TY - JOUR
A1 - Alfeld, M.
A1 - Eckhardt, H.-S.
A1 - Kraft, J.
A1 - Maiwald, Michael
A1 - Meermann, Björn
A1 - Merz, K.
A1 - Prikler, S.
A1 - Richert, J.
A1 - Steiner, G.
A1 - von Tümpling, W.
T1 - Trendbericht Analytische Chemie
N2 - Zusätzlich zu Methodenentwicklung, Miniaturisierung und Kopplungsverfahren zeigen sich die Hyperspektroskopie zusammen mit Imaging‐Verfahren, der Einzelmolekülnachweis und der Einsatz von 3‐D‐Druckern als neue Schwerpunkte. Hinzu kommen künstliche Intelligenz bei Sensoren, Bildgebungsverfahren und Prozesssteuerung sowie die Vernetzung von Analyse‐ und Laborgeräten. Trends und Forschungsthemen aus der analytischen Chemie, zusammengestellt von elf Autoren, koordiniert von Günter Gauglitz.
KW - Multielementanalytik
KW - Multimodale Analytik
KW - Kristallolgraphie
KW - Prozessanalytik
KW - Prozessindustrie
KW - Industrielle Analytik
KW - Chemometrik
KW - Chemometrie
PY - 2020
DO - https://doi.org/10.1002/nadc.20204095786
SN - 1868-0054
VL - 68
IS - 4
SP - 52
EP - 60
PB - Wiley
CY - Weinheim
AN - OPUS4-50609
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Maiwald, Michael
T1 - The internet of things in the lab and in process - The digital transformation challenges for the laboratory 4.0
T1 - Das Internet of Things in Labor und Prozess - Herausforderungen des digitalen Wandels für das Labor 4.0
N2 - It is a fact that much of the time spent on analytical laboratory instrumentation these days goes into system maintenance. Digital transformation could give us more time again for creativity and our actual laboratory work – if we shape it the right way.
N2 - Fakt ist: Einen Großteil der Zeit, der an analytischen Laborgeräten verbracht wird, nimmt heute die Systempflege in Anspruch. Der digitale Wandel kann uns endlich wieder mehr Zeit für Kreativität und die eigentliche Laborarbeit geben – wenn wir ihn richtig gestalten.
KW - Lab of the Future
KW - Digitalisation
KW - Automation
KW - Data Analysis
KW - Instrument Communication
KW - Labor der Zukunft
KW - Digitale Transformation
KW - Automatisierung
KW - Gerätekommunikation
PY - 2020
IS - 4
SP - 1
EP - 3
PB - Lumitos AG
CY - Darmstadt
AN - OPUS4-50618
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Maiwald, Michael
T1 - On the way to the cyber-physical lab
T1 - Auf dem Weg zum cyber-physical Lab
N2 - Laboratories tend to be central hubs for chemical, biotechnological, pharmaceutical or foodstuff production. They play a key role in research and development, chemical analysis, quality assurance, maintenance and process control. For process development and optimization, process analytical technology (PAT) has proven to be a powerful tool to improve our understanding of processes, increase productivity, reduce waste and costs and shorten processing times.
N2 - Im Allgemeinen sind Laboratorien zentrale Drehscheiben für die chemische, biotechnologische, pharmazeutische oder Lebensmittelproduktion. Sie spielen eine Schlüsselrolle in Forschung und Entwicklung, chemischer Analytik, Qualitätssicherung, Instandhaltung und Prozesskontrolle. Für die Prozessentwicklung und -Optimierung hat sich die Prozessanalysentechnik (PAT) als leistungsfähiges Werkzeug erwiesen, um das Prozessverständnis zu verbessern, die Produktivität zu steigern, Abfall und Kosten zu reduzieren und die Prozesszeit zu verkürzen.
KW - Lab of the Future
KW - Digitalisation
KW - Cyber-physical Lab
KW - Smart Laboratoy
PY - 2020
SP - 1
EP - 3
PB - Lumitos AG
CY - Darmstadt
AN - OPUS4-51036
LA - mul
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Dittmann, Daniel
A1 - Lucke, T.
A1 - Ruhl, A. S.
A1 - Winzenbacher, R.
A1 - Jekel, M.
A1 - Braun, Ulrike
T1 - Untersuchungen zu biologischen, organischen und anorganischen Veränderungen granulierter Aktivkohlen während der Trinkwasseraufbereitung
N2 - Untersuchungen zu biologischen, organischen und anorganischen Veränderungen granulierter Aktivkohlen während der Trinkwasseraufbereitung des Landeswasserversorgers Langenau.
KW - Thermogravimetrie
KW - Trinkwasser
KW - Wasseraufbereitung
KW - Aktivkohle
PY - 2020
SN - 0083-6915
VL - 118
IS - 2
SP - 47
EP - 50
PB - Wiley-VCH Verlag GmbH & Co. KGaA
AN - OPUS4-51434
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Ecke, Alexander
A1 - Bohm, Konrad
A1 - Schneider, Rudolf
T1 - Magnetpartikelbasierte Immunoassays als vielseitiges Werkzeug für die Umweltanalytik
N2 - Der Bedarf nach schnellen und kostengünstigen Analysemethoden in der (Trink-)Wasseranalytik steigt mit dem zunehmenden Eintrag pharmazeutisch aktiver Substanzen in die Umwelt.
Insbesondere die Kontamination mit Antibiotika erscheint neben ökotoxikologischen Effekten vor allem in Hinblick auf die Evolution resistenter Keime im Wasser besorgniserregend.
Wir berichten hier über die Entwicklung eines magnetpartikelbasierten Immunoassays (MBBA) zur Detektion des Breitbandantibiotikums Amoxicillin (AMX) in Wasserproben, der im Vergleich zum entsprechenden Enzyme-linked Immunosorbent Assay (ELISA) eine wesentlich kürzere Analysendauer sowie einen breiteren Messbereich mit niedrigerer Nachweisgrenze aufweist. Das angewendete Assayprinzip ist dabei leicht auf weitere Analyten übertragbar und ermöglicht die Implementierung in einen Immunosensor.
KW - Magnetpartikel
KW - Amoxicillin
KW - Immunoassay
KW - Wasser
KW - Antikörper
PY - 2021
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-527366
UR - https://www.gdch.de/netzwerk-strukturen/fachstrukturen/umweltchemie-und-oekotoxikologie/publikationen/mitteilungen/archiv/2021.html
SN - 1618-3258
VL - 27
IS - 2
SP - 48
EP - 51
PB - Gesellschaft Deutscher Chemiker (GDCh)
CY - Frankfurt/Main
AN - OPUS4-52736
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Gehrenkemper, Lennart
A1 - Simon, Fabian
A1 - Meermann, Björn
T1 - PFAS-Summenparameteranalytik - Neue analytische Methoden zum Nachweis von per- und polyfluorierten Verbindungen in der Umwelt
N2 - Per- und polyfluorierte Alkylverbindungen (PFAS) sind sehr persistent und reichern sich in der Umwelt und im menschlichen Organismus in immer höheren Konzentrationen an. PFAS stellen deshalb eine große Gefährdung für Mensch und Umwelt dar. Eingesetzt werden sie u. a. als wasser- und fettabweisende Beschichtung in z. B. der Papier- und Textilindustrie und gelangen so während Produktion, Gebrauch und Entsorgung u. a. in den Wasserkreislauf. PFAS konnten sogar in der arktischen Umwelt in relevanten Konzentrationen detektiert werden und zählen somit zu den „emerging pollutants“. Ein prominenter Vertreter der PFAS stellt Perfluoroctansulfonsäure (PFOS) dar - die jedoch bereits im Anhang des Stockholmer Abkommen gelistet wurde und deren Einsatz somit stark eingeschränkt bzw. verboten ist. Im Hinblick auf die Vielzahl von Verbindungen werden neue analytische Methoden benötigt, die eine PFAS-Belastungssituation möglichst umfassend und nachweisstark widerspiegeln, um zukünftig mögliche Grenzwerte ableiten zu können.
KW - PFAS
KW - HR-CS-GFMAS
KW - CIC
KW - Fluor
KW - Oberflächenwasser
PY - 2021
UR - https://analyticalscience.wiley.com/do/10.1002/was.00080223
SN - 0016-3538
VL - 2021
IS - März
SP - was.00080223, 2
EP - 4
PB - Wiley-VCH
CY - Weinheim
AN - OPUS4-52261
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Ogrinc, N.
A1 - Rossi, A. M.
A1 - Durbiano, F.
A1 - Becker, Roland
A1 - Milavec, M.
A1 - Bogozalec Kosir, A.
A1 - Kakoulides, E.
A1 - Ozer, H.
A1 - Akcadag, F.
A1 - Goenaga-Infante, H.
A1 - Quaglia, M.
A1 - Mallia, S.
A1 - Umbricht, G.
A1 - O'Connor, G.
A1 - Guettler, B.
T1 - Support for a European metrology network on food safety Food-MetNet
N2 - This paper describes Food-MetNet, a coordinated preparatory initiative to establish the European Metrology Network on Food Safety (EMN-FS). Food-MetNet aims to establish a long-term ongoing dialogue between the metrology community and relevant stakeholders, in particular, European Union Reference Laboratories (EURLs), National Reference Laboratories (NRLs) and the Joint Research Centre (JRC). This dialogue is meant to support the collection of needs from stakeholders, the take-up of metrological research output and the development of the roadmaps needed to navigate future research.
KW - Network
KW - Metrology
KW - Food
KW - Safety
KW - Stakeholders
PY - 2021
DO - https://doi.org/10.1016/j.measen.2021.100285
VL - 18
SP - 1
EP - 4
PB - Elsevier
AN - OPUS4-53740
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Gehrenkemper, Lennart
A1 - Simon, Fabian
A1 - Meermann, Björn
T1 - Schnelle und einfache Extraktion von PFAS aus Bodenproben: Optimierte EOF-Bestimmung mittels HR-CS-GFMAS
N2 - Per- und polyfluorierte Alkylsubstanzen (PFAS) bilden eine sehr komplexe Schadstoffgruppe mit über 6300 Einzelsubstanzen, die in vielfältiger Form in die Umwelt eingetragen werden. Für ein effektives Monitoring dieser Schadstoffklasse benötigt es ein Zusammenspiel aus Summenparameter-Analytik zur hot-spot-Identifizierung und Klassifizierung von Belastungssituationen sowie einer nachgeschalteten target-Analytik zur Identifizierung von Eintragswegen, die zugleich ein tieferes Verständnis von Transformationsprozessen ermöglicht. In diesem Beitrag präsentieren wir eine optimierte Extraktions-Methode für die PFAS-Summenparameteranalytik. Mit Hilfe dieser können bisher verwendete zeit- und kostenintensive Festphasenextraktionen (SPE) umgangen und PFAS-Extraktionseffizienzen gesteigert werden. Die methodische Bestimmungsgrenze (LOQ) war mit 10,30 μg/kg (Fluor pro Bodenprobe) ausreichend für alle 9 untersuchten Realbodenproben.
KW - High resolution-continuum source-graphite furnace molecular absorption spectrometry (HR-CS-GFMAS)
KW - PFAS
KW - Per- and polyfluorinated alkyl substances (PFASs)
KW - Extractable organically bound fluorine (EOF)
KW - Solid-liquid extraction
KW - Böden
PY - 2022
UR - https://www.gdch.de/fileadmin/downloads/Netzwerk_und_Strukturen/Fachgruppen/Umweltchemie_Oekotoxikologie/mblatt/2022/Heft122.pdf
SN - 1618-3258
VL - 28
IS - 1
SP - 12
EP - 15
PB - Gesellschaft Deutscher Chemiker
AN - OPUS4-54417
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Simon, Fabian
A1 - Gehrenkemper, Lennart
A1 - Dierckes, G.
A1 - Göckener, B.
A1 - Koschorreck, J.
A1 - Meermann, Björn
T1 - Analyse von PFAS mittels (Non-)Target HRMS, dTOPA und EOF in Schwebstoff-Proben aus Zeitreihen der Umweltprobenbank
N2 - Per- und polyfluorierte Alkylverbindungen (PFAS) sind eine Substanzklasse bestehend aus mehreren tausenden Einzelverbindungen. Unter PFAS zählen alle Verbindungen, die mindestens eine perfluorierte Methyl- (-CF3) oder Methylen-Gruppe (-CF2-) besitzen. Somit zählt auch ein großer Teil der fluorierten Medikamente, Pflanzenschutzmittel oder Biozide in die PFAS-Substanzklasse. Aufgrund der Persistenz, Bioakkumulation in Nahrungsketten, Toxizität und der ubiquitären Verbreitung von PFAS zählen sie zu den „emerging pollutants“. Die PFAS-Analytik ist wegen ihrer vielfältigen physikalisch-chemischen Eigenschaften und der sehr hohen Anzahl an PFAS eine große Herausforderung. Da es für viele Anwendungen noch ungewiss ist, welche PFAS verwendet werden, wie sie in die Umwelt gelangen und welche Transformations- bzw. Abbauprodukte entstehen, stoßen analytische Ansätze, die nur auf Einzelsubstanzen abzielen, hier an ihre Grenzen. PFAS-Summenparameter-Methoden, die darauf abzielen ein möglichst vollständiges Abbild der PFAS-Belastungssituation widerzuspiegeln, werden daher immer wichtiger.
KW - PFAS
KW - HR-CS-GFMAS
KW - Fluorine
KW - SPM
KW - LC-MS/MS
KW - Schwebstoffe
PY - 2023
VL - 5
SP - 1
EP - 6
AN - OPUS4-57544
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - El-Athman, Rukeia
A1 - Bresch, Harald
A1 - Muth, Thilo
A1 - Rädler, Jörg
A1 - Rühle, Bastian
T1 - Datenmanagement im Nanomaterial-Labor: Einsatz von ELN-Software zur digitalen Transformation des Laboralltags
N2 - Angesichts der zunehmenden Digitalisierung und dem Einsatz datenintensiver Methodiken in der Wissenschaft stehen Forschende vor der Herausforderung, stetig wachsende Datenmengen nachvollziehbar zu dokumentieren, langfristig zu speichern und für Dritte nachnutzbar zu machen. Um diesen Anforderungen gerecht zu werden, bietet sich die Nutzung von Software-Lösungen an, welche Forschungsdatenmanagement mit der digitalen Dokumentation von Laborinventar und Experimenten in elektronischen Laborbüchern (engl. electronic lab notebooks (ELN)) verknüpfen.
KW - NanoPlattform
KW - BAM Data Store
KW - OpenBIS
KW - Forschungsdatenmanagement
KW - Research data management
KW - Elektronisches Laborbuch
KW - Electronic lab notebook (ELN)
PY - 2023
UR - https://analyticalscience.wiley.com/content/article-do/datenmanagement-im-nanomaterial-labor
SN - 0016-3538
IS - 9
SP - 24
EP - 26
PB - Wiley Analytical Science
CY - Weinheim
AN - OPUS4-59600
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Kornev, Roman
A1 - Gornushkin, Igor B.
A1 - Shabarova, Lubov
A1 - Kadomtseva, Alena
A1 - Mochalov, Georgy
A1 - Rekunov, Nikita
A1 - Romanov, Sergey
A1 - Medov, Vitaly
A1 - Belousova, Darya
A1 - Maleev, Nikita
T1 - Plasma-Chemical Disposal of Silicon and Germanium Tetrachlorides Waste by Hydrogen Reduction
N2 - The processes of hydrogen reduction of silicon and germanium chlorides under the conditions of high-frequency (40.68 MHz) counteracted arc discharge stabilized between two rod electrodes are investigated. The main gas-phase and solid products of plasma-chemical transformations are determined. Thermodynamic analysis of SiCl4 + H2 and GeCl4 + H2 systems for optimal process parameters was carried out. Using the example of hydrogen reduction of SiCl4 by the method of numerical modeling, gas-dynamic and thermal processes for this type of discharge are investigated. The impurity composition of gas-phase and solid reaction products is investigated. The possibility of single-stage production of high-purity Si and Ge mainly in the form of compact ingots, as well as high-purity chlorosilanes and trichlorogermane, is shown.
KW - High-frequency arc discharge
KW - Hydrogen reduction
KW - Silicon chlorides
KW - Germanium chlorides
PY - 2024
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-594454
DO - https://doi.org/10.3390/sci6010001
VL - 6
IS - 1
SP - 1
EP - 12
PB - MDPI AG
AN - OPUS4-59445
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Bilsel, M.
A1 - Gökçen, T.
A1 - Binici, B.
A1 - Isleyen, A.
A1 - Piechotta, Christian
A1 - Kar-wai, A.
A1 - Krylov, A.
A1 - Miheeva, A.
A1 - Beliakov, M.
A1 - Palagina, M.
A1 - chenko, Irina Tka
A1 - Perkola, N.
A1 - Lewin, M.
A1 - Hua, T.
T1 - High polarity analyte(s) in aqueous media: determination of L-PFOA and L-PFOS in ground water
N2 - The CCQM-K156 comparison was coordinated by TUBITAK UME on behalf of the Organic Analysis Working Group (OAWG) of the Comité Consultatif pour la Quantité de Matière (CCQM) for National Measurement Institutes (NMIs) and Designated Institutes (DIs) which provide measurement services in organic analysis under the 'Comité International des Poids et Mesures' Mutual Recognition Arrangement (CIPM MRA).
Perfluoro alkyl substances (PFAS) such as PFOS and PFOA have been used in numerous industrial applications and products. Because of their high stability and resistance to biodegradation, atmospheric photooxidation, direct photolysis and hydrolysis, they are extremely persistent in the environment. The European Union (EU) Water Framework Directive lists PFOS as a priority hazardous substance that poses a significant risk to the aquatic environment. The use of PFOS-containing Aqueous Film-Forming Foams (AFFFs) has been banned since June 2011 in the EU. As relatively water-soluble, effectively non-degradable compounds, PFOS and PFOA migrate to ground water. They are not removed in the conventional drinking water treatment, and therefore cause health risks in polluted areas. The EU Drinking Water Directive and the European Commission has proposed a limit value of 100 ng/L for the sum of 20 PFAS, including PFOS and PFOA.
This study provides the means for assessing measurement capabilities for determination of high polarity measurands in a procedure that requires extraction, clean-up, analytical separation and detection. Successful participation in CCQM-K156 demonstrates measurement capabilities in determining mass fraction of organic compounds, with a molecular mass of 200 g/mol to 700 g/mol, having high polarity pKow -2, in a mass fraction range from 0.5 ng/kg to 500 ng/kg in aqueous media.
Nine NMIs and DIs participated in the CCQM-K156 key comparison. Seven institutes reported their results. SPE was applied in the sample pre-treatment and LC-MS was applied for detection. All participating laboratories applied isotope dilution mass spectrometry (IDMS) techniques for quantification. Participants established the metrological traceability of their results using certified reference materials (CRMs) from NMIs with stated traceability; where commercially available high purity materials were used the purity was determined in-house. The CCQM-K156 results for L-PFOA and L-PFOS range from 2.75 ng/kg to 5.50 ng/kg with a % RSD of 19.5 % for L-PFOA and from 2.04 ng/kg to 4.45 ng/kg with a % RSD of 21.3 % for L-PFOS. The KCRV was assigned using a Hierarchical Bayesian Random Effects Model (HB REM) estimator from the values reported by six of the participants. One participant result of L-PFOS and one result of L-PFOA were excluded from the KCRV for technical reasons. The KCRV was 4.9 ng/kg ± 0.4 ng/kg for L-PFOA and 3.8 ng/kg ± 0.4 ng/kg for L-PFOS. The six institutes that were included in the assignment of consensus KCRV all agreed within their standard uncertainties.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
KW - PFAS
KW - Surface water
KW - ILC
KW - CCQM
PY - 2022
DO - https://doi.org/10.1088/0026-1394/59/1A/08016
VL - 59
IS - 1A
SP - 1
EP - 3
PB - IOP Publishing
AN - OPUS4-58941
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Steinhäuser, Lorin
A1 - Piechotta, Christian
A1 - Westphalen, Tanja
A1 - Kaminski, Katja
T1 - Evaluation, comparison and combination of molecularly imprinted polymer solid phase extraction and classical solid phase extraction for the preconcentration of endocrine disrupting chemicals from representative whole water samples
N2 - Estrogens are endocrine disrupting chemicals and of high concerns due to demonstrated harmful effects on the environment and low effect levels. For monitoring and risk assessment, several estrogens were included in the "watch list" of the EU Water Framework Directive which sets very low environmental quality standard (EQS) levels for Estrone (E1) and 17β-Estradiol (E2) of 0.4 ng L−1 and for 17α-Ethinylestradiol (EE2) of 0.035 ng L−1 requiring sensitive detection methods, as well as extensive sample preparation. A sensitive, derivatization-free, isotope dilution calibration HPLC-MS/MS method for a panel of 5 selected estrogens (including the 3 estrogens of the EU WFD watchlist), and a procedure for the reproducible preparation of a representative whole water matrix including mineral water, humic acids and solid particulate matter are presented. These are used in a diligent comparison of classical solid phase extraction (SPE) on hydrophilic-lipophilic balanced (HLB) phase to SPE on an estrogen-specific molecularly imprinted polymer phase (MISPE) for ultra-trace levels of the analytes (1–10 ng L−1). Additionally, a two-step procedure combining HLB SPE disks followed by MISPE is evaluated. The tow-step procedure provides superior enrichment, matrix removal and sample throughput while maintaining comparable recovery rates to simple cartridge SPE. Estimated method quantification limits (MQLs) range from 0.109–0.184 ng L−1 and thus meet EQS-levels for E1 and E2, but not EE2. The representative whole water matrix provides a reproducible comparison of sample preparation methods and lays the foundation for a certified reference material for estrogen analysis. The presented method will serve as the basis for an extended validation study to assess its use for estrogen monitoring in the environment.
KW - Estrogens
KW - Whole water samples
KW - Molecular imprinted polymers
KW - EU-WFD
PY - 2022
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-563547
DO - https://doi.org/10.1016/j.talo.2022.100163
SN - 2666-8319
VL - 6
SP - 1
EP - 5
PB - Elsevier B.V.
CY - Amsterdam, Niederlande
AN - OPUS4-56354
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Vo, P. H.N.
A1 - Vogel, Christian
A1 - Nguyen, H. T.M.
A1 - Hamilton, B. R.
A1 - Thai, P. K.
A1 - Roesch, Philipp
A1 - Simon, Franz-Georg
A1 - Mueller, J. F.
T1 - µ-X-ray fluorescence (XRF) and fluorine K-edge µ-X-ray absorption near-edge structure (XANES) spectroscopy for detection of PFAS distribution in the impacted concrete
N2 - An improved understanding of the distribution of per- and polyfluoroalkyl substances (PFAS) in PFAS-impacted concrete is important for risk management and decontamination of PFAS. This study incorporates µ-X-ray fluorescence (µ-XRF) and fluorine K-edge µ-X-ray absorption near-edge structure (µ-XANES) spectroscopy to gain non-destructive insights into PFAS distribution in the impacted concrete. The μ-XRF and μ-XANES spectroscopy provided additional details on the detection of PFAS, which were not detected by the desorption electrospray ionization (DESI) imaging method conducted previously. The shorter chain PFAS were found on the top part of the concrete core (0.5 cm), and longer chain PFAS were mostly at the bottom part of the concrete core (5 cm). The inorganic fluorine fraction was also detected, and it likely hampered the detection of organic fluorine such as PFAS in the concrete. Thus, this non-destructive technique is an complementary approach to detect PFAS in contaminated concrete.
KW - Beton
KW - Per- and Polyfluoroalkyl substances (PFAS)
KW - XANES spectroscopy
PY - 2024
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-616711
DO - https://doi.org/10.1016/j.hazl.2024.100134
SN - 2666-9110
VL - 5
SP - 1
EP - 5
PB - Elsevier B.V.
AN - OPUS4-61671
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Gauglitz, Günter
A1 - Bodensteiner, Michael
A1 - Bohleber, Pascal
A1 - Clases, David
A1 - Dahms, Marcel
A1 - Engelhard, Carsten
A1 - Haider, Markus
A1 - Hayen, Heiko
A1 - Herbst‐Irmer, Regine
A1 - Jäger, Martin
A1 - Kramell, Annemarie E.
A1 - Legner, Robin
A1 - Matysik, Frank‐Michael
A1 - Pöthig, Alexander
A1 - Rädle, Matthias
A1 - Seifert, Stephan
A1 - Steinhauser, Georg
A1 - Wolter, Kathrin
T1 - Trendbericht Analytische Chemie 2024
N2 - Mehrdimensionale Trenntechniken sowie Kopplungstechniken verbessern weiter die Auflösung in der Analytik. In der Elementanalytik beeindrucken neue Entwicklungen der Massenspektrometrie mit induktiv gekoppeltem Plasma, in der Archäometrie zerstörungsfreie In‐situ‐Analysen. Der 3‐D‐Druck treibt die elektroanalytische Forschung voran, und die Prozessanalytik setzt auf Lab‐on‐a‐Chip und vermeldet Neues bei der Raman‐Spektroskopie mit Flüssigkernlichtleitern.
KW - Analytische Chemie
KW - Trenntechniken
KW - Elementanalytik
KW - Massenspektrometrie
KW - Prozessanalytik
PY - 2024
DO - https://doi.org/10.1002/nadc.20244139242
SN - 1868-0054
VL - 72
IS - 4
SP - 52
EP - 64
PB - Wiley
CY - Weinheim
AN - OPUS4-62155
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Strangfeld, Christoph
A1 - Küttenbaum, Stefan
T1 - Zur Visualisierung von Schäden in Betonschwellen durch zerstörungsfreie Ultraschallprüfung
N2 - Die bildgebende Ultraschalltechnik liefert Hinweise auf verdeckte Schäden in Spannbetonschwellen. Dieses zerstörungsfreie Prüfverfahren schafft eine objektive und vergleichbare Basis für die Zustandsbestimmung der Schwellen und ermöglicht die Optimierung von baulichen Erhaltungsstrategien.
KW - Betonschwellen
KW - Ultraschall
KW - Schieneninfrastruktur
KW - Gleisoberbau
KW - Spannbetonschwelle
PY - 2023
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-591889
UR - https://www.eurailpress.de/etr
SN - 0013-2845
IS - 12
SP - 26
EP - 31
PB - DVV Media Group, Eurailpress
CY - Hamburg
AN - OPUS4-59188
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Weigel, Sandra
A1 - Sielaff, S.
A1 - Kunsic-Nowak, T.
A1 - Nytus, N.
A1 - Schwettmann, K.
A1 - Schulze, C.
A1 - Wetekam, J.
T1 - Die FTIR-Untersuchung von Bitumen: Chancen, Durchführung und Präzision
N2 - Die Fourier-Transformations-Infrarot-Spektroskopie (FTIR-Spektroskopie) stellt eine innovative und wirkungsvolle Methode zur Charakterisierung von Bitumen und bitumenhaltigen Bindemitteln dar. So erlaubt die FTIRCharakterisierung nicht nur eine Bewertung des Alterungsfortschritts eines Bindemittels, sondern zudem auch die Identifizierung von im Bitumen enthaltenen Additiven und Schadstoffen wie z. B. polyzyklischen aromatischen Kohlenwasserstoffen (PAK), die Ableitung verschiedener physikalischer und chemischer Kennwerte sowie weiterhin eine Klassifizierung von Bindemitteln nach verschiedenen übergeordneten Eigenschaften wie der Raffinerie, dem Alterungszustand und auch der Alterungsempfindlichkeit.
KW - Bitumen und bitumenhaltige Bindemittel
KW - FTIR-Spektroskopie
KW - Anwendungsmöglichkeiten
KW - Vergleichuntersuchung
KW - Arbeitsanleitung
KW - Präzision
PY - 2023
UR - https://www.kirschbaum.de/fachzeitschriften/strasse-und-autobahn/strasse-und-autobahn/aktuelles-heft-17.html
DO - https://doi.org/10.53184/STA8-2023-4
VL - 74/8
SP - 630
EP - 642
PB - KIRSCHBAUM VERLAG GmbH
CY - Bonn
AN - OPUS4-59049
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Quackatz, Lukas
A1 - Gornushkin, Igor B.
A1 - Griesche, Axel
A1 - Kannengießer, Thomas
A1 - Treutler, Kai
A1 - Wesling, Volker
T1 - In situ chemical analysis of duplex stainless steel weld by laser induced breakdown spectroscopy
N2 - The high corrosion resistance and good mechanical properties of duplex stainless steel (DSS) are due to its special chemical composition, which is a balanced phase ratio of ferrite (α) and austenite (γ). Many industrial applications require the integration of DSS components. For this, Gas tungsten arc welding (GTAW) is an excellent choice, as it allows an automated operation with high reproducibility. However, when the weld pool solidifies, critical ratios of α- and γ- phases can occur, which lead to solidification cracking, increased susceptibility to corrosion, and a decrease in ductility and critical strength. Previous studies have shown that these defects can be caused by the accumulation of manganese and chromium in the heat affected zone (HAZ), requiring ongoing monitoring of this accumulation. A suitable method for such monitoring is laser-induced breakdown spectroscopy (LIBS), which can be used in two operating modes: calibration using standard reference samples and calibration-free. Unlike conventional quantitative LIBS measurements, which require reference samples to generate a calibration curve, calibration-free LIBS (CF-LIBS) allows chemical compositions to be determined solely from the emission spectrum of the plasma. Numerous publications show that CF-LIBS is a fast and efficient analytical method for the quantitative analysis of metal samples. In this work, CF-LIBS is applied to spectra obtained during GTAW DSS welding and the result is compared with those obtained by PLS analysis. A good correlation was found between both types of analysis, demonstrating the suitability of the CF-LIBS method for this application. The CF-LIBS method has a significant advantage over conventional LIBS due to the rapid in situ measurement of concentrations of major alloying elements without calibration procedure. This, combined with fast feedback and appropriate adjustment of welding parameters, helps prevent welding defects.
KW - Duplex stainless steels
KW - In situ measurement
KW - LIBS
KW - GMAW
PY - 2024
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-597940
DO - https://doi.org/10.1016/j.sab.2024.106899
SN - 0584-8547
VL - 214
SP - 1
EP - 7
PB - Elsevier B.V.
AN - OPUS4-59794
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Rabin, Ira
A1 - Gordon, Nehemia
A1 - Calvillo, Nelson
T1 - Coloured Ruling Lines in a Fourteenth-Century Ashkenazi Torah Scroll
N2 - Rabbinic halakhah required that Torah scrolls be written with relief ruling, horizontal and vertical lines scored into the writing surface. Coloured ruling with plummet or ink would make a Torah scroll invalid for liturgical use. Ruling lines on some leather fragments of early Oriental Torah scrolls give the impression of being produced with plummet or ink but may be the result of dust in the furrows of relief ruling. Erfurt 9, a fourteenth-century Ashkenazi Torah scroll, has coloured ruling, which is partial secondary re-ruling, on 13 of the 34 surviving sheets, perhaps added when the original relief ruling was difficult to see. The coloured ruling in Erfurt 9 is brown, giving it the visual appearance of iron-gall ink. However, XRF tests showed that the only meaningful metallic component in the coloured ruling was lead (Pb). Lead plummet ruling tends to have a greyish appearance. Black specks under near infrared light are consistent with minium, a lead-based red ink that can turn brown when it degrades. Partial secondary re-ruling added with minium to the original relief ruling comes as a surprise as it would have rendered Erfurt 9 unfit for liturgical use.
KW - Hebrew Manuscripts
KW - Ruling Lines
KW - Coloured Ink
PY - 2024
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-628531
DO - https://doi.org/10.25592/uhhfdm.17169
SN - 2410-0951
VL - 10
SP - 9
EP - 32
AN - OPUS4-62853
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - El-Athman, Rukeia
A1 - Rädler, Jörg
A1 - Löhmann, Oliver
A1 - Ariza de Schellenberger, Angela
A1 - Muth, Thilo
T1 - The BAM Data Store
N2 - As a partner in several NFDI consortia, the Bundesanstalt für Materialforschung und -prüfung (BAM, German federal institute for materials science and testing) contributes to research data standardization efforts in various domains of materials science and engineering (MSE). To implement a central research data management (RDM) infrastructure that meets the requirements of MSE groups at BAM, we initiated the Data Store pilot project in 2021. The resulting infrastructure should enable researchers to digitally document research processes and store related data in a standardized and interoperable manner. As a software solution, we chose openBIS, an open-source framework that is increasingly being used for RDM in MSE communities.
The pilot project was conducted for one year with five research groups across different organizational units and MSE disciplines. The main results are presented for the use case “nanoPlattform”. The group registered experimental steps and linked associated instruments and chemicals in the Data Store to ensure full traceability of data related to the synthesis of ~400 nanomaterials. The system also supported researchers in implementing RDM practices in their workflows, e.g., by automating data import and documentation and by integrating infrastructure for data analysis.
Based on the promising results of the pilot phase, we will roll out the Data Store as the central RDM infrastructure of BAM starting in 2023. We further aim to develop openBIS plugins, metadata standards, and RDM workflows to contribute to the openBIS community and to foster RDM in MSE.
T2 - 1st Conference on Research Data Infrastructure
DA - 12.09.2023
KW - Research Data Infrastructure
KW - Electronic Lab Notebook (ELN)
KW - openBIS
KW - Research Data Management
PY - 2023
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-596032
DO - https://doi.org/10.52825/CoRDI.v1i.229
VL - 1
SP - 1
EP - 5
AN - OPUS4-59603
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Meyer, Klas
T1 - Flexible Prozessanalytik für die pharmazeutische Produktion - Benchtop-NMR-Spektroskopie im industriellen Einsatz
N2 - Im Rahmen des EU-Projekts „CONSENS – Integrated Control and Sensing“ wurde ein vollautomatisiertes, gemäß Atmosphère-Explosibles(ATEX)-Regeln zertifiziertes Analysatormodul auf Basis eines kommerziellen Benchtop-Kernspinresonanzspektrometers (Engl. nuclear magnetic resonance, NMR) entwickelt und im Umfeld einer modularen containerbasierten Produktionsanlage validiert. Auf Basis der gewonnenen Daten konnten sowohl eine iterative Optimierung der Prozessparameter erfolgen als auch Referenzdaten für die Kalibrierung eines Nahinfrarot-Spektrometers gewonnen werden.
KW - Prozessanalytik
KW - NMR-Spektroskopie
KW - Modulare Produktion
KW - Kalibriertransfer
PY - 2022
VL - 12
IS - 3
SP - 122
EP - 129
PB - Editio Cantor Verlag
CY - Aulendorf
AN - OPUS4-55402
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Maiwald, Michael
T1 - Metrologie für fortschrittliche Wasserstoffspeicherlösungen – Das EU-Projekt MefHySto
T1 - Metrology for advanced hydrogen storage solutions – The EU project MefHySto
N2 - Das europäische Projekt MefHySto befasst sich mit dem Bedarf an großmaßstäblichen Energiespeichern, die für eine Umstellung der Energieversorgung auf erneuerbare Energien erforderlich sind. Eine solche Speicherung ist entscheidend, um Energie zu Spitzenzeiten zu liefern, wenn die erneuerbaren Energiequellen schwanken. Eine mögliche Lösung für die Energiespeicherung ist der großtechnische Einsatz von Wasserstoff. Die messtechnische Rückführbarkeit in der Energieinfrastruktur für die Wasserstoffspeicherung ist dann von entscheidender Bedeutung und eine bessere Kenntnis der chemischen und physikalischen Eigenschaften von Wasserstoff sowie rückführbare Messungen und validierte Techniken unverzichtbar.
N2 - The European project MefHySto addresses the need of large-scale energy storage, which is required for a shift to renewable energy supply. Such storage is mandatory to supply energy at peak times when renewable sources fluctuate. A possible solution for energy storage is large-scale use of hydrogen. Metrological traceability in the energy infrastructure for hydrogen storage is then crucial and a better knowledge of the chemical and physical properties of hydrogen as well as traceable measurements and validated techniques are indispensable.
KW - Wasserstoff
KW - Wasserstoffspeicher
KW - Infrastruktur
KW - Metrologie
KW - PEM-Wasserelektrolyse
KW - Rückverstromung
KW - Lastwechsel
KW - Wasserstoff-Qualität
PY - 2022
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-556451
UR - https://gwf-gas.de/forschung-entwicklung/metrologie-fuer-fortschrittliche-wasserstoffspeicherloesungen-das-eu-projekt-mefhysto/
SN - 2366-9594
VL - 163
IS - 9
SP - 38
EP - 45
PB - Vulkan Verlag
CY - Essen
AN - OPUS4-55645
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Jakubowski, N.
A1 - Borrmann, S.
A1 - Recknagel, Sebastian
A1 - Roik, Janina
A1 - Rickert, F.
T1 - Comparison of peristaltic pumps used for sample introduction in Inductively Coupled Plasma-Atomic Emission Spectroscopy (ICP-AES)
N2 - In this investigation, two conventional peristaltic pumps are compared with a new pump based on the “easy click” principle using a simultaneous ICP-AES instrument with standard operating conditions. It is found that the figures of merit achieved are quite comparable for all three pumps. Relative standard deviations (RSDs) range between 0.2% and 1.8%, and limits of detection as low as 0.1 μg/L have been achieved , demonstrating that the easy click principle of the new pump does not compromise the analytical figures of merit.
KW - ICP-AES
KW - Peristaltic pumps
KW - ICP-MS
PY - 2020
IS - 35 / S4
SP - 6
AN - OPUS4-52020
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Recknagel, Sebastian
T1 - Analytische Chemie Gusseisen, Gummi, Bodenproben
N2 - Die BAM stellt seit über 100 Jahren Referenzmaterialien (RM) her. Seit damals haben sich die Anforderungen an RM stark verändert. Der Artikel gibt einen Einblick in Anforderungen und die Herstellungsweise von Referenzmaterialien.
KW - Referenzmaterialien
KW - ISO-Guide 35
KW - Boden
PY - 2021
SP - 51
EP - 53
AN - OPUS4-53695
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Meyer, Klas
T1 - Atomkerne zählen - Quantitative NMR-Spektroskopie als vielseitige Methode in Labor und Prozess
N2 - Meist präsentieren sich Laboratorien für NMR-Spektroskopie auf den ersten Blick von außen nur wenig einladend. Es lohnt sich aber einen Blick hinein zu riskieren, denn die Methode ist heute unverzichtbar für die analytische Chemie. Die quantitativen Möglichkeiten werden häufig unterschätzt, erfahren allerdings durch den aufstrebenden Markt kompakter Benchtop-NMR-Spektrometer verstärktes Interesse für Anwendungen von der Laborbank bis hin zum Industrieprozess.
KW - NMR-Spektroskopie
KW - Benchtop-NMR
KW - qNMR
PY - 2020
UR - https://analyticalscience.wiley.com/do/10.1002/was.000600052
SN - 0016-3538
VL - 64
IS - 10
SP - 28
EP - 30
PB - Wiley-VCH GmbH
CY - Weinheim
AN - OPUS4-51464
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Gordon, Nehemia
A1 - Patrick, Andrist
A1 - Hahn, Oliver
A1 - Vasileiadis, Pavlos D.
A1 - Calvillo, Nelson
A1 - Rabin, Ira
T1 - Did the Original Scribes Write the Distigmai in Codex Vaticanus B of the Bible (Vat. gr. 1209)?
N2 - The fourth-century Greek Bible manuscript Codex Vaticanus B (Vat. gr. 1209) contains pairs of horizontally aligned marginal dots known as distigmai, which correspond to textual variants in other manuscripts. The production of the distigmai has been variously dated to the 4th or 16th centuries. A fourth-century date would prove the early existence of hundreds of textual variants, many of which are otherwise only witnessed by later manuscripts. Near infrared microscope reflectography combined with micro-X-ray fluorescence spectroscopy proved that the distigmai, both those categorized as “apricot” (which are visually similar to the ink of the original main text) and “chocolate” (which are visually similar to the reinking of the main text) were written with ink(s) made from chemically purified vitriol, a process that only became standard in the 16th century. As a result, there is no reasonable chance that the distigmai were written in the fourth century. Horizontal lines that have been hypothesized to function as text-critical obeloi were written in the same ink as the original main text, which differs completely from that of the distigmai. In other words, the distigmai and horizontal lines tested were not produced during the same writing session and are separated by more than 1,000 years, making it impossible for them to have functioned as conjoining text-critical symbols in the 4th century.
KW - Bible manuscripts
KW - New Testament
KW - Paratextual features
KW - Textual criticism
KW - Obelos
KW - Septuagint
KW - XRF
KW - Greek palaeography
PY - 2024
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-622902
DO - https://doi.org/10.1163/27728641-00302005
SN - 2772-8633
VL - 3
IS - 2
SP - 125
EP - 156
PB - Brill
CY - Leiden
AN - OPUS4-62290
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Cohen, Z.
A1 - Hennings, T.
A1 - Hahn, Oliver
A1 - Depreux, P.
A1 - Rabin, Ira
T1 - Black inks under examination. Part 2: a case study of Carolingian manuscripts
N2 - With this paper, we would like to contribute to the study of black writing materials by investigating the black inks used in the manuscripts from monastic production in the eastern part of the Frankish kingdom, especially in the region of Lake Constance and in Bavaria and dated to the period between the 8th and the 10th centuries. The corpus under study contains manuscripts with formulae, i.e. model letters and charters, besides numerous other types of texts with no clear separation between them (for example by titles).
Sixty-three manuscripts have been studied with the aim of reconstructing the history of both their copying and their use. To this aim, we adopted a non-invasive approach that included near-infrared imaging and X-ray fluorescence spectroscopy for on-site measurements, supported by historical and palaeographic analysis. The results obtained in this project are compared with several other archaeometric studies of contemporary manuscripts with the general aim of understanding the use of black ink in medieval manuscripts.
KW - Manuscript
KW - Ink analysis
KW - Carolingian
PY - 2023
DO - https://doi.org/10.4000/techne.18919
SN - 2239-0243
VL - 56
SP - 105
EP - 113
AN - OPUS4-61582
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Rabin, Ira
A1 - Gordon, Nehemia
A1 - Cohen, Zina
T1 - Inks of the Bologna Scroll: A Preliminary Study
N2 - Rotolo 2 at the Biblioteca Universitaria di Bologna, also known simply as the “Bologna Scroll,” is currently the oldest known complete Torah scroll without later replacement sheets or significant lacunae. The Bologna Scroll has some unusual scribal features. According to one opinion in the Babylonian Talmud, a Torah scroll must be written with carbon ink to be valid for liturgical use.12 The main inks of the Bologna Scroll are very black, and the inks of the marginal corrections in tiny letters are even blacker. In this study, eh inks were tested by means of XRF-spectroscopy and NIR imaging. Conreary to the expectations, the current tests have definitively determined that the Bologna Scroll was both written and corrected using multiple iron-gall inks.
KW - Torah
KW - Ink
KW - Historic ink
PY - 2024
DO - https://doi.org/10.1353/mns.2024.a945374
VL - 9
IS - 2
SP - 222
EP - 242
AN - OPUS4-62264
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Rabin, Ira
A1 - Krutzsch,
A1 - Nehring,
ED - Prignitz, Sebastian
ED - Vaelske, Veit
T1 - Der Papyruskodex Berlin P 1862: Restaurierung und materialtechnische Beobachtungen
N2 - This paper presents the conservation of the codex Berlin P 1862, which includes the reconstruction of the original double leaves. This made it possible to reconstruct the original sequence of the layers of the codex. In addition to a detailed description of the papyrus material, technical details are explained. These concern the production, structure and layout of this codex.
KW - Papyrus
KW - Tusche
PY - 2024
DO - https://doi.org/10.1515/9783111345253-011
SP - 141
EP - 163
AN - OPUS4-62265
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Li, X.Q.
A1 - Li, H.M.
A1 - Jiao, H.
A1 - Guo, Z.H.
A1 - Zhang, Q.H.
A1 - Kneeteman, L.E.
A1 - Lewin, M.
A1 - Pires do Rego, E.C.
A1 - Leal, R.V.
A1 - Violante, F.G.M.
A1 - Riedel, Juliane
A1 - Koch, Matthias
T1 - CCQM Key Comparison track A CCQM-K168: Non-polar analytes in high carbohydrate food matrix: trans-zearalenone in maize powder
N2 - Demonstrating competency and equivalence for the measurement capacity of contaminants and nutrients in primary foodstuffs is a priority of the OAWG 10-year strategy for Track A core comparisons. Such measurements have posed significant challenges for reference material producers and calibration service providers. This key comparison (KC), under the topic of “non- polar analyte in high carbohydrate food matrix: trans-Zearalenone (trans-ZEN) in maize powder” , was a sector of the model system selected to align with this class within the OAWG strategy. Evidence of successful participation in formal, relevant international comparisons is needed to demonstrate the Calibration and Measurement Capabilities (CMCs) of national metrology institutes (NMIs) and designated institutes (DIs).
17 NMIs and DIs participated in the Track A KC CCQM- 168 “non-polar analyte in high carbohydrate food matrix: trans-ZEN in maize powder” . Participants were requested to evaluate the mass fraction (μg/kg) of trans-ZEN in maize powder material. Methods like liquid-liquid extraction and SPE were applied in the pre-treatment, and HPLC-MS/MS and HPLC-FLD were used for detection by the participants. The mass fractions for trans-ZEN were in the range of (91.8 to 169) μg/kg with standard uncertainties of (1.5 to 24.7) μg/kg, and corresponding relative standard uncertainties from 1.5% to 14.6%. Two labs, INTI and BAM were excluded from the KCRV evaluation. INTI result was identified as an outlier and confirmed their method had insufficient specificity. For BAM the calibration approach they used does not meet the CIPM traceability requirements. The other 15 labs included in the calculation of the consensus KCRV all agreed within their standard uncertainties. Hierarchical Bayes was used as estimators in calculating KCRV and standard uncertainty.
Successful participation in CCQM-K168 demonstrates the measurement capabilities in determining mass fraction of organic compounds, with molecular mass of 100 g/mol to 500 g/mol, having low polarity pKow < -2, in mass fraction range from 1 μg/kg to 1000 μg/kg in a high carbohydrate food matrix.
KW - Metrology
KW - Quality Assurance
KW - Mycotoxin Analysis
KW - Sustainable Food Safety
PY - 2023
DO - https://doi.org/10.1088/0026-1394/60/1A/08021
VL - 60
IS - 1a
SP - 08021
AN - OPUS4-59059
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Dalichow, Dirk
A1 - Blaschke, Jil
A1 - Wilsch, Gerd
A1 - Völker, Tobias
T1 - Revolutionizing Concrete Analysis and Maintenance with Laser-Induced Breakdown Spectroscopy
N2 - Laser-induced breakdown spectroscopy (LIBS) is a valuable complement to established methods for the chemical analysis of concrete. Compared to conventional techniques, LIBS enables spatially resolved imaging of harmful ion distributions within the cementitious matrix. It allows the simultaneous detection of all relevant ions and degradation mechanisms, facilitating a better understanding of interacting processes. The benefits of multi-element analysis are illustrated through selected examples that highlight the method’s superior information content. Ion penetration profiles are recorded at a resolution of 0.25 mm, providing high-quality input data for service life modelling. Instead of drill dust, a 50 mm core sample is used. The measurement is automated, requires no chemical reagents or elaborate sample preparation, and is completed within minutes.
KW - LIBS
KW - Durability
KW - Ion transport profiling
KW - Concrete analysis
KW - Service life assessment
PY - 2025
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-642846
DO - https://doi.org/10.58286/31656
SN - 1435-4934
VL - 30
IS - 10
SP - 1
EP - 8
PB - NDT.net GmbH & Co. KG
AN - OPUS4-64284
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Noureen, N.
A1 - Shah, F. A.
A1 - Lisec, Jan
A1 - Usman, H.
A1 - Khalid, M.
A1 - Munir, R.
A1 - Zaidi, N.
T1 - Revisiting the Association between Human Leukocyte Antigen and End-Stage Renal Disease
N2 - Multiple works have studied possible associations between human leukocyte antigen (HLA) alleles and end stage renal disease (ESRD). However, there are several contradictions in these previous works and no consistent HLA associations with ESRD itself have been identified. Most of these works have several limitations, for instance, the population size was too small, or only limited HLA loci were studied. The presented work aims to revisit the association between ESRD and HLA antigens while taking in to account the previously overlooked limitations. Here, we compared the HLA polymorphism (at HLA-A, -B, -C, -DRB1, -DQB1 and DQA1 loci) in ESRD patients (n=497) and controls (n=672). Our data identified several HLA alleles that displayed a significant positive or negative association with ESRD. We also determined whether heterozygosity or homozygosity of the ESRD-associated HLA alleles at different loci could modify the prevalence of the disease. Few HLA allele combinations displayed significant associations with ESRD among which HLA-A*3 –HLA-A*26 combination showed the highest strength of association (OR= 4.488, P≤ 0.05) with ESRD. However, the age of ESRD onset was not affected by HLA allele combinations at different loci. Most of the previous works have studied the association of HLA with ESRD in homogeneous ethnic groups and have interpreted their data accordingly. Here, we also performed an extensive literature analysis to determine whether the association of HLA to ESRD can be similar across different ethnic groups. This analysis showed that at least for certain alleles, the association of HLA to ESRD can be similar in different ethnic groups. For instance, HLA-A*11, HLA-DRB1*11, and HLA-DRB1*4 all showed significant positive associations with ESRD in different ethnic groups. The findings of our study will help in determining possible protective or susceptible roles of various HLA alleles in ESRD.
KW - Mass-Spectrometry
KW - HLA
KW - Renal disease
PY - 2020
DO - https://doi.org/10.1101/2020.03.18.996330
SP - 1
EP - 23
AN - OPUS4-50720
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Rabin, Ira
ED - Binder, J.
T1 - The marginal notes of Tosefta MS Erfurt
N2 - Manuscript Erfurt 12 of the Tosefta (now Berlin, Staatsbibliothek, Ms. or. fol. 1220) is one of three major textual witnesses of the Tosefta. This manuscript has over 80 marginal notes which have not merited scholarly attention. This article presents a comprehensive analysis of all the marginal notes, including an evaluation of their ink composition, a palaeographic assessment of the scripts, as well as a philological assessment of their contents. Combining these methodologies differentiates between the glosses of the scribe and those added by later hands and identifies their provenance, allowing us to trace the history of the manuscript via the emendations that took place in the scholarly communities in which the manuscript was studied. One of the important outcomes of the research is an early dating of the manuscript to eleventh-century Italy, overturning the scholarly view which dates the manuscript to twelfth-century Rhineland
KW - Hebrew Manuscripts
KW - Ink
KW - NIR
KW - XRF
PY - 2025
DO - https://doi.org/10.3828/jjs.2025.76.2.272
SN - 0022-2097
VL - 76
IS - 2
SP - 272
EP - 300
AN - OPUS4-64770
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Meermann, Björn
A1 - Lisec, Jan
A1 - Jaeger, Carsten
A1 - Saatz, Jessica
A1 - Traub, Heike
A1 - von der Au, Marcus
T1 - Mehr Analyten, kleinere Proben
N2 - Molekülmassenspektrometrie entwickelt sich weg von klassischer Target- hin zu Nontarget-Analytik. Elementmassenspektrometrie liefert hohe Ortsauflösung beim Element-Imaging und analysiert einzelne Zellen. Aufgrund der Fortschritte bei den Geräten für Timeof-Flight-Massenspektrometrie mit induktiv gekoppeltem Plasma (ICPToF-MS) lässt sich das gesamte Periodensystem der Elemente in kurzen transienten Signalen quasi-simultan massenspektrometrisch erfassen.
KW - Massenspektrometrie
KW - Non-target
KW - ICP-ToF-MS
KW - Laser Ablation/Imaging
PY - 2021
VL - 69
IS - Juni
SP - 64
EP - 67
PB - Wiley-VCH
AN - OPUS4-52800
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Ukrainczyk, Neven
A1 - Bernard, Thomas
A1 - Babaahmadi, Arezou
A1 - Huang, Liming
A1 - Zausinger, Christoph
A1 - Soive, Anthony
A1 - Bonnet, Stéphanie
A1 - Georget, Fabien
A1 - Mrak, Maruša
A1 - Dolenec, Sabina
A1 - Völker, Tobias
A1 - Suraneni, Prannoy
A1 - Wilson, William
T1 - Test methods for chloride diffusivity of blended cement pastes: a review by RILEM TC 298-EBD
N2 - The use of supplementary cementitious materials (SCM) is an important part of the roadmap for reducing CO2 emissions and extending the service life of reinforced concrete structures. To accelerate the adoption of SCMs, the RILEM Technical Committee 298-EBD evaluates scaled-down cement paste test methods to assess the effect of SCM on resistance to chloride and sulfate ingress and reactivity, which are critical to concrete durability. This review focuses on methods for measuring chloride diffusivity and is divided into four sections: diffusivity models and parameters, diffusion test methods (including NMR and chloride measurements), migration test methods and implications for future research. Key insights highlight the complexities of multi-species ionic and molecular diffusion/migration, including various binding interactions, and compares the different measurement methodologies. The review also addresses the test scale and aggregate effects, noting the pros and cons of testing at the paste, mortar, and concrete scales. The review underscores the need for further investigation into testing protocols and the influence of SCM on chloride diffusion, emphasizing that comprehensive testing across different scales provides complementary information for assessing durability performance.
KW - Chloride ingress
KW - Diffusion tests
KW - Migration test
KW - Cement paste
KW - Concrete
KW - Supplementary cementitious materials (SCM)
PY - 2025
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-645889
DO - https://doi.org/10.1617/s11527-025-02809-4
SN - 1359-5997
VL - 58
IS - 10
SP - 1
EP - 35
PB - Springer Science and Business Media LLC
AN - OPUS4-64588
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Teutenberg, Thorsten
A1 - Blöth, Anton
A1 - Bolling, Janina
A1 - Kuch, Susanne
A1 - Meyer, Lena
A1 - Rösch, Richard
T1 - Auf dem Weg in die digitale Transformation
N2 - Die Digitalisierung in der Laborbranche stellt eine komplexe Herausforderung dar – nicht zuletzt aufgrund zahlreicher Einzelprojekte und vieler proprietärer Insellösungen. Um eine konsequente und wirkungsvolle Labordigitalisierung und Prozessautomatisierung zu erreichen, braucht es eine übergreifende Sichtbarkeit und Vernetzung bestehender Initiativen. Diese Notwendigkeit haben verschiedene Akteure der Laborbranche erkannt und, angestoßen durch die Initiative QI-Digital, den Digital LabHub ins Leben gerufen. Ziel ist es, eine Plattform für Wissensaustausch und -transfer, gegenseitige Unterstützung und praxisnahe Umsetzung zu schaffen – offen für Labore aller Branchen und Anwendungsfelder. Der Digital LabHub soll gezielte Hilfestellung beim Einstieg in die Digitalisierung bieten, Labore zukunftssicher aufstellen und dabei helfen, regulatorische Anforderungen zu erfüllen.
KW - Digitale Transformation
KW - Digitalisierung
KW - Kalibrierlabor
KW - Prüflabor
KW - QI-Digital
KW - Qualitätsinfrastruktur
PY - 2025
UR - https://analyticalscience.wiley.com/content/article-do/auf-dem-weg-die-digitale-transformation
SP - 1
EP - 3
PB - Wiley Analytical Science
CY - Weinheim
AN - OPUS4-64482
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Dorgerloh, Ute
A1 - Gökçe, Emine
A1 - Freeling, Finnian
T1 - Monitoring von Trifluoressigsäure (TFA) im Wasser: Neue DIN-Norm bringt Klarheit bei der Analytik
N2 - Um eine zuverlässige und vergleichbare Messung von TFA in verschiedenen Wasserarten zu ermöglichen, wurde im DIN-Normenausschuss Wasserwesen (NAW) ein standardisiertes analytisches Verfahren entwickelt. Der im Dezember 2024 veröffentlichte Normentwurf DIN 38407-53 beschreibt ein LC-MS/MS-Verfahren zur Bestimmung von TFA mittels Direktinjektion. Die Norm adressiert den wachsenden Bedarf an einheitlichen Messstandards im Umweltmonitoring – mit Potenzial für den Einsatz in Überwachungsprogrammen, Laboratorien und Fachbehörden.
KW - Trifluoressigsäure TFA
KW - Validierungsringversuch
PY - 2025
IS - 07
SP - 94
EP - 97
PB - DIN
AN - OPUS4-64537
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Steinbeck, Christoph
A1 - Jung, Nicole
A1 - Bach, Felix
A1 - Neumann, Steffen
A1 - Herres-Pawlis, Sonja
A1 - Liermann, Johannes
A1 - Koepler, Oliver
A1 - Bannwarth, Christoph
A1 - Bender, Theo
A1 - Bocklitz, Thomas
A1 - Boehm, Franziska
A1 - Bonatto Minella, Christian
A1 - Biedermann, Frank
A1 - Brack, Werner
A1 - Cunha, Ricardo
A1 - Czodrowski, Paul
A1 - Eberl, Franziska
A1 - Engel, Thomas
A1 - Engstfeld, Albert
A1 - Fischer, Tillmann G.
A1 - Friedrich, Pascal
A1 - Glorious, Frank
A1 - Golub, Benjamin
A1 - Grathwol, Christoph
A1 - Haag, Rainer
A1 - Hunold, Johannes
A1 - Jacob, Christoph
A1 - Johannsen, Jochen
A1 - Jollife, John
A1 - Kast, Stefan
A1 - Kettner, Carsten
A1 - Kuhn, Stefan
A1 - Lanza, Giacomo
A1 - Lisec, Jan
A1 - Manolikakes, Georg
A1 - Mata, Ricardo
A1 - Meiler, Jens
A1 - Müller, Matthias
A1 - Müller-Pfefferkorn, Ralph
A1 - Ortmeyer, Jochen
A1 - Patterson, Wendy
A1 - Pleiss, Jürgen
A1 - Riedel, Annalisa
A1 - Riedel, Jens
A1 - Schatzschneider, Ulrich
A1 - Schuster, Leonie
A1 - Seeberger, Peter
A1 - Seibert, Johann-Nikolaus
A1 - Stadler, Peter
A1 - Zeitler, Kirsten
T1 - Proposal NFDI4Chem 2025-2030 In the National Research Data Infrastructure (NFDI) — Our Vision: All Chemists Publish FAIR Data
N2 - The first funding period of NFDI4Chem established a robust foundation for research data management (RDM) in chemistry by promoting FAIR data principles and creating a cohesive infrastructure to capture well-annotated data early in the lab through electronic lab notebooks (ELNs) and making this data available in public repositories. Key achievements include standardised data formats and metadata, a federated repository environment, and improved data visibility and accessibility. Training programs and outreach have significantly increased awareness and adoption of best RDM practices. In the second funding period, the consortium aims to advance these achievements by consolidating this infrastructure, developing a model for its sustainable maintenance and operation, and fostering cultural change for its widespread adoption. Goals include ensuring seamless data workflows from laboratories to open repositories, enhancing interoperability, and supporting innovative research through AI-ready data. The work plan is organised into six task areas (TAs). TA1 (Management) provides leadership and supports all other TAs in achieving their objectives. TA2 (Smart Lab) aims to develop a fully digital research environment, including an ELN as a modular platform. This environment will support data collection, management, storage, analysis, and sharing. Integrating devices and external resources will enable seamless data transfer to repositories. TA3 (Repositories) will consolidate the repository ecosystem. The goal is to integrate repositories into a federated system for better accessibility and interoperability, ensuring long-term data availability and sustainability. TA4 (Metadata, Data Standards, and Publication Standards) focuses on developing and promoting new data and metadata standards in an international community process. This includes applying ontologies to create a semantic foundation for linking research data, making it machine-readable and enabling knowledge graphs. TA5 (Community and Training) is dedicated to fostering a cultural shift towards digital chemistry through continuous engagement, collecting requirements, and providing extensive training and support through workshops and open education resources. It will promote FAIR-compliant machine learning applications, embedding RDM into academic curricula to ensure future scientists are well-versed in these practices. TA6 (Synergies and Cross-Cutting Topics) aims to enhance collaboration across NFDI consortia and beyond. This includes developing ontologies, terminology services, the search service, and other cross-cutting solutions, integrating these developments into existing infrastructure, enabling interdisciplinary data harmonisation and fostering machine learning applications.
KW - Research Data Management
KW - FAIR
KW - Chemistry
PY - 2025
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-648540
DO - https://doi.org/10.3897/rio.11.e177037
SN - 2367-7163
VL - 11
SP - 1
EP - 100
PB - Pensoft Publishers
AN - OPUS4-64854
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Vogel, Christian
A1 - Urban, Klaus
A1 - Ackerhans, C.
A1 - Gorbushina, Anna
T1 - Analysis of Carbon and Nitrogen from Atmospheric Sources by Bulk Deposition Sampling at various locations in Germany
N2 - Atmospheric deposition of particulate matter is an important indicator of air pollution and a significant factor in material surface fouling. The elemental composition of this nutrient-containing dust depends largely on the exposure region and time as well as on climate. Therefore, in this paper we report an analysis of atmospheric pollutions with a self-made low-cost bulk deposition sampler directed at sampling deposition via air transport and rainfall. We used the device in diverse environments - thus comparing an urban region, an area surrounded by forest and an area mainly dominated by agriculture. The total organic carbon (TOC) and total nitrogen (TN) amounts were selected as indicator parameters and analyzed in a biweekly rhythm for three and a half and two years, respectively. The TOC value responded to particulate matter in the urban area, especially significant were the influences of the New Year's firework in urban and pollen in the rural forest area. In contrast, the TN value was more under the influence of the nitrogen emissions in the agriculture-dominated area. However, the TN value did not correlate with the NOx values in the urban area because the atmospheric nitrogen emissions in the city might originate from various emission sources. Summarizing, the TOC and TN values of the self-made low-cost bulk deposition sampler were in good agreement with environmental events of their immediate surrounding. Moreover, the selected containers and sampling procedures are universally applicable to monitor and analyze organic as well as inorganic parameters (e.g. metal ions) of atmospheric deposition.
KW - Passive sampling
KW - Biomonitoring
KW - Air Analysis
PY - 2024
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-609373
DO - https://doi.org/10.1016/j.envadv.2024.100583
SN - 2666-7657
VL - 17
SP - 1
EP - 9
PB - Elsevier Ltd.
AN - OPUS4-60937
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Meyer, Andreas
A1 - Weidner, Steffen
A1 - Kricheldorf, Hans R.
T1 - Star-shaped poly(l-lactide)s based on pentaerythritol: About crystallization and polycondensation plus disproportionation and ring formation in the solid state
N2 - Star-shaped poly( L-lactide)s (s-PLAs), were prepared by ring-opening polymerization of with pentaerythritol and catalyzed by tin(II) 2-ethylhyexanoate (SnOct out in bulk at either 120 ◦ C or 160 ◦ L-lactide (LA) initiated 2 ). Two small series of ROPs were carried C with variation of the LA/initiator ratio. Matrix-assisted laser desorption/ ionization time-of-flight (MALDI-TOF) mass spectra revealed traces of cycles in 120 ◦ C samples only at low initiator/catalyst ratios. In contrast, higher fractions of cycles were detected in samples prepared at 160 C, suggesting a "back-biting" origin. The influence of arm length and thermal history on crystallinity was investigated by differential scanning calorimetry (DSC) and wide-angle x-ray scattering (WAXS). It was shown that annealing increased the melting temperature (T ◦ ◦ m ) and crystallinity. However, annealing at 140 ◦ C for 14 d also caused significant solid-state transesterification. In addition, crystallites composed of s-PLAs with extended arms and, simultaneously, crystallites composed exclusively of extended rings were formed, identified by their typical "sawtooth" pattern in the MALDI mass spectra. Small angle x-ray scattering (SAXS) indicated that the crystal thickness was lower than that of linear PLAs annealed under identical conditions, but increased upon annealing at 140 C.
KW - MALDI-TOF MS
KW - Polylactide
KW - Crystallisation
KW - AStar-shaped polymers
PY - 2025
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-636832
DO - https://doi.org/10.1016/j.polymer.2025.128709
SN - 0032-3861
VL - 334
SP - 1
EP - 11
PB - Elsevier Ltd.
AN - OPUS4-63683
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Rösler, Alexander
A1 - Weidner, Steffen
A1 - Klamroth, Tillmann
A1 - Müller, Axel HE
A1 - Schlaad, Helmut
T1 - Kinetics of anionic polymerization of β‐myrcene in hydrocarbon solvents
N2 - AbstractThe kinetics of anionic polymerization of β‐myrcene initiated by sec‐butyllithium were examined in saturated and unsaturated hydrocarbon solvents, i.e. cyclohexane, cyclohexene, 4‐vinylcyclohexene and dl‐limonene. Polymerizations usually proceeded in a living manner, i.e. in the absence of termination and chain transfer reactions, in all solvents, to produce well‐defined polymyrcenes with high content (85%) of cis‐1,4 units. However, polymyrcenyllithium chains exhibited limited long‐term stability in 4‐vinylcyclohexene solution, most probably due to chain transfer to solvent. Reaction orders with respect to the concentration of active chains were found to be one‐quarter in cyclohexane increasing to one‐half in unsaturated solvents, indicating that the polymyrcenyllithium chains are present as tetrameric or dimeric associates, respectively. Apparent activation energies were found to be 81 kJ mol−1 in cyclohexane and 77 kJ mol−1 in dl‐limonene solution, which are close to the values obtained by quantum chemical calculations. © 2025 The Author(s). Polymer International published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
KW - Myrcene
KW - Anionic polymerization
KW - Reaction order
KW - Activation energy
KW - Microstructure
KW - Quantum chemical calculation
PY - 2025
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-636840
DO - https://doi.org/10.1002/pi.6772
SN - 0959-8103
SP - 1
EP - 8
PB - Wiley
AN - OPUS4-63684
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Rösler, Alexander
A1 - Weidner, Steffen
A1 - Klamroth, Tillmann
A1 - Müller, Axel HE
A1 - Schlaad, Helmut
T1 - Kinetics of anionic polymerization of β‐myrcene in hydrocarbon solvents
N2 - AbstractThe kinetics of anionic polymerization of β‐myrcene initiated by sec‐butyllithium were examined in saturated and unsaturated hydrocarbon solvents, i.e. cyclohexane, cyclohexene, 4‐vinylcyclohexene and dl‐limonene. Polymerizations usually proceeded in a living manner, i.e. in the absence of termination and chain transfer reactions, in all solvents, to produce well‐defined polymyrcenes with high content (85%) of cis‐1,4 units. However, polymyrcenyllithium chains exhibited limited long‐term stability in 4‐vinylcyclohexene solution, most probably due to chain transfer to solvent. Reaction orders with respect to the concentration of active chains were found to be one‐quarter in cyclohexane increasing to one‐half in unsaturated solvents, indicating that the polymyrcenyllithium chains are present as tetrameric or dimeric associates, respectively. Apparent activation energies were found to be 81 kJ mol−1 in cyclohexane and 77 kJ mol−1 in dl‐limonene solution, which are close to the values obtained by quantum chemical calculations. © 2025 The Author(s). Polymer International published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
KW - Myrcene
KW - Anionic polymerization
KW - MALDI TOF MS
PY - 2025
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-649039
DO - https://doi.org/10.1002/pi.6772
SN - 0959-8103
SP - 1
EP - 8
PB - Wiley
AN - OPUS4-64903
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Schneider, Rudolf
T1 - Antikörperbasierte vor-Ort-Analytik für das Monitoring der Eliminierung von Spurenstoffen in Kläranlagen
N2 - Die Überwachung der Eliminierung von Spurenstoffen in Kläranlagen, wie sie die Neufassung der Kommunalabwasserrichtlinie vorschreibt, ruft einen Bedarf an vor-Ort-Analytik in den Kläranlagen hervor. Immunanalytische Methoden können vor Ort, z.B. in Form von Schnelltests, durchgeführt werden, ideal aber wären kontinuierlich arbeitende (Immuno-Bio)Sensoren. Antikörperbasierte Verfahren weisen als Flaschenhals immanent die Einschränkung auf, dass pro Analyt ein Antikörper zum Einsatz kommen muss und dass daher nur eine kleinere Anzahl von Substanzen analysiert werden kann. Die Indikatorenliste der Abwasserrichtlinie liefert hier einen Anhaltspunkt. Der Artikel weist schon bisher existierende Schnell- und Hochdurchsatzverfahren aus, ebenso wie Forschungsansätze für eine Sensorik, die online einsetzbar wäre und gibt einen Überblick über Defizite und Entwicklungen.
KW - Antikörper
KW - Immunoassay
KW - Schnelltests
KW - Biosensor
PY - 2025
SN - 1618-3258
VL - 31
IS - 1
SP - 12
EP - 14
AN - OPUS4-63510
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Lutz, C.
A1 - Hampel, S.
A1 - Beuermann, S.
A1 - Turek, T.
A1 - Kunz, U.
A1 - de Oliveira Guilherme Buzanich, Ana
A1 - Radtke, Martin
A1 - Fittschen, U. E. A.
T1 - Investigation on Vanadium Species Distribution in Nafion™ 117 after Cyclization in a Vanadium Redox Flow Battery
N2 - The vanadium redox flow battery (VRFB) is currently a potential candidate for stationary energy storage. A major challenge is the unintended vanadium transport through the separator, which results in a fade of capacity. To overcome this issue, it is necessary to understand the transport processes in the membrane on a more fundamental level. In this work, the vanadium species distribution in Nafion™ 117 after cyclization was investigated. Two membranes, one from a charged VRFB and another from a discharged VRFB, were analyzed using ultraviolet–visible spectroscopy (UV/VIS) and X-ray absorption near edge structure spectroscopy (XANES). Little difference between the two membranes was recognizable according to the UV/VIS results. In comparison, the XANES results showed that the membrane from the charged VRFB contains more V3+ than VO2+, whereas for the discharged case, more VO2+ is present in the membrane.
KW - Synchrotron
KW - BAMline
KW - XANES
KW - Vanadium redox flow battery
PY - 2021
VL - 64
SP - 1
EP - 8
AN - OPUS4-54144
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Westwood, S.
A1 - Josephs, R. D.
A1 - Choteau, T.
A1 - Martos, G.
A1 - Wielgosz, R.
A1 - Sarzuri, Y. A.
A1 - Mendoza, E.
A1 - do Rego, E. C. P.
A1 - Violante, F. G. M.
A1 - da Silva Souza, W.
A1 - de Carvalho, L. J.
A1 - Fernandes, J. L. N.
A1 - Bates, J.
A1 - Rajotte, I.
A1 - Melanson, J. E.
A1 - Li, H.
A1 - Guo, Z.
A1 - Su, F.
A1 - Wang, S.
A1 - Huang, T.
A1 - Lalerle, B.
A1 - Gantois, F.
A1 - Piechotta, Christian
A1 - Philipp, Rosemarie
A1 - Kaminski, Katja
A1 - Klyk-Seitz, Urzsula-Anna
A1 - Giannikopoulou, P.
A1 - Skotidaki, E.
A1 - Kakoulides, E.
A1 - Pui-Kwan, C.
A1 - Kuroe, M.
A1 - Itoh, N.
A1 - Calderón, M. A. A.
A1 - Contreras, L. R.
A1 - Osuna, M. A.
A1 - Alrashed, M.
A1 - Ting, L.
A1 - Mei, G. E.
A1 - Juan, W.
A1 - Sze, C. P.
A1 - Lin, T. T.
A1 - Quinn, L.
A1 - Swiegelaar, C.
A1 - Fernandes-Whaley, M.
A1 - Ahn, S.
A1 - Chaiphet, T.
A1 - Sudsiri, N.
A1 - Bellazreg, W.
A1 - Bilsel, M.
A1 - Colombo, G.
T1 - Key comparison CCQM-K78.b - non-polar analytes in organic solvent: methoxychlor and trifluralin in acetonitrile
N2 - The CCQM-K78.b key comparison was coordinated by the Bureau International des Poids et Mesures (BIPM) on behalf of the CCQM Organic Analysis Working Group (OAWG) of the 'Comité Consultatif pour la Quantité de Matière' (CCQM), for National Measurement Institutes (NMIs) and Designated Institutes (DIs) providing measurement services in organic analysis under the 'Comité International des Poids et Mesures' (CIPM) Mutual Recognition Arrangement (MRA).
This key comparison was conducted as a 'Track A' comparison within the OAWG's 10-year strategic plan. The goal of CCQM-K78.b was to underpin capabilities for the value assignment of calibration solutions containing low polarity/non-polar organic analytes in organic solvents. The selected model system consisted of a two-component pesticide solution in acetonitrile, comprising methoxychlor and trifluralin.
Participants were tasked with assigning the mass fractions, in units of μg/g, of methoxychlor and trifluralin in acetonitrile solution. The mass fraction levels and analytical challenges of the selected analytes were representative of those encountered for calibration solutions of non-polar organic analytes. Participation in CCQM-K78.b allowed for the benchmarking of capabilities for assigning the mass fraction of non-polar organic compounds (pKow < -2) in solution, at mass fractions above 5 μg/g, in an organic solvent. Additionally, the comparison assessed the capabilities for the quantitative assignment of thermally labile compounds.
Participants were provided by the BIPM with ampoules containing methoxychlor and trifluralin in acetonitrile. Each participant reported the mass fraction content of each analyte in μg/g. All participants ensured the metrological traceability of their results through the use of a Primary Reference Material (PRM), which was used to prepare a primary calibrator solution for each analyte using a gravimetric procedure. The twenty participating institutes primarily used analysis procedures based on GC-MS, -IDMS, -MS/MS, -ECD, and -FID, with some participants also using LC-UV for the value assignment.
The analysis of methoxychlor and trifluralin in acetonitrile solution presented several challenges, including the thermal stability of the analytes under selected analytical techniques, control of solvent volatility, and considerable variation in some results using MS-based quantification methods. The mass fraction assignments for methoxychlor and trifluralin, consistent with the key comparison reference values (KCRVs), were achieved with associated relative standard uncertainties of (0.38 - 2.9) % for methoxychlor and (0.35 - 2.5) % for trifluralin.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
KW - Methoxychlor
KW - Trifluralin
KW - CCQM
KW - Key comparison
PY - 2025
DO - https://doi.org/10.1088/0026-1394/62/1A/08010
SN - 0026-1394
VL - 62
IS - 1A
SP - 1
EP - 37
PB - IOP Publishing
AN - OPUS4-64691
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Radtke, Martin
A1 - Rakotondrajoa, A.
T1 - Machine learning based quantification of synchrotron radiation-induced X-ray fluorescence measurements - a case study
N2 - In this work, we describe the use of artificial neural networks for the quantification of X-ray fluorescence measurements. The training data were generated using Monte Carlo simulation, which avoided the use of adapted reference materials. The extension of the available data set by means of an ANN to generate additional data was demonstrated. Particular emphasis was put on the comparability of simulated and experimental data and how the influence of deviations can be reduced. The search for the optimal hyperparameter, manual and automatic, is also described. For the presented case, we were able to train a network with a mean absolute error of 0.1 weight percent for the synthetic data and 0.7 weight percent for a set of experimental data obtained with certified reference materials.
KW - Machine learning
KW - BAMline
KW - XRF
KW - Synchrotron
KW - Neural network
PY - 2020
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-519008
DO - https://doi.org/10.1088/2632-2153/abc9fb
SP - 1
EP - 16
PB - IOP Publishing
AN - OPUS4-51900
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Altmann, Korinna
A1 - Goedecke, Caroline
A1 - Bannick, C.-G.
A1 - Abusafia, A.
A1 - Scheid, C.
A1 - Steinmetz, H.
A1 - Paul, Andrea
A1 - Beleites, C.
A1 - Braun, U.
T1 - Identification of microplastic pathways within a typical European urban wastewater system
N2 - In recent years, thermoextraction/desorption-gas chromatography/mass spectrometry (TED-GC/MS) has been developed as a rapid detection method for the determination of microplastics (MP) mass contents in numerous environmentally relevant matrices and, in particular, for the measurement of polymers in water samples without time-consuming sample preparation. The TED-GC/MS method was applied to investigate a typical European municipal wastewater system for possible MP masses. Such investigations are important in view of the recent revision of the Urban Wastewater Treatment Directive. Four different representative sampling sites were selected: greywater (domestic wastewater without toilet), combined sewer, and influent and effluent of a wastewater treatment plant (WWTP). All samples were collected by fractional filtration. Filtration was carried out over mesh sizes of 500, 100, 50, and in some cases, 5 µm. Polyethylene (PE), polypropylene (PP), and polystyrene (PS) were detected in all samples, with the PE fraction dominating in all cases. Styrene-butadiene rubber which serves as an indication of tire abrasion, was only found in the influent of the WWTP. The highest MP mass contents were found in the combined sewer, so MP can become a source of pollution during heavy rain events when the capacity limits of the effluent are reached, and the polluted effluent is released uncontrolled into the environment. Based on the studies, MP retention from the WWTP could be estimated to be approximately 96%. Few trends in polymer type or mass contents were detected within the different fractions of the samples or when comparing samples to each other.
KW - Microplastics
KW - Microplastic analysis
KW - TED-GC/MS
KW - Microplastic pathways
KW - Mass contents
PY - 2023
UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-568289
DO - https://doi.org/doi.org/10.1002/appl.202200078
SP - 1
EP - 10
PB - Wiley-VCH
CY - Weinheim
AN - OPUS4-56828
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Mi, W.
A1 - Josephs, R. D.
A1 - Melanson, J. E.
A1 - Dai, X.
A1 - Wang, Y.
A1 - Zhai, R.
A1 - Chu, Z.
A1 - Fang, X.
A1 - Thibeault, M.-P.
A1 - Stocks, B. B.
A1 - Meija, J.
A1 - Bedu, M.
A1 - Martos, G.
A1 - Westwood, S.
A1 - Wielgosz, R. I.
A1 - Liu, Q.
A1 - Teo, T. L.
A1 - Liu, H.
A1 - Tan, Y. J.
A1 - Öztuğ, M.
A1 - Saban, E.
A1 - Kinumi, T.
A1 - Saikusa, K.
A1 - Schneider, Rudolf
A1 - Weller, Michael G.
A1 - Konthur, Zoltán
A1 - Jaeger, Carsten
A1 - Quaglia, M.
A1 - Mussell, C.
A1 - Drinkwater, G.
A1 - Giangrande, C.
A1 - Vaneeckhoutte, H.
A1 - Boeuf, A.
A1 - Delatour, V.
A1 - Lee, J. E.
A1 - O'Connor, G.
A1 - Ohlendorf, R.
A1 - Henrion, A.
A1 - Beltrão, P. J.
A1 - Naressi Scapin, S. M.
A1 - Sade, Y. B.
T1 - PAWG Pilot Study on Quantification of SARS-CoV-2 Monoclonal Antibody - Part 1
N2 - Under the auspices of the Protein Analysis Working Group (PAWG) of the Comité Consultatif pour la Quantité de Matière (CCQM) a pilot study, CCQM-P216, was coordinated by the Chinese National Institute of Metrology (NIM), National Research Council of Canada (NRC) and the Bureau International des Poids et Mesures (BIPM). Eleven Metrology Institutes or Designated Institutes and the BIPM participated in the first phase of the pilot study (Part 1). The purpose of this pilot study was to develop measurement capabilities for larger proteins using a recombinant humanized IgG monoclonal antibody against Spike glycoprotein of SARS-CoV-2 (Anti-S IgG mAb) in solution. The first phase of the study was designed to employ established methods that had been previously studies by the CCQM Protein Analysis Working Group, involving the digestion of protein down to the peptide or amino acid level. The global coronavirus pandemic has also led to increased focus on antibody quantitation methods. IgG are among the immunoglobulins produced by the immune system to provide protection against SARS-CoV-2. Anti-SARS-CoV-2 IgG can therefore be detected in samples from affected patients. Antibody tests can show whether a person has been exposed to the SARS-CoV-2, and whether or not they potentially show lasting immunity to the disease. With the constant spread of the virus and the high pressure of re-opening economies, antibody testing plays a critical role in the fight against COVID-19 by helping healthcare professionals to identify individuals who have developed an immune response, either via vaccination or exposure to the virus. Many countries have launched large-scale antibody testing for COVID-19. The development of measurement standards for the antibody detection of SARS-CoV-2 is critically important to deal with the challenges of the COVID-19 pandemic. In this study, the SARS-CoV-2 monoclonal antibody is being used as a model system to build capacity in methods that can be used in antibody quantification. Amino acid reference values with corresponding expanded uncertainty of 36.10 ± 1.55 mg/kg, 38.75 ± 1.45 mg/kg, 18.46 ± 0.78 mg/kg, 16.20 ± 0.67 mg/kg and 30.61 ± 1.30 mg/kg have been established for leucine, valine, phenylalanine, isoleucine and proline, respectively. Agreement between nearly all laboratories was achieved for the amino acid analysis within 2 to 2.5 %, with one participant achieving markedly higher results due to a technical issue found in their procedure; this result was thus excluded from the reference value calculations. The relatively good agreement within a laboratory between different amino acids was not dissimilar to previous results for peptides or small proteins, indicating that factors such as hydrolysis conditions and calibration procedures could be the largest sources of variability. Peptide reference values with corresponding expanded uncertainty of 4.99 ± 0.28 mg/kg and 6.83 ± 0.65 mg/kg have been established for ALPAPIEK and GPSVFPLAPSSK, respectively. Not surprisingly due to prior knowledge from previous studies on peptide quantitation, agreement between laboratories for the peptide-based analysis was slightly poorer at 3 to 5 %, with one laboratory's result excluded for the peptide GPSVFPLAPSSK. Again, this level of agreement was not significantly poorer than that achieved in previous studies with smaller or less complex proteins. To reach the main text of this paper, click on Final Report.
KW - Antibody quantification
KW - Amino acid analysis
KW - Peptide analysis
KW - Round robin test
PY - 2021
DO - https://doi.org/10.1088/0026-1394/59/1a/08001
VL - 59
IS - 1A
SP - 08001
AN - OPUS4-54972
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Wiesner, Yosri
A1 - Altmann, Korinna
A1 - Braun, U.
T1 - Determination of Microplastic Mass Content by Thermal Extraction Desorption Gas Chromatography– Mass Spectrometry
N2 - The scientific and practical challenge of detecting microplastics (MPs) in the environment in a targeted and rapid manner is solved by innovative coupling of thermogravimetric analysis with mass spectrometric methods.
Fast identification and quantitative determination of most thermoplastic polymers and elastomers is possible by using thermal extraction Desorption gas chromatography–mass spectrometry (TED-GC–MS).
KW - Microplastics
KW - Mikroplastik
KW - TED-GC/MS
KW - Microplastics analytic
KW - Mikroplastik Massegehalt
PY - 2021
VL - 17
IS - 3
SP - 2
EP - 7
PB - MultiMedia (UK) LLC
CY - Cranbury
AN - OPUS4-52570
LA - eng
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -
TY - JOUR
A1 - Eisentraut, Paul
A1 - Altmann, Korinna
T1 - Repräsentative Mikroplastik-Detektion in Umweltproben - Weiterentwicklung der TED-GC/MS
N2 - Die große Herausforderung in der Detektion von Mikroplastik (MP)‑Partikeln (1-1000 µm) besteht darin, sie neben Millionen von natürlichen Partikeln in Umweltproben nachzuweisen. Zum Aufspüren von Senken, Eintragspfaden und für Monitoring-Kampagnen ist ein schnelles, automatisiertes Verfahren unerlässlich. Ein solches Verfahren wurde an der Bundesanstalt für Materialforschung und -prüfung (BAM) mit der ThermoExtraktion/Desorption-Gaschromatographie-Massenspektrometrie (TED-GC/MS) in den letzten Jahren entwickelt.
KW - Mikroplastik
KW - TED-GC/MS
PY - 2021
UR - https://analyticalscience.wiley.com/do/10.1002/was.0004000195
SN - 0016-3538
SP - 2
EP - 5
PB - Wiley-VCH
CY - Weinheim
AN - OPUS4-54266
LA - deu
AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER -