1 - VAMAS Regional Report Advanced Materials Germany 2025 N2 - Regional standardisation activities and how VAMAS can help in any way to promote activities are reported. Activities related to organisational updates, government initiatives/priorities (especially related to Advanced Materials), details of any strategy documents publicly available, networks within Germany and how we engage are presented. T2 - Versailles Project on Advanced Materials and Standards (VAMAS) 50th Steering Committee Meeting CY - London, United Kingdom DA - 14.09.2025 KW - VAMAS KW - Interlaboratory comparison KW - Advanced materials KW - Standardisation PY - 2025 AN - OPUS4-64232 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Narayanan, M.M. A1 - Nicolai, M. A1 - Prager, J. T1 - C9-a5 - Optimization of Low-Frequency Shear Wave Transducers for Guided Wave Applications N2 - Development of ultrasonic transducers for the excitation of a torsional mode T(0,1) mode in a large pipe of the material typical of actual oil/gas pipelines is discussed. Towards this,16 ultrasonic transducers are designed and fabricated using shear plates of PIC 255 material, backing mass of tungsten-epoxy composite and brass shims as wear plates. The transducers are qualified using Laser Doppler Vibrometry. Then, the transducers are embedded in a springloaded ring and tested on a pipe using a multi-channel ultrasonic system. The results show the successful excitation of T(0,1) mode and it is seen to propagate for distance of 60 m with a good SNR. T2 - 2025 ICU PADERBORN - 9th International Congress on Ultrasonics CY - Paderborn, Germany DA - 21.09.2025 KW - Ultrasonic guided waves KW - Torsional mode KW - Shear PZT plates KW - Ring array transducer design KW - Pipe testing PY - 2025 DO - https://doi.org/10.5162/Ultrasonic2025/C9-a5 SP - 223 EP - 226 PB - AMA Service GmbH AN - OPUS4-65356 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Zeipert, H. A1 - Nellius, T. A1 - Schönlau, N. A1 - Wippermann, M. A1 - Claes, L. A1 - Henning, B. A1 - Nicolai, Marcel A1 - Prager, J. T1 - C6-a3 - Monitoring the curing process of adhesive bonds using selective excitation of guided ultrasonic waves N2 - A measurement setup for the selective excitation of guided ultrasonic waves in adhesively bonded plates is introduced. Changes of the dispersive behaviour of the guided waves during the curing process is known to be accompanied by a change in the propagating waves group velocities. The proposed measurement setup is used to monitor that change during the curing process of an aluminium-epoxy-polycarbonate bond. T2 - 2025 ICU PADERBORN - 9th International Congress on Ultrasonics CY - Paderborn, Germany DA - 21.09.2025 KW - Ultrasonic guided waves KW - Selective excitation KW - Non-destructive testing KW - Adhesive bonding KW - Condition monitoring PY - 2025 DO - https://doi.org/10.5162/Ultrasonic2025/C6-a3 SP - 207 EP - 210 PB - AMA Service GmbH AN - OPUS4-65357 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Dudziak, Mateusz A1 - Riechers, Birte A1 - Maaß, Robert A1 - Michalchuk, Adam A1 - Schönhals, Andreas A1 - Szymoniak, Paulina T1 - Beyond conventional calorimetry: Unlocking thermal characterization with fast scanning techniques N2 - Fast scanning calorimetry (FSC) has emerged as a transformative technique in thermal analysis, enabling the investigation of rapid and kinetically driven thermal transitions that are inaccessible to conventional differential scanning calorimetry. This review highlights the capabilities enabled by FSC for studying a wide range of materials under extreme thermal conditions, including polymers, pharmaceuticals, metallic glasses, nanocomposites, and hydrogels. By employing ultrafast heating and cooling rates, FSC allows for the suppression of crystallization, resolution of weak transitions, and analysis of thermally labile or size-limited samples. The technique is particularly valuable for probing glass transitions, relaxation phenomena, and phase behavior in systems with complex morphologies or confined geometries. Case studies demonstrate the use of FSC in characterizing vitrification, physical aging, and interfacial dynamics, as well as its application in emerging fields such as additive manufacturing, supramolecular systems, and neuromorphic materials. Together, these examples underscore the role that FSC plays in advancing the understanding of structure-property relationships across diverse material classes. KW - Flash DSC KW - Calorimetry KW - Glass transition PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-647405 DO - https://doi.org/10.1016/j.tca.2025.180177 VL - 754 SP - 1 EP - 14 PB - Elsevier B.V. AN - OPUS4-64740 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Kossatz, Philipp A1 - Mezhov, Alexander A1 - Andresen, Elina A1 - Prinz, Carsten A1 - Schmidt, Wolfram A1 - Resch-Genger, Ute T1 - Assessing the Applicability of Lanthanide-Based Upconverting Nanoparticles for Optically Monitoring Cement Hydration and Tagging Building Materials N2 - Chemically stable, lanthanide-based photon upconversion micro- and nanoparticles (UCNPs) with their characteristic multicolor emission bands in the ultraviolet (UV), visible (vis), near-infrared (NIR), and short-wave infrared (SWIR) arepromising optical reporters and barcoding tags. To assess the applicability of UCNPs for the monitoring of early stage cement hydration processes and as authentication tags for cementitious materials, we screened the evolution of the luminescence of Selfmade core-only NaYF4:Yb,Er UCNPs and commercial μm-sized Y2O2S:Yb,Er particles during the first stages of cement hydration, which largely determines the future properties of the hardened material. Parameters explored from the UCNP side included particle size, morphology, surface chemistry or coating, luminescence properties, and concentration in different cement mixtures. From the cement side, the influence of the mineral composition of the cement matrix was representatively examined for ordinary Portland cement (OPC) and its constituents tricalcium aluminate (C3A), tricalcium silicate (C3S), and gypsum at different water to cement ratios. Based on reflection and luminescence measurements, enabling online monitoring, which were complemented by XRD and isothermal heat-flow calorimetric measurements to determine whether the incorporation of these particles could impair cement hydration processes, well suited lanthanide particle reporters could be identified as well as application conditions. In addition, thereby the reporter influence on cement hydration kinetics could be minimized while still preserving a high level of information content. The best performance for the luminescence probing of changes during early stage cement hydration processes was observed for 25 nm-sized oleate (OA)-coated UCNPs added in a concentration of 0.1 wt %. Higher UCNP amounts of 1.0 wt % delayed cement hydration processes size- and surface coatingspecifically in the first 24 h. Subsequent luminescence stability screening studies performed over a period of about one year support the applicability of UCNPs as optical authentication tags for construction materials. KW - Quality assurance KW - Fluorescence KW - Nano KW - Particle KW - Synthesis KW - Quantum yield KW - NIR KW - Mechanism KW - Characterization KW - XRD KW - Calorimetry KW - Advanced material KW - Cement KW - Monitoring KW - Surface KW - Size KW - Lifetime KW - Barcode KW - Lanthanide KW - Upconversion KW - Encoding KW - Method PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-638318 DO - https://doi.org/10.1021/acsomega.5c02236 SN - 2470-1343 VL - 10 IS - 29 SP - 31587 EP - 31599 PB - ACS Publications CY - Washington, DC AN - OPUS4-63831 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Schilling, Markus T1 - Semantic Technologies in Action: Integrating Mechanical and Microstructure Data in MSE N2 - Semantic technologies (ST) are a powerful tool for storing, processing, and querying data in a contextualized and interoperable manner. They enable machine-actionable and human-readable knowledge representations essential for advanced data management, retrieval, and reuse. As one of the key factors within the frame of the collaborative project platform MaterialDigital (PMD), the establishment of a virtual material data space and the semantic modeling of hierarchical, process-dependent material data is aimed at to serve as best-practice examples of knowledge representation through ontologies and knowledge graphs. In this presentation, the application of ST to a specific use case from the field of materials sciences and engineering (MSE) is demonstrated: the integration and analysis of data related to a 2000 series age-hardenable aluminum alloy. By semantically representing mechanical and microstructural data obtained from tensile tests and dark-field transmission electron microscopy across various aging times, an expandable knowledge graph was constructed that is aligned with the PMD Core Ontology (PMDco) and enriched through the Tensile Test (TTO) and Precipitate Geometry Ontologies. This semantically integrated dataset enables advanced analytical capabilities via SPARQL queries and reveals microstructure–property relationships consistent with the well-known Orowan mechanism. The approach highlights the potential of semantic data integration to support FAIR data principles and to foster a more data-centric and interoperable research infrastructure in MSE. T2 - MSE Research Data Forum 2025 CY - Siegburg, Germany DA - 08.07.2025 KW - Semantic Data KW - Data Integration KW - Digitalization KW - Data Interoperability PY - 2025 AN - OPUS4-63666 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Oskoei, Párástu A1 - Afonso, Rúben A1 - Bastos, Verónica A1 - Nogueira, João A1 - Keller, Lisa-Marie A1 - Andresen, Elina A1 - Saleh, Maysoon I. A1 - Rühle, Bastian A1 - Resch-Genger, Ute A1 - Daniel-da-Silva, Ana L. A1 - Oliveira, Helena T1 - Upconversion Nanoparticles with Mesoporous Silica Coatings for Doxorubicin Targeted Delivery to Melanoma Cells N2 - Melanoma is one of the most aggressive skin cancers and requires innovative therapeutic strategies to overcome the limitations of conventional therapies. In this work, upconversion nanoparticles coated with mesoporous silica and functionalized with folic acid (UCNP@mSiO2-FA) were developed as a targeted nanocarrier system for the delivery of doxorubicin (DOX). The UCNPs were synthesized via thermal decomposition, coated with mesoporous silica shells, and functionalized with folic acid (FA) to enable receptor-mediated targeting. DOX was then loaded into the mesoporous silica coating by adsorption, yielding UCNP@mSiO2-FA-DOX. The different UCNPs were characterized for size, composition, colloidal stability, and loading and release of DOX. This comprehensive physicochemical characterization confirmed a high DOX loading efficiency and a slightly increased drug release under acidic conditions, mimicking the tumour microenvironment. In vitro assays using four melanoma cell lines (A375, B16-F10, MNT-1, and SK-MEL-28) revealed an excellent biocompatibility of UCNP@mSiO2-FA and a significantly higher cytotoxicity of UCNP@mSiO2-FA-DOX compared to unloaded UCNPs, in a dose-dependent manner. Cell cycle analysis demonstrated G2/M phase arrest after treatment with UCNP@mSiO2-FA-DOX, confirming its antiproliferative effect. Overall, UCNP@mSiO2-FA-DOX represents a promising nanoplatform for targeted melanoma therapy, combining active tumour targeting and enhanced anticancer efficacy. KW - Fluorescence KW - Synthesis KW - Nano KW - Particle KW - Silica KW - Cell KW - Uptake KW - Drug KW - Characterization KW - DOX KW - Imaging KW - Toxicity KW - Release KW - pH PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-653596 DO - https://doi.org/10.3390/molecules31010074 SN - 1420-3049 VL - 31 IS - 1 SP - 1 EP - 18 PB - MDPI AG AN - OPUS4-65359 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Madbouly, Loay Akmal T1 - Chemical analysis of commercial functionalized graphene along the production process N2 - Graphene has been commercialized for over a decade. For many applications like flexible electronics, coating of different materials like paper or for textiles, it used in the form of suspensions or inks. Functionalization enables tailoring the properties of graphene, such as the sheet resistance. X-ray photoelectron spectroscopy (XPS) and Raman spectroscopy are used to characterize the chemical composition of graphene flakes, functionalized and otherwise. In this study, we investigate the following set of commercial materials: fluorine-functionalized graphene (F-graphene) and nitrogen-functionalized graphene (N-graphene) as well as unfunctionalized graphene (G-graphene, as the starting material) in the forms of powders, suspensions, and inks, the latter as the final commercial product. Raman spectroscopy and XPS are complementary techniques. Our results obtained from Raman spectroscopy confirmed the existence of graphene structures in all samples investigated and provided a comparative insight on the structural defects between samples. XPS was used to investigate the chemical states of elements in graphene, such as sp2 and sp3 hybridization states of carbon, as well as the chemical effect of functionalization on graphene. High resolution XPS analysis was performed for C 1s, F 1s and N 1s core-levels for all the graphene samples. The XPS results showed the elemental composition and the impurities of each sample. All powders showed less presence of carboxyl groups, compared to their respective suspensions and inks. F-functionalized suspension and inks showed a significant decrease in the at-% of fluorine relative to the powder. These valuable insights, particularly when correlated, allowed the tracking of the structural and chemical changes of graphene along its production process. T2 - 3rd FUB Nano Colloquium CY - Berlin, Germany DA - 15.07.2025 KW - Functionalized graphene KW - Graphene-related 2D materials (GR2M) KW - Raman Spectroscopy KW - XPS KW - Inks PY - 2025 AN - OPUS4-64116 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Madbouly, Loay Akmal A1 - Hodoroaba, Vasile-Dan A1 - Radnik, Jörg T1 - Raman Spectroscopy and X-ray Photoelectron Spectroscopy of Commercial Functionalized Graphene N2 - Graphene has found widespread commercial use, particularly in flexible electronics and coatings for substrates such as paper and textiles, in the form of suspensions and inks (Zhang et al., 2017). Functionalization of graphene allows fine-tuning of properties like electrical conductivity. Structural and chemical features of graphene materials are typically analyzed by Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). While Raman spectroscopy plays a critical role in identifying the presence of graphene and characterizing its structural defects (Pollard et al., 2017), XPS examines the chemistry of graphene. This study investigates three types of graphene materials — graphene (unfunctionalized, G-graphene), fluorine-functionalized graphene (F-graphene), and nitrogen-functionalized graphene (N-graphene) — across three physical forms: powders, suspensions, and embedded in inks. Functionalization was performed via plasma treatment of G-graphene with fluorine or ammonia gases. Suspensions were obtained by dispersing powders in distilled water, while inks were formulated using diacetone alcohol, carbon black, and graphene. Raman spectroscopy analysis confirmed the graphitic nature of all materials and revealed differences in defect density across different forms. The characteristic D, G, and D’ bands varied in relative intensity, offering insight into structural integrity and functionalization effects. XPS measurements examined core-level spectra (C 1s, F 1s, N 1s), revealing chemical bonding environments and hybridization states, including the sp² and sp³ states. A notable decline in fluorine content in F-graphene suspensions and inks, relative to powders, was observed. Existence of organic fluorine and total absence of metallic fluorine were observed. Raman spectroscopy and XPS data provided a correlated view of structural and chemical evolution through the graphene production chain. T2 - Joint Regulatory Risk Assessors Summit – Advancing Safety & Sustainability Assessments of Advanced Materials CY - Paris, France DA - 19.06.2025 KW - Graphene-related 2D materials (GR2M) KW - Inks KW - Raman Spectroscopy KW - XPS KW - Functionalized graphene PY - 2025 UR - https://macrame-project.eu/macrame-meetings-workshops/jointrras/#Agenda AN - OPUS4-63661 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Tamang, S. A1 - Wegner, Karl David A1 - Reiss, P. ED - Alivisatos, P. ED - Jang, E. ED - Ma, R. T1 - Quantum Dot Material Systems, Compositional Families N2 - Following the discovery of the quantum confinement effect in the early 1980s, it took more than 10 years to be able to synthesize monodisperse colloidal quantum dots (QDs) using organometallic chemistry approaches. The researchers behind these pioneering works, Alexey Ekimov, Louis Brus, and Moungi Bawendi, were awarded the Nobel Prize in Chemistry in 2023, exactly 30 years after the seminal report on the preparation of cadmium chalcogenide QDs. From the synthetic point of view, this approach, relying on the fast injection of a chalcogenide precursor dissolved in a tertiary phosphine into a hot solution of the cadmium precursor in a coordinating solvent (trioctylphosphine oxide, TOPO) acting at the same time as surface ligand, was revolutionary. It enabled the fast synthesis of wellcrystallized CdS, CdSe, and CdTe QDs of low size dispersion and high colloidal stability, whose size and hence optical and electronic properties could be conveniently tuned with the reaction time. Due to the comparable ease of this method and the later developed shelling procedures with ZnS, ZnSe, CdS, and mixtures or alloys of these materials, CdSe has become the workhorse for the entire QD field, covering the whole visible range of absorption and emission. Meanwhile, several breakthroughs have been achieved, which enabled us to bring QDs to their maturity of today and integrate them in several applications, in particular those relying on their exceptional luminescence properties, such as biological imaging as well as displays and screens. For such real-life applications, the quest for less toxic, safer-to-use, and environmentally friendly materials is of utmost importanceand a highly active research field. The use of cadmium- and lead-based materials is severely restricted by regulations such as the RoHS directive of the European Union: the maximum concentrations of lead and cadmium are 0.1 and 0.01% by weight, respectively, in all homogeneous materials in electrical and electronicequipment. Several families of alternative materials have been explored, with the most important ones for display technologies being indium phosphide (InP)- and ternary chalcopyrite-type QDs. KW - Quantum dots KW - Photoluminescence KW - LED KW - Display technology PY - 2025 SN - 978-1-394-18187-2 SP - 23 EP - 62 PB - John Wiley & Sons Ltd. AN - OPUS4-64675 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - INPR A1 - Döring, Sarah A1 - Wulfes, Birte S. A1 - Atanasova, Aleksandra A1 - Jaeger, Carsten A1 - Walzel, Leopold A1 - Tscheuschner, Georg A1 - Flemig, Sabine A1 - Gawlitza, Kornelia A1 - Feldmann, Ines A1 - Konthur, Zoltán A1 - Weller, Michael G. T1 - Corundum Particles as Trypsin Carrier for Efficient Protein Digestion N2 - Reusable enzyme carriers are valuable for proteomic workflows, yet many supports are expensive or lack robustness. This study describes the covalent immobilization of recombinant trypsin on micrometer-sized corundum particles and assesses their performance in protein digestion and antibody analysis. The corundum surface was cleaned with potassium hydroxide, silanized with 3-aminopropyltriethoxysilane and activated with glutaraldehyde. Recombinant trypsin was then attached, and the resulting imines were reduced with sodium cyanoborohydride. Aromatic amino acid analysis (AAAA) estimated an enzyme loading of approximately 1 µg/mg. Non-specific adsorption of human plasma proteins was suppressed by blocking residual aldehydes with a Tris-glycine-lysine buffer. Compared with free trypsin, immobilization shifted the temperature optimum from 50 to 60 °C and greatly improved stability in 1 M guanidinium hydrochloride. Activity remained above 80 % across several reuse cycles, and storage at 4 °C preserved functionality for weeks. When applied to digesting the NISTmAb, immobilized trypsin provided peptide yields and sequence coverage comparable to soluble enzyme and outperformed it at elevated temperatures. MALDI-TOF MS analysis of Herceptin digests yielded fingerprint spectra that correctly identified the antibody and achieved >60 % sequence coverage. The combination of low cost, robustness and analytical performance makes corundum-immobilized trypsin an attractive option for research and routine proteomic workflows. KW - Aluminum oxide KW - Mass spectrometry KW - Enzyme immobilization KW - Antibodies KW - Protein quantification PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-647944 DO - https://doi.org/10.20944/preprints202510.2002.v1 SP - 1 EP - 22 PB - Preprints.org AN - OPUS4-64794 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -