TY - CHAP A1 - Vogel, Christian A1 - Roesch, Philipp A1 - Wittwer, Philipp A1 - Simon, Franz-Georg ED - Holm, O. ED - Thomé-Kozmiensky, E. ED - Quicker, P. ED - Kopp-Assenmacher, S. T1 - Per- und polyfluorierte Alkylsubstanzen (PFAS) im Klärschlamm N2 - Per- and polyfluoroalkyl substances (PFAS) are a group of more than 4700 anionic and cationic anthrophonic substances which have been used extensively in a variety of products and industries due to their inert chemical stability and resistance to degradation by heat or acids. As a result of continuous use, mainly in aviation firefighting foams, thousands of industrial and military installations have been found to contain contaminated soil and groundwater resources. However, because of the continuous use of fluorinated consumer products, also effluents and sewage sludge from wastewater treatment plants (WWTPs) have been shown to be an important source of PFAS contamination into the aquatic environment. Resulting from recent stricter regulations and restrictions in the last years on the use of long chain (≥C8) PFAS, there is a significant shift in the chemical industry towards production of short (C4-C7) and ultrashort (C1-C3) chain alternatives. With the amendment of the Sewage Sludge Ordinance in 2017 the German legislation banned sewage sludge application on agricultural land, and by 2029/2032 sewage sludge will be completely prohibited from agricultural application. While environmental exposure of organic pollutants like PFAS, pesticides and pharmaceuticals are no longer desirable, phosphorus (P) from sewage sludge must still be used to produce high-quality P-fertilizers for a circular economy. Currently, plant-available P-fertilizers from sewage sludge/wastewater can be produced using a variety of treatment approaches including precipitation, leaching, and thermal treatment. However, the fate of legacy and emerging PFAS compounds during P leaching, precipitation and treatment from sewage sludge and wastewater is for the most parts still unknown. KW - Combustion Ion Chromatography KW - Per- and Polyfluoroalkyl substances (PFAS) KW - Klärschlamm KW - Düngemittel PY - 2022 SN - 978-3-944310-65-7 SP - 270 EP - 279 PB - Thomé-Kozmiensky Verlag GmbH CY - Neuruppin AN - OPUS4-56290 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Vogel, Christian A1 - Slee, D. ED - Naidu, R. T1 - Chapter 5 Analytical techniques for Per- and Polyfluoroalkyl substances (PFAS) N2 - Per- and polyfluoroalkyl substances (PFAS) are a group of various anthropogenic organic products, in which the hydrogen atoms on the carbon skeleton of at least one carbon atom have been completely replaced by fluorine atoms. Because this group contains more than 7 million compounds, they can have very different properties. PFAS analysis in environmental samples is currently mainly utilized by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and related techniques as well as gas chromatography-mass spectrometry (GC-MS) to conduct target analysis. However, to get a better overview of the amount of “total” amount of PFAS, sum parameter methods like total oxidizable precursor assay (TOPA), absorbable organic fluorine (AOF), and extractable organic fluorine (EOF) are in development. Additionally, for research purposes, several spectroscopical methods like X-ray photoelectron spectroscopy (XPS), fluorine K-edge X-ray absorption near-edge structure (XANES) spectroscopy, particular induced gamma-ray emission (PIGE) spectroscopy as well as19 F nuclear magnetic resonance (NMR), infrared, and Raman spectroscopy are available. Therefore, an overview is given on currently available analytical techniques for PFAS in environmental samples and their application possibilities discussed for different kinds of PFAS subgroups. KW - Per- and polyfluoroalkyl substances (PFAS) KW - Analytics KW - Liquid chromatography - mass spectrometry (GC-MS) KW - Sum parameter PY - 2025 DO - https://doi.org/10.1515/9783110796797-005 SP - 143 EP - 168 PB - De Gruyter AN - OPUS4-62662 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Holstein, Tanja A1 - Muth, Thilo ED - Salerno, C. T1 - Bioinformatic workflows for metaproteomics N2 - The strong influence of microbiomes on areas such as ecology and human health has become widely recognized in the past years. Accordingly, various techniques for the investigation of the composition and function of microbial community samples have been developed. Metaproteomics, the comprehensive analysis of the proteins from microbial communities, allows for the investigation of not only the taxonomy but also the functional and quantitative composition of microbiome samples. Due to the complexity of the investigated communities, methods developed for single organism proteomics cannot be readily applied to metaproteomic samples. For this purpose, methods specifically tailored to metaproteomics are required. In this work, a detailed overview of current bioinformatic solutions and protocols in metaproteomics is given. After an introduction to the proteomic database search, the metaproteomic post-processing steps are explained in detail. Ten specific bioinformatic software solutions are focused on, covering various steps including database-driven identification and quantification as well as taxonomic and functional assignment. KW - Metaproteomics KW - Microbiomes KW - Proteomics KW - Bioinformatic workflow KW - Taxonomic assignment KW - Functional assignment KW - Protein quantification PY - 2024 SN - 978-1-0716-3909-2 SN - 978-1-0716-3910-8 SN - 978-1-0716-3912-2 DO - https://doi.org/10.1007/978-1-0716-3910-8_16 SN - 1064-3745 SN - 1940-6029 N1 - Serientitel: Methods in molecular biology – Series title: Methods in molecular biology VL - 2820 SP - 187 EP - 213 PB - Springer CY - New York, NY AN - OPUS4-62741 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Traub, Heike ED - Milacic, R. ED - Scancar, J. ED - Goenaga-Infante, H. ED - Vidmar, J. T1 - Imaging of metal-based nanoparticles in tissue and cell samples by laser ablation inductively coupled plasma mass spectrometry N2 - Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is nowadays a versatile and powerful analytical method for direct solid sample analysis. The applicability has been demonstrated for a wide variety of samples covering hard and soft materials. In an imaging mode the technique provides quantitative information on the elemental distribution within a sample. LA-ICP-MS imaging is of particular interest in biomedical research as the distribution of an element gives valuable insight on uptake and distribution of essential and toxic trace elements, administered contrast agents as well es nanoparticles. LA-ICP-MS is therefore a powerful complement to other imaging techniques. Recent instrumental improvements, especially in sample chamber design, have contributed to better sensitivity and spatial resolution enabling subcellular imaging. The book chapter provides a comprehensive overview about spatially resolved localisation and quantification of various nanoparticles in cells and tissue thin sections by LA-ICP-MS. Furthermore, different sample preparation strategies and internal standardisation and calibration approaches for bioimaging by LA-ICP-MS are summarized and discussed. Metal-containing nanomaterials are used in numerous fields ranging from industrial applications to nanomedicine. Several studies have demonstrated that the physicochemical properties of nanoparticles have an impact on their pharmacokinetics, transfer and clearance. The high sensitivity and multielement capability of LA-ICP-MS enables the elucidation of interactions between tissue components and nanomaterials used as imaging probes or drug carriers. Potential toxic effects are investigated as well. Thus, LA imaging significantly supports the clinical translation of safe and efficient nanoparticles for diagnostic and therapeutic purposes. KW - Laser ablation KW - ICP-MS KW - Imaging KW - Nanoparticle KW - Nanomaterial KW - Tissue KW - Cell PY - 2021 SN - 978-0-323-85305-7 SN - 0166-526X VL - 93 SP - 173 EP - 240 PB - Elsevier CY - Amsterdam ET - 1 AN - OPUS4-52775 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Theiner, S. A1 - Corte Rodriguez, M. A1 - Traub, Heike ED - Golloch, A. T1 - Novel applications of lanthanoids as analytical or diagnostic tools in the life sciences by ICP-MS based techniques N2 - Inductively coupled plasma-mass spectrometry (ICP-MS) is a well-established analytical method offering high sensitivity and multi-element analysis. ICP-MS has found acceptance in various application areas ranging from material analysis to applications in the life sciences. Within the last 15 years new strategies for the sensitive detection and accurate quantification of biomolecules in complex biomedical samples have been developed. Recent instrumental improvements have contributed to this progress. As most of the biomolecules do not contain endogenous metals etectable with ICP-MS, bioconjugation with artificial metal-containing tags based on metal-loaded chelate complexes or nanoparticles is increasingly applied to determine biomolecules indirectly. Especially, the combination of immunohistochemical workflows using lanthanoid-tagged antibodies and ICP-MS detection provides new insights in the complexity and interdependency of cellular processes. Single-cell ICP-MS, also termed as mass cytometry, allows high-dimensional analysis of biomarkers in cell populations at single-cell resolution. For that purpose, lanthanoid isotope labelled antibodies are used to detect their corresponding target molecules. The visualisation of the elemental distribution is possible with laser ablation ICP-MS (LA-ICPMS) at high spatial resolution. Especially, the combination of LA with ICP time-of-flight mass spectrometry, also referred to as imaging mass cytometry (IMC), opens new possibilities for multiparametric tissue imaging at the single-cell level and even below. The lanthanoid localisation and concentration can be linked to their conjugated antibody target providing valuable information about surface markers, intracellular signalling molecules to measure biological function, and the network state of an individual cell in a tissue. This book chapter focuses on new applications, where the multi-element capabilities of ICP-MS are used for the detection of lanthanoids applied as artificial elemental stains or tags for biomolecules and in particular antibodies. KW - ICP-MS KW - Laser ablation KW - Cell KW - Antibody KW - Immunohistochemistry KW - Lanthanoid KW - Mass cytometry KW - Imaging PY - 2022 SN - 978-3-11069-645-5 SN - 978-3-11069-636-3 DO - https://doi.org/10.1515/9783110696455-013 SP - 399 EP - 444 PB - De Gruyter CY - Berlin, Boston ET - 2. rev. and exten. edition AN - OPUS4-55118 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Hahn, Oliver A1 - Golle, U. A1 - Wintermann, Carsten A1 - Laurenza, D. ED - Quenzer, J. B. T1 - Scientific Analysis of Leonardo’s Manuscript with Anatomic Drawings and Notes N2 - In this paper, we discuss the importance of scientifically investigating cultural artefacts in a non-invasive way. Taking as test case Leonardo da Vinci’s Manuscript with anatomic drawings and notes, which is stored in Weimar, we clarify fundamental steps in the chronology of this folio. By means of microscopy, infrared reflectography, UV photography, and X-ray fluorescence analysis, we were able to identify various types of sketching material and several varieties of iron gall ink. For his sketches, Leonardo used two different sketching tools, a lead pencil and a graphite pencil, as well as several types of ink for developing these sketches into drawings. With regard to ink, it is important to observe that there is no difference between the ink Leonardo used for drawing and the ink he used for writing text. Based on the materials analysed, we suggest a chronology for the creation of this unique folio. KW - Archaeometry KW - Non-invasive analysis KW - Drawings KW - Leonardo da Vinci PY - 2021 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-543460 SN - 978-3-11-074545-0 DO - https://doi.org/10.1515/9783110753301-011 VL - 25 SP - 213 EP - 228 PB - Walter de Gruyter GmbH CY - Berlin/Boston AN - OPUS4-54346 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Helman-Wasny, Agnieszka ED - Martin, E. ED - Brox, T. ED - Lange, D. T1 - What makes ‘Tibetan paper’ Tibetan? Understanding the materiality of Tibetan paper N2 - Paper, as a writing support, is an integral element of the materiality of Tibetan books together with the technologies of their production. Analysis of the material features of the paper used in Tibetan written artefacts can help us to unravel their provenance, which is often unknown. First, however, we need a relatively clear understanding of the characteristic features of paper produced within particular book cultures and geographical regions at particular periods of time. This chapter offers a starting point by discussing the general characteristics of paper that originated in Tibet. Drawing on macro- and microscopic studies, it highlights the wide variety of paper types that have been used as writing supports in Tibetan written artefacts, before examining in more detail the raw materials, papermaking technologies and processes, and writing surface preparations that might justify the descriptor ‘Tibetan’ and thus grant Tibetan identity to paper. KW - Written artefacts KW - Paper KW - Tibet PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-649288 SN - 978-3-98887-016-2 DO - https://doi.org/10.11588/hasp.1522 SP - 113 EP - 146 PB - Heidelberg Asian Studies Publishing (HASP) CY - Heidelberg AN - OPUS4-64928 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Lange, D. A1 - Hahn, Oliver ED - Martin, E. ED - Brox, T. ED - Lange, D. T1 - Materials and materiality as keys to understanding a map of Mount Kailash N2 - While graphic and linguistic content is central to the identification of maps and can provide insights into the concepts and systems of rules, ideas and beliefs that led to their production, the materials that constitute maps may speak about manufacturing processes, the provenance of raw materials, the practical and technical knowledge of the mapmakers, and the use of the maps. This contribution underscores how the materials employed in Tibetan maps reveal aspects of their context and trajectory. Furthermore, materiality, conceptualized as a convergence of matter and imagination, can yield even more profound insights into artefacts like maps. Through a detailed case study of a map of Mount Kailash in the tangkha format and a specialized material-scientific analysis of the colourants employed in its creation, this contribution explores how a map can ‘talk’ through its materiality. With this case study it will show how Tibetan Studies can benefit from interdisciplinary collaboration. Crossing the field’s traditional boundaries and working with other disciplines, we argue, is absolutely essential for serious research. KW - Archaeometry KW - Non-destructive analysis KW - Cultural heritage PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-648625 SN - 978-3-98887-016-2 DO - https://doi.org/10.11588/hasp.1522 SP - 147 EP - 176 PB - Heidelberg Asian Studies Publishing (HASP) CY - Heidelberg AN - OPUS4-64862 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Radtke, Martin A1 - Reinholz, Uwe A1 - Guerra, M.F. A1 - Martinón-Torres, M. A1 - Lemasson, Q. A1 - Moignard, B. A1 - Pacheco, C. A1 - Pichon, L. A1 - Macdonald, L. A1 - Hess, M. A1 - Tissot, I. ED - Guerra, M. F. ED - Martinón-Torres, M. ED - Quirke, S. T1 - Analytical approaches to Egyptian goldwork N2 - The structure and composition of ancient gold objects retain information about their long history of manufacture, from the exploitation of the ore to the finishing touches, as well as evidence of their use, deposition, and degradation. By developing an efficient analytical strategy, it is possible to retrieve that information. This chapter sets the necessary foundation 131to explore fully the analytical results presented in the following chapters of this volume. The techniques employed in the analyses of the Egyptian jewellery are described and the analytical parameters provided. For more established techniques, only brief introductions are presented, while more recent developments are presented in greater detail. KW - Gold KW - Synchrotron KW - D2XRF KW - Egypt PY - 2023 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-586039 DO - https://doi.org/10.17863/CAM.99681 SP - 131 EP - 191 AN - OPUS4-58603 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Rabin, Ira A1 - Cohen, Zina ED - Corazzol, Giacomo ED - Fargeon, Sarah T1 - Black inks in medieval Jewish manuscripts N2 - Our aim was to obtain information about the use of different black inks in medieval Hebrew manuscripts, focusing on the question of possible preferences in the use of certain inks by different scribes. We present here an overview of the inks detected in a selection of Hebrew documents penned in the Middle East in the period from the 11th century to the 13th century. KW - Historic ink KW - Ink KW - Hebrew manuscripts KW - XRF KW - NIR PY - 2025 UR - https://books.openedition.org/ephe/2673?lang=en DO - https://doi.org/10.4000/13sug SP - 13 EP - 30 CY - Paris AN - OPUS4-65349 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Hahn, Oliver ED - Corbach, A. ED - Suchenwirth, R. H. R. T1 - Arsen im Papier - Materialwissenschaftliche Untersuchungen von Bibliotheksgut N2 - Materialwissenschaftliche Analysen werden an Bibliotheksgut durchgeführt, um kulturhistorische, restauratorische oder konservatorische Fragestellungen zu beantworten. Sie ermöglichen somit auch die Bestimmung von Art und Zusammensetzung arsenhaltiger Komponenten und erlauben Rückschlüsse darüber, ob diese durch Alterung und Korrosion freigesetzt werden können. Hier kann jedoch nur eine erste Einschätzung des Gefährdungspotenzials erfolgen; genaue Rückschlüsse auf die Konzentrationen in Raumluft oder Staub sind nur durch weiterführende Untersuchungen möglich. Es besteht ein Unterschied zwischen der Feststellung arsenhaltiger Substanzen in Bibliotheksgut und der Frage, ob diese auch tatsächlich freigesetzt werden. Dies wird am Beispiel der beiden Pigmente Smalte und Auripigment diskutiert. KW - Bibliotheksgut KW - Arsen KW - Zerstörungsfreie Prüfung PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-652376 SN - 978-3-447-12463-8 DO - https://doi.org/10.13173/WIF.6.037 VL - 6 SP - 37 EP - 45 PB - Harrassowitz CY - Wiesbaden AN - OPUS4-65237 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Hahn, Oliver A1 - Steimer, Hans Gerhard ED - Christen, Felix ED - Vöhler, Martin T1 - Hölderlins Tinten. Röntgenfluoreszenzanalyse an Handschriften des Spätwerks N2 - Erstmalig in der Hölderlin-Forschung wurde mit dem Projekt der geisteswissenschaftlichen Methodik – über die Beachtung der Wasserzeichen hinaus – ein materialwissenschaftlicher Ansatz zur Seite gestellt, um Arbeitsphasen im Werk Friedrich Hölderlins sichtbar zu machen. Wesentlich ist dabei die Verzahnung von philologischer und naturwissenschaftlicher Perspektive. Wesentlicher Bestandteil der Messungen bildet das sogenannte Homburger Folioheft. Weiterhin wurden Briefe und Manuskripte aus den Beständen der Württembergische Landesbibliothek sowie zwei eigenhändige Gehaltsquittungen aus dem Hessischen Hauptstaatsarchiv Wiesbaden untersucht. Zwei in mehreren Manuskripten klar unterscheidbare Tinten lassen sich mit einiger Wahrscheinlichkeit biografisch mit dem Zeitraum zwischen Hölderlins Rückkehr aus der Schweiz im April 1801 und seinem Weggang nach Frankreich im Dezember dieses Jahres in Verbindung bringen. Für den in den untersuchten Handschriften häufigsten Tintentyp liegen datierbare Belege zwischen Januar 1803 und März 1804 vor, anzunehmen ist seine Verwendung zwischen Oktober 1802 und Juni 1804. Er dominiert auch im Homburger Folioheft. Eine vierte mehrfach vertretene Tinte gebraucht Hölderlin nach seiner Übersiedlung von Nürtingen nach Homburg. Sie findet sich im Folioheft und in einigen Einzelhandschriften. Damit können die in der Forschung umstrittenen Fragen geklärt werden, a) ob dem Dichter das Homburger Folioheft bei seinem zweiten Aufenthalt in Homburg zur Verfügung stand und b) ob überhaupt Werkhandschriften aus dieser Zeit erhalten sind. Darüber hinaus lässt sich über die Röntgenfluoreszenzanalyse der Arbeitsstand in den untersuchten Manuskripten zum Zeitpunkt des Ortswechsels im Juni 1804 genau angeben. Auch Einzelbefunde singulärer oder in nur wenigen Stücken belegter Tinten geben gelegentlich Anhaltspunkte zur Datierung. KW - Manuskript KW - Röntgenfluoreszenzanalyse KW - Eisengallustinte PY - 2026 SN - 978-3-7705-7073-7 SN - 0340-6849 VL - 44 SP - 287 EP - 335 PB - Brill CY - Paderborn AN - OPUS4-65600 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -