TY - JOUR A1 - Gaul, Holger A1 - Weber, Gert A1 - Rethmeier, Michael T1 - Evaluation of fatigue crack propagation in spot welded joints by stiffness measurements N2 - Resistance spot welded joints made of two advanced high strength steels (AHSS) and one high strength steel (HSS) were examined. In the high cycle fatigue regime tests were realised for one loading condition, and the load and the displacement were measured. From the load and displacement range, the stiffness was calculated and in situ normalised to its value after 1000 cycles. It was thus possible to use the normalised stiffness evaluated during the experiment as failure criterion for the fatigue test of resistance spot welded joints. In order to evaluate this failure criterion, fatigue cracks were produced in the three different steel grades mentioned above according to user-specified levels of the normalised stiffness. It was found that the fatigue crack area increases linearly and the through-sheet-thickness crack length exponentially with decreasing stiffness. The comparison of the fatigue crack propagation during the fatigue test of the three different tested base metals showed very similar values. The comparability of fatigue tests performed on spot welded joints might thus be improved by the in situ evaluated stiffness as a failure criterion. This can be also used in further work to verify results of computer simulations of the stress intensity factor at spot welds with the help of experimental results. KW - Resistance spot welding KW - Fatigue KW - Frequency KW - Stiffness KW - Advanced high strength steels KW - Crack growth PY - 2011 DO - https://doi.org/10.1016/j.ijfatigue.2010.12.005 SN - 0142-1123 VL - 33 IS - 5 SP - 740 EP - 745 PB - Elsevier CY - Oxford AN - OPUS4-22207 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Brauser, Stephan A1 - Weber, Gert A1 - Rethmeier, Michael T1 - Potenzial optischer Dehnungsfeldmessung zur Charakterisierung der Eigenschaften von Widerstandspunktschweißverbindungen N2 - Die Ermittlung lokaler Werkstoffkennwerte im Schweißbereich ist für die Auslegung sicherheitsrelevanter Bauteile insbesondere durch Finite-Elemente-Berechnungen von großer Bedeutung. Konventionelle Prüfmethoden können lediglich globale Kennwerte bereitstellen, die jedoch gerade für die Berechnung widerstandspunktgeschweißter Bauteile häufig nicht ausreichen, da diese durch das Vorliegen örtlich eng begrenzter Fügezonen gekennzeichnet sind. Moderne Prüfmethoden wie die optische Dehnungsfeldmessung ermöglichen hingegen eine orts- und zeitkonkrete Bestimmung der Werkstoffkenndaten. Um das Potenzial optischer Dehnungsfeldmessungen für das Charakterisieren des lokalen Werkstoffverhaltens von Punktschweißverbindungen zu ermitteln, wurden Scherzugversuche sowie Zugversuche an widerstandspunktgeschweißten hochfesten Stählen durchgeführt. Die Ergebnisse zeigen das hohe Potenzial dieses Verfahrens sowohl für die Quantifizierung des lokalen Dehnungsverhaltens im Fügebereich als auch für die Ermittlung lokaler Werkstoffkenndaten. PY - 2010 SN - 0036-7184 VL - 62 IS - 9 SP - 496 EP - 500 PB - Verl. für Schweißen u. Verwandte Verfahren, DVS-Verl. CY - Düsseldorf AN - OPUS4-22163 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Pimienta, Pierre A1 - McNamee, Robert A1 - Hager, Izabela A1 - Mróz, Katarzyna A1 - Boström, Lars A1 - Mohaine, Siyimane A1 - Huang, Shan-Shan A1 - Mindeguia, Jean-Christophe A1 - Robert, Fabienne A1 - Davie, Colin A1 - Felicetti, Roberto A1 - Miah, Md Jihad A1 - Lion, Maxime A1 - Lo Monte, Francesco A1 - Ozawa, Mitsuo A1 - Rickard, Ieuan A1 - Sideris, Kosmas A1 - Alonso, Maria Cruz A1 - Millard, Alain A1 - Jumppanen, Ulla-Maija A1 - Bodnarova, Lenka A1 - Bosnjak, Josipa A1 - Dal Pont, Stefano A1 - Dao, Vinh A1 - Dauti, Dorjan A1 - Dehn, Frank A1 - Hela, Rudolf A1 - Hozjan, Tomaz A1 - Juknat, Michael A1 - Kirnbauer, Johannes A1 - Kolsek, Jerneja A1 - Korzen, Manfred A1 - Lakhani, Hitesh A1 - Maluk, Cristian A1 - Meftah, Fekri A1 - Moreau, Bérénice A1 - Pesavento, Francesco A1 - Pham, Duc Toan A1 - Pistol, Klaus A1 - Correia Rodrigues, Joao Paulo A1 - Roosefid, Mohsen A1 - Schneider, Martin A1 - Sharma, Umesh Kumar A1 - Stelzner, Ludwig A1 - Weber, Benedikt A1 - Weise, Frank T1 - Recommendation of RILEM TC 256-SPF on the method of testing concrete spalling due to fire: material screening test N2 - The recommendation is based on the coauthors’ work organized by the RILEM TC 256-SPF ‘‘Spalling of concrete due to fire: testing and modelling’’. The Committee has defined two types of screening tests for characterization of concrete propensity to fire spalling: Material screening tests and Product screening tests. Definitions of both types of tests are given in the paper. The following recommendations apply to Material screening tests. The material screening tests described in these recommendations are a set of minimum requirements to test concrete spalling propensity (for example, the minimal specimen size). This document covers the aspects of concrete characterization, specimen geometries, storage conditions, test methods and measured parameters. KW - Concrete KW - Fire Spalling KW - Screening tests KW - High temperature PY - 2023 DO - https://doi.org/10.1617/s11527-023-02202-z VL - 56 IS - 9 SP - 1 EP - 12 PB - Springer Science and Business Media LLC AN - OPUS4-60635 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Reinmuth-Selzle, K. A1 - Kampf, C. J. A1 - Lucas, K. A1 - Lang-Yona, N. A1 - Fröhlich-Nowoisky, J. A1 - Shiraiwa, M. A1 - Lakey, P. S. J. A1 - Lai, S. A1 - Liu, F. A1 - Kunert, A. T. A1 - Ziegler, K. A1 - Shen, F. A1 - Sgarbanti, R. A1 - Weber, B. A1 - Bellinghausen, I. A1 - Saloga, J. A1 - Weller, Michael G. A1 - Duschl, A. A1 - Schuppan, D. A1 - Pöschl, U. T1 - Air pollution and climate change effects on allergies in the anthropocene: Abundance, interaction, and modification of allergens and adjuvants N2 - Air pollution and climate change are potential drivers for the increasing burden of allergic diseases. The molecular mechanisms by which air pollutants and climate parameters may influence allergic diseases, however, are complex and elusive. This article provides an overview of physical, chemical and biological interactions between air pollution, climate change, allergens, adjuvants and the immune system, addressing how these interactions may promote the development of allergies. We reviewed and synthesized key findings from atmospheric, climate, and biomedical research. The current state of knowledge, open questions, and future research perspectives are outlined and discussed. The Anthropocene, as the present era of globally pervasive anthropogenic influence on planet Earth and, thus, on the human environment, is characterized by a strong increase of carbon dioxide, ozone, nitrogen oxides, and combustion- or traffic-related particulate matter in the atmosphere. These environmental factors can enhance the abundance and induce chemical modifications of allergens, increase oxidative stress in the human body, and skew the immune system toward allergic reactions. In particular, air pollutants can act as adjuvants and alter the immunogenicity of allergenic proteins, while climate change affects the atmospheric abundance and human exposure to bioaerosols and aeroallergens. To fully understand and effectively mitigate the adverse effects of air pollution and climate change on allergic diseases, several challenges remain to be resolved. Among these are the identification and quantification of immunochemical reaction pathways involving allergens and adjuvants under relevant environmental and physiological conditions. KW - Allergie KW - Klimaveränderung KW - Luftverschmutzung KW - Partikel KW - Ozon KW - Stickoxide KW - Allergene KW - Adjuvantien KW - PALM KW - DAMP PY - 2017 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-404531 DO - https://doi.org/10.1021/acs.est.6b04908 SN - 1520-5851 SN - 0013-936X VL - 51 IS - 8 SP - 4119 EP - 4141 PB - American Chemical Society (ACS) CY - Washington AN - OPUS4-40453 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - BOOK A1 - Maiwald, Michael A1 - Bassler, M. A1 - Deilmann, M. A1 - Ens, W. A1 - Frenzel, F. A1 - Gerlach, M. A1 - Großmann, J. A1 - Grümbel, F. A1 - Heisterkamp, M. A1 - Kaiser, U. A1 - Lambrecht, A. A1 - Ohlenkamp, R. A1 - Pötter, T. A1 - Pyka, P. A1 - Roos, E. A1 - Schmidt, A. A1 - Schünemann, U. A1 - Theuer, M. A1 - Tukle, A. A1 - Weber, N. T1 - Technologie-Roadmap „Prozess-Sensoren 2027+“ N2 - Die Technologie-Roadmap „Prozess-Sensoren 2027+“ ist eine Weiterentwicklung vorgängiger Technologie-Roadmaps. Im Zentrum dieser Roadmaps stehen Sensoren zur Erfassung von physikalischen und chemischen Messgrößen mittels spezifischer und unspezifischer Messverfahren, die zur Steuerung und dem besseren Verständnis von Prozessen dienen. Die Roadmap fasst die gemeinsame Technologie- und Marktsicht von Anwendern, Herstellern und Forschungseinrichtungen im Bereich Prozess-Sensorik in der verfahrenstechnischen Industrie zusammen. Sie beschreibt die wesentlichen Trends im Bereich Prozess-Sensorik und künftige Handlungsbedarfe für Hersteller, Anwender sowie für Einrichtungen der Forschung und Lehre. Für die aktuellen und zukünftigen Anforderungen an Prozess-Sensoren werden 19 Thesen formuliert. Die Thesen basieren auf den Thesen der vorangegangenen Roadmaps, wobei die aus heutiger Sicht erforderlichen Anpassungen, Ergänzungen und teilweise auch Streichungen vorgenommen wurden. Die Thesen sind in 5 Themencluster eingeordnet. Digitalisierung und Nachhaltigkeit sind übergreifende Kernthemen der künftigen Entwicklung. KW - Technologie-Roadmap Prozess-Sensoren KW - Prozessindustrie KW - Prozessanalytik KW - Sensorik KW - Digitalisierung KW - NAMUR PY - 2021 SP - 1 EP - 63 AN - OPUS4-53741 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Kern, Simon A1 - Wander, Lukas A1 - Meyer, Klas A1 - Guhl, Svetlana A1 - Gottu Mukkula, A. R. A1 - Holtkamp, M. A1 - Salge, M. A1 - Fleischer, C. A1 - Weber, N. A1 - Engell, S. A1 - Paul, Andrea A1 - Pereira Remelhe, M. A1 - Maiwald, Michael T1 - Flexible automation with compact NMR spectroscopy for continuous production of pharmaceuticals N2 - Modular plants using intensified continuous processes represent an appealing concept for the production of pharmaceuticals. It can improve quality, safety, sustainability, and profitability compared to batch processes; besides, it enables plug-and-produce reconfiguration for fast product changes. To facilitate this flexibility by real-time quality control, we developed a solution that can be adapted quickly to new processes and is based on a compact nuclear magnetic resonance (NMR) spectrometer. The NMR sensor is a benchtop device enhanced to the requirements of automated chemical production including robust evaluation of sensor data. Beyond monitoring the product quality, online NMR data was used in a new iterative optimization approach to maximize the plant profit and served as a reliable reference for the calibration of a near-infrared (NIR) spectrometer. The overall approach was demonstrated on a commercial-scale pilot plant using a metal-organic reaction with pharmaceutical relevance. KW - NMR Spectroscopy KW - NIR Spectroscopy KW - Real-time process monitoring KW - Real-time quality control KW - Continuous processes KW - CONSENS KW - Data Fusion PY - 2019 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-480623 DO - https://doi.org/10.1007/s00216-019-01752-y SN - 1618-2642 SN - 1618-2650 VL - 411 IS - 14 SP - 3037 EP - 3046 PB - Springer Nature CY - Heidelberg AN - OPUS4-48062 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Kern, Simon A1 - Wander, Lukas A1 - Meyer, Klas A1 - Guhl, Svetlana A1 - Gottu Mukkula, A. R. A1 - Holtkamp, M. A1 - Salge, M. A1 - Fleischer, C. A1 - Weber, N. A1 - Engell, S. A1 - Paul, Andrea A1 - King, R. A1 - Maiwald, Michael T1 - Raw data of pilot plant runs for CONSENS project (Case study 1) N2 - In case study one of the CONSENS project, two aromatic substances were coupled by a lithiation reaction, which is a prominent example in pharmaceutical industry. The two aromatic reactants (Aniline and o-FNB) were mixed with Lithium-base (LiHMDS) in a continuous modular plant to produce the desired product (Li-NDPA) and a salt (LiF). The salt precipitates which leads to the formation of particles. The feed streams were subject to variation to drive the plant to its optimum. The uploaded data comprises the results from four days during continuous plant operation time. Each day is denoted from day 1-4 and represents the dates 2017-09-26, 2017-09-28, 2017-10-10, 2017-10-17. In the following the contents of the files are explained. KW - Process Analytical Technology KW - Multivariate Data Analysis KW - Nuclear Magnetic Resonance KW - Near Infrared Spectroscopy KW - Continuous Manufacturing KW - CONSENS PY - 2018 DO - https://doi.org/10.5281/zenodo.1438233 PB - Zenodo CY - Geneva AN - OPUS4-48063 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -