TY - GEN A1 - Rurack, Knut A1 - Martínez-Mánez, Ramon A1 - Sancenón, F. A1 - Descalzo López, Ana Belén ED - Rurack, Knut ED - Martínez-Mánez, Ramon T1 - Biomimetically inspired signaling KW - Bindungstaschen KW - Biochemie KW - Biomimetika KW - Chromatophore KW - Gold KW - Hybridmaterialien KW - Ionenkanäle KW - Metalloregulation KW - Nanopartikel KW - Quantenpunkte KW - Sensorik KW - Silica KW - Supramolekulare Chemie KW - Verdrängungsassays PY - 2010 SN - 978-0-470-37621-8 SP - 549 EP - 580 PB - John Wiley & Sons CY - Hoboken, New Jersey, USA AN - OPUS4-21960 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Climent Terol, Estela A1 - Biyikal, Mustafa A1 - Gawlitza, Kornelia A1 - Dropa, T. A1 - Urban, M. A1 - Costero, A. M. A1 - Martínez-Mánez, Ramon A1 - Rurack, Knut T1 - A rapid and sensitive strip-based quick test for nerve agents Tabun, Sarin, and Soman using BODIPY-modified silica materials N2 - Test strips that in combination with a portable fluorescence reader or digital camera can rapidly and selectively detect chemical warfare agents (CWAs) such as Tabun (GA), Sarin (GB), and Soman (GD) and their simulants in the gas phase have been developed. The strips contain spots of a hybrid indicator material consisting of a fluorescent BODIPY indicator covalently anchored into the channels of mesoporous SBA silica microparticles. The fluorescence quenching response allows the sensitive detection of CWAs in the μg m−3 range in a few seconds. KW - Chemical warfare agents KW - Fluorescence KW - Hybrid sensor materials KW - Nerve gases KW - Test strip analysis PY - 2016 DO - https://doi.org/10.1002/chem.201601269 SN - 0947-6539 SN - 1521-3765 VL - 22 IS - 32 SP - 11138 EP - 11142 PB - Wiley CY - Online Library AN - OPUS4-37063 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Biyikal, Mustafa A1 - Hecht, Mandy A1 - Martínez-Mánez, Ramon A1 - Rurack, Knut A1 - Sancenón, F. ED - Gale, P.A. ED - Steed, J.W. T1 - Supramolecular hybrid nanomaterials as prospective sensing platforms N2 - Supramolecular interactions are vital processes in many chemical sensors, biochemical assays, and other analytical detection schemes. On the background of the current, rapidly developing, and constantly changing requirements for (bio)analytical techniques, the classical molecular host is increasingly overburdened to accomplish a specific analytical task with the desired selectivity and sensitivity. Instead, other signaling strategies have to be conceived that overcome the limits in signal output, dynamic range, or compound targeting, which are imminent to various traditional methods. A very promising approach is the combination of concepts of supramolecular chemistry with nanostructured or nanoscopic inorganic materials, that is, the development of hybrid sensor materials. Such hybrids often lead to improved functionality and enhanced performance, and the present chapter discusses the contributory features in relation to the major aspects, which are related to the enhanced coordination by the preorganization of binding sites, signal amplification by the preorganization on surfaces, aggregation‐mediated signaling, surface‐modification‐based signaling, the tuning of selectivity through polarity and size, and gated signaling. KW - Supramolekulare Chemie KW - Optische Sonden KW - Nanotechnologie KW - Hybridmaterialien KW - Fluorescence KW - Hybrid nanomaterials KW - Optical sensors KW - Redox sensors KW - Supramolecular chemistry PY - 2012 SN - 978-0-470-74640-0 DO - https://doi.org/10.1002/9780470661345.smc199 SP - 3669 EP - 3698 PB - John Wiley & Sons AN - OPUS4-26118 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Climent Terol, Estela A1 - Gröninger, Delia A1 - Hecht, Mandy A1 - Walter, Astrid A1 - Martínez-Mánez, Ramon A1 - Weller, Michael G. A1 - Sancenón, F. A1 - Amorós, P. A1 - Rurack, Knut T1 - Selective, sensitive, and rapid analysis with lateral-flow assays based on antibody-gated dye-delivery systems: The example of triacetone triperoxide N2 - Set them free: Brightly fluorescent indicators that are loaded into mesoporous silica nanoparticle carriers, capped with bulky antibodies, are released into the lateral flow of a test strip upon analyte arrival. Integration of the system into a rapid, simple flow test with fluorescence readout is applied for the selective and sensitive determination of the presence of triacetone triperoxide (TATP) as a prototype small-molecule analyte (see figure). KW - Farbstoffe KW - Sprengstoffe KW - Fluoreszenz KW - Immunoassays KW - Mesoporöse Materialien PY - 2013 DO - https://doi.org/10.1002/chem.201300031 SN - 0947-6539 SN - 1521-3765 VL - 19 IS - 13 SP - 4117 EP - 4122 PB - Wiley-VCH Verl. CY - Weinheim AN - OPUS4-29508 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -