TY - JOUR A1 - Bergmann, A. A1 - Grosser, H. A1 - Graf, B. A1 - Uhlmann, E. A1 - Rethmeier, Michael A1 - Stark, R. T1 - Additive Prozesskette zur Instandsetzung von Bauteilen - Aufbau, Reparatur und Modellbildung N2 - Komplexe Bauteile ohne Fügestellen sind die Spezialität additiver Verfahren. Immer deutlicher wird der Wert dieser Technologie für den Turbomaschinenbau, etwa bei der Fertigung von Turbinenschaufeln mit inneren Kühlstrukturen. Wichtig für vorbildgetreue Turbinenkomponenten: Die Technologie ermöglicht die Fertigung von Freiformen und Hinterschnitten, von außen- und innenliegenden filigranen, komplexen Strukturen als Einzelteil - und das in einem einzigen Arbeitsschritt. Des Weiteren benötigen additive Verfahren keine formgebenden Werkzeuge und weisen demnach kürzere Prozessketten im Vergleich zu konventionellen Herstellungsverfahren auf. Wirtschaftliche Vorteile kommen vor allem bei kleinen Losgrößen und Bauteilabmessungen zur Geltung. In diesem Artikel werden am Beispiel einer Turbinenschaufel Schlüsseltechnologien einer additiven Prozesskette gezeigt. Zunächst erfolgt die additive Fertigung einer Turbinenschaufel mittels Selective Laser Melting (SLM). Das Verfahren ermöglicht die Integration innenliegender Kühlkanäle. An dieser Schaufel wird anschließend mittels Laser-PulverAuftragschweißen (LPA) die Reparatur unterschiedlicher Beschädigungen demonstriert. Im nächsten Schritt der Prozesskette bietet ein optischer 3D-Scan der Schaufel die Möglichkeit zur Qualitätskontrolle und zum Vergleich der Bauteilabmessungen mit der Sollgeometrie. PY - 2013 DO - https://doi.org/10.1002/latj.201390021 SN - 1613-7728 SN - 1863-9119 VL - 10 IS - 2 SP - 31 EP - 35 PB - Wiley-VCH CY - Weinheim AN - OPUS4-28066 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Uhlmann, E. A1 - Rethmeier, Michael A1 - Graf, B. A1 - Kersting, R. A1 - Bergmann, A. T1 - Flexible manufacturing with an additive process chain design, production and surface finish N2 - The industrial demand for flexible and innovative manufacturing technologies is continuously increasing. These technologies have to be sustainable and resource-efficient, and have to allow the production of long-life capital goods. Consequently, the additive processes gain in importance as they offer an enormous potential of application, especially for the turbomachinery industry. In order to use additive manufacturing technologies in industrial applications, it is necessary to consider the complete process chain, including all necessary pre- and postprocessing. Although additive manufacturing is increasingly covered in scientific research, the linking between this technology and conventional industrial processes is rarely described. T2 - ASPE Spring topical meeting - Achieving precision tolerances in additive manufacturing CY - Raleigh, NC, USA DA - 26.04.2015 PY - 2015 SN - 978-1-887706-67-4 SP - Session I, 5 EP - 9 AN - OPUS4-34855 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Li, Changchao A1 - Jin, Ling N. A1 - Bank, Michael S. A1 - Fan, Chunlan A1 - Gillings, Michael R. A1 - Zhao, Tingting A1 - Han, Yong A1 - Chen, Tian A1 - Gao, Meng A1 - Zhu, Dong A1 - Chen, Qinglin A1 - Zhu, Guibing A1 - Wang, Jie A1 - Wang, Lei A1 - Liu, Jian A1 - Yuan, Xianzheng A1 - Huang, Qishen A1 - Wang, Xiaofei A1 - Jahnke, Annika A1 - Brahney, Janice A1 - Allen, Steve A1 - Arp, Hans Peter H. A1 - Oberbeckmann, Sonja A1 - Bergmann, Melanie A1 - Pointing, Stephen B. A1 - Zhang, Daizhou A1 - Rillig, Matthias C. T1 - Potential planetary health impacts of the airborne plastisphere N2 - Microplastics are a ubiquitous yet long-overlooked component of airborne particulate matter. The surface of these plastic particles provides a unique niche for microorganisms, collectively known as the plastisphere. The plastisphere in aquatic and terrestrial ecosystems harbors microbial communities with distinct compositions, structures, and functional profiles, posing potential planetary health risks. The characteristics, fate, and impacts of the microbiome associated with airborne microplastics, however, remain largely unknown. In this review, we fill the knowledge gaps by exploring how airborne microplastics serve as key habitats for microorganisms and the potential planetary health implications. We show that microplastics are expected to carry and sustain microorganisms over long distances and timescales in air, potentially dispersing pathogens, antibiotic-resistance genes, and other bioactive agents across ecosystems. These interactions may perturb ecological processes and biological health on a planetary scale. Interdisciplinary research and innovative methodologies are urgently required to better understand and mitigate the airborne plastisphere risks. KW - Microplastics KW - Microbiome KW - Plastisphere PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-645551 DO - https://doi.org/10.1016/j.oneear.2025.101446 SN - 2590-3322 VL - 8 IS - 10 SP - 1 EP - 17 PB - Elsevier B.V. AN - OPUS4-64555 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Drogan, D. A1 - Sheldrick, A. J. A1 - Schütze, M. A1 - Knüppel, S. A1 - Andersohn, F. A1 - di Giuseppe, R. A1 - Herrmann, Bianca A1 - Willich, S. N. A1 - Garbe, E. A1 - Bergmann, M. M. A1 - Boeing, H. A1 - Weikert, C. T1 - Alcohol consumption, genetic variants in alcohol deydrogenases, and risk of cardiovascular diseases: A prospective study and meta-analysis N2 - Objective: First, to investigate and compare associations between alcohol consumption and variants in alcohol dehydrogenase (ADH) genes with incidence of cardiovascular diseases (CVD) in a large German cohort. Second, to quantitatively summarize available evidence of prospective studies on polymorphisms in ADH1B and ADH1C and CVD-risk. Methods: We conducted a case-cohort study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam cohort including a randomly drawn subcohort (n = 2175) and incident cases of myocardial infarction (MI; n = 230) or stroke (n = 208). Mean follow-up time was 8.2±2.2 years. The association between alcohol consumption, ADH1B or ADH1C genotypes, and CVD-risk was assessed using Cox proportional hazards regression. Additionally, we report results on associations of variants in ADH1B and ADH1C with ischemic heart disease and stroke in the context of a meta-analysis of previously published prospective studies published up to November 2011. Results: Compared to individuals who drank >0 to 6 g alcohol/d, we observed a reduced risk of MI among females consuming >12 g alcohol/d (HR = 0.31; 95% CI: 0.10–0.97) and among males consuming >24 to 60 g/d (HR = 0.57; 95% CI: 0.33–0.98) or >60 g alcohol/d (HR = 0.30; 95% CI: 0.12–0.78). Stroke risk was not significantly related to alcohol consumption >6 g/d, but we observed an increased risk of stroke in men reporting no alcohol consumption. Individuals with the slowcoding ADH1B*1/1 genotype reported higher median alcohol consumption. Yet, polymorphisms in ADH1B or ADH1C were not significantly associated with risk of CVD in our data and after pooling results of eligible prospective studies [ADH1B*1/1: RR = 1.35 (95% CI: 0.98–1.88; p for heterogeneity: 0.364); ADH1C*2/2: RR = 1.07 (95% CI: 0.90–1.27; p for heterogeneity: 0.098)]. Conclusion: The well described association between alcohol consumption and CVD-risk is not reflected by ADH polymorphisms, which modify the rate of ethanol oxidation. KW - Coronary heart disease KW - Myocardial infarction KW - Dehydrogenase KW - Genotypes KW - Relative validity KW - Drinking habits KW - EPIC-Potsdam Study KW - German part KW - Case cohort KW - Stroke KW - Reproducibility PY - 2012 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-633710 DO - https://doi.org/10.1371/journal.pone.0032176 SN - 1932-6203 N1 - The recruitment phase of the EPIC-Potsdam Study was supported by the Federal Ministry of Science, Germany (01 EA 9401), and the European Union (SOC 95201408 05F02). The follow-up was supported by the German Cancer Aid (70-2488-Ha I) and the European Community (SOC 98200769 05F02). VL - 7 IS - 2 SP - 1 EP - 11 PB - Public Library of Science (PLoS) CY - San Francisco, California, US AN - OPUS4-63371 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ortel, Erik A1 - Polte, J. A1 - Bernsmeier, D. A1 - Eckhardt, B. A1 - Paul, B. A1 - Bergmann, A. A1 - Strasser, P. A1 - Emmerling, Franziska A1 - Kraehnert, R. T1 - Pd/TiO2 coatings with template-controlled mesopore structure as highly active hydrogenation catalyst N2 - Micro-structured reactors offer excellent mass and heat transport capabilities and can therefore sustain very high reaction rates and space–time-yields also for highly exothermic catalytic reactions. However, such high rates cannot be reached when the reactors are coated or filled with conventional catalysts powders. We present a strategy for the direct synthesis of highly active wall-coated supported catalysts via co-deposition of a pore template (here micelles formed from PEO-b-PPO-b-PEO) and a precursors for the metal oxide (TiCl4) along with a compatible precursor for the active metal (PdCl2). The obtained catalytic coatings possess a template-controlled open pore structure and excellent mechanical stability. Moreover, the active metal is highly dispersed and well-distributed across the coating also at high Pd loadings. The corresponding high activity along with rapid mass transfer enabled by the open pore system results in the best space–time-yields in the gas-phase hydrogenation of butadiene reported so far in literature for a supported catalyst. KW - Titanium oxide films KW - Palladium nanoparticle KW - Wall-coated supported catalysts KW - Template-controlled mesoporous materials KW - Hydrogenation of 1,3-butadiene PY - 2015 DO - https://doi.org/10.1016/j.apcata.2014.12.044 SN - 0926-860X SN - 1873-3875 VL - 493 SP - 25 EP - 32 PB - Elsevier CY - Amsterdam AN - OPUS4-32465 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Meißner, T. A1 - Bergmann, R. A1 - Oswald, J. A1 - Rode, K. A1 - Stephan, H. A1 - Richter, W. A1 - Zänker, H. A1 - Kraus, Werner A1 - Emmerling, Franziska A1 - Reck, Günter T1 - Chitosan-encapsulated Keggin anion [Ti2W10PO40]7-.Synthesis, characterization and cellular uptake studies N2 - The Keggin type polyoxotungstate [Ti2W10PO40]7- forms stable associates with the biopolymer chitosan in the nanometer size range. The cluster compound crystallizes from aqueous solution as K4H3[Ti2W10PO40] · 15H2O having a tetragonal structure. Both, the cluster compound and the chitosan/[Ti2W10PO40] associates show a high hydrolytic stability at pH 7.4. The associates formed between the cluster anion [Ti2W10PO40]7- with the polyaminosaccharide chitosan have been characterized by photon correlation spectroscopy, scanning electron microscopy, filtration, centrifugation and zeta potential measurements. The size of the associates formed is in the range of ca. 5×101 to 5×102 nm. These particles have a defined stoichiometry with 5–6 cluster anions bound per molecule chitosan. The isoelectric point determined by zeta potential measurements was found for a cluster anion to chitosan molar ratio of 5.5, indicating the charge neutralization between protonated chitosan and [Ti2W10PO40]7- anions. Cellular uptake studies with [Ti2W10PO40]7- using tumor cell lines FaDu (human squamous carcinoma) and HT-29 (human adenocarcinoma) showed that the tungsten amount inside the cells is remarkably enhanced in the presence of chitosan. KW - Cluster compound KW - Keggin structure KW - Bipolymer KW - Chitosan PY - 2006 DO - https://doi.org/10.1007/s11243-006-0035-z SN - 0340-4285 SN - 1572-901X VL - 31 IS - 5 SP - 603 EP - 610 PB - Springer CY - Dordrecht AN - OPUS4-12568 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -