TY - JOUR A1 - Reck, Günter A1 - Becker, Roland T1 - (N,N-Diiso­butyl­di­thio­carbamoyl­sulfinato)­zinc(II) JF - Acta crystallographica E N2 - Zinc di­alkyl di­thio­carbamoyl­sulfinates have been proposed as intermediates in the antioxidant action of the respective zinc di­alkyl di­thio­carbamate additives in hydro­carbon-based plastics and lubricants. As a model compound, zinc diiso­butyl di­thio­carbamoyl­sulfinate, [Zn(C9H18NO2S2)2], has been prepared and its crystal structure determined. PY - 2003 DO - https://doi.org/10.1107/S160053680301314X SN - 1600-5368 VL - 59 IS - 7 SP - m489 EP - m490 PB - Munksgaard CY - Copenhagen AN - OPUS4-2577 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Fischer-Tenhagen, C. A1 - Johnen, D. A1 - Nehls, Irene A1 - Becker, Roland T1 - A Proof of Concept: Are Detection Dogs a Useful Tool to Verify Potential Biomarkers for Lung Cancer? JF - Frontiers in Veterinary Science N2 - Early and reliable diagnostic test is essential for effective therapy of lung cancer. Volatile organic compounds that are characteristic for cancer could serve as valuable biomarkers in cancer diagnosis. Both trace analytical and detection dog approaches give some evidence for the existence of such biomarkers. In this proof of concept, study dogs and trace analysis were implemented in combination to gain more information concerning cancer biomarkers. Two dogs were trained to distinguish between absorbed breath samples of lung cancer patients and healthy persons and succeeded with correct identification of patients with 9/9 and 8/9 and correct negative indications from of 8/10 and 4/10 samples from healthy individuals. A recent observational study found that breath samples from lung cancer patients showed an increase in 1-butanol, 2-butanone, 2-pentanone, and hexanal. Synthetic air samples were therefore fortified with these compounds and adsorbed to a fleece. Tested against breath samples from healthy probands, on presentation to the dogs these synthetic samples provoked an indication in three out of four samples. We were able to demonstrate that a combination of the natural nose of a dog and a trace analytic technique can be a valuable concept in the search for cancer biomarkers. KW - Lung cancer KW - Breath KW - Detection dog KW - Biomarkers KW - Sampling KW - Synthetic air PY - 2018 DO - https://doi.org/10.3389/fvets.2018.00052 SN - 2297-1769 VL - 5 SP - Article 52,1 EP - 6 PB - Frontiers Research Foundation CY - Lausanne AN - OPUS4-44466 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Sanchez-Martin, Pedro A1 - Becker, Roland A1 - Toepel, J. A1 - Gorbushina, Anna T1 - An improved test for the evaluation of hydrocarbon degradation capacities of diesel-contaminating microorganisms JF - International Biodeterioration & Biodegradation N2 - The development of a test to evaluate the degradation of semi-volatile fuels as diesel by microorganisms is presented. This method is based on the principles described in the CEC-L-103 Standard procedure that is exclusively meant for testing the biodegradability of non-volatile lubricants. Therefore, significant modifications involve aseptic conditions for testing specific microorganisms and conducting the test in closed vessels avoiding evaporation losses, while fuel quantification using gas chromatography-flame ionization detection (GC-FID) is retained. It is suggested that the modified procedure should enable routine application for semi-volatile hydrocarbon-based fuels. GC-FID provides additionally valuable information on the alteration of fuel component patterns during biodegradation. The procedure was successfully tested using two bacteria (Pseudomonas aeruginosa and Sphingomonas sp.) and two yeasts (Moesziomyces sp. and Candida sp.) isolated from real diesel contamination cases. All tested microorganisms caused a significant degradation of diesel fuel achieving hydrocarbon degradation percentages ranging from 23% to 35%. Specific aspects on the test modification and prospects for further modification regarding targeted investigations in the field of fuel contamination by microorganisms are briefly discussed. KW - Biofouling KW - Bacteria KW - Fungi KW - CEC-L-103 KW - GC-FID KW - Reference organisms PY - 2018 DO - https://doi.org/10.1016/j.ibiod.2018.01.009 SN - 0964-8305 VL - 129 SP - 89 EP - 94 PB - Elsevier AN - OPUS4-44524 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Scholz, Philipp A1 - Wachtendorf, Volker A1 - Elert, Anna Maria A1 - Falkenhagen, Jana A1 - Becker, Roland A1 - Hoffmann, Katrin A1 - Resch-Genger, Ute A1 - Tschiche, Harald A1 - Reinsch, Stefan A1 - Weidner, Steffen ED - Scholz, Philipp T1 - Analytical toolset to characterize polyurethanes after exposure to artificial weathering under systematically varied moisture conditions JF - Polymer Testing N2 - Polyether and -ester urethanes (PU) were exposed to artificial weathering at 40 °C and artificial UV radiation in a weathering chamber. In 3 parallel exposures, humidity was varied between dry, humid, and wet conditions. Material alteration was investigated by various analytical techniques like size exclusion chromatography (SEC), liquid chromatography-infrared spectroscopy (LC-FTIR), thermal-desorption gas chromatography-mass spectrometry (TD-GC-MS), fluorescence mapping and dynamic mechanical analysis (DMA). Our results show that depending on the weathering conditions, different degradation effects can be observed. By means of SEC an initial strong decrease of the molar masses and a broadening of the mass distributions was found. After a material dependent time span this was followed by a plateau where molar mass changes were less significant. A minor moisture-dependent degradation effect was only found for polyester PU. Fluorescence measurements on two materials revealed an increase in the luminescence intensity upon weathering process reaching a saturation level after about 500 h. The changes in the optical properties observed after different exposure conditions and times were very similar. The TD-GC-MS data showed the fate of the stabilizers and antioxidant in the course of weathering. LC-FTIR measurements revealed a change in peak intensities and the ratio of urethane and carbonyl bands. KW - Polyurethane KW - Artificial weathering KW - Moisture KW - Crosslinking KW - Degradation PY - 2019 UR - https://www.sciencedirect.com/science/article/pii/S0142941819303708 DO - https://doi.org/10.1016/j.polymertesting.2019.105996 SN - 0142-9418 VL - 78 SP - 105996, 1 EP - 9 PB - Elsevier CY - Amsterdam AN - OPUS4-48625 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Esslinger, Susanne A1 - Becker, Roland A1 - Müller-Belecke, A. A1 - Jung, Christian A1 - Nehls, Irene T1 - Bioisomerization of HBCD: Results of feeding experiments with pure Gamma-HBCD enantiomers T2 - Dioxin 2009 - 29th International symposium on halogenated persistent organic pollutants / Organohalogen compounds (Proceedings) N2 - 1,2,5,6,9,10-hexabromocyclododecane (HBCD), a widely used flame retardant, is an ubiquitous contaminant in the environment. Still, only little is known about the distribution and behavior in the environment such as bioaccumulation or biotransformation of HBCD stereoisomers. In order to investigate enrichment and possible bioisomerization of HBCD stereoisomers, Mirror Carps were exposed to pure (+)- and (-)-γ-HBCD, randomly sampled after a predefined specific period and subjected to enantiomer-specific determination of α-, β-, and γ- HBCD. No evidence for the isomerization of HBCD stereoisomers was observed in Mirror Carp fillets. T2 - Dioxin 2009 - 29th International symposium on halogenated persistent organic pollutants / Organohalogen compounds CY - Beijing, China DA - 2009-08-23 PY - 2009 UR - http://www.dioxin20xx.org/pdfs/2009/09-103.pdf VL - 71 SP - 000487 EP - 000492 CY - Beijing, China AN - OPUS4-21187 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Reck, Günter A1 - Becker, Roland T1 - Bis­[N-n-butyl-N-(3,5-di-tert-butyl-2-hydroxy­benzyl)­di­thio­carbamato-Kappa²S,S']zinc(II) JF - Acta crystallographica E N2 - Both zinc di­thio­carbamates and sterically hindered phenols are known to exhibit antioxidant activity. As part of an investigation on the effect of both moieties being combined in one mol­ecule, the title compound, [Zn(C17H26NOS2)2], has been prepared and its crystal structure determined. PY - 2003 DO - https://doi.org/10.1107/S1600536803007372 SN - 1600-5368 VL - 59 IS - 5 SP - m234 EP - m235 PB - Munksgaard CY - Copenhagen AN - OPUS4-2464 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ricci, M. A1 - Shegunova, P. A1 - Conneely, P. A1 - Becker, Roland A1 - Torres, M. M. A1 - Osuna, M. A. A1 - On, T.P. A1 - Man, L.H. A1 - Baek, S.-Y. A1 - Kim, B. A1 - Hopley, C. A1 - Liscio, C. A1 - Warren, J. A1 - Le Diouron, V. A1 - Lardy-Fontan, S. A1 - Lalere, B. A1 - Mingwu, S. A1 - Kucklick, J. A1 - Vamathevan, V. A1 - Matsuyama, S. A1 - Numata, M. A1 - Brits, M. A1 - Quinn, L. A1 - Fernandes-Whaley, M. A1 - Gören, A.C. A1 - Binici, B. A1 - Konopelko, L. A1 - Krylov, A. A1 - Mikheeva, A. T1 - CCQM-K102: Polybrominated diphenyl ethers in sediment JF - Metrologia N2 - The key comparison CCQM-K102: Polybrominated diphenyl ethers in sediment was coordinated by the JRC, Directorate F - Health, Consumers & Reference Materials, Geel (Belgium) under the auspices of the Organic Analysis Working Group (OAWG) of the Comité Consultatif pour la Quantité de Matière (CCQM). Thirteen National Metrology institutes or Designated Institutes and the JRC participated. Participants were requested to report the mass fraction (on a dry mass basis) of BDE 47, 99 and 153 in the freshwater sediment study material. The sediment originated from a river in Belgium and contained PBDEs (and other pollutants) at levels commonly found in environmental samples. The comparison was designed to demonstrate participants' capability of analysing non-polar organic molecules in abiotic dried matrices (approximate range of molecular weights: 100 to 800 g/mol, polarity corresponding to pKow < −2, range of mass fraction: 1–1000 μg/kg). All participants (except one using ultrasonic extraction) applied Pressurised Liquid Extraction or Soxhlet, while the instrumental analysis was performed with GC-MS/MS, GC-MS or GC-HRMS. Isotope Dilution Mass Spectrometry approach was used for quantification (except in one case). The assigned Key Comparison Reference Values (KCRVs) were the medians of thirteen results for BDE 47 and eleven results for BDE 99 and 153, respectively. BDE 47 was assigned a KCRV of 15.60 μg/kg with a combined standard uncertainty of 0.41 μg/kg, BDE 99 was assigned a KCRV of 33.69 μg/kg with a combined standard uncertainty of 0.81 μg/kg and BDE 153 was assigned a KCRV of 6.28 μg/kg with a combined standard uncertainty of 0.28 μg/kg. The k-factor for the estimation of the expanded uncertainty of the KCRVs was chosen as k = 2. KW - Intercomparison KW - Traceability KW - Nation metrology institutes PY - 2017 DO - https://doi.org/10.1088/0026-1394/54/1A/08026 SN - 0026-1394 SN - 1681-7575 VL - 54 SP - 08026, 1 EP - 82 AN - OPUS4-41998 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Scharf, Holger A1 - Becker, Roland A1 - Bremser, Wolfram A1 - Buge, Hans-Gerhard A1 - Lück, Detlef T1 - Certification of the mass fractions of trace elements and pentachlorophenol in an impregnated wood reference material JF - Accreditation and quality assurance N2 - The resource-saving utilisation of recovered waste wood is a matter of growing concern. In several European countries, this utilisation is governed by regulations and is dependent on the contents of certain trace elements and organic compounds. Thus, for decisionmaking with respect to waste wood management (recycling or combustion), reliable analytical data are needed and, due to their great economic and environmental impact, must be assured by appropriate quality control. To support the improvement in quality assurance in waste wood analysis, for the first time, a wood reference material was certified for its mass fractions of arsenic, cadmium, chromium, copper, lead, mercury, and pentachlorophenol (PCP). These analytes were selected because they represent typical constituents of wood preservatives most widely used in the past. Material preparation and testing of homogeneity and stability were carried out by BAM Federal Institute for Materials Research and Testing. The certification measurements were performed involving selected laboratories with documented expertise in the field of waste wood analysis. The certified values and their corresponding uncertainties were assigned in full compliance with the requirements of ISO Guide 35. The certified mass fractions and their expanded uncertainties (k/i> = 2) are as follows: (3.1 ± 0.5) mg/kg for As, (3.02 ± 0.24) mg/kg for Cd, (36.4 ± 2.6) mg/kg for Cr, (22.9 ± 1.7) mg/kg for Cu, (0.60 ± 0.14) mg/kg for Hg, (39 ± 4) mg/kg for Pb, and (7.9 ± 0.6) mg/kg for PCP. The certified material is available as European Reference Material ERM®-CD100. KW - Waste wood KW - Trace elements KW - Pentachlorophenol KW - Certification KW - European reference material PY - 2010 DO - https://doi.org/10.1007/s00769-010-0699-0 SN - 0949-1775 SN - 1432-0517 VL - 15 IS - 11 SP - 613 EP - 619 PB - Springer CY - Berlin AN - OPUS4-22392 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Krysell, M. A1 - Becker, Roland A1 - Wegener, J. W. A1 - Buge, Hans-Gerhard T1 - Certified reference materials for organic contaminants in sewage sludge - a feasibility study JF - Accreditation and quality assurance N2 - As an answer to the re-evaluation of the European sludge directive, two novel reference materials for organic components in municipal sludge have been produced and test certified for AOX (absorbable organic halogens), PAH (polycyclic aromatic hydrocarbons), NPE (nonylphenol and nonylphenolethoxylates), DEHP (di(2-ethylhexyl)phthalate), bisphenol A, and BFR (brominated flame retardants). The materials were prepared from raw sludge without spiking or mixing of different sludges. The study demonstrated that the technique for the preparation of a suitable reference material, sufficiently homogenous and stable, and with concentration levels that answer the needs of the laboratories and the relevant authorities, can now be presented in detail. The results, furthermore, show there is a need for method validation and standardisation of the measurements of NPEs and certain BFR congeners, and that the development of the laboratory structure in Europe, with fewer and more specialised laboratories, might become a major obstacle when trying to find a sufficient number of laboratories being appropriately proficient for this kind of study in the future. KW - Organic pollutants KW - Municipal sludge KW - CRM KW - AOX KW - BPA KW - PAH KW - DEHP KW - NPE KW - BFR PY - 2008 DO - https://doi.org/10.1007/s00769-008-0431-5 SN - 0949-1775 SN - 1432-0517 VL - 13 IS - 10 SP - 553 EP - 562 PB - Springer CY - Berlin AN - OPUS4-18362 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Weber, M. A1 - Becker, Roland A1 - Durmaz, V. A1 - Köppen, Robert T1 - Classical hybrid Monte-Carlo simulation of the interconversion of hexabromocyclododecane stereoisomers JF - Molecular simulation KW - HBCD KW - Isomerisation KW - Statistical thermodynamics KW - Kinetics PY - 2008 DO - https://doi.org/10.1080/08927020802208968 SN - 0892-7022 SN - 1029-0435 VL - 34 IS - 6-7 SP - 727 EP - 736 PB - Gordon and Breach CY - New York, NY AN - OPUS4-18261 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -