TY - GEN A1 - Alexander, I. A1 - Braun, H.-J. A1 - Dettmann, T. A1 - Fimmen, H. A1 - Haberkamp, H. A1 - Katz, H. A1 - Krischok, Frank A1 - Otremba, Frank A1 - Pötzsch, Klaus-Michael A1 - Zentgraf, R. A1 - Putzschke, M. T1 - Bericht über den Ablauf und die Ursachen der Havarie des Tankmotorschiffes 'Waldhof' am 13. Januar 2011 auf dem Mittelrhein (Rhein-km 553,75) KW - Schiffshavarie KW - Gefahrgut-Tankschiff KW - Schwimmstabilität PY - 2013 IS - S-312.4/016 SP - 1 EP - 224 AN - OPUS4-27729 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Weise, Frank A1 - Patitz, G. A1 - Redmer, Bernhard A1 - Hübner, M. A1 - Haamkens, Frank A1 - Ewert, Uwe ED - Wittmann, F. H. ED - Gerdes, A. T1 - Kombination zerstörungsfreier Prüfverfahren zur Strukturaufklärung in antiken Baudenkmälern T2 - MSR-VI ; 6th International Conference on Materials Science and Restoration ; 6th Internationales Kolloquium Werkstoffwissenschaften und Bauinstandsetzen CY - Karlsruhe, Deutschland DA - 2003-09-16 KW - Antikes Baudenkmal KW - Strukturaufklärung KW - Lokalisierung von metallischen Einbauteilen und Hohlstellen KW - Kombinierter Einsatz zerstörungsfreier Prüfverfahren KW - Radar KW - Videoskopie KW - Radiografie PY - 2003 SN - 3-931681-76-9 IS - 6 SP - 359 EP - 370 PB - Aedificatio-Verl. CY - Freiburg AN - OPUS4-2817 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Weise, Frank A1 - Patitz, G. A1 - Redmer, Bernhard A1 - Hübner, M. A1 - Haamkens, Frank ED - Patitz, G. T1 - Kombination zerstörungsfreier Prüfverfahren zur Strukturaufklärung in antiken Baudenkmälern KW - Baudenkmäler KW - Strukturaufklärung KW - Zerstörungsfreie Prüfung KW - Videoskopie KW - Radar KW - Radiografie PY - 2004 SN - 3-8167-6443-6 N1 - Serientitel: Monudocthema – Series title: Monudocthema IS - 1 SP - 117 EP - 125 PB - Fraunhofer-IRB-Verl. CY - Stuttgart AN - OPUS4-4821 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Altmann, Korinna A1 - Portela, Raquel A1 - Barbero, Francesco A1 - Breuninger, Esther A1 - Camassa, Laura Maria Azzurra A1 - Velickovic, Tanja Cirkovic A1 - Charitidis, Costas A1 - Costa, Anna A1 - Fadda, Marta A1 - Fengler, Petra A1 - Fenoglio, Ivana A1 - Giovannozzi, Andrea M. A1 - Haugen, Øyvind Pernell A1 - Kainourgios, Panagiotis A1 - von der Kammer, Frank A1 - Kirchner, Markus J. A1 - Lomax-Vogt, Madeleine A1 - Lujic, Tamara A1 - Milczewski, Frank A1 - Moussawi, Mhamad Aly A1 - Ortelli, Simona A1 - Parac-Vogt, Tatjana N. A1 - Potthoff, Annegret A1 - Reinosa, Julian J. A1 - Röschter, Sophie A1 - Sacco, Alessio A1 - Wimmer, Lukas A1 - Zanoni, Ilaria A1 - Dailey, Lea Ann T1 - Characterizing nanoplastic suspensions of increasing complexity: Inter-laboratory comparison of size measurements using dynamic light scattering N2 - Understanding the potential human health risks associated with micro- and nanoplastic exposure is currently a priority research area. Nanoplastic toxicity studies are complicated by the lack of available, well-characterized test and reference materials. Further, many nanoplastic test materials are inherently more polydisperse and heterogenous in shape compared to polystyrene beads, making accurate and representative size distribution measurements particularly challenging. The aim of this study was to conduct an inter-laboratory comparison of dynamic light scattering measurements, the most commonly used particle sizing method for nanomaterials. Using a published standard operating procedure, size measurements in water and a standardized cell culture medium (CCM) were generated for spherical, carboxy-functionalized polystyrene nanoparticles (PS-COOH; 50 nm; benchmark material), and for increasingly complex in-house produced spherical poly(ethylene terephthalate) (nanoPET) and irregular shaped polypropylene (nanoPP) test materials. The weighted mean of hydrodynamic diameters of PS-COOH dispersed in water (55 ± 5 nm) showed moderate variation between labs (coefficient of variation, CV = 8.2%) and were similar to literature reports. Measurements of nanoPET (82 ± 6 nm) and nanoPP (182 ± 12 nm) in water exhibited similar CV values (nanoPET: 7.3% and nanoPP; 6.8%). Dispersion of PS-COOH and nanoPET in CCM increased the CV to 15.1 and 14.2%, respectively, which is lower than literature reports (CV = 30%). We conclude with a series of practical recommendations for robust size measurements of nanoplastics in both water and complex media highlighting that strict adherence to a standard operating procedure is required to prevent particle agglomeration in CCM KW - Nanoplastics KW - Reference materials KW - Polypropylene PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-644571 DO - https://doi.org/10.1039/d5en00645g SN - 2051-8153 SP - 1 EP - 15 PB - Royal Society of Chemistry (RSC) CY - Cambridge AN - OPUS4-64457 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Altmann, Korinna A1 - Portela, Raquel A1 - Barbero, Francesco A1 - Breuninger, Esther A1 - Camassa, Laura Maria Azzurra A1 - Cirkovic Velickovic, Tanja A1 - Charitidis, Costas A1 - Costa, Anna A1 - Fadda, Marta A1 - Fengler, Petra A1 - Fenoglio, Ivana A1 - Giovannozzi, Andrea M. A1 - Haugen, Øyvind Pernell A1 - Kainourgios, Panagiotis A1 - von der Kammer, Frank A1 - Kirchner, Markus J. A1 - Lomax-Vogt, Madeleine A1 - Lujic, Tamara A1 - Milczewski, Frank A1 - Moussawi, Mhamad Aly A1 - Ortelli, Simona A1 - Parac-Vogt, Tatjana N. A1 - Potthoff, Annegret A1 - Reinosa, Julian J. A1 - Röschter, Sophie A1 - Sacco, Alessio A1 - Wimmer, Lukas A1 - Zanoni, Ilaria A1 - Dailey, Lea Ann T1 - Correction: Characterizing nanoplastic suspensions of increasing complexity: Inter-laboratory comparison of size measurements using dynamic light scattering N2 - Correction for ‘Characterizing nanoplastic suspensions of increasing complexity: Inter-laboratory comparison of size measurements using dynamic light scattering’ by Korinna Altmann et al., Environ. Sci.: Nano, 2025, 12, 5242–5256, https://doi.org/10.1039/D5EN00645G. PY - 2026 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-656330 DO - https://doi.org/10.1039/d6en90001a SN - 2051-8153 VL - 13 IS - 2 SP - 1233 PB - Royal Society of Chemistry (RSC) CY - Cambridge AN - OPUS4-65633 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Trimpin, Sarah A1 - Yenchick, Frank S. A1 - Lee, Chuping A1 - Hoang, Khoa A1 - Pophristic, Milan A1 - Karki, Santosh A1 - Marshall, Darrell D. A1 - Lu, I-Chung A1 - Lutomski, Corinne A. A1 - El-Baba, Tarick J. A1 - Wang, Beixi A1 - Pagnotti, Vincent S. A1 - Meher, Anil K. A1 - Chakrabarty, Shubhashis A1 - Imperial, Lorelei F. A1 - Madarshahian, Sara A1 - Richards, Alicia L. A1 - Lietz, Christopher B. A1 - Moreno-Pedraza, Abigail A1 - Leach, Samantha M. A1 - Gibson, Stephen C. A1 - Elia, Efstathios A. A1 - Thawoos, Shameemah M. A1 - Woodall, Daniel W. A1 - Jarois, Dean R. A1 - Davis, Eric T.J. A1 - Liao, Guochao A1 - Muthunayake, Nisansala S. A1 - Redding, McKenna J. A1 - Reynolds, Christian A. A1 - Anthony, Thilani M. A1 - Vithanarachchi, Sashiprabha M. A1 - DeMent, Paul A1 - Adewale, Adeleye O. A1 - Yan, Lu A1 - Wager-Miller, James A1 - Ahn, Young-Hoon A1 - Sanderson, Thomas H. A1 - Przyklenk, Karin A1 - Greenberg, Miriam L. A1 - Suits, Arthur G. A1 - Allen, Matthew J. A1 - Narayan, Srinivas B. A1 - Caruso, Joseph A. A1 - Stemmer, Paul M. A1 - Nguyen, Hien M. A1 - Weidner, Steffen A1 - Rackers, Kevin J. A1 - Djuric, Ana A1 - Shulaev, Vladimir A1 - Hendrickson, Tamara L. A1 - Chow, Christine S. A1 - Pflum, Mary Kay H. A1 - Grayson, Scott M. A1 - Lobodin, Vladislav V. A1 - Guo, Zhongwu A1 - Ni, Chi-Kung A1 - Walker, J. Michael A1 - Mackie, Ken A1 - Inutan, Ellen D. A1 - McEwen, Charles N. T1 - New Processes for Ionizing Nonvolatile Compounds in Mass Spectrometry: The Road of Discovery to Current State-of-the-Art N2 - This Perspective covers discovery and mechanistic aspects aswell as initial applications of novel ionization processes for use in massspectrometry that guided us in a series of subsequent discoveries, instrumentdevelopments, and commercialization. Vacuum matrix-assisted ionization onan intermediate pressure matrix-assisted laser desorption/ionization sourcewithout the use of a laser, high voltages, or any other added energy wassimply unbelievable, at first. Individually and as a whole, the variousdiscoveries and inventions started to paint, inter alia, an exciting new pictureand outlook in mass spectrometry from which key developments grew thatwere at the time unimaginable, and continue to surprise us in its simplisticpreeminence. We, and others, have demonstrated exceptional analyticalutility. Our current research is focused on how best to understand, improve, and use these novel ionization processes throughdedicated platforms and source developments. These ionization processes convert volatile and nonvolatile compounds from solid orliquid matrixes into gas-phase ions for analysis by mass spectrometry using, e.g., mass-selected fragmentation and ion mobilityspectrometry to provide accurate, and sometimes improved, mass and drift time resolution. The combination of research anddiscoveries demonstrated multiple advantages of the new ionization processes and established the basis of the successes that lead tothe Biemann Medal and this Perspective. How the new ionization processes relate to traditional ionization is also presented, as wellas how these technologies can be utilized in tandem through instrument modification and implementation to increase coverage ofcomplex materials through complementary strengths. KW - Mass spectrometry PY - 2024 DO - https://doi.org/10.1021/jasms.3c00122 SN - 1879-1123 VL - 35 IS - 12 SP - 2753 EP - 2784 PB - American Chemical Society (ACS) AN - OPUS4-61417 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Marchant, H. K. A1 - Tegetmeyer, H. E. A1 - Ahmerkamp, S. A1 - Holtappels, M. A1 - Lavik, G. A1 - Graf, J. A1 - Schreiber, Frank A1 - Mussmann, M. A1 - Strous, M. A1 - Kuypers, M. M. M. T1 - Metabolic specialization of denitrifiers in permeable sediments controls N2O emissions N2 - Coastal oceans receive large amounts of anthropogenic fixed nitrogen (N), most of which is denitrified in the sediment before reaching the open ocean. Sandy sediments, which are common in coastal regions, seem to play an important role in catalysing this N‐loss. Permeable sediments are characterized by advective porewater transport, which supplies high fluxes of organic matter into the sediment, but also leads to fluctuations in oxygen and nitrate concentrations. Little is known about how the denitrifying communities in these sediments are adapted to such fluctuations. Our combined results indicate that denitrification in eutrophied sandy sediments from the world's largest tidal flat system, the Wadden Sea, is carried out by different groups of microorganisms. This segregation leads to the formation of N2O which is advectively transported to the overlying waters and thereby emitted to the atmosphere. At the same time, the production of N2O within the sediment supports a subset of Flavobacteriia which appear to be specialized on N2O reduction. If the mechanisms shown here are active in other coastal zones, then denitrification in eutrophied sandy sediments may substantially contribute to current marine N2O emissions. KW - Nitrous oxide KW - Denitrification KW - Cross-feeding PY - 2018 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-463061 UR - https://onlinelibrary.wiley.com/doi/full/10.1111/1462-2920.14385 DO - https://doi.org/10.1111/1462-2920.14385 SN - 1462-2920 SN - 1462-2912 VL - 20 IS - 12 SP - 4486 EP - 4502 PB - John Wiley & Sons Ltd AN - OPUS4-46306 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Westwood, S. A1 - Josephs, R. A1 - Daireaux, A. A1 - Wielgosz, R. A1 - Davies, S. A1 - Kang, M. A1 - Ting, H. A1 - Philipp, Rosemarie A1 - Malz, Frank A1 - Shimizu, Y. A1 - Frias, E. A1 - Pérez, M. A1 - Apps, P. A1 - Fernandes-Whaley, M. A1 - De Vos, B. A1 - Wiagnon, K. A1 - Ruangrittinon, N. A1 - Wood, S. A1 - Duewer, D.L. A1 - Schantz, M.M. A1 - Bedner, M. A1 - Hancock, D. A1 - Esker, J. T1 - An international comparison of mass fraction purity assignment of theophylline: CCQM pilot study CCQM-P20.e (Theophylline) PY - 2009 DO - https://doi.org/10.1088/0026-1394/46/1A/08019 SN - 0026-1394 SN - 1681-7575 VL - 46 IS - 08019 SP - 1 EP - 37 PB - Inst. of Physics Publ. CY - Bristol AN - OPUS4-20030 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Sokolowski-Tinten, K. A1 - Barty, A. A1 - Boutet, S. A1 - Shymanovich, U. A1 - Chapman, H. A1 - Bogan, M. A1 - Marchesini, S. A1 - Hau-Riege, S. A1 - Stojanovic, N. A1 - Bonse, Jörn A1 - Rosandi, Y. A1 - Urbassek, H. M. A1 - Tobey, R. A1 - Ehrke, H. A1 - Cavalleri, A. A1 - Düsterer, S. A1 - Redlin, H. A1 - Frank, M. A1 - Bajt, S. A1 - Schulz, J. A1 - Seibert, M. A1 - Hajdu, J. A1 - Treusch, R. A1 - Bostedt, C. A1 - Hoener, M. A1 - Möller, T. T1 - Short-pulse laser induced transient structure formation and ablation studied with time-resolved coherent XUV-scattering T2 - International high-power laser ablation conference CY - Santa Fe, USA DA - 2010-04-18 KW - Femtosecond laser ablation KW - Free electron lasers KW - Coherent scattering PY - 2010 SN - 978-0-7354-0828-9 N1 - Serientitel: AIP conference proceedings – Series title: AIP conference proceedings IS - 1278 SP - 373 EP - 379 PB - American Institute of Physics CY - Melville, NY, USA AN - OPUS4-22230 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Pauw, Brian Richard A1 - Smales, Glen Jacob A1 - Anker, A. S. A1 - Annadurai, V. A1 - Balazs, D. M. A1 - Bienert, Ralf A1 - Bouwman, W. G. A1 - Breßler, Ingo A1 - Breternitz, J. A1 - Brok, E. S. A1 - Bryant, G. A1 - Clulow, A. J. A1 - Crater, E. R. A1 - De Geuser, F. A1 - Del Giudice, A. A1 - Deumer, J. A1 - Disch, S. A1 - Dutt, S. A1 - Frank, K. A1 - Fratini, E. A1 - Garcia, P. R. A. F. A1 - Gilbert, E. P. A1 - Hahn, Marc Benjamin A1 - Hallett, J. A1 - Hohenschutz, M. A1 - Hollamby, M. A1 - Huband, S. A1 - Ilavsky, J. A1 - Jochum, J. K. A1 - Juelsholt, M. A1 - Mansel, B. W. A1 - Penttilä, P. A1 - Pittkowski, R. K. A1 - Portale, G. A1 - Pozzo, L. D. A1 - Rochels, L. A1 - Rosalie, Julian A1 - Saloga, Patrick E. J. A1 - Seibt, S. A1 - Smith, A. J. A1 - Smith, G. N. A1 - Spiering, G. A. A1 - Stawski, Tomasz M. A1 - Taché, O. A1 - Thünemann, Andreas A1 - Toth, K. A1 - Whitten, A. E. A1 - Wuttke, J. T1 - The human factor - Results of a small-angle scattering data analysis round robin N2 - A round-robin study has been carried out to estimate the impact of the human element in small-angle scattering data analysis. Four corrected datasets were provided to participants ready for analysis. All datasets were measured on samples containing spherical scatterers, with two datasets in dilute dispersions and two from powders. Most of the 46 participants correctly identified the number of populations in the dilute dispersions, with half of the population mean entries within 1.5% and half of the population width entries within 40%. Due to the added complexity of the structure factor, far fewer people submitted answers on the powder datasets. For those that did, half of the entries for the means and widths were within 44 and 86%, respectively. This round-robin experiment highlights several causes for the discrepancies, for which solutions are proposed. KW - Round Robin KW - Data analysis KW - Small-angle scattering KW - Nanomaterials KW - Interlaboratory comparability KW - Nanostructure quantification KW - Methodology KW - MOUSE PY - 2023 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-587091 DO - https://doi.org/10.1107/S1600576723008324 SN - 1600-5767 VL - 56 IS - 6 SP - 1618 EP - 1629 PB - Wiley-Blackwell CY - Oxford AN - OPUS4-58709 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Schreiber, Frank A1 - Zimmermann, M. A1 - Escrig, S. A1 - Lavik, G. A1 - Kuypers, M.M.M. A1 - Meibom, A. A1 - Ackermann, M. T1 - Substrate and electron donor limitation induce phenotypic heterogeneity in different metabolic activities in a green sulphur bacterium N2 - Populations of genetically identical cells can display marked variation in phenotypic traits; such variation is termed phenotypic heterogeneity. Here, we investigate the effect of substrate and electron donor limitation on phenotypic heterogeneity in N2 and CO2 fixation in the green sulphur bacterium Chlorobium phaeobacteroides. We grew populations in chemostats and batch cultures and used stable isotope labelling combined with nanometer‐scale secondary ion mass spectrometry (NanoSIMS) to quantify phenotypic heterogeneity. Experiments in H2S (i.e. electron donor) limited chemostats show that varying levels of NH4+ limitation induce heterogeneity in N2 fixation. Comparison of phenotypic heterogeneity between chemostats and batch (unlimited for H2S) populations indicates that electron donor limitation drives heterogeneity in N2 and CO2 fixation. Our results demonstrate that phenotypic heterogeneity in a certain metabolic activity can be driven by different modes of limitation and that heterogeneity can emerge in different metabolic processes upon the same mode of limitation. In conclusion, our data suggest that limitation is a general driver of phenotypic heterogeneity in microbial populations. KW - NanoSIMS KW - Phenotypic heterogeneity PY - 2018 UR - https://onlinelibrary.wiley.com/doi/abs/10.1111/1758-2229.12616 DO - https://doi.org/10.1111/1758-2229.12616 SN - 1758-2229 VL - 10 IS - 2 SP - 179 EP - 183 PB - John Wiley & Sons Ltd AN - OPUS4-44596 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Beck, M. A1 - Becker, S. A1 - Beckmann, Jörg A1 - Cojocari, O. A1 - Feige, V. A1 - Fischer, B. A1 - Friederich, F. A1 - Globisch, B. A1 - Haupt, H. A1 - Hechtfischer, G. A1 - Hens, K. A1 - Hübers, H.-W. A1 - Jelonnek, J. A1 - Jonuscheit, J. A1 - Keil, A. A1 - Kleine-Ostmann, T. A1 - Nickel, H.-U. A1 - Peichl, M. A1 - Peters, O. A1 - Sprenger, T. A1 - Steiger, A. A1 - van Frank, S. A1 - Vieweg, N. A1 - Werner, M. A1 - Wilk, R. T1 - Terahertzsysteme - Anwendungsfelder und Systeme N2 - Die nicht ionisierende elektromagnetische Strahlung im Bereich von Terahertz-Frequenzen ermöglicht berührungslose und zerstörungsfreie Mess- und Prüftechnik in zahlreichen Bereichen. Nach ersten Anwendungen in der Astronomie und der Atmosphärenforschung wurden in letzter Zeit Anwendungsfelder in der Sicherheitstechnik, der Medizintechnik, der Nachrichtentechnik und der zerstörungsfreien Prozess- und Qualitätskontrolle erschlossen. Dielektrische Materialien wie Kunststoffe und Keramiken können von Terahertz-Wellen durchdrungen werden. Das ermöglicht Untersuchungen des Objektinneren ohne spezielle Schutzmaßnahmen, wie sie z.B. beim Röntgen notwendig sind. Die Richtlinie erleichtert die Verständigung zwischen Nutzern, Herstellern und dem Vertrieb von Terahertz-Systemen. In der Richtlinie werden bekannte Einsatzgebiete sowie die eingesetzten Verfahren und Funktionsprinzipien aufgeführt, um den Leser bei der Auswahlentscheidung zu unterstützen. Nach einer kurzen Einführung in die physikalischen Grundlagen und Hinweisen zur elektromagnetischen Verträglichkeit, zum Strahlenschutz und zur regulierten Frequenzvergabe werden die verschiedenen Geräteklassen von Terahertz-Systemen ausführlich vorgestellt. Die Richtlinie gibt Hinweise zur messtechnischen Charakterisierung von Terahertz-Wellen. Einsatzgebiete von Terahertz-Systemen, wie die zerstörungsfreie Prüfung, die Dicken- und Abstandsmessung, die Tomografie und die chemische Analytik, werden mit ihren spezifischen Eigenschaften im Detail beschrieben. Umfangreiche Literaturverweise vereinfachen eine vertiefte Beschäftigung mit den Themen der Richtlinie. Eine tabellarische Übersicht mit einer Zusammenfassung, welche Terahertz-Systeme für welche Anwendungsfelder eingesetzt werden können, vervollständigt die Richtlinie. KW - Terahertzsysteme KW - THz-Wellen PY - 2018 UR - https://www.vdi.de/5590 VL - VDI/VDE 5590 Blatt 2 SP - 1 EP - 27 PB - VDI-Verlag CY - Düsseldorf ET - Entwurf - November 2018 AN - OPUS4-46727 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Sokolowski-Tinten, K. A1 - Barty, A. A1 - Boutet, S. A1 - Shymanovich, U. A1 - Bogan, M. A1 - Marchesini, S. A1 - Hau-Riege, S. A1 - Stojanovic, N. A1 - Bonse, Jörn A1 - Tobey, R. A1 - Ehrke, H. A1 - Cavalleri, A. A1 - Duesterer, S. A1 - Frank, M. A1 - Bajt, S. A1 - Schulz, J. A1 - Seibert, M. A1 - Hajdu, J. A1 - Treusch, R. A1 - Chapman, H. T1 - Short-pulse laser induced transient structure formation and ablation studied with time-resolved coherent XUV-scattering N2 - XUV- and X-ray free-electron-lasers (FEL) combine short wavelength, ultrashort pulse duration, spatial coherence and high intensity. This unique combination of properties opens up new possibilities to study the dynamics of non-reversible phenomena with ultrafast temporal and nano- to atomic-scale spatial resolution. In this contribution we wish to present results of time-resolved experiments performed at the XUV-FEL FLASH (HASYLAB/Hamburg) aimed to investigate the nano-scale structural dynamics of laser-irradiated materials. Thin films and fabricated nano-structures, deposited on Si3N4-membranes, have been excited with ultrashort optical laser pulses. The dynamics of the non-reversible structural evolution of the irradiated samples during laser-induced melting and ablation has been studied in an optical pump - XUV-probe configuration by means of single-shot coherent scattering techniques (i.e. diffraction imaging [1]). In a first set of experiments we investigated the formation of laser induced periodic surface structures (LIPSS) on the surface of thin Si-films (thickness 100 nm). In a simplified view LIPPS are generated as a result of interference between the incident laser pulse and surface scattered waves which leads to a periodically modulated energy deposition. Time-resolved scattering using femtosecond XUV-pulses (with a wavelength of 13.5 nm and 7 nm) allowed us to directly follow LIPSS evolution on an ultrafast time-scale and with better than 40 nm spatial resolution. The observed scattering patterns show almost quantitative agreement with theoretical predictions [2] and reveal that the LIPSS start to form already during the 12 ps pump pulse. In the second set of measurements we studied picosecond and femtosecond laser induced ablation and disintegration of fabricated nano-structures. Correlations of coherent diffraction patterns measured at various time delays to the pattern of the undisturbed object show that order in the structure is progressively lost starting from short length scales. This structural rearrangement progresses at close to the speed of sound in the material. Under certain circumstances (e.g. adequate sampling) it became also possible to reconstruct real-space images of the object as it evolves over time [3]. The possibility of femtosecond single-shot imaging of ultrafast dynamic processes with nanoscale resolution provides yet more details of the physical processes involved. [1] H. N. Chapman et al. Nature Phys. 2, 839 (2006). [2] J. F. Young et al., Phys. Rev. B 27, 1155 (1983). [3] A. Barty et al. Nature Phot. 2, 415 (2008). T2 - Fall meeting of the materials research society 2009 CY - Boston, MA, USA DA - 2009-11-30 KW - Femtosecond laser ablation KW - Laser-induced periodic surface structures KW - Time-resolved coherent XUV scattering KW - Semiconductor KW - Silicon PY - 2010 DO - https://doi.org/10.1557/PROC-1230-MM05-03 N1 - Serientitel: Materials Research Society symposium proceedings – Series title: Materials Research Society symposium proceedings VL - 1230E IS - Paper 1230-MM05-03 SP - 1 EP - 6 AN - OPUS4-21438 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - RPRT A1 - Göbel, E. O. A1 - Hasche, K. A1 - Ulm, G. A1 - Krumrey, M. A1 - Ade, G. A1 - Stümpel, J. A1 - Herrmann, K. A1 - Koenders, L. A1 - Thomsen-Schmidt, P. A1 - Pohlenz, F. A1 - Xu, M. A1 - Dai, G. A1 - Hoffmann, K.-P. A1 - Busch, I. A1 - Frank, W. A1 - Procop, M. A1 - Beck, Uwe T1 - Kalibrierte Schichtdicken-Maßverkörperungen für Nanometerschichten, Teilvorhaben - Kalibrierung von Schichtdicken-Maßverkörperungen im Nanometerbereich - Abschlussbericht des BMBF Verbundvorhabens 13N7704 - 13N77041 KW - Schichtdicke KW - Nanometerbereich PY - 2003 UR - http://edok01.tib.uni-hannover.de/edoks/e01fb02/373214030.pdf SP - 1 EP - 131 PB - Physikalisch-Technische Bundesanstalt CY - Dresden AN - OPUS4-25428 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - INPR A1 - Pauw, Brian Richard A1 - Smales, Glen Jacob A1 - Anker, A. S. A1 - Balazs, D. M. A1 - Beyer, F. L. A1 - Bienert, Ralf A1 - Bouwman, W. G. A1 - Breßler, Ingo A1 - Breternitz, J. A1 - Brok, E. S. A1 - Bryant, G. A1 - Clulow, A. J. A1 - Crater, E. R. A1 - De Geuser, F. A1 - Giudice, A. D. A1 - Deumer, J. A1 - Disch, S. A1 - Dutt, S. A1 - Frank, K. A1 - Fratini, E. A1 - Gilbert, E. P. A1 - Hahn, Marc Benjamin A1 - Hallett, J. A1 - Hohenschutz, Max A1 - Hollamby, M. J. A1 - Huband, S. A1 - Ilavsky, J. A1 - Jochum, J. K. A1 - Juelsholt, M. A1 - Mansel, B. W. A1 - Penttilä, P. A1 - Pittkowski, R. K. A1 - Portale, G. A1 - Pozzo, L. D. A1 - Ricardo de Abreu Furtado Garcia, P. A1 - Rochels, L. A1 - Rosalie, Julian A1 - Saloga, P. E. J. A1 - Seibt, S. A1 - Smith, A. J. A1 - Smith, G. N. A1 - Annadurai, V. A1 - Spiering, G. A. A1 - Stawski, Tomasz A1 - Taché, O. A1 - Thünemann, Andreas A1 - Toth, K. A1 - Whitten, A. E. A1 - Wuttke, J. T1 - The human factor - Results of a small-angle scattering data analysis round robin N2 - A Round Robin study has been carried out to estimate the impact of the human element in small-angle scattering data analysis. Four corrected datasets were provided to participants ready for analysis. All datasets were measured on samples containing spherical scatterers, with two datasets in dilute dispersions, and two from powders. Most of the 46 participants correctly identified the number of populations in the dilute dispersions, with half of the population mean entries within 1.5 % and half of the population width entries within 40 %, respectively. Due to the added complexity of the structure factor, much fewer people submitted answers on the powder datasets. For those that did, half of the entries for the means and widths were within 44 % and 86 % respectively. This Round Robin experiment highlights several causes for the discrepancies, for which solutions are proposed. KW - Round robin KW - Sall-angle scattering KW - Nanostructure quantification KW - Nanostructure KW - SAXS KW - MOUSE KW - X-ray scattering KW - Size distribution KW - Nanoparticles PY - 2023 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-571342 DO - https://doi.org/10.48550/arXiv.2303.03772 SP - 1 EP - 23 PB - Cornell University CY - Ithaca, NY AN - OPUS4-57134 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Becker, S. A1 - Beckmann, Jörg A1 - Braun, M.-T. A1 - Cojocari, O. A1 - Feige, V. A1 - Fischer, B. A1 - Friederich, F. A1 - Globisch, B. A1 - Hechtfischer, G. A1 - Hens, K. A1 - Hübers, H.-W. A1 - Jelonnek, J. A1 - Jonuscheit, J. A1 - Keil, A. A1 - Kleine-Ostmann, T. A1 - Marquardt, E. A1 - Mayr, M. A1 - Nickel, H.-U. A1 - Nüßler, D. A1 - Peichl, M. A1 - Peters, O. A1 - Schür, J. A1 - Sprenger, T. A1 - Steiger, A. A1 - van Frank, S. A1 - Vieweg, N. A1 - Wilk, R. ED - Jonuscheit, J. ED - Marquardt, E. T1 - Terahertzsysteme und Anwendungsfelder N2 - Der Frequenzbereich der Terahertzwellen liegt im elektromagnetischen Spektrum zwischen den Mikrowellen und dem infraroten Licht – also etwa im Bereich von 0,1 bis 10 Terahertz (THz). Der VDI-Statusreport „Terahertzsysteme und Anwendungen“ stellt die unterschiedlichen Konzepte für Terahertzsysteme vor und zeigt Anwendungsbeispiele, bei denen die Terahertztechnik erfolgreich eingesetzt wird. Umfangreiche Literaturangaben ermöglichen eine intensivere Beschäftigung mit allen Themen des VDI-Statusreports. KW - Terahertzsysteme PY - 2020 UR - https://www.vdi.de/ueber-uns/presse/publikationen/details/terahertzsysteme-und-anwendungsfelder SP - 1 EP - 44 PB - Verein Deutscher Ingenieure (VDI) CY - Düsseldorf AN - OPUS4-50556 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Becker, S. A1 - Beckmann, Jörg A1 - Cojocari, O. A1 - Feige, V. A1 - Fischer, B. A1 - Friederich, F. A1 - Globisch, B. A1 - Hechtfischer, G. A1 - Hens, K. A1 - Hübers, H.-W. A1 - Jelonnek, J. A1 - Jonuscheit, J. A1 - Keil, A. A1 - Kleine-Ostmann, T. A1 - Mayr, M. A1 - Nüßler, D. A1 - Peichl, M. A1 - Peters, O. A1 - Schür, J. A1 - Sprenger, T. A1 - Steiger, A. A1 - van Frank, S. A1 - Vieweg, N. A1 - Wilk, R. T1 - Terahertzsysteme - Zeitbereichsspektrometer (TDS-Systeme) N2 - Diese Richtlinie definiert Kenngrößen und Messverfahren, um Terahertzsysteme für die Zeitbereichsspektroskopie (TDS)zu spezifizieren. So können Hersteller ihre Systeme übereinstimmend beschreiben und Anwender einfach Systeme vergleichen. Systeme für die Terahertz-Zeitbereichsspektroskopie sind aktive Systeme und nutzen verschiedene Techniken sowohl zur Erzeugung als auch zur zeitaufgelösten Messung von breitbandigen Terahertzimpulsen. Die dazugehörigen Terahertzspektren und -Phasen werden nach einer zeitlichen Abtastung über eine Fourier-Transformation berechnet. In dieser Richtlinie wird ein Überblick über die Funktionsweisen von Zeitbereichsspektrometern gegeben, die eingesetzten Messverfahren näher erläutert sowie die benötigten Begriffe und Kenngrößen definiert. Die Richtlinie konzentriert sich dabei auf Systeme, die auf sogenannten Abtastmessverfahren (Sampling-Messverfahren) basieren. KW - TDS-Systeme PY - 2020 UR - https://www.vdi.de/5590 VL - VDI/VDE 5590 Blatt 2 SP - 1 EP - 22 PB - VDI-Verlag CY - Düsseldorf ET - Entwurf - Oktober 2020 AN - OPUS4-51947 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Hieu, D.T. A1 - Kosslick, H. A1 - Riaz, M. A1 - Schulz, A. A1 - Springer, A. A1 - Frank, M. A1 - Jäger, Christian A1 - Minh Thu, N.T. A1 - Son, L.T. T1 - Acidity and Stability of Bronsted Acid Sites in Green Clinoptilolite Catalysts and Catalytic Performance in the Etherification of Glycerol N2 - Natural zeolite clinoptilolite CLIN with a framework ratio of Si/Al ≥ 4 containing mainly potassium and calcium ions in its internal channel system was used as a starting material. The acidic HCLIN catalysts were prepared under soft conditions avoiding the use of environmental less benign mineral acids. The starting material was ion exchanged using a 0.2 M aqueous ammonium nitrate solution at a temperature 80 ◦C for 2 h. The obtained NH4CLIN was converted into the acid HCLIN catalyst by calcination at 300–600 ◦C. The obtained samples were characterized by XRD, FTIR, SEM/TEM, AAS, and EDX element mapping. The state of aluminium and silicon was studied by 27Al- and 29SiMAS NMR spectroscopy. The textural properties of the catalysts were investigated by nitrogen adsorption and desorption measurements. The Brønsted acidity of the HCLIN catalysts was studied by temperature-programmed decomposition of the exchanged ammonium ions releasing ammonia as well as 1H MAS NMR, {1H–27Al} Trapdor, and {1H–27Al} Redor experiments. The strongly agglomerated samples were crystalline and thermally stable up to >500 ◦C. Although a part of the clinoptilolite framework is maintained up to 600 ◦C, a loss of crystallinity is already observed starting from 450 ◦C. The specific surface areas of the starting CLIN and ammonium exchanged NH4CLIN are low with ca. 26 m2/g. The pores are nearly blocked by the exchangeable cations located in the zeolite pores. The thermal decomposition of the ammonium ions by calcination at 400 ◦C causes an opening of the pore entrances and a markable increase in the specific micropore area and micropore volume to ca. 163 m2/g and 0.07 cm3/g, respectively. It decreases with further rising calcination temperature indicating some structural loss. The catalysts show a broad distribution of Brønsted acid sites (BS) ranging from weak to strong sites as indicated the thermal decomposition of exchanged ammonium ions (TPDA). The ammonium ion decomposition leaving BS, i.e., H+ located at Al–O–Si framework bridges, starts at ≥250 ◦C. A part of the Brønsted sites is lost after calcination specifically at 500 ◦C. It is related to the formation of penta-coordinated aluminium at the expense of tetrahedral framework aluminium. The Brønsted sites are partially recreated after repeated ammonium ion exchange. The catalytic performance of the acidic HCLIN catalysts was tested in the etherification of glycerol as a green renewable resource with different C1 -C4 alcohols. The catalysts are highly active in the etherification of glycerol, especially with alcohols containing the branched, tertiary alkyl groups. Highest activity is observed with the soft activated catalyst HCLIN300 (300 ◦C, temperature holding time: 1 min). A total of 78% conversion of glycerol to mono and di ether were achieved with tert-butanol at 140 ◦C after 4 h of reaction. The mono- and di-ether selectivity were 75% and 25%, respectively. The catalyst can be reused. KW - Etherification KW - Glycerol KW - Zeolite KW - Clinoptilolite KW - Bronsted acidity KW - Dehydroxylation PY - 2022 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-546982 DO - https://doi.org/10.3390/catal12030253 VL - 12 IS - 3 SP - 1 EP - 24 PB - MDPI AN - OPUS4-54698 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - RPRT A1 - Thieme-Hack, M. A1 - Berghaus, U. A1 - Brümmer, F. A1 - Elsner, U. A1 - Färber, C. A1 - Frank, D. A1 - Illgas, M. A1 - Kalbe, Ute A1 - Kathage, J. A1 - Leers, A. A1 - Müller, B. A1 - Röger-Göpfert, C. A1 - Russland, H.-J. A1 - Schnabel, B. A1 - Schneider, O. A1 - Schockmann, D. A1 - Schomakers, H. A1 - Schwalbe, D. A1 - Stegemann, D. A1 - van den Berg, T. A1 - Kramps, S. T1 - Fachbericht Kunststoffsportböden - Nachhaltige Kunststoffbelagsauswahl für Sportfreianlagen N2 - Kunststoff- und Kunststoffrasenflächen kommt bei intensiv genutzten Flächen als Allwetterbeläge eine große Bedeutung zu. Sie leisten einen wichtigen Beitrag zur Absicherung eines ganzjähriger Sportangebote. Gerade Kunststoffrasen ist aber in den letzten Jahren häufig in die Kritik geraten, insbesondere durch gefährliche Inhaltsstoffe und andere negative Einflüsse auf die Umwelt. Dies hat bei Bauherren zu einer Verunsicherung geführt und Fragen aufgeworfen, die erst teilweise beantwortet sind. Die Diskussionen rund um diesen Allwetterbelag haben bereits dazu geführt, dass von Seiten der Industrie viel verändert wurde und neue innovative Lösungen gefunden werden. Der Fachbericht stellt eine Handreichung für Fachleute und interessierte Laien dar, um mehr Klarheit besonders hinsichtlich der Umweltanforderungen zu erzielen. KW - Kunststoffsportbeläge KW - Kunstrasen KW - Umweltverträglichkeit KW - Schadstofftransfer KW - Mikroplastik PY - 2022 UR - https://shop.fll.de/de/fachbericht-kunststoffsportboeden-broschuere.html SP - 1 EP - 70 PB - Forschungsgesellschaft Landschaftsentwicklung Landschaftsbau (FLL) CY - Bonn AN - OPUS4-54390 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Chan, George C.-Y. A1 - Hieftje, Gary M. A1 - Omenetto, Nicoló A1 - Axner, Ove A1 - Bengtson, Arne A1 - Bings, Nicolas H. A1 - Blades, Michael W. A1 - Bogaerts, Annemie A1 - Bolshov, Mikhail A. A1 - Broekaert, José A.C. A1 - Chan, WingTat A1 - Costa-Fernández, José M. A1 - Crouch, Stanley R. A1 - De Giacomo, Alessandro A1 - D’Ulivo, Alessandro A1 - Engelhard, Carsten A1 - Falk, Heinz A1 - Farnsworth, Paul B. A1 - Florek, Stefan A1 - Gamez, Gerardo A1 - Gornushkin, Igor B. A1 - Günther, Detlef A1 - Hahn, David W. A1 - Hang, Wei A1 - Hoffmann, Volker A1 - Jakubowski, Norbert A1 - Karanassios, Vassili A1 - Koppenaal, David W. A1 - Kenneth Marcus, R. A1 - Noll, Reinhard A1 - Olesik, John W. A1 - Palleschi, Vincenzo A1 - Panne, Ulrich A1 - Pisonero, Jorge A1 - Ray, Steven J. A1 - Resano, Martín A1 - Russo, Richard E. A1 - Scheeline, Alexander A1 - Smith, Benjamin W. A1 - Sturgeon, Ralph E. A1 - Todolí, José-Luis A1 - Tognoni, Elisabetta A1 - Vanhaecke, Frank A1 - Webb, Michael R. A1 - Winefordner, James D. A1 - Yang, Lu A1 - Yu, Jin A1 - Zhang, Zhanxia T1 - Landmark Publications in Analytical Atomic Spectrometry: Fundamentals and Instrumentation Development N2 - The almost-two-centuries history of spectrochemical analysis has generated a body of literature so vast that it has become nearly intractable for experts, much less for those wishing to enter the field. Authoritative, focused reviews help to address this problem but become so granular that the overall directions of the field are lost. This broader perspective can be provided partially by general overviews but then the thinking, experimental details, theoretical underpinnings and instrumental innovations of the original work must be sacrificed. In the present compilation, this dilemma is overcome by assembling the most impactful publications in the area of analytical atomic spectrometry. Each entry was proposed by at least one current expert in the field and supported by a narrative that justifies its inclusion. The entries were then assembled into a coherent sequence and returned to contributors for a round-robin review. KW - Analytical atomic spectrometry KW - Spectroscopy KW - Instrumental analysis PY - 2024 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-621588 DO - https://doi.org/10.1177/00037028241263567 SN - 1943-3530 VL - 78 SP - 1 EP - 456 PB - Sage CY - London AN - OPUS4-62158 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ocker, L. A1 - Lisec, Jan A1 - Seitz, G. A1 - Adamus, A. A1 - Hempfling, L. A1 - Wagner, B. A1 - Vahdad, R. A1 - Verburg, F. A. A1 - Luster, M. A1 - Schurrat, T. A1 - Bier, D. A1 - Frank, M. A1 - Engel, N. T1 - Hypericin and its radio iodinated derivatives – A novel combined approach for the treatment of pediatric alveolar rhabdomyosarcoma cells in vitro N2 - In this in vitro study, we got a first insight of a possible potential of Hypericin for the treatment of pediatric soft tissue sarcoma. By coupling with radioiodine, we developed a novel approach for a combined anti-tumor treatment. The in vitro experiments lay the foundation for further in vivo experiments, which are needed to study the effects of a sequential administration of 131I-HYP and HYP. KW - Mass-Spectrometry KW - Cancer PY - 2020 VL - 29 SP - 101588 PB - Elsevier B.V. AN - OPUS4-49601 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Nikolic, Nela A1 - Dal Co, Alma A1 - Kiviet, Daniel J. A1 - Bergmiller, Tobias A1 - Littmann, Sten A1 - Kuypers, Marcel M. M. A1 - Ackermann, Martin A1 - Schreiber, Frank T1 - Cell-to-cell variation and specialization in sugar metabolism in clonal bacterial populations N2 - While we have good understanding of bacterial metabolism at the population level, we know little about the metabolic behavior of individual cells: do single cells in clonal populations sometimes specialize on different metabolic pathways? Such metabolic specialization could be driven by stochastic gene expression and could provide individual cells with growth benefits of specialization. We measured the degree of phenotypic specialization in two parallel metabolic pathways, the assimilation of glucose and arabinose. We grew Escherichia coli in chemostats, and used isotope-labeled sugars in combination with nanometer-scale secondary ion mass spectrometry and mathematical modeling to quantify sugar assimilation at the single-cell level. We found large variation in metabolic activities between single cells, both in absolute assimilation and in the degree to which individual cells specialize in the assimilation of different sugars. Analysis of transcriptional reporters indicated that this variation was at least partially based on cell-to-cell variation in gene expression. Metabolic differences between cells in clonal populations could potentially reduce metabolic incompatibilities between different pathways, and increase the rate at which parallel reactions can be performed. KW - Metabolism KW - Escherichia coli KW - Phenotypic diversity KW - Phenotypic heterogeneity PY - 2017 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-438873 UR - http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007122 DO - https://doi.org/10.1371/journal.pgen.1007122 SN - 1553-7404 VL - 13 IS - 12 SP - e1007122, 1 EP - e1007122, 24 PB - Public Library of Science CY - Cambridge, United Kingdom AN - OPUS4-43887 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Razzaq, M. Y. A1 - Behl, M. A1 - Frank, U. A1 - Koetz, J. A1 - Szczerba, Wojciech A1 - Lendlein, A. T1 - Oligo(omega-pentadecalactone) decorated magnetic nanoparticles N2 - Hybrid magnetic nanoparticles (mgNP) with a magnetite core diameter of 10 ± 1 nm surface functionalized with oligo(ω-pentadecalactone) (OPDL) oligomers with Mn between 1300 and 3300 g mol-1 could be successfully prepared having OPDL grafted from 200 mg g-1 to 2170 mg g-1. The particles are dispersible in chloroform resulting in stable suspensions. Magnetic response against an external magnetic field proved the superparamagnetic nature of the particles with a low coercivity (Bc) value of 297 µT. The combination of the advantageous superparamagnetism of the mgNP with the exceptional stability of OPDL makes these novel hybrid mgNP promising candidates as multifunctional building blocks for magnetic nanocomposites with tunable physical properties. KW - PPDL KW - OPDL KW - Magnetic core-shell nanoparticles PY - 2012 DO - https://doi.org/10.1039/c2jm16146j SN - 0959-9428 SN - 1364-5501 VL - 22 IS - 18 SP - 9237 EP - 9243 PB - Royal Society of Chemistry CY - Cambridge AN - OPUS4-25741 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Apel, Andreas A1 - Wille, Frank A1 - Moutarde, M. A1 - Sert, G. A1 - Caillard-Lizot, M.-T. A1 - Eckert, B. A1 - Konnai, A. A1 - Pstrak, D. A1 - Harvey, J. A1 - Desnoyers, B. A1 - Purcell, P. A1 - Fiaccabrino, V. T1 - Stowage during transport: a proposal for harmonization N2 - For stowage and retention during transport, the International Atomic EnergyAgency (IAEA) Transport regulations (SSR-6) only require that the package shall be securely stowed. Additional information is given in the IAEA guidance material (SSG-26), that includes specific load factors that should be considered in the safety demonstrations. Nevertheless, applicants commonly use other load factors to justify the design of the packaging attachment points. In particular, acceleration values vary between different countries and this may lead to difficulties during the validation of foreign approval certificates. Discussions with applicants identified that the load factors presented in the IAEA guidance material are not necessarily relevant for the different transport modes. For some modes, the load factors are representative of situations occurring in routine conditions of transport. For other modes, the load factors are more representative of situations occurring in normal or accident conditions of transport. Furthermore, the origins of the specified values are not clear. In this context, some IAEA TRANSSC members decided to review the stowage guidance. An international working group was constituted in 2013, including representatives of competent authorities, technical support organizations, and transport stakeholders. Several topics were discussed and many questions were raised during the two year review. For example, some discussions focused on Paper No.1031 2 the conditions which have to be considered for stowage design, both as relevant to the load factors used for strength and fatigue analysis, as well as the criteria which have to be considered for the package attachment points. In addition, related questions on operational aspects were also discussed. Overall, the working group concluded that new guidance material was warranted as input into SSG-26. As a result of those discussions, the international working group produced new guidance material for stowage in transport, addressing each of these topics. The proposal to modify the IAEA guidance material (SSG-26, Appendix IV), presented by France to the TRANSSC in the 2015 initiated Review cycle of the Regulations, was unanimously accepted and will be implemented in the next edition of the guidance material. T2 - PATRAM 2016 CY - Kobe, Japan DA - 18.09.2016 KW - Packages for radioactive material KW - IAEA regulations (SSR-6, SSG-26) KW - Tie-down and stowage KW - Load cases for transport KW - Design of the packaging attachment points PY - 2016 SP - Paper 1031, 1 EP - 8 AN - OPUS4-38644 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Munter, L.M. A1 - Sieg, H. A1 - Bethge, T. A1 - Liebsch, F. A1 - Bierkandt, Frank A1 - Schleeger, M. A1 - Bittner, H.J. A1 - Heberle, J. A1 - Jakubowski, Norbert A1 - Hildebrand, P.W. A1 - Multhaup, G. T1 - Model peptides uncover the role of the beta-secretase transmembrane sequence in metal ion mediated oligomerization N2 - The β-secretase or β-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the enzyme responsible for the formation of amyloid-β peptides, which have a major role in Alzheimer pathogenesis. BACE1 has a transmembrane sequence (TMS), which makes it unique among related proteases. We noticed that the BACE1 TMS contains an uncommon sulfur-rich motif. The sequence MxxxCxxxMxxxCxMxC spans the entire TMS, resembles metal ion binding motifs, and is highly conserved among homologues. We used a synthetic 31-mer model peptide comprising the TMS to study metal ion binding and oligomerization. Applying diverse biochemical and biophysical techniques, we detected dimer and trimer formation of the TMS peptide with copper ions. Replacement of the central Cys466 by Ala essentially abolished these effects. We show that the peptide undergoes a redox reaction with copper ions resulting in a disulfide bridge involving Cys466. Further, we find peptide trimerization that depends on the presence of monovalent copper ions and the sulfhydryl group of Cys466. We identified Cys466 as a key residue for metal ion chelation and to be the core of an oligomerization motif of the BACE1-TMS peptide. Our results demonstrate a novel metal ion controlled oligomerization of the BACE1 TMS, which could have an enormous therapeutic importance against Alzheimer disease. KW - Enzymes KW - Amyloid formation KW - Alzheimer disease KW - Copper PY - 2013 DO - https://doi.org/10.1021/ja410812r SN - 0002-7863 SN - 1520-5126 VL - 135 IS - 51 SP - 19354 EP - 19361 PB - American Chemical Society CY - Washington, DC AN - OPUS4-30543 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Julsing, M.K. A1 - Fichera, Mario Augusto A1 - Malz, Frank A1 - Ebbelaar, M. A1 - Bos, R. A1 - Woerdenbag, H. J. A1 - Quax, W.J. A1 - Kayser, O. T1 - Bioconversion of Mono- and Sesquiterpenoids by recombinant human Cytochrome P450 Monooxygenases N2 - Cytochrome P450 monooxygenases play an important role in the biosynthesis and metabolism of terpenoids. We explored the potential of recombinant human liver cytochrome P450 monooxygenases CYP1A2, CYP2C9, and CYP3A4, heterologously expressed in Escherichia coli, to convert mono- and sesquiterpenoids to human metabolites. This natural product group is a diverse class of secondary metabolites and includes several industrially and pharmaceutically interesting compounds. Incubation of cedrol with CYP3A4 resulted in a bioconversion of 74% (±8.9%) after 1 h of the unknown metabolites 2-hydroxycedrol and 4-hydroxycedrol, which have been structurally elucidated by 1H and 13C NMR and GC-MS. We conclude that recombinant human cytochrome P450 enzymes can be useful tools in a combinatorial biosynthesis strategy for the production of new natural products and for in vitro metabolization studies. KW - Cedrol KW - Cytochrome P450 KW - Drug metabolism KW - NMR KW - Terpenoids PY - 2008 DO - https://doi.org/10.1080/13880200802215487 SN - 1388-0209 SN - 1744-5116 VL - 46 IS - 10-11 SP - 710 EP - 718 PB - Informa Healthcare CY - New York, NY, USA AN - OPUS4-18912 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CHAP A1 - Sokolowski-Tinten, K. A1 - Bonse, Jörn A1 - Barty, A. A1 - Chapman, H.N. A1 - Bajt, S. A1 - Bogan, M.J. A1 - Boutet, S. A1 - Cavalleri, A. A1 - Düsterer, S. A1 - Frank, M. A1 - Hajdu, J. A1 - Hau-Riege, S. A1 - Marchesini, S. A1 - Stojanonovic, N. A1 - Treusch, R. ED - Stoian, R. ED - Bonse, Jörn T1 - In-Situ Observation of the Formation of Laser-Induced Periodic Surface Structures with Extreme Spatial and Temporal Resolution N2 - Irradiation of solid surfaces with intense ultrashort laser pulses represents a unique way of depositing energy into materials. It allows to realize states of extreme electronic excitation and/or very high temperature and pressure and to drive materials close to and beyond fundamental stability limits. As a consequence, structural changes and phase transitions often occur along unusual pathways and under strongly nonequilibrium conditions. Due to the inherent multiscale nature—both temporally and spatially—of these irreversible processes, their direct experimental observation requires techniques that combine high temporal resolution with the appropriate spatial resolution and the capability to obtain good quality data on a single pulse/event basis. In this respect, fourth-generation light sources, namely, short wavelength and short pulse free electron lasers (FELs), are offering new and fascinating possibilities. As an example, this chapter will discuss the results of scattering experiments carried out at the FLASH free electron laser at DESY (Hamburg, Germany), which allowed us to resolve laser-induced structure formation at surfaces on the nanometer to submicron length scale and in temporal regimes ranging from picoseconds to several nanoseconds with sub-picosecond resolution. KW - Laser-induced periodic surface structures, LIPSS KW - Capillary waves KW - Time-resolved scattering KW - Pump-probe experiments KW - Free electron laser PY - 2023 SN - 978-3-031-14751-7 SN - 978-3-031-14752-4 DO - https://doi.org/10.1007/978-3-031-14752-4_6 VL - 239 SP - 257 EP - 276 PB - Springer Nature Switzerland AG CY - Cham, Switzerland AN - OPUS4-57297 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Jahnke, Annika A1 - Beck, Aaron J. A1 - Becker, Richard L. A1 - Bedulina, Daria A1 - Braun, Ulrike A1 - Gerdts, Gunnar A1 - Hildebrandt, Lars A1 - Joerss, Hanna A1 - Klein, Ole A1 - Korduan, Janine A1 - Laforsch, Christian A1 - Lannig, Gisela A1 - Leslie, Heather A. A1 - Lips, Stefan A1 - Menger, Frank A1 - Nabi, Deedar A1 - Oberbeckmann, Sonja A1 - Primpke, Sebastian A1 - Pröfrock, Daniel A1 - Ramsperger, Anja F.R.M. A1 - Römerscheid, Mara A1 - Schmitt-Jansen, Mechthild A1 - Scholz-Böttcher, Barbara M. A1 - Tröppner, Oliver A1 - Wendt-Potthoff, Katrin A1 - Kühnel, Dana T1 - Perspective article: Multisectoral considerations to enable a circular economy for plastics N2 - Plastics are widely used but improper disposal and release lead to increasing global pollution, threatening environmental and human health. To address this issue, we suggest intersectoral collaboration to achieve zero plastic pollution. The outcomes of the project P-LEACH demonstrated the enormous complexity and range of potential toxic effects of plastic-associated chemicals and micro-/nanoplastics released into water from UV-weathered plastics. We initiated an intersectoral dialogue amongst scientists, manufacturers, regulators and representatives of civil society about how to alleviate the negative impacts of plastic pollution. Circular economy offers a framework for selecting non-toxic chemicals, extending product (re)use, and waste reduction, which act to alleviate pollution when applied to plastics. We suggest three measures to advance a circular economy of plastics: 1.) Increase simplicity of chemicals in virgin plastics combined with transparent information on the contents; 2.) Consider recyclability already in plastic material and product design; 3.) Foster communication through intersectoral dialogue. Major cornerstones are the provision of standardized, easy-to-use tools to characterize plastics and plastic leachates chemically and (eco)toxicologically, the enhancement of citizen awareness enabling them to make informed choices, the creation of economic incentives for manufacturers, and sector-specific regulations to provide products that safeguard environmental and human health. KW - Plastics KW - Circular economy KW - Cross-sectoral dialogue KW - Recyclability KW - Plastic-associated chemicals PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-638280 DO - https://doi.org/10.1016/j.jhazmat.2025.139326 SN - 0304-3894 VL - 496 SP - 1 EP - 9 PB - Elsevier B.V. AN - OPUS4-63828 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - RPRT A1 - Wiesler, F. A1 - Hund-Rinke, K. A1 - George, E. A1 - Greef, J.-M. A1 - Holz, F. A1 - Hölze, L.E. A1 - Hülsbergen, K.-J. A1 - Martin, S. A1 - Severin, K. A1 - Spielvogel, S. A1 - Geiger, P. A1 - Nawotke, C. A1 - Kehlenbeck, H. A1 - Schenkel, H. A1 - Adam, Christian A1 - Bloem, E. A1 - Frank, D. A1 - Goldbach, H.E. A1 - Heene, M. A1 - Kratz, S. A1 - Kruse, A. A1 - Möller, K. A1 - Pinnekamp, J. A1 - Schoumans, O.F. A1 - Vogel, Christian A1 - Wulf, S. T1 - Recyclingphosphate in der Düngung – Nutzen und Grenzen N2 - Weltweit werden etwa 80–85 % aller abgebauten Rohphosphate für die Produktion von Düngemitteln verwendet. Bei noch steigendem Bedarf an Phosphor (P) geht man derzeit davon aus, dass die weltweiten P-Reserven noch über 200 Jahre ausreichen. Um den P-Vorrat langfristig abzusichern, sollte der in Reststoffen enthaltene Phosphor möglichst umfänglich genutzt werden. Dieser Forderung trägt das von der Bundesregierung 2012 erstmals beschlossene Deutsche Ressourceneffizienzprogramm ProgRess Rechnung. Rohphosphat wird auch seitens der Europäischen Kommission aufgrundseiner ökonomischen Bedeutung und des unsicheren Angebots als „kritischer Rohstoff“ eingestuft. Vor diesem Hintergrund hat die Bundesregierung in der Verordnung zur Neuordnung der Klärschlammverwertung vom 27. September 2017 in Deutschland eine verpflichtende technische Rückgewinnung von Phosphor für Abwasserbehandlungsanlagen ab einer Ausbaugröße von 100.000 Einwohnerwerten (12 Jahre nach Inkrafttreten der Verordnung) bzw. ab einer Ausbaugröße von über 50.000 Einwohnerwerten (15 Jahre nach Inkrafttreten der Verordnung) vorgeschrieben. Die Verordnung enthält keine Vorgaben hinsichtlich der anzuwendenden Technologie bei der Phosphorrückgewinnung. Ausgenommen von der Rückgewinnungspflicht sind Klärschlämme mit niedrigen Phosphorgehalten (weniger als 20 Gramm Phosphor je Kilogramm Klärschlamm-Trockenmasse). Auch die im Jahre 2017 verabschiedeten neuen Rechtsvorschriften für die Düngung verlangen zukünftig einen nachhaltigen und ressourceneffizienten Umgang mit Nährstoffen bei der landwirtschaftlichen Erzeugung und schränken die P-Zufuhr insbesondere auf hoch versorgten Böden ein (Düngeverordnung vom 26. Mai 2017). Dies wird zu einem mehr am Pflanzenbedarf orientierten und ggf. vermehrt überbetrieblichen Einsatz von wirtschaftseigenen Düngern führen. Um den politischen und gesetzlichen Anforderungen gerecht zu werden, müssen einerseits wirksame und kosteneffiziente technische Verfahren zum P-Recycling (weiter)entwickelt werden. Andererseits müssen die Recyclingprodukte die Anforderungen für eine direkte Verwendung in der Landwirtschaft oder als Rohstoff für die Herstellung von Düngemitteln erfüllen. In dem vorliegenden Standpunkt wird zunächst der potenzielle Beitrag von Reststoffen zur Deckung des P-Bedarfs in der deutschen Pflanzenproduktion geschätzt. Für die wichtigsten Reststoffe werden technische Verfahren zur P-Rückgewinnung bzw. Aufarbeitung skizziert. Auf Basis der Anforderungen der Landwirtschaft bzw. der Düngemittelindustrie an die P-Recyclingprodukte werden deren Herstellungsverfahren bewertet. Schließlich wird der Regelungs- und Forschungsbedarf formuliert. KW - Phosphor KW - Düngemittel KW - Diffusive Gradients in thin films (DGT) PY - 2020 SP - 1 EP - 19 PB - Bundesministerium für Ernährung und Landwirtschaft (BMEL) CY - Berlin AN - OPUS4-51011 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wille, Frank A1 - Wolff, Dietmar A1 - Droste, Bernhard A1 - Völzke, Holger A1 - Baden, M. T1 - German approach and experience feedback of transport ability of SNF packages after interim storage N2 - In Germany the concept of dry interim storage of spent fuel in dual purpose metal casks is implemented, currently for periods of up to 40 years. The casks being used have an approved package design in accordance with the international transport regulations. The license for dry storage is granted on the German Atomic Energy Act with respect to the recently revised “Guidelines for dry interim storage of irradiated fuel assemblies and heat-generating radioactive waste in casks” by the German Waste management Commission (ESK). For transport on public routes between or after long term interim storage periods, it has to be ensured that the transport and storage casks fulfil the specifications of the transport approval or other sufficient properties which satisfy the proofs for the compliance of the safety objectives at that time. In recent years the validation period of transport approval certificates for manufactured, loaded and stored packages were discussed among authorities and applicants. A case dependant system of 3, 5 and 10 years was established. There are consequences for the safety cases in the Package Design Safety Report including evaluation of long term behavior of components and specific operating procedures of the package. Present research and knowledge concerning the long term behavior of transport and storage cask components have to be consulted as well as experiences from interim cask storage operations. Challenges in the safety assessment are e.g. the behavior of aged metal and elastomeric gaskets under IAEA test conditions to ensure that the results of drop tests can be transferred to the compliance of the safety objectives at the time of transport after the interim storage period. T2 - PATRAM 2013 - 17th International symposium on the packaging and transportation of radioactive materials CY - San Francisco, CA, USA DA - 18.08.2013 KW - Storage KW - Transport KW - Lagerung KW - Verpackung KW - Radioactive material PY - 2013 SP - 1 EP - 9 PB - Omnipress AN - OPUS4-30159 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Wille, Frank A1 - Wolff, Dietmar A1 - Droste, Bernhard A1 - Völzke, Holger A1 - Baden, M. T1 - German approach and feedback on experience of transportability of SNF packages after interim storage N2 - In Germany, the concept of dry interim storage of spent fuel in dual purpose metal casks is implemented, currently for periods of up to 40 years. The casks being used have an approved package design in accordance with the international transport regulations. The license for dry storage is granted on the German Atomic Energy Act with respect to the recently revised 'Guidelines for dry interim storage of irradiated fuel assemblies and heat-generating radioactive waste in casks' by the German Waste management Commission. For transport on public routes between or after long term interim storage periods, it has to be ensured that the transport and storage casks fulfil the specifications of the transport approval or other sufficient properties, which satisfy the proofs for the compliance of the safety objectives at that time. In recent years, the validation period of transport approval certificates for manufactured, loaded and stored packages were discussed among authorities and applicants. A case dependent system of 3, 5 and 10 years was established. There are consequences for the safety cases in the Package Design Safety Report, including evaluation of long term behaviour of components and specific operating procedures of the package. The present research and knowledge concerning the long term behaviour of transport and storage cask components have to be consulted as well as experiences from interim cask storage operations. Challenges in the safety assessment are e.g. the behaviour of aged metal and elastomeric gaskets under IAEA test conditions to ensure that the results of drop tests can be transferred to the compliance of the safety objectives at the time of transport after the interim storage period. Assessment methods for the material compatibility, the behaviour of fuel assemblies and the aging behaviour of shielding parts are issues as well. This paper describes the state of the art technology in Germany, explains recent experience on transport preparation after interim storage and points out arising prospective challenges. KW - Radioactive material storage KW - Dry storage KW - Interim storage KW - Cask design KW - Radioactive material transport KW - Regulation KW - Operating procedures KW - Package KW - Safety KW - Storage KW - Transport KW - Lagerung KW - Spent fuel PY - 2014 DO - https://doi.org/10.1179/1746510914Y.0000000064 SN - 1746-5095 SN - 1746-5109 SN - 0957-476X VL - 25 IS - 2 SP - 55 EP - 59 PB - Ramtrans Publ. CY - Ashford AN - OPUS4-33834 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Birk, A. M. A1 - Otremba, Frank A1 - Gonzales, F. A1 - Prabhakaran, A. A1 - Borch, Jörg-Peter A1 - Bradley, I. A1 - Bisby, L. ED - de Rademaeker, E. ED - Schmelzer, P. T1 - Fire testing of total containment pressure vessels N2 - Full engulfment fire tests have been conducted on total containment pressure vessels filled to 50% and 98 % capacity with water. The tests included an unprotected tank and tanks with two different levels of thermal protection. Total containment in this context means there was no pressure relief device. The tests were conducted with 1/3rd linear scale rail tank cars similar to the DOT 111 tank cars used in North America. The 2.4 m3 model tanks were subjected to 100 % engulfing fires fuelled by liquid propane. The fire heat flux was approximately 80 % by radiation and 20 % by convection with a total heat flux to a cool surface of approximately 100 kW/m2. T2 - 15th International Symposium on loss prevention and safety promotion (loss 2016) CY - Freiburg, Germany DA - 05.06.2016 KW - fire testing KW - hazmat tanks KW - integrity PY - 2016 SN - 978-88-95608-39-6 DO - https://doi.org/10.3303/CET1648047 VL - 48 SP - 277 EP - 282 PB - AIDIC CY - Milano, Italy AN - OPUS4-36361 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Bradley, I. A1 - Otremba, Frank A1 - Birk, A. M. A1 - Bisby, L. T1 - Novel equipment for the study of pressure vessel response to fire N2 - Pressurisation of full-containment pressure vessels in fire is known to be driven by thermal stratification. The predominant mode of heat transfer to the contents (convection from the shell to the liquid phase) results in formation of „hot“ boundary layers. Sub-cooled boiling may also be present. The warm layer rises to the surface through buoyancy and bubble flow, increasing the surface of the liquid above that of the bulk temperature, and hence driving a pressure rise. For reliable prediction of the complex effects governing vessel pressurization a three-dimensional numerical model is required. Work is being undertaken on such a model by other institutions in cooperation with this project. T2 - ASME 2016 CY - Phoenix, Arizona, USA DA - 11.11.2016 KW - Vessels KW - Novel equipment PY - 2016 AN - OPUS4-38433 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wille, Frank A1 - Moutarde, M. A1 - Apel, Andreas A1 - Ballheimer, Viktor A1 - Sterthaus, Jens T1 - Recent developments in standards and IAEA guidance material for package load attachment points N2 - For transport package design and operation according to IAEA regulations, the package shall be securely stowed and its retention system shall be capable to withstand load conditions of routine transport. The supporting IAEA Advisory Material SSG-26 provides information how to do that. Up to now package designers in different countries use other load factors for the design of attachment points than those specified in the IAEA guidance material. In particular the acceleration values vary between different countries and lead to difficulties during the validation of foreign approval certificates. Therefore the IAEA started a discussion process to review the existing guidance text. An international working group was constituted in 2013. Representatives came from different stakeholders, e.g. transport operators, competent authorities and modal organizations. The discussions concluded especially on the transport conditions which has to be considered for stowage design, including on the one hand the relevance of the load factors used for strength and fatigue analysis and on the other hand the criteria which have to be considered for the attachment points. Another standard with relevance to the load attachment of packages is ISO 10276. This standard deals with trunnion design, manufacturing and operational aspects. The regular standard revision phase started in 2017. An expert group discussed new state-of-the-art technology and proposed revised text for the ISO standard for international discussion. The paper describes relevant tie-down aspects, gives background argumentation, and tries to support harmonized application of the revised IAEA guidance material and future ISO 10276 standard. T2 - 11th International Conference on the Transport, Storage and Disposal of Radioactive Materials CY - London, UK DA - 15.05.2018 KW - Verzögerungswerte KW - Lastanschlag KW - Trunnion design KW - ISO KW - Retention PY - 2018 SP - 18511, 1 EP - 8 AN - OPUS4-45294 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Debruyne, M. A1 - Eckert, B. A1 - Wille, Frank A1 - Gauthier, F. A1 - Le Bars, I. A1 - Cordier, N. A1 - Jouve, A.-C. T1 - Assessment of safety demonstrations relative to packages containing UF6 N2 - Specific attention should be paid on safety demonstrations transmitted by applicants in the case of approval request for the package designs containing enriched UF6. Concerning the shipment of enriched UF6, the package designs consist in general of a filled 30B cylinder surrounded by an overpack. The description of the content, considering the UF6 origin, i.e. natural or reprocessed, shall be clearly justified especially when the UF6 isotopic composition exceeds the limits specified in ASTM standards. Concerning the containment of the UF6, the applicant shall demonstrate in all conditions of Transport the leak-tightness of the valve and plug of the cylinders filled with enriched UF6. In this regard, when justifications are based on numerical calculations, the absence of contact between These components of the cylinder and the internal surfaces of the overpack after the regulatory drop tests shall be shown. In particular, absence of contact between the valve and any other component of the packaging shall be confirmed to respect the current IAEA regulations [3]. If complementary calculations show a contact between the plug and the internal surfaces of the overpack, additional tests are required to confirm that the strength resulting from this contact will not affect the plug leak-tightness. It can be noticed that the future revision of the IAEA regulations will include additional provision in case of contact of the plug with any other component of the packaging. In addition, the applicant shall demonstrate that the melting temperature of the valve, including the tinned joint, will not be exceeded during the regulatory fire test. Furthermore, the representativeness of the ballast used to simulate the behaviour of the UF6 loaded within the cylinder shall be justified if drop tests are performed. Finally, specific provisions relative to the use of plugs and the maintenance of cylinders should be included in the safety analysis reports. T2 - 11th International Conference on the Transport, Storage and Disposal of Radioactive Materials CY - London, UK DA - 15.05.2018 KW - Uranhexaflourid KW - Package safety KW - Valve KW - Drop testing KW - Radioactive material PY - 2018 SP - 18523, 1 EP - 8 AN - OPUS4-45295 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Przondziono, R. A1 - Timothy, J.J. A1 - Nguyen, M. A1 - Weise, Frank A1 - Breitenbücher, R. A1 - Meschke, G. A1 - Meng, Birgit T1 - Vorschädigungen in Beton infolge zyklischer Beanspruchungen und deren Auswirkung auf Transportprozesse im Hinblick auf eine schädigende AKR N2 - Auf Grundlage der Zielsetzung der Forschergruppe 1498 beschäftigt sich dieser Beitrag mit den Auswirkungen einer zyklischen mechanischen Belastung im Vierpunktbiegeversuch auf das Transportverhalten in Betongefüge. Hierzu wurde zunächst die Degradation des Mikrogefüges mittels Ultraschallmessungen sowie rissmikroskopischen Untersuchungen an Dünnschliffen charakterisiert. Mit dem Ziel der numerischen Modellbildung wurden Untersuchungen zum Wassereindringverhalten durchgeführt. Es wurden u. a. das Wassereindringverhalten über die Zeit und der Einfluss von Vorschädigungen experimentell geprüft. Basierend auf den gewonnenen Erkenntnissen zu den Einzelprozessen des Ionentransports in poröses Gefüge wurde ein mikromechanisches Mehrskalenmodell entwickelt, welches es ermöglicht, die Wirkung der Vorschädigung auf gekoppelte Feuchte- und Ionentransportprozesse vorherzusagen. Das Modell berücksichtigt die Topologie und räumliche Verteilung der Mikrorisse und deren Einfluss auf die Ionendiffusivität. Die numerische Simulation liefert bei anisotroper Verteilung der Mikrorisse eine erhöhte Alkali-Eindringtiefe. ---------------------------------------------------------------------------------------------------------------------------------- According to the goals of the research group 1498, this paper deals with the effects of cyclic flexural loading in a four-point bending test on the fluid transport processes within a concrete structure. Therefore, the degradation of the microstructure is characterized through ultrasonic wave measurements as well as microscopic crack analysis. In order to numerically model these processes, experiments on the penetration behavior of water into the concrete were carried out. The penetration behavior over time as well as the influence of degradation on the water transport were investigated. To predict the influence of concrete degradation on alkali diffusivity, a multi-scale continuum micromechanics model is incorporated into the numerical model, which accounts for the topology and the three-dimensional distribution of microcracks. As expected, the numerical simulation predicts larger alkali-penetration in pre-damaged concrete. Regarding the micro-crack distribution, an anisotropic distribution of micro-cracks tangential to the direction of the alkali and water flux increases their penetration depth. KW - Alkali-Kieselsäure-Reaktion KW - Baustoffe KW - Degradation KW - Ionentransport KW - Mikromechanik KW - Modellierung KW - Straßenbeton KW - Transportprozesse KW - Vorschädigung KW - zyklische Belastung KW - Korrosion KW - Versuche KW - Fahrbahn KW - Cyclic loading KW - Transport process KW - Schädigende AKR KW - ASR damage PY - 2015 DO - https://doi.org/10.1002/best.201400095 SN - 0005-9900 SN - 1437-1006 VL - 110 IS - 1 SP - 3 EP - 12 PB - Ernst CY - Berlin AN - OPUS4-33039 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Weise, Frank A1 - Kind, Thomas A1 - Stelzner, Ludwig A1 - Wieland, M. T1 - Dunkelfärbung der Betonfahrbahndecke im AKR-Kontext - Ursachenanalyse mit innovativer Prüftechnik T1 - Dark Dyeing of the Concrete Pavement in the AKR Context: Root Cause Analysis with innovative Testing Technology N2 - Die AKR-Schadensevolution von Betonfahrbahndecken ist in der Anfangsphase durch eine Dunkelfärbung der Oberfläche im Fugenbereich gekennzeichnet. Es wird vermutet, dass eine erhöhte Durchfeuchtung der Betonrandzone ursächlich für diese Erscheinung ist. Vor diesem Hintergrund wurde exemplarisch eine Fahrbahnplatte eines repräsentativen Bundesautobahnabschnitts systematisch mit verschiedenartiger zerstörungsfreier Prüftechnik vor Ort untersucht. Die Ergebnisse der zunächst erfolgten großflächigen Durchmusterung mit Radar zeigen, dass in den Bereichen mit einer Dunkelfärbung der Betonfahrbahndecke erhöhte Laufzeiten der Radarimpulse zwischen der Oberfläche und der Rückseite der Betonfahrbahndecke auftreten, was auf eine erhöhte integrale Durchfeuchtung der Betonfahrbahndecke schließen lässt. Vertiefend durchgeführte NMR-Feuchtemessungen in der Betonrandzone zeigen eine gute Korrelation zwischen erhöhtem Feuchtegehalt und der dunkel gefärbten Fahrbahnoberfläche. Die Ergebnisse beider zerstörungsfreien Prüfmethoden lassen den Schluss zu, dass die Betonfahrbahndecke in der Nähe des Fugenkreuzes eine höhere Durchfeuchtung als im Bereich der Querscheinfuge aufweist. Die geringste Durchfeuchtung besitzt die Betonfahrbahndecke in der Plattenmitte. Die mit den zerstörungsfreien Prüfverfahren ermittelten Befunde stimmen prinzipiell gut mit den punktuell mittels Darr-Wäge-Verfahren an Bohrmehlproben gewonnenen Ergebnissen überein. N2 - Darkening of the surface within alkali-silica reaction context - Root cause analysis with non-destructive measurement methods The damage evolution in concrete pavements due to alkali-silica reaction is characterized in the initial phase by a darkening of the surface along joint regions. It is generally assumed that an increased moisture content of the concrete boundary zone is responsible for this visual appearance. Against this background, a concrete pavement slab of a representative German motorway section was systematically investigated in-situ using different non-destructive measurement methods. The results of the high-resolution, planar radar showed an increased time of flight of the radar pulse between the pavement surface and the base of the concrete slab in the darkened areas. This indicated that the overall moisture content is increased near joints in the slab. Additional NMR moisture measurements in the concrete boundary zone confirmed the correlation between increased moisture content and the dark-colored surface of the concrete pavement. The results of both non-destructive measurement methods indicated that the moisture content near the intersection of two joints was higher than the moisture content near the area around the transverse joint. The lowest moisture content was measured in the center of the concrete pavement slab. The results obtained with the two non-destructive testing methods were in overall good agreement with moisture measurements of boring dust analyzed using the gravimetric method. KW - Betonfahrbahndecke KW - Alkali-Kieselsäure-Reaktion KW - Feuchtemessung KW - Radar KW - Nuclear Magnetic Resonance KW - ZfP PY - 2018 DO - https://doi.org/10.1002/best.201800020 SN - 0005-9900 SN - 1437-1006 VL - 113 IS - 9 SP - 647 EP - 655 PB - Wilhelm Ernst & Sohn, Verlag für Architektur und technische Wissenschaften GmbH & Co. KG CY - Berlin AN - OPUS4-46173 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - RPRT A1 - Weise, Frank A1 - Oesch, T. A1 - Wilsch, Gerd A1 - Sigmund, S. A1 - Hünger, K.-J. A1 - Kositz, M. T1 - Analyse des gefügeabhängigen Löslichkeitsverhaltens potenziell AKR-empfindlicher Gesteinskörnungen T1 - Analysis of the microstructure depending solubility behavior of potential ASR sensitive aggregates N2 - Das gefügeabhängige Löslichkeitsverhalten wurde an folgenden vier Gesteinskörnungen unterschiedlicher Alkaliempfindlichkeitsklassen untersucht: • GK1 (EIII-S): quarzreicher Kies • GK2 (EIII-S): Grauwacke (Splitt) • GK3 (EI-S): Quarz-Feldspat-Porphyr (Splitt) • GK4 (EI-S): sandsteinreicher Kies DiePorenstrukturanalyse erfolgte sowohl an Einzelkörnern mittels vergleichender 3D-CT und BET- Untersuchungen als auch an Korngemengen der einzelnen Kornfraktionen (außer Fraktion 16/22 mm) über die Wasseraufnahme und mit BET. Für die Visualisierung und Quantifizierung der von außen zugänglichen Oberflächenanteile der Einzelkörner wurde ein Softwaretool entwickelt, erprobt und erfolgreich angewandt. Es gelang so u.a. den Nachweis zu erbringen, dass die gebrochenen Einzelkörner der Grauwacke und des Rhyoliths einen deutlich geringeren von außen zugänglichen Oberflächenanteil als die gleichartigen Gesteinskörner aus dem Kies besitzen. Aufgrund der limitierten Ortsauflösung der 3D-CT von 11 bis 16,5 μm wurde mit BET eine um drei Zehnerpotenzen höhere spezifische Oberfläche ermittelt. Zu den Porositätsuntersuchungen an den Korngemengen sei angemerkt, dass zum Teil gegenläufige Trends zwischen offener Porosität und spezifischer Oberfläche festgestellt wurden. Dieses ist beim Bezug des bei den Löseversuchen in 0,1 M KOH mit definierter NaCl-Zugabe aus der Gesteinskörnung gelösten SiO2 und Al2O3 von zentraler Bedeutung. Bei den Löseversuchen an den fraktionsspezifischen Korngemengen selbst zeigte sich, dass die stufenweise Erhöhung des NaCl-Gehalts von 0 auf 10 M.-% im Eluat eine erhöhte SiO2-Löslichkeit und eine verminderte Auslaugung von Al2O3 zur Folge hat. Auffallend war hierbei, dass die Al2O3-Löslichkeit bei GK4 ohne und mit geringer NaCl-Zugabe die mit Abstand höchsten Werte annimmt. Bei den zusätzlich durchgeführten Löseversuchen an den tomografierten Einzelkörnern in 1 M KOH-Lösung mit Zugabe von 1 M.-% NaCl zeigte sich, dass nur vereinzelt bei den untersuchten Gesteinsarten eine Korrelation zwischen dem SiO2- bzw. Al2O3-Gehalt im Eluat und der absoluten BET-Oberfläche nachweisbar ist. Dies ist vermutlich darauf zurückzuführen, dass neben der Oberfläche weitere Parameter (z.B. die mineralogische Zusammensetzung der Einzelkörner) das Löseverhalten maßgebend beeinflussen. Bei den parallel zu den Löseversuchen durchgeführten Betonversuchen nach dem ARS 04/2013 zeigte sich, dass die Alkaliempfindlichkeit der GK4 bei beiden Betonversuchen mit Alkalizufuhr unterschiedlich zu bewerten ist. So ist unabhängig von der vorgegebenen pessimalen Betonrezeptur des Fahrbahndeckenbetons ausschließlich bei der Klimawechsellagerung die GK4 als alkaliempfindlich einzustufen. Allerdings konnte der Befund der stark ausgeprägten AKR bei der GK4 mit der Dünnschliffmikroskopie nicht bestätigt werden. Analoges gilt für die Bewertung der Alkaliempfindlichkeit von GK2 mit den Betonversuchen nach der Alkalirichtlichtlinie des DAfStb. So ist auch hier die GK2 nicht im 60 °C-Betonversuch sondern ausschließlich im 40 °C-Betonversuch als alkaliempfindlich einzustufen. Dienach den verschiedenartigen Betonversuchen durchgeführten LIBS-Analysen am Vertikalschnitt der Prüfkörper zeigen, dass im Kernbereich nach dem 60 °C-Betonversuch mit 10 %iger NaCl-Lösung und nach der Klimawechsellagerung mit NaCl-Beaufschlagung annähernd gleich hohe Natrium- und Chloridgehalte vorgefunden werden. Wider Erwarten treten an den beaufschlagten Prüfflächen Abreicherungen von Natrium und Anreicherungen von Chlorid auf. Im 40°C- und 60 °C-Betonversuch wurde das Natrium bis in eine maximale Tiefe von ca. 30 mm bzw. 20 mm ausgelaugt. Die aufbauenden korrelativen Betrachtungen zwischen den Ergebnissen des 60°C Betonversuchs mit Alkalizufuhr und der Löseversuche an den fraktionsspezifischen Korngemengen in 1 M KOH-Lösung mit definierter NaCl-Zugabe sind durchaus vielversprechend. So zeigt sich beispielsweise beim Waschbeton, dass der fraktionsspezifisch gewichtete SiO2-Überschuss im Eluat nach 56 Tagen mit Zugabe von 0,5 M.-% NaCl ohne Bezug auf die BET-Oberfläche zur gleichen Einstufung der vier betrachteten Gesteinskörnungen wie bei den Dehnungen im 60 °C-Betonversuch mit 3 %-iger NaCl-Lösung führt. Außerdem korrelieren die im 60 °C-Betonversuch mit 10 %-iger NaCl-Lösung ermittelten Dehnungen mit dem gewichteten SiO2-Überschuss im Eluat bei Zugabe von 2 M.-% NaCl ohne Bezug auf die BET-Oberfläche. Ausschließlich bei den Betonversuchen nach der Alkali-Richtlinie erwies sich der Bezug des im Eluat ermittelten SiO2-Überschusses auf die BET-Oberfläche als zielführend. Aufgrund des Potenzials der Löseversuche mit NaCl-Zugabe für die Bewertung der Alkaliempfindlichkeit der Gesteinskörnung im Fahrbahndeckenbeton wird empfohlen, die vergleichenden Untersuchungen zwischen den Löseversuchen an Korngemischen der einzelnen Fraktionen und den Betonversuchen nach dem ARS 04/2013 mit einer möglichst hohen Anzahl an Gesteinskörnungen und einem präzisierten Untersuchungsumfang fortzuführen. N2 - The following four aggregates (GK) of varying grades of alkali sensitivity were examined for their microstructure-dependent solubility behavior: • GK1 (EIII-S) gravel with high quarz content • GK2 (EIII-S) greywacke (crushed stone) • GK3 (EI-S) quarz-feldspar-porphyry (crushed stone) • GK4 (EI-S) gravel with high sandstone content Pore structure analysis was carried out both on single grains using comparative 3D-CT and BET tests, and on grain samples of individual grain fractions (excluding the 16/22 mm fraction) using water absorption and BET. A software tool for visualizing and quantifying the externally accessible surfaces of single grains was developed, tested and successfully applied. This enabled us, among other things, to prove that single broken grains of greywacke and rhyolite have a much smaller externally accessible surface than grains of gravel of the same aggregate fraction. Due to the 3D-CT’s limited spatial resolution of 11 to 16.5 μm, BET was used to determine a two to three powers of ten higher specific surface. In relation to the porosity tests of the grain samples, it should be noted that in some cases, counterdirectional trends between open porosity and specific surface were determined. This is of central importance in relation to the SiO2 and Al2O3 dissolved from the aggregate in the solubility tests in 1 M KOH with defined addition of NaCl. The solubility tests on the grain samples of specific fractions showed that the gradual increase of the NaCl content in the eluate from 0 to 10 M.-% resulted in increased SiO2 solubility and reduced leaching of Al2O3. It was striking in this context that the solubility of Al2O3 in GK4 with no or little addition of NaCl gives by far the highest values. The additional solubility tests carried out on single grains, that were previously subjected to CT testing, in 1 M KOH solution with 1 M.-% added NaCl showed that in the types of aggregate examined, a correlation between the SiO2 and Al2O3 in eluate and the absolute BET surface is only occasionally demonstrable. This is probably due to the fact that solubility behavior is decisively influenced by other parameters in addition to the surface (e.g. by the mineralogical composition of individual grains). The concrete tests according to ARS 04/2013 carried out parallel to the solubility tests showed that GK4’s alkali sensitivity in both concrete tests with added alkali must be evaluated differently. For example, independent of the prescribed pessimal road surface concrete formula, GK4 can only be classified as alkali sensitive under cyclic storage. However petrographic microscopy could not confirm the findings of very marked ASR in GK4. The same applies to the evaluation of alkali sensitivity in GK2 with the concrete tests according to the German Committee for Structural Concrete (DAfStb)’s Alkali Guidelines. In this case too, GK2 should not be classified as alkali sensitive in 60 °C concrete testing, but only in 40 °C concrete testing. The LIBS analyses carried out on the vertical cross-section of the test specimens after the various concrete tests showed that almost equally high sodium and chloride levels were found in the core area after the 60 °C concrete prism test with 10 % NaCl solution and after cyclic storage with NaCl application. Contrary to expectations, the surfaces of samples after NaCl application showed a decrease in sodium and an increase in chloride. In the 40°C and 60°C concrete prism tests, sodium was depleted up to a maximum depth of approx. 30 mm and 20 mm respectively. Subsequent correlative observations between the findings of the 60°C concrete prism test with alkali application, and the solubility tests on the samples of specific grain fractions in 1 M KOH solution with defined NaCl addition, are very promising. In the case of exposed aggregate concrete, for example, the fraction-specific weighted excess SiO2 to in the eluate after 56 days with added 0.5 M.-% NaCl unrelated to the BET surface results in the same classification of the four aggregates examined as the expansions in the 60 °C concrete prism test with 3% NaCl solution. In addition, the expansions found in the 60 °C concrete prism test with 10% NaCl solution correlated with the weighted excess SiO2 in eluate with added 2 M.-% NaCl without relation to the BET surface. Only in the case of the concrete test in accordance with the Alkali Guidelines did the relationship of the excess SiO2 in the eluate to the BET surface prove to be productive. Due to the potential of the solubility test with added NaCl for the evaluation of alkali sensitivity of aggregates in road surface concrete, we recommend continuing with comparative tests between solubility tests of grain samples of the various fractions and the concrete tests in accordance with ARS O4/13 with the greatest possible number of aggregates and a precisely defined investigation scope. KW - LIBS KW - Betonfahrbahndecke KW - Alkali-Kieselsäure-Reaktion KW - Gesteinskörnung KW - Alkaliempfindlichkeit KW - 3D-CT KW - Tausalzeintrag PY - 2021 UR - https://nbn-resolving.org/urn:nbn:de:hbz:opus-bast-25832 UR - https://bast.opus.hbz-nrw.de/frontdoor/index/index/docId/2583 SN - 978-3-95606-648-1 SN - 0943-9323 VL - S 165 SP - 1 EP - 111 PB - Fachverlag NW in der Carl Ed. Schünemann KG CY - Bremen AN - OPUS4-54755 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hofmann, Detlef A1 - Basedau, Frank A1 - Heidenreich, F. A1 - Herten, M. T1 - Verwendung faseroptischer Messtechnik im Zuge wiederholter Eignungsprüfungen an Verpressankern N2 - Im Rahmen des Ausbaus des Dortmund-Ems-Kanals wurden an der Schleuse Gleesen Forschungsanker installiert, die Rückschlüsse auf das Tragverhalten in Folge des chemischen Angriffs kalklösender Kohlensäure geben sollen. Die Forschungsanker werden seit der Erstellung im Jahr 2017 mit verteilter faseroptischer Sensorik während der jährlichen Eignungsprüfungen untersucht. Die Ergebnisse der Jahre 2017 bis 2019 werden im Folgenden dargestellt. T2 - Messen in der Geotechnik 2020 CY - Braunschweig, Germany DA - 20.02.2020 KW - Faseroptische Sensorik KW - Rayleigh Rückstreuung KW - Verpressanker KW - Chemischer Angriff KW - Rissbildung PY - 2020 SN - 978-3-948141-02-8 DO - https://doi.org/10.24355/dbbs.084-201912181435-0 IS - 110 SP - 297 EP - 323 AN - OPUS4-51687 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Przondziono, R. A1 - Timothy, J. J. A1 - Weise, Frank A1 - Krütt, Enno A1 - Breitenbücher, R. A1 - Meschke, G. A1 - Hofmann, M. T1 - Degradation in concrete structures due to cyclic loading and its effect on transport processes - Experiments and modeling N2 - According to the objectives of the research group 1498, this paper deals with degradation effects in concrete structures that are caused by cyclic flexural loading. The goal is to determine their influence on the fluid transport processes within the material on the basis of experimental results and numerical simulations. The overall question was, to which extent the ingress of externally supplied alkalis and subsequently an alkali-silica reaction are affected by such modifications in the microstructure. Degradation in the concrete microstructure is characterized by ultrasonic wave measurements as well as by microscopic crack analysis. Furthermore, experiments on the penetration behavior of water into the investigated materials were performed. The penetration behavior into predamaged concrete microstructures was examined by the classical Karsten tube experiment, nuclear magnetic resonance method, and time domain reflectometry techniques. In order to create an appropriate model of the material's degradation on the water transport, the Darcy law was applied to describe the flow in partially saturated concrete. Material degradation is taken into account by an effective permeability that is dependent on the state of degradation. This effective permeability is obtained by the micromechanical homogenisation of the flow in an Representative Elementary Volume (REV) with distributed ellipsoidal microcracks embedded in a porous medium. The data gained in the microscopic crack analysis is used as input for the micromechanical model. Finite element simulations for unsaturated flow using the micromechanical model were compared with the experimental results showing good qualitative and quantitative agreement. KW - Alkali ingress KW - Alkali-silica reaction KW - Computational model for unsaturated flow KW - Cyclic loading KW - Degradation KW - Micromechanics model KW - Transport processes PY - 2017 DO - https://doi.org/10.1002/suco.201600180 SN - 1751-7648 SN - 1464-4177 VL - 18 IS - 4 SP - 519 EP - 527 PB - Ernst & Sohn AN - OPUS4-41008 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Spilker, A. A1 - Stelzner, Ludwig A1 - Weise, Frank A1 - Wieland, M. T1 - Analyse der thermischen Dehnung von Fahrbahndeckenbetonen aus dem BAB-Netz N2 - Die Kenntnis von Materialeigenschaften spielt bei der Entwicklung oder Optimierung von Betonen und Bauweisen für den Straßenbau sowie der Qualitätssicherung eine bedeutende Rolle. Gleichermaßen bilden physikalische Materialkennwerte die Grundlage für die rechnerische Dimensionierung und die Restsubstanzbewertung von Betonfahrbahndecken. Eine relevante Kenngröße bei der Untersuchung thermisch induzierter Spannungs- und Verformungszustände stellt der thermische Ausdehnungskoeffizient dar. Im Zuge der systematischen Weiterentwicklung der rechnerischen Dimensionierung, aber auch im Zusammenhang mit der gezielten Verbesserung der Gebrauchseigenschaften von Betonfahrbahndecken gilt es zu hinterfragen, ob lastunabhängige Formänderungseigenschaften der verwendeten Betone aktuell ausreichend Beachtung finden, ob allgemeine Literaturwerte für die heutigen Fahrbandeckenbetone stets Gültigkeit besitzen und ob deren Implementierung in numerische Modelle zu realitätsnahen Vorhersagen führt. Für eine empirische Herangehensweise ist die Verfügbarkeit adäquater Prüfverfahren von entscheidender Bedeutung. In Deutschland existiert aktuell jedoch kein standardisiertes oder genormtes Verfahren für die prüftechnische Bestimmung des thermischen Ausdehnungskoeffizienten von Beton. Daher wurden unter Beachtung straßenbauspezifischer Gesichtspunkte zwei Prüfansätze entwickelt, die in diesem Beitrag vorgestellt sowie hinsichtlich möglicher Messunsicherheiten und Messungenauigkeiten diskutiert werden. Außerdem werden ausgewählte Ergebnisse aus Analysen an Bestandsbetonen aus dem BAB-Netz dargestellt. Im Ergebnis sollen die Untersuchungen einen Beitrag zur Schaffung der prüftechnischen Voraussetzungen für eine abgesicherte Quantifzierung der thermischen Dehnung von Fahrbahndeckenbetonen leisten. KW - Betonfahrbahndecken KW - Materialkennwerte KW - Thermischer Ausdehnungkoeffizient KW - Prüfverfahren PY - 2020 DO - https://doi.org/10.1002/best.202000044 VL - 116 IS - 1 SP - 26 EP - 34 PB - John Wiley & Sons AN - OPUS4-54967 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Paul, Andrea A1 - Meyer, Klas A1 - Ruiken, Jan-Paul A1 - Illner, M. A1 - Müller, D.-N. A1 - Esche, E. A1 - Wozny, G. A1 - Westad, Frank A1 - Maiwald, Michael T1 - Process spectroscopy in microemulsions — Raman spectroscopy for online monitoring of a homogeneous hydroformylation process N2 - A major industrial reaction based on homogeneous catalysis is hydroformylation for the production of aldehydes from alkenes and syngas. Hydroformylation in microemulsions, which is currently under investigation at Technische Universität Berlin on a mini-plant scale, was identified as a cost efficient approach which also enhances product selectivity. Herein, we present the application of online Raman spectroscopy on the reaction of 1-dodecene to 1-tridecanal within a microemulsion. To achieve a good representation of the operation range in the mini-plant with regard to concentrations of the reactants a design of experiments was used. Based on initial Raman spectra partial least squares regression (PLSR) models were calibrated for the prediction of 1-dodecene and 1-tridecanal. Limits of predictions arise from nonlinear correlations between Raman intensity and mass fractions of compounds in the microemulsion system. Furthermore, the prediction power of PLSR models becomes limited due to unexpected by-product formation. Application of the lab-scale derived calibration spectra and PLSR models on online spectra from a mini-plant operation yielded promising estimations of 1-tridecanal and acceptable predictions of 1-dodecene mass fractions suggesting Raman spectroscopy as a suitable technique for process analytics in microemulsions. KW - Raman KW - Online KW - Chemometrics KW - Hydroformylation KW - Mini-plant KW - Microemulsion PY - 2017 DO - https://doi.org/10.1088/1361-6501/aa54f0 SN - 1361-6501 SN - 0957-0233 VL - 28 IS - 3 SP - 035502-1 EP - 035502-11 PB - IOP Publishing Ltd CY - UK AN - OPUS4-39032 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Meyer, Klas A1 - Paul, Andrea A1 - Ruiken, J.-P. A1 - Westad, Frank A1 - Illner, M. A1 - Müller, D. A1 - Esche, E. A1 - Repke, J.-U. A1 - Maiwald, Michael T1 - Online Spectroscopy in Microemulsions – A Process Analytical Approach for a Hydroformylation Mini-plant N2 - Within the Collaborative Research Center InPROMPT a novel process concept for the hydroformylation of long-chained olefins is studied in a mini-plant, using a rhodium complex as catalyst in the presence of syngas. Recently, the hydroformylation in micro¬emulsions, which allows for the efficient recycling of the expensive rhodium catalyst, was found to be feasible. However, the high sensitivity of this multi-phase system with regard to changes in temperature and composition demands a continuous observation of the reaction to achieve a reliable and economic plant operation. For that purpose, we tested the potential of both online NMR and Raman spectroscopy for process control. The lab-scale experiments were supported by off-line GC-analysis as a reference method. A fiber optic coupled probe of a process Raman spectrometer was directly integrated into the reactor. 25 mixtures with varying concentrations of olefin (1-dodecene), product (n-tridecanal), water, n-dodecane, and technical surfactant (Marlipal 24/70) were prepared according to a D-optimal design. Online NMR spectroscopy was implemented by using a flow probe equipped with 1/16” PFA tubing serving as a flow cell. This was hyphenated to the reactor within a thermostated bypass to maintain process conditions in the transfer lines. Partial least squares regression (PLSR) models were established based on the initial spectra after activation of the reaction with syngas for the prediction of unknown concentrations of 1-dodecene and n-tridecanal over the course of the reaction in the lab-scale system. The obtained Raman spectra do not only contain information on the chemical composition but are further affected by the emulsion properties of the mixtures, which depend on the phase state and the type of micelles. Based on the spectral signature of both Raman and NMR spectra, it could be deduced that especially in reaction mixtures with high 1-dodecene content the formation of isomers as a competitive reaction was dominating. Similar trends were also observed during some of the process runs in the mini-plant. The multivariate calibration allowed for the estimation of reactants and products of the hydroformylation reaction in both laboratory setup and mini-plant. T2 - 4th European Conference on Process Analytics and Control Technology (EuroPACT 2017) CY - Potsdam, Germany DA - 10.05.2017 KW - Microemulsions KW - Process Analytical Technology KW - Reaction Monitoring KW - Online NMR Spectroscopy KW - Online Raman Spectroscopy PY - 2017 SP - 64 EP - 64 CY - Frankfurt a. M. AN - OPUS4-40228 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Paul, Andrea A1 - Ruiken, J.-P. A1 - Meyer, Klas A1 - Westad, Frank A1 - Illner, M. A1 - Müller, D. A1 - Wozny, G. A1 - Maiwald, Michael T1 - Online spectroscopy in microemulsions – A process analytical approach for hydroformylation miniplant II - Calibration and prediction by Raman spectra N2 - The Collaborative Research Center InPROMPT aims to establish a novel process concept for the hydroformylation of long-chained olefins, using a rhodium complex as catalyst in the presence of syngas. Recently, the hydroformylation in micro-emulsions, which allows for the efficient recycling of the expensive rhodium catalyst, was found to be feasible. However, the temperature and concentration sensitive multi-phase system demands a continuous observation of the reaction to achieve an operational and economically feasible plant operation. For that purpose, we tested the potential of both NMR and Raman spectroscopy for process control assistance. The lab-scale experiments were supported by sampling for off-line GC-analysis as reference analytics. The results of the NMR experiments will be part of another contribution. T2 - 11. Kolloquium Arbeitskreis Prozessanalytik CY - Wien, Austria DA - 30.11.2015 KW - Prozessanalytik KW - Process analytical technology KW - Prozess-Spektroskopie KW - Emulsions KW - Hydroformylation KW - Reaction monitoring KW - Raman spectroscopy PY - 2015 SP - 66 EP - 67 PB - Bundesanstalt für Materialforschung und -prüfung (BAM) CY - Berlin AN - OPUS4-38846 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Otremba, Frank A1 - Prabhakaran, A. A1 - Robitaille, A. A1 - Birk, A. M. A1 - Gonzalez III, F. T1 - Rail tank car total containment fire testing: results and observations N2 - The frequent incidences of Non-Accident Releases (NARs) of lading from tank cars have resulted in an increasing interest in transporting hazardous materials in total Containment conditions (i.e., no pressure relief devices). T2 - Proceedings of the 2016 joint rail conference CY - Columbia, SC, USA DA - 12.04.2016 KW - Rail tank containment fire PY - 2016 SN - 978-0-7918-4967-5 SP - 1 EP - 8 AN - OPUS4-35772 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Hea, Y. A1 - Esteban-Fernandez, Diego A1 - Neumann, B. A1 - Bergmann, U. A1 - Bierkandt, Frank A1 - Linscheid, M. W. T1 - Application of MeCAT-Click labeling for protein abundance characterization of E. coli after heat shock experiments N2 - In a proof of concept study, metal-coded affinity tags based on click chemistry (MeCAT-Click) were used to analyze the proteome of Escherichia coli (E. coli) in response to heat stress. This allows high labeling efficiency, high detection sensitivity, and multiplex capabilities, which are pivotal for its application to protein quantification. Two approaches are presented for relative quantification of differentially lanthanide-labeled proteins. The first approach uses isotope-labeling, where ESI-MS was utilized to quantify the differentially labeled proteins from different states of E. coli. With this approach, 14 proteins were found with changed abundance, among them five proteins upregulated. In the second approach, differentially labeled samples were separated by two dimensional gel electrophoresis (2 DE) and scanned by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Comparison of the signal intensities of the different lanthanides was used to quantify different sample states. Based on this information, ESI-MS was used to identify the proteins with different abundance. The sensitivity of LA-ICP-MS allowed us to find one upregulated protein that was nearly invisible by silver staining ("Probable replication endonuclease from retron EC67"). The advantage of this approach is to locate low abundant proteins with differential expression using LA-ICP-MS, which may be overlooked otherwise. Biological significance: This paper demonstrates the successful application of a novel metal labeling strategy to quantify the proteins from complex biological samples. In comparison with former metal labeling strategies, it reduces the steric hindrance and improves the labeling efficiency during the labeling process, which ensure its successful application. This methodology is compatible with both molecular and elemental mass spectrometry. ESI-MS/MS in combination with software-based search allows the identification and relative quantification of labeled proteins. In addition, LA-ICP-MS helps to locate the labeled proteins in 2-DE gels with superior detection capability, thus, target proteins with low abundance can be precisely followed. Its excellent sensitivity allows one to track the proteins of interest that are barely visible by silver staining. KW - Protein quantification KW - Heat shock response KW - Ln-MeCAT-Click labeling KW - nanoLC-ESI-MS/MS KW - 2-D electrophoresis KW - LA-ICP-MS PY - 2016 DO - https://doi.org/10.1016/j.jprot.2015.12.010 SN - 1874-3919 VL - 136 SP - 68 EP - 76 PB - Elsevier B.V. CY - Amsterdam AN - OPUS4-35837 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Bradley, I. A1 - Scarponi, G. E. A1 - Otremba, Frank A1 - Cozzani, V. A1 - Birk, A. M. T1 - Experimental Analysis of a Pressurized Vessel Exposed to Fires: an Innovative Representative Scale Apparatus N2 - A novel deign of test equipment has been commissioned to investigate thermal stratification and boiling during fire exposure of pressure vessels. Extensive temperature measurements and video of the internal conditions during fire exposure are possible, and the equipment has been designed for future compatibility with laser-based velocity measurement techniques. It is expected to generate data large quantities of data that will be of use in validation of two- and three-dimensional CFD models for the prediction of pressure vessel behaviour in fire. Future work will seek to characterize the boundary layer conditions in detail for a range of test fluids, fill levels and fire-induced thermal boundary conditions. Initial tests undertaken during commissioning may indicate that fire exposure of the vessel wall just above the liquid level can have a notable influence on the pressurization rate, by increasing the degree of superheat. Further experimental and modelling work is required to confirm and quantify this effect, or to rebut this conclusion. T2 - ICH 13th International Conference on Chemical and Process Engineering CY - Milan, Italy DA - 28.05.2017 KW - Representative Scale Apparatus KW - Pressurized Vessel, KW - Fire PY - 2017 VL - 57 SP - 1 EP - 6 AN - OPUS4-40663 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Bradley, I. A1 - Scarponi, G. E. A1 - Otremba, Frank A1 - Cozzani, V. A1 - Birk, A. M. T1 - Experimental analysis of a pressurized N2 - Test equipment has been commissioned and proven to work.Initial data on temperatures, and pressurization rates have been collected and are now under analysis. The level of detail of the measurements is suitable for CFD validation. Initial PIV studies were undertaken to measure the velocity field. T2 - ICH 13th International Conference on Chemical and Process Engineering CY - Milan, Italy DA - 28.05.2017 KW - Fire KW - pressurized vessel KW - Representative scale apparatus PY - 2017 AN - OPUS4-40665 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Thomsen-Schmidt, P. A1 - Hasche, K. A1 - Ulm, G. A1 - Herrmann, K. A1 - Krumrey, M. A1 - Ade, G. A1 - Stümpel, J. A1 - Busch, I. A1 - Schädlich, S. A1 - Schindler, A. A1 - Frank, W. A1 - Hirsch, D. A1 - Procop, Mathias A1 - Beck, Uwe T1 - Realisation and metrological characterisation of thickness standards below 100 nm N2 - High-accuracy film thickness measurements in the range below 100 nm can be made by various complex methods like spectral ellipsometry (SE), scanning force microscopy (SFM), grazing incidence X-ray reflectometry (GIXR), or X-ray fluorescence analysis (XRF). The measurement results achieved with these methods are based on different interactions between the film and the probe. A key question in nanotechnology is how to achieve consistent results on a level of uncertainty below one nanometre with different techniques. Two different types of thickness standards are realised. Metal film standards for X-ray techniques in the thickness range 10 to 50 nm are calibrated by GIXR with monochromatised synchrotron radiation of 8048 eV. The results obtained at four different facilities show excellent agreement. SiO2 on Si standards for SE and SFM in the thickness range 6 to 1000 nm are calibrated by GIXR with monochromatised synchrotron radiation of 1841 eV and with a metrological SFM. Consistent results within the combined uncertainties are obtained with the two methods. Surfaces and interfaces of both types of standards are additionally investigated by transmission electron microscopy (TEM). PY - 2004 DO - https://doi.org/10.1007/s00339-003-2273-7 SN - 0947-8396 VL - 78 IS - 5 SP - 645 EP - 649 PB - Springer CY - Berlin AN - OPUS4-17195 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Krause, Martin A1 - Milmann, Boris A1 - Mielentz, Frank A1 - Streicher, Doreen A1 - Redmer, Bernhard A1 - Mayer, K. A1 - Langenberg, K.-J. A1 - Schickert, M. T1 - Ultrasonic Imaging Methods for Investigation of Post-tensioned Concrete Structures: A Study of Interfaces at Artificial Grouting Faults and Its Verification N2 - This paper presents the progress of successful location of grouting faults in tendon ducts with ultrasonic imaging. The examples were obtained in the research group FOR 384 funded by DFG (German Research Foundation). The co-operation of experimental research and modeling allowed imaging and identification of grouted and ungrouted areas of tendon ducts (including strands) in a large test specimen (40 m²). In addition to the criteria for indicating grouting faults in post-tensioned ducts known until now the phase evaluation of reflected ultrasonic pulses is described. Experiments and modeling of wave propagation are presented for reflections at metal plates in concrete (thickness range 0.5 mm to 40 mm) and for tendon ducts including strands. The main part of the progress was achieved by automated measurements using dry contact transducers, 3D-SAFT reconstruction including phase evaluation and modeling considering wave propagation for typical elastic parameters and exact experimental site conditions. The results for shear waves as well as for pressure waves are compared in the frequency range from 50 kHz to 120 kHz. KW - Non-destructive testing KW - Tendons KW - Prestressed concrete bridges KW - Ultrasonic echo KW - Reconstruction calculation KW - 3D-SAFT KW - Modeling (EFIT) PY - 2008 DO - https://doi.org/10.1007/s10921-008-0033-5 SN - 0195-9298 SN - 1573-4862 VL - 27 IS - 1-3 SP - 67 EP - 82 PB - Plenum Press CY - New York, NY AN - OPUS4-17922 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - RPRT A1 - Müller, H. S. A1 - Fenchel, M. A1 - Wiggenhauser, Herbert A1 - Maierhofer, Christiane A1 - Krause, Martin A1 - Gardei, André A1 - Mielentz, Frank A1 - Milmann, Boris A1 - Röllig, Mathias A1 - Wöstmann, Jens T1 - Zerstörungsfreie Ortung von Gefügestörungen in Betonbodenplatten N2 - Das Ziel des Forschungsvorhabens „Zerstörungsfreie Ortung von Gefügestörungen in Betonbodenplatten“ bestand in der Entwicklung eines Untersuchungskonzepts zur sicheren Ortung und Erfassung von Gefügestörungen in einseitig zugänglichen Betonplatten durch den kombinierten Einsatz verschiedener zerstörungsfreier Prüfverfahren. Hierfür wurde die Leistungsfähigkeit der folgenden Messverfahren hinsichtlich ihrer Aussageschärfe, Anwendungsgrenzen und Messgeschwindigkeit bei praxisnahen Randbedingungen untersucht: - Impakt-Echo, manuelle Impaktauslösung - Impakt-Echo, automatisierte Impaktauslösung - Ultraschall-Echo mit multistatischem Array - Impuls-Thermografie - Radar Als Versuchskörper dienten sechs liegend hergestellte Betonplatten der Abmessungen 200/200/30 cm aus zwei verschiedenen Betongüten und mit unterschiedlichem Bewehrungsgehalt (Bewehrungsgrade 0 %, 0 ,9 %, 2 ,6 %), von denen vier Platten auf trockenem und zwei Platten auf ständig nass gehaltenem Sand gelagert waren. Alle sechs Platten enthielten jeweils dieselben künstlich eingebrachten Fehlstellen: vier quadratische Kiesnester in unterschiedlicher Tiefe mit Kantenlängen zwischen 10 und 15 cm sowie drei oberflächennahe Hohlstellen (Ø 4/6/8 cm). Zur Erfassung eines möglichen Einflusses des Betonalters wurden die Messungen 4 Tage, 28 Tage sowie 180 Tage nach Herstellung der Platten durchgeführt. Um aus den Untersuchungen einen breiten Nutzen für die Praxis zu erzielen, basierten die eingesetzten Messverfahren auf handelsüblichen Geräten, welche jedoch bezüglich ihres Messprinzips und insbesondere der Datenerfassung und -auswertung weiterentwickelt wurden. Die Fehlstellengröße wurde bewusst klein gewählt. Mit Ausnahme des manuellen Impakt-Echo-Verfahrens, mit welchem unter Verwendung der Originalsoftware des Herstellers keine Fehlstellen nachweisbar waren, zeigten sich alle Messverfahren geeignet, unter verschiedenen Randbedingungen Gefügestörungen zu lokalisieren. Insgesamt wurde jeder Fehlstellentyp von zumindest einem Verfahren bei mindestens zwei Versuchskörpern detektiert. Es konnten jedoch an keiner Betonplatte mit einem einzelnen Messverfahren alle vorhandenen Fehlstellen an allen Messterminen geortet werden. Am häufigsten wurden die beiden großen oberflächennahen Fehlstellen (Hohlstelle Ø 8 cm, Kiesnest 10 cm) erkannt. Am schwersten zu lokalisieren waren die kleine Hohlstelle mit 4 cm Durchmesser sowie die beiden auf der Unterseite gelegenen Kiesnester. Die Untersuchungen zeigen, dass für eine erfolgreiche Anwendung zerstörungsfreier Messverfahren in der Praxis die Auswahl des am besten geeigneten Verfahrens bzw. einer Kombination verschiedener Verfahren jeweils auf die vorliegende Problemstellung abgestimmt sein muss. Für Betonbodenplatten mit hohem Feuchtegehalt (junger Beton) oder starker Bewehrung ist entweder das Ultraschall- oder das Impakt-Echo-Verfahren geeignet. Das Ultraschall-Verfahren wird von hohen Bewehrungsgehalten zwar stärker beeinflusst als das Impakt-Echo-Verfahren, besitzt aber eine bessere Auflösung und ermöglicht auch im oberflächennahen Bereich eine quantitative Bestimmung der Fehlstellentiefe. Das Impakt-Echo-Verfahren kann wegen der niederfrequenten Impulsanregung Fehlstellen erst in größeren Tiefen und mit schlechterer Auflösung nachweisen, ist aber ideal geeignet zur Bestimmung der Plattendicke aufgrund seines signifikanten Rückwandechos. Sowohl das Radar-Verfahren als auch die Impuls-Thermografie können bei hohen Feuchte- und Bewehrungsgehalten nur sehr oberflächennah eingesetzt werden. Bei trockenem Beton und geringen bis mittleren Bewehrungsgehalten liefert das Radar-Verfahren sehr gute Ergebnisse. In kurzer Zeit ermöglicht es eine flächendeckende Ortung der Tiefenlage und Größe von Inhomogenitäten bei guter Auflösungsgenauigkeit. Vorhandene Bewehrung wird deutlich abgebildet, kann aber darunterliegende Fehlstellen verschatten. Alternativ kann die Impuls-Thermografie für die Ortung oberflächennaher Gefügestörungen eingesetzt werden. Das Verfahren eignet sich insbesondere bei Oberflächen, die nicht direkt zugänglich sind, da zwischen Infrarotkamera und Messobjekt nur Sichtkontakt bestehen muss. Die Betongüte hatte bei keinem eingesetzten Verfahren einen erkennbaren Einfluss auf die Messergebnisse. Streng genommen ist dies jedoch nur für den Einfluss des Wasserzementwertes, der Zementart und des Zementgehalts bei gleichbleibender Sieblinie und gleicher Kornart gültig. Bei Verwendung von Leichtzuschlag sind abweichende Ergebnisse denkbar. PY - 2010 SN - 978-3-410-65075-1 SN - 0171-7197 IS - 589 SP - 1 EP - 88 PB - Beuth CY - Berlin AN - OPUS4-22699 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Weise, Frank A1 - Patitz, G. A1 - Redmer, Bernhard A1 - Hübner, M. A1 - Maier, Bärbel A1 - Ewert, Uwe ED - Grassegger-Schön, G. T1 - Kombination zerstörungsfreier Prüfverfahren zur Strukturaufklärung beim Säulenjoch der Heiligen Halle am Markt von Priene T2 - 10. Tagung Natursteinsanierung CY - Stuttgart, Deutschland DA - 2004-03-19 KW - Baudenkmäler KW - Strukturaufklärung KW - Zerstörungsfreie Prüfung KW - Videoskopie KW - Radar KW - Radiografie PY - 2004 SN - 3-935643-12-8 SP - 99 EP - 107 PB - Siegl CY - München AN - OPUS4-4817 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Weise, Frank A1 - Patitz, G. A1 - Redmer, Bernhard A1 - Hübner, M. T1 - Kombination zerstörungsfreier Prüfverfahren zur Strukturaufklärung beim Markttor von Milet KW - Baudenkmäler KW - Strukturaufklärung KW - Zerstörungsfreie Prüfung KW - Radar KW - Radiografie PY - 2004 VL - 2 SP - 117 EP - 128 PB - Wissenschaftlich-Technische Arbeitsgemeinschaft für Bauwerkserhaltung und Denkmalpflege CY - München AN - OPUS4-4820 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Hasche, K. A1 - Ulm, G. A1 - Herrmann, K. A1 - Krumrey, M. A1 - Ade, G. A1 - Sümpel, J. A1 - Busch, I. A1 - Thomsen-Schmidt, P. A1 - Schädlich, S. A1 - Schindler, A. A1 - Frank, W. A1 - Procop, Mathias A1 - Beck, Uwe T1 - About the calibration of thickness standards on the nanometer scale T2 - 3rd International EUSPEN conference ; 3rd International conference. European Society for Precision Engineering and Nanotechnology ; 4th General meeting. European Society for Precision Engineering and Nanotechnology CY - Eindhoven, The Netherlands DA - 2002-05-26 PY - 2002 SN - 90-386-2883-8 SP - 1 EP - 5 CY - Eindhoven AN - OPUS4-2283 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hasche, K. A1 - Herrmann, K. A1 - Thomsen-Schmidt, P. A1 - Krumrey, M. A1 - Ulm, G. A1 - Ade, G. A1 - Pohlenz, F. A1 - Stümpel, J. A1 - Busch, I. A1 - Schädlich, S. A1 - Frank, W. A1 - Hirsch, D. A1 - Schindler, A. A1 - Procop, Mathias A1 - Beck, Uwe T1 - Ein Beitrag zu kalibrierten Nanometerschichten für unterschiedliche Anwendungsbereiche N2 - Nanotechnologien werden gegenwärtig als leistungsfähige Oberflächentechniken in erheblichem Umfange industriell genutzt. Dabei spielen dünne Schichten und deren Kenndaten eine wesentliche Rolle, z.B. als Röntgenspiegel oder optische und magnetooptische Datenträger. Die Schichtdicke zählt hierbei zu den technologisch wichtigen Parametern. Abgeleitet von Anwenderinteressen, werden für die Röntgenreflektometrie (XRR bzw. GIXR), Elektronenstrahl-Mikroanalyse (EPMA) und Röntgenfluoreszenzanalyse (XRF) einerseits und die Ellipsometrie andererseits zugeschnittene Schichtdickenmaßverkörperungen (SDM) entwickelt, gefertigt und untersucht. Das Ziel ist die Bereitstellung praxistauglicher, kalibrierter SDM, im weiteren Schichtdickennormale (SDN) genannt. SDN sind Maßverkörperungen, für die der Schichtdickenwert mit einer definierten Messunsicherheit bekannt und auf ein metrologisch anerkanntes Längennormal zurückgeführt ist. Berichtet wird über die Herstellung und messtechnische Charakterisierung der beiden spezifischen Varianten von Maßverkörperungen. T2 - 47. Internationales Wissenschaftliches Kolloquium. Technische Universität Ilmenau ; Herbstkonferenz der Gesellschaft für Arbeitswissenschaft ; 6. Workshop Multimedia für Bildung und Wirtschaft CY - Ilmenau, Deutschland DA - 2002-09-23 PY - 2002 UR - http://publica.fraunhofer.de/documents/N-14872.html VL - 47 SP - 568 EP - 569 PB - Techn. Univ. CY - Ilmenau AN - OPUS4-2284 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Koenders, L. A1 - Hasche, K. A1 - Ulm, G. A1 - Krumrey, M. A1 - Ade, G. A1 - Stümpel, J. A1 - Busch, I. A1 - Thomsen-Schmidt, P. A1 - Schädlich, S. A1 - Schindler, A. A1 - Frank, W. A1 - Beck, Uwe A1 - Procop, Mathias T1 - Über die metrologische Charakterisierung von Schichtdicken Standards im Nanometerbereich T2 - 12th Applied Surface Analysis Workshop ; AOFA 12 CY - --- DA - 2002-09-15 PY - 2002 AN - OPUS4-2285 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Habel, Wolfgang A1 - Hofmann, Detlef A1 - Gutmann, Toivo A1 - Basedau, Frank A1 - Molter, M. A1 - Hegger, J. ED - Inaudi, D. T1 - Characterization of bond performance of textiles in cement matrices using fiber optic sensors T2 - Smart structures and materials 2002 - Smart sensor technology and measurement systems CY - San Diego, CA, USA DA - 2002-03-18 KW - Textile reinforced concrete KW - Fibers KW - Concrete KW - Bond KW - Fiber-optic sensors PY - 2002 SN - 0-8194-4442-1 DO - https://doi.org/10.1117/12.472626 SN - 1605-7422 N1 - Serientitel: SPIE proceedings series – Series title: SPIE proceedings series IS - 4694 SP - 253 EP - 258 PB - SPIE CY - Bellingham, Wash. AN - OPUS4-1458 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Hofmann, Detlef A1 - Habel, Wolfgang A1 - Gutmann, Toivo A1 - Basedau, Frank A1 - Molter, M. A1 - Hegger, J. A1 - Will, N. T1 - Untersuchungen an textilbewehrtem Beton PY - 2002 SN - 0025-5300 VL - 44 IS - 5 SP - 194 EP - 198 PB - Carl Hanser Verlag CY - München AN - OPUS4-1474 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Weise, Frank A1 - Patitz, G. A1 - Redmer, Bernhard A1 - Hübner, M. A1 - Ewert, Uwe ED - Grassegger-Schön, G. T1 - Kombination zerstörungsfreier Prüfverfahren zur Strukturaufklärung beim Markttor von Milet T2 - 10. Tagung Natursteinsanierung CY - Stuttgart, Deutschland DA - 2004-03-19 KW - Baudenkmäler KW - Strukturaufklärung KW - Zerstörungsfreie Prüfung KW - Radar KW - Radiografie PY - 2004 SN - 3-935643-12-8 SP - 109 EP - 118 PB - Siegl CY - München AN - OPUS4-4818 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Weise, Frank A1 - Patitz, G. A1 - Redmer, Bernhard A1 - Hübner, M. A1 - Maier, Bärbel A1 - Ewert, Uwe T1 - Kombination zerstörungsfreier Prüfverfahren zur Strukturaufklärung beim Säulenjoch der Heiligen Halle am Markt von Priene KW - Baudenkmäler KW - Strukturaufklärung KW - Zerstörungsfreie Prüfung KW - Videoskopie KW - Radar KW - Radiografie PY - 2004 VL - 2 SP - 97 EP - 116 PB - Wissenschaftlich-Technische Arbeitsgemeinschaft für Bauwerkserhaltung und Denkmalpflege CY - München AN - OPUS4-4819 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Weise, Frank A1 - Hüsken, Götz A1 - Niedack-Nad, Marianne A1 - Wieland, M. T1 - AL Sp-Beton - Präzision des Prüfverfahrens N2 - Für die rechnerische Dimensionierung der Betondecken im Oberbau von Verkehrsflächen für den Neubau sowie die Erneuerung nach RDO Beton 09 ist die statische Spaltzugfestigkeit an der unteren bzw. unteren und oberen Scheibe des Betonzylinders bzw. Bohrkerns entsprechend der Vorgaben der AL Sp-Beton zu bestimmen. Aufgrund der unzureichenden Kenntnis der Präzision dieses Prüfverfahrens wurden mit einem breit aufgestellten Ringversuch die statistischen Kennwerte an Labor- und Bestandsbetonen unter Vergleich- und Wiederholbedingungen auf der Grundlage des „Merkblatts über die statistische Auswertung von Prüfergebnissen" ermittelt. Für eine möglichst gute statistische Absicherung nahmen an dem Ringversuch 13 erfahrene Prüfstellen teil. Zur Abdeckung des vielschichtigen Einsatzes des Prüfverfahrens erfolgte der Ringversuch an acht Prüflosen. Dabei berücksichtigen einerseits die Prüf lose 1 und 2 mit den im Transportbetonwerk hergestellten Betonzylindern die Erst-/Eignungsprüfung und das darauf aufbauende Prüflos 3 mit Bohrkernen aus einer im Feldversuch hergestellten Fahrbahnplatte mit gleicher Betonrezeptur die Übereinstimmungskontrolle bei Neubaumaßnahmen. Andererseits findet der Einsatz des Prüfverfahrens bei der Restsubstanzbewertung von Betonfahrbahnplatten bei den Prüflosen 4 bis 7 mit den Bohrkernen aus vier in Waschbetonbauweise ausgeführten Fahrbahnplatten Berücksichtigung. Das zusätzlich aufgenommene Prüflos 8 mit einem Labormörtel dient der Herausarbeitung des Materialeinflusses auf die Präzision der Spaltzugfestigkeitsprüfung. Zusammenfassend kann festgestellt werden, dass die Präzision der in der AL SP-Beton beschriebenen Spaltzugfestigkeitsprüfung mit einem Variationskoeffizienten von weniger als 10 % unter Wiederhol- und Vergleichbedingungen hinreichend genau ist. Der geringe Unterschied zwischen den Variationskoeffizienten unter Wiederhol- und Vergleichbedingungen lässt zusätzlich den Schluss zu, dass der Einfluss des unterschiedlichen Personals und der verschiedenartigen Prüftechniken bei den einzelnen Prüfstellen relativ gering ist. Die im Rahmen des Ringversuchs gewonnenen Erkenntnisse haben bereits partiell Eingang in die Normung gefunden. T2 - Betonstraßentagung 2013 CY - Karlsruhe, Germany DA - 19.09.2013 KW - Spaltzugfestigkeit KW - Ringversuch KW - Präzision KW - Vergleich- und Wiederholbedingungen PY - 2013 SN - 978-3-86446-076-0 N1 - Serientitel: FGSV-Schriftenreihe der Arbeitsgruppe Betonbauweisen – Series title: FGSV-Schriftenreihe der Arbeitsgruppe Betonbauweisen SP - 106 EP - 122 AN - OPUS4-30622 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Weise, Frank A1 - Patitz, G. A1 - Redmer, B. A1 - Hübner, M. T1 - Zerstörungsfreie Strukturaufklärung antiker Baudenkmäler des Pergamonmuseums N2 - Das Pergamonmuseum ist eines der am meisten besuchten Museen Berlins. Es wird seit etwa 20 Jahren im Rahmen des 1999 von der Stiftung Preußischer Kulturbesitz beschlossenen Masterplans Museumsinsel schrittweise grundhaft instandgesetzt und um einen weiteren Flügel ergänzt, der 2025 fertig gestellt sein soll. In diesem Kontext wurde auch kurz nach dem Beschluss des Masterplans eine Bauzustandsanalyse an den in Originalgröße in der Antikensammlung ausgestellten Baudenk¬ mälern durchgeführt. Allerdings stellte man dabei fest, dass herkömmliche Erkundungsverfahren wie die Bauaufnahme, die baugeschichtliche Untersu¬ chung, das Quellenstudium sowie die äußerliche Begutachtung nicht ausreichen, um die innere Struktur der antiken Baudenkmäler hinreichend zu charakterisieren. Deshalb wurde die BAM im Jahr 2003 von der ARGE Pfanner Pergamonmuseum beauftragt, in enger Zusammenarbeit mit zwei Ingenieurbüros, dem Ingenieurbüro Patitz (IGP) und der Gesellschaft für geophysikalische Unter¬ suchungen mbH (GGU) unter Hinzuziehung einer Restauratorin, die innere Struktur ausgewählter an¬ tiker Baudenkmäler zerstörungsfrei zu untersuchen. Das Ziel der zerstörungsfreien Strukturaufklärung zum inneren Aufbau der Bauteile war es, einerseits sicherheitsrelevante Informationen für die statische Nachweisführung bereitzustellen, sowie andererseits eine Planungsgrundlage für die eventuell erforder¬ liche Ertüchtigung der Baudenkmäler zu schaffen. Im Fokus der Untersuchungen standen dabei das Markttor von Milet und das Säulenjoch der Heiligen Halle am Markt von Priene1 • Im nachstehenden Beitrag werden exemplarisch die am Markttor von Milet durchgeführten Untersuchungen vorgestellt. T2 - Workshop Kulturguterhaltung - Vom Dampfkessel zu Nanomaterialien CY - Berlin, Germany DA - 17.11.2021 KW - Bauzustandsanalyse KW - Radar KW - Radiografie PY - 2021 SN - 2567-1251 VL - 3 SP - 47 EP - 57 PB - Druckerei G. Bohm CY - Berlin AN - OPUS4-54460 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Weise, Frank A1 - Fladt, Matthias A1 - Wieland, M. T1 - Internal water-repellent treatment - a novel strategy for mitigating alkali-aggregate reaction in concrete pavements N2 - To prevent future alkali-aggregate reaction (AAR) damage, which has occurred frequently in the Germanhighway network in recent years, a new regulation has been drafted. This regulation severely limits the use of alkali-sensitive aggregates by requiring that their suitability be verified by certified inspectors using newly developed AAR concrete tests that involve the external supply of alkali. This has led to a significant limitation in the number of aggregates usable for concrete pavements. A novel AAR avoidance strategy is now being pursued, which aims to enable the use of borderline alkali-sensitive aggregates through the application of an internal water-repellent treatment. The addition of water repellents during concrete production should significantly reduce the ingress of water and external de-icing salts into the concrete pavement, thus reducing the potential for AAR damage. This paper presents the results of laboratory tests to assess the suitability of this new AAR prevention strategy. Representative, highly AAR-susceptible road paving concrete made with an alkali- sensitive greywacke and various water repellents were used as the basis for these experiments. The tests for concrete suitability included determining the conventional fresh and hardened concrete properties as well as concrete prism tests with external alkaline supply. Building on these results, laser-induced breakdown spectroscopy (LIBS) analyses of de-icing-salt intrusion as well as microscopic examinations for verification of the AAR characteristics were carried out. The results of the AAR concrete tests with external alkaline supply support the conclusion that, when hydrophobic agents containing a suitable active ingredient are used, the AAR damage process in road paving concrete can be sufficiently prevented. T2 - 16th International Conference on Alkali-Aggregate Reaction in Concrete CY - Lisboa, Portugal DA - 31.05.2022 KW - Concrete pavements KW - Internal water-repellent treatment KW - Preventive measures KW - Testing for potential AAR PY - 2021 SN - 978-972-49-2315-4 VL - 1 SP - 511 EP - 524 AN - OPUS4-54551 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Kositz, M. A1 - Hünger, K.-J. A1 - Weise, Frank T1 - Regression analysis of ASR expansions and silica dissolution in the presence of NaCl N2 - The durability of concrete structures due to alkali-silica-reaction (ASR) is usually been assessed by ASR concrete prism tests (CPT). Therefore, the expansion of concrete specimens indicates an alkalisensitivity. In Germany these tests are performed at 40°C or accelerated 60°C. Nevertheless, ASR prism tests are expensive, power and time-consuming. For these reasons, an alternative chemical test (“mod. BTU-test”) was developed in the past. The “mod. BTU-test” was correlated with German standard CPT. In this test, the solubility of silica and alumina in the liquid phase is measured by ICP-OES. For special requirements in concrete road construction, stricter test procedures are necessary. The specimens are repeatedly subjected to cyclic alternating storage in NaCl. On the one hand, the presence of NaCl increases the ASR expansion, on the other hand NaCl also changes the dissolution behaviour of silica and alumina. For now is not possible to correlate the solubilities of “mod. BTU-test” and ASR expansions influenced by NaCl. Therefore, four aggregates with different ASR sensitivities were chosen and ASR concrete prism tests (in addition with NaCl) have been performed. According to the “mod. BTU-test” the solubilities of silica and alumina in presence of different NaCl concentrations were measured. This paper is about the regression analysis of silica and alumina dissolution and ASR expansion tests in presence of NaCl. The regression analysis shows the influence of a quasi-continuous and an interrupted cyclic alternating storage. Additionally the effects of temperature and NaCl concentration are investigated. In the end, a suitable NaCl concentration of the “mod. BTU-test” for dissolution experiments is recommended. The “mod. BTU-Test” with NaCl might be a serious and reliable test method for ASR classification for concrete road construction. T2 - 16th International Conference on Alkali-Aggregate Reaction in Concrete CY - Lisboa, Portugal DA - 31.05.2022 KW - Alkali silica reaction KW - Alkaline solution KW - Alumina & silica dissolution KW - NaCl KW - Regression analysis PY - 2021 SN - 978-972-49-2315-4 VL - 1 SP - 711 EP - 723 AN - OPUS4-54552 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Schilder, Constanze A1 - Kohlhoff, Harald A1 - Hofmann, Detlef A1 - Basedau, Frank A1 - Habel, Wolfgang A1 - Baeßler, Matthias A1 - Niederleithinger, Ernst A1 - Georgi, Steven A1 - Herten, M. ED - Jaroszewicz, L.R. T1 - Static and dynamic pile testing of reinforced concrete piles with structure integrated fibre optic strain sensors N2 - Static and dynamic pile tests are carried out to determine the load bearing capacity and the quality of reinforced concrete piles. As part of a round robin test to evaluate dynamic load tests, structure integrated fibre optic strain sensors were used to receive more detailed information about the strains along the pile length compared to conventional measurements at the pile head. This paper shows the instrumentation of the pile with extrinsic Fabry-Perot interferometers sensors and fibre Bragg gratings sensors together with the results of the conducted static load test as well as the dynamic load Tests and pile integrity tests. T2 - EWOFS 2013 - 5th European workshop on optical fibre sensors CY - Kraków, Poland DA - 19.05.2013 KW - Static load test KW - Dynamic load test KW - Pile integrity test KW - Extrinsic Fabry-Perot interferometer KW - Fibre Bragg grating KW - Structure integrated sensor KW - Fibre optic strain sensor PY - 2013 SN - 978-0-81949-634-8 DO - https://doi.org/10.1117/12.2026813 SN - 0277-786X N1 - Serientitel: Proceedings of SPIE – Series title: Proceedings of SPIE VL - 8794 IS - Paper 8794 - 181 SP - 700 EP - 703 AN - OPUS4-28854 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Niederleithinger, Ernst A1 - Gardner, S. A1 - Kind, Thomas A1 - Kaiser, R. A1 - Grunwald, Marcel A1 - Yang, G. A1 - Redmer, Bernhard A1 - Waske, Anja A1 - Mielentz, Frank A1 - Effner, Ute A1 - Köpp, Christian A1 - Clarkson, A. A1 - Thompson, F. A1 - Ryan, M. A1 - Mahon, D. T1 - Muon Tomography of the Interior of a Reinforced Concrete Block: First Experimental Proof of Concept N2 - Quality assurance and condition assessment of concrete structures is an important topic world-wide due to the aging infrastructure and increasing traffic demands. Common topics include, but are not limited to, localisation of rebar or tendon ducts, geometrical irregularities, cracks, voids, honeycombing or other flaws. Non-destructive techniques such as ultrasound or radar have found regular, successful practical application but sometimes suffer from limited resolution and accuracy, imaging artefacts or restrictions in detecting certain features. Until the 1980s X-ray transmission was used in case of special demands and showed a much better resolution than other NDT techniques. However, due to safety concerns and cost issues, this method is almost never used anymore. Muon tomography has received much attention recently. Novel detectors for cosmic muons and tomographic imaging algorithms have opened up new fields of application, such as the investigation of freight containers. Muon imaging also has the potential to fill some of the gaps currently existing in concrete NDT. As a first step towards practical use and as a proof of concept we used an existing system to image the interior of a reference reinforced 600 kg concrete block. Even with a yet not optimized setup for this kind of investigation, the muon imaging results are at least of similar quality compared to ultrasonic and radar imaging, potentially even better. The data acquisition takes more time and signals contain more noise, but the images allowed to detect the same important features that are visible in conventional high energy X-ray tomography. In our experiment, we have shown that muon imaging has potential for concrete inspection. The next steps include the development of mobile detectors and optimising acquisition and imaging parameters. KW - Concrete KW - Muon KW - Radar KW - Ultrasound KW - X-ray PY - 2021 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-529974 DO - https://doi.org/10.1007/s10921-021-00797-3 VL - 40 IS - 3 SP - 1 EP - 14 PB - Springer Nature AN - OPUS4-52997 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Weise, Frank A1 - Hüsken, Götz A1 - Niedack-Nad, Marianne A1 - Wieland, M. T1 - AL Sp-Beton - Präzision des Prüfverfahrens N2 - Für die rechnerische Dimensionierung der Betondecken im Oberbau von Verkehrsflächen für den Neubau sowie die Erneuerung nach RDO-Beton 09 ist die statische Spaltzugfestigkeit an der unteren bzw. unteren und oberen Scheibe des Betonzylinders bzw. Bohrkerns entsprechend der Vorgaben der AL Sp-Beton zu bestimmen. Aufgrund der unzureichenden Kenntnis der Präzision dieses Prüfverfahrens wurden mit einem breit aufgestellten Ringversuch die statistischen Kennwerte an Labor- und Bestandsbetonen unter Vergleich- und Wiederholbedingungen auf der Grundlage des FGSV-Merkblatts über die statistische Auswertung von Prüfergebnissen ermittelt. Für eine möglichst gute statistische Absicherung nahmen an dem Ringversuch dreizehn erfahrene Prüfstellen teil. Zur Abdeckung des vielschichtigen Einsatzes des Prüfverfahrens erfolgte der Ringversuch an acht Prüflosen. Dabei berücksichtigen einerseits die Prüflose 1 und 2 mit den im Transportbetonwerk hergestellten Betonzylindern die Erst-/Eignungsprüfung und das darauf aufbauende Prüflos 3 mit Bohrkernen aus einer im Feldversuch hergestellten Fahrbahnplatte mit gleicher Betonrezeptur die Übereinstimmungskontrolle bei Neubaumaßnahmen. Andererseits findet der Einsatz des Prüfverfahrens bei der Restsubstanzbewertung von Betonfahrbahnplatten bei den Prüflosen 4 bis 7 mit den Bohrkernen aus vier in Waschbetonbauweise ausgeführten Fahrbahnplatten Berücksichtigung. Das zusätzlich aufgenommene Prüflos 8 mit einem Labormörtel dient der Herausarbeitung des Materialeinflusses auf die Präzision der Spaltzugfestigkeitsprüfung. Zusammenfassend kann festgestellt werden, dass die Präzision der in der AL SP-Beton beschriebenen Spaltzugfestigkeitsprüfung mit einem Variationskoeffizienten von weniger als 10 % unter Wiederhol- und Vergleichsbedingungen hinreichend genau ist. Der geringe Unterschied zwischen den Variationskoeffizienten unter Wiederhol- und Vergleichsbedingungen lässt zusätzlich den Schluss zu, dass der Einfluss des unterschiedlichen Personals und der verschiedenartigen Prüftechniken bei den einzelnen Prüfstellen relativ gering ist. Die im Rahmen des Ringversuchs gewonnenen Erkenntnisse haben bereits partiell Eingang in die Normung gefunden. KW - Betonfahrbahndecken KW - Spaltzugfestigkeit KW - Ringversuch KW - Verfahrenspräzision PY - 2014 SN - 0039-2162 VL - 66 IS - 10 SP - 790 EP - 798 PB - Kirschbaum-Verl. CY - Bonn-Bad Godesberg AN - OPUS4-32066 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Weise, Frank A1 - Redmer, Bernhard A1 - Müller, Urs A1 - Hübner, M. T1 - Condition assessment of ancient architectural monuments in the Pergamon museum - The combined application of NDT-methods for structural investigations KW - ZFP PY - 2008 SN - 0344-5089 VL - 21 SP - 23 EP - 32 PB - Staatliche Museen CY - Berlin AN - OPUS4-18585 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Weise, Frank A1 - Redmer, Bernhard A1 - Hübner, M. ED - Forde, M. T1 - Combination of non-destructive testing methods for structural investigations of ancient architectural monuments T2 - 11th International Conference and Exhibiton "Structural Faults and Repair - 2006" CY - Edinburgh, Scotland, UK DA - 2006-06-13 KW - Ancient Monuments KW - Reinforcement Detection KW - Radar KW - Videoscopy KW - Stereoradiography PY - 2006 SN - 0-947644-59-8 SP - 1 EP - 9 PB - Engineering Technics Pr., CY - Edingburgh AN - OPUS4-14401 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Rai, Alena A1 - Stelzner, Ludwig A1 - Weise, Frank A1 - Wieland, M. T1 - 3D-Analyse von Betonfahrbahnoberflächen mit Grinding- und Groovingtextur mittels Streifenlichtprojektion N2 - Die Oberflächentexturierung der Betonfahrbahndecken mittels Grinding- und Grooving steht seit einigen Jahren im Mittelpunkt der Forschung und Entwicklung des Betonstraßenbaus in Deutschland. In den vergangenen Jahren wurden die vorteilhaften Oberflächenperformances derartiger Texturen wie z.B. Griffigkeit, Ebenheit, Lärmminderung in zahlreichen Forschungsprojekten umfassend untersucht und daraus die Technologie „Texturgrinding“ entwickelt. Im Kontext des gegenwärtig verfolgten ganzheitlichen performanceorientierten Ansatzes liegt der Fokus nun verstärkt auf der Analyse und Charakterisierung der Oberflächentopografie von Grinding- bzw. Groovingtexturen. Insbesondere gilt ein Hauptaugenmerk hierbei der zeitlichen Entwicklung der Oberflächentexturen in Abhängigkeit von äußeren Einwirkungen durch Klima und Verkehr. Dieser Beitrag zeigt, dass durch den Einsatz eines auf Streifenlichtprojektion basierenden Messsystems, eine hochaufgelöste dreidimensionale Erfassung der Oberflächentopografie verschiedenartiger Grinding- und Groovingtexturen möglich ist. Darauf aufbauend wurden messtechnische Voraussetzungen zur Gewährleistung reproduzierbarer Messungen geschaffen, die eine Dokumentation der zeitlichen Texturveränderungen infolge klimatischer Beanspruchung ermöglichen. Anschließend wurden Auswerteroutinen zur quantitativen und statistischen Charakterisierung der Oberflächentextur entwickelt und angewandt, um exemplarisch die Veränderungen der Oberflächentopografie infolge klimatischer Beanspruchung quantitativ abzubilden. KW - Betonfahrbahndecken KW - Grinding KW - Grooving KW - Oberflächentexturierung KW - Streifenlichtprojektion PY - 2020 DO - https://doi.org/10.1002/best.202000015 SP - 1 EP - 9 PB - Wilhelm Ernst & Sohn Verlag für Architektur und technische Wissenschaften GmbH & Co. KG CY - Berlin AN - OPUS4-51012 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Weise, Frank A1 - Maier, Bärbel A1 - Alonso, M. T. A1 - Müller, C. T1 - Analyse des Verhaltens von Gesteinskörnungen im Beton bei Frosttauwechselbeanspruchung N2 - Die hier vorgestellten Untersuchungen erfolgten im Rahmen eines von der AiF geförderten Verbundforschungsvorhabens „Frost- und Frost-Tausalz-Widerstand von Beton unter besonderer Berücksichtigung der verwendeten Gesteinskörnung“. Sie waren insbesondere Bestandteil des gemeinsam vom VDZ und der BAM bearbeiteten Teilprojektes „Prüfung der Gesteinskörnung im Beton“, Die Basis für die Auswahl der zu untersuchenden Gesteinskörnungen bildeten die Teilprojekte der Bauhaus Universität Weimar zur Petrographie sowie der TU München zum Frost- und Frost-Tausalz-Widerstand der Gesteinskörnung, Ausgangspunkt des Vorhabens war die Feststellung, dass die Beurteilung des Frost und Frost-Tausalz-Widerstandes von Gesteinskörnungen mit Laborprüfverfahren an der Gesteinskörnung und im Beton, je nach verwendetem Prüfverfahren und Grenzwerten, zu einer unterschiedlichen Klassifizierung führen kann, Bisher kann bei keiner Form der Prüfung des Frost- bzw. Frost-Tausalz-Widerstandes an der Gesteinskörnung ausgeschlossen werden, dass die Gesteinskörnung in dieser Prüfung ein anderes Verhalten aufweist, als später im Bauwerk im einbetonierten Zustand. In diesem Beitrag wird ausschließlich das Frostverhalten ausgewählter Gesteinskörnungen in XF3-Betonen unter Verwendung eines Portlandzements CEM I 32,5 R dargestellt. Es werden betontechnologische Maßnahmen zur Verbesserung des Frostverhaltens eines Betons, der mit einer nicht frostbeständigen Gesteinskörnung hergestellt wurde, aufgezeigt. Zur Verfolgung der inneren frostinduzierten Gefügeveränderung kamen neben konventionellen Prüftechniken auch erstmals röntgentomografische Untersuchungen zum Einsatz. T2 - 18. Ibausil - Internationale Baustofftagung CY - Weimar, Germany DA - 12.09.2012 PY - 2012 SN - 978-3-00-034075-8 VL - 2 IS - 3.07 SP - 2-0453 EP - 2-0467 AN - OPUS4-26546 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Hurtado-Hurtado, G. A1 - Morales-Velazquez, L. A1 - Valtierra-Rodríguez, M. A1 - Otremba, Frank A1 - Jáuregui-Correa, J. C. T1 - Frequency Analysis of the Railway Track under Loads Caused by the Hunting Phenomenon N2 - Hunting is a potentially dangerous phenomenon related to the lateral oscillation of the wheels that impacts the rails and causes the wear of the infrastructure’s components. Therefore, the analysis and timely detection of hunting can lead to the application of corrective maintenance tasks, reducing damages, and costs and even derailments as a result. In this work, the vibration response of a finite element model of a rail with hunting-induced loads by a single wheel is analyzed in three directions: longitudinal, lateral, and vertical. The contact patch forces are calculated by means of Simpack® using the Kalker linear theory and the contact Hertz theory. The system is solved by using the Newmark-_ approach. The results of the deflection and vibration analysis, following the proposed methodology, show how the different characteristics of the loads impact the rail. KW - Continuous wavelet transform KW - Empirical mode decomposition KW - Finite element method KW - Frequency analysis KW - Hunting phenomenon KW - Mechanical modelling KW - Rail vibrations PY - 2022 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-551517 UR - https://www.mdpi.com/2227-7390/10/13/2286/htm# DO - https://doi.org/10.3390/math10132286 VL - 10 IS - 13 SP - 1 EP - 17 PB - MDPI AN - OPUS4-55151 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Romero-Navarrete, José A. A1 - Otremba, Frank A1 - Sklorz, Christian A1 - Martínez Madrid, M. T1 - Quasistatic rollover threshold of atmospheric road tankers N2 - Several geometrical analytical tools can be used for assessing the potential benefits of any alternative tank shape. The quasistatic evaluation of the cargo-vehicle behavior represents a fast way to objectively determine the roll stability benefits of any potentially new tank shape. In this paper, the geometrical, quasistatic rollover performance of a convex bottom tank shape is compared with that of standard tank shapes, finding that in spite of the lower position of the cargo´s center of gravity in such a tank shape for the un-perturbed condition, it has the same performance as the elliptical tank shape when subjected to Steady lateral acceleration. That as a result of the large cargo´s lateral displacement. Consequently, the combination of a lower center of gravity for the cargo when it is not perturbed, and a Minimum lateral shift due to lateral accelerations inputs, define the conditions for an ideal tank shape. T2 - CONIIN 2020 CY - Online meeting DA - 28.09.2020 KW - Tank shape KW - Road tankers KW - Center of gravity shifting KW - Quasistatic KW - Convex bottom KW - Geometrical analysis PY - 2020 SP - 1 EP - 6 AN - OPUS4-51388 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Bradley, Ian A1 - Scarponi, G. E. A1 - Otremba, Frank A1 - Birk, A. M. T1 - An overview of test standards and regulations relevant to the fire testing of pressure vessels N2 - Fire exposure of storage and transportation vessels of hazardous materials (including pressure liquefied gases) can result in BLEVEs and other high-consequence incidents with large societal and economic impacts. To reduce risk most countries have numerous regulations, codes of practice and guidance notes covering the design, operation and maintenance of vessels and thermal protection systems. Yet despite such regulations there remains no internationally accepted fire test procedure for pressure vessel and accompanying thermal protection systems that is capable of meeting a range of regulatory requirements. This paper considers some of the regulations in place in the western world and considers the origin of these based on large and medium-scale testing conducted to date. It examines conditions found in these tests to propose a set of recommendations on which to base a standard method of test. These recommendations are proposed as being representative of a credible large pool fire scenario that may occur. KW - LPG KW - Pressure vessel KW - Test KW - BLEVE KW - Fire PY - 2021 DO - https://doi.org/10.1016/j.psep.2020.07.047 SN - 0957-5820 VL - 145 SP - 150 EP - 156 PB - Elsevier CY - Amsterdam AN - OPUS4-51139 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Adamus, A. A1 - Ali, I. A1 - Vasileiadis, V. A1 - Al-Hileh, L. A1 - Lisec, Jan A1 - Frank, M. A1 - Seitz, G. A1 - Engel, N. T1 - Vincetoxicum arnottianum modulates motility features and metastatic marker expression in pediatric rhabdomyosarcoma by stabilizing the actin cytoskeleton N2 - Background: Prevention of metastatic invasion is one of the main challenges in the treatment of alveolar rhabdomyosarcoma. Still the therapeutic options are limited. Therefore, an anti-tumor screening was initiated focusing on the anti-metastatic and anti-invasion properties of selected medicinal plant extracts and phytoestrogens, already known to be effective in the prevention and treatment of different cancer entities. Methods: Treatment effects were first evaluated by cell viability, migration, invasion, and colony forming assays on the alveolar rhabdomyosarcoma cell line RH-30 in comparison with healthy primary cells. Results: Initial anti-tumor screenings of all substances analyzed in this study, identified the plant extract of Vincetoxicum arnottianum (VSM) as the most promising candidate, harboring the highest anti-metastatic potential. Those significant anti-motility properties were proven by a reduced ability for migration (60%), invasion (99%) and colony formation (61%) under 48 h exposure to 25 μg/ml VSM. The restricted motility features were due to an induction of the stabilization of the cytoskeleton – actin fibers were 2.5-fold longer and were spanning the entire cell. Decreased proliferation (PCNA, AMT, GCSH) and altered metastasis (e. g. SGPL1, CXCR4, stathmin) marker expression on transcript and protein level confirmed the significant lowered tumorigenicity under VSM treatment. Finally, significant alterations in the cell metabolism were detected for 25 metabolites, with levels of uracil, N-acetyl serine and propanoyl phosphate harboring the greatest alterations. Compared to the conventional therapy with cisplatin, VSM treated cells demonstrated a similar metabolic shutdown of the primary cell metabolism. Primary control cells were not affected by the VSM treatment. Conclusions: This study revealed the VSM root extract as a potential, new migrastatic drug candidate for the putative treatment of pediatric alveolar rhabdomyosarcoma with actin filament stabilizing properties and accompanied by a marginal effect on the vitality of primary cells. KW - Mass Spectroscopy KW - Metabolomics KW - Cancer PY - 2021 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-533530 DO - https://doi.org/10.1186/s12906-021-03299-x VL - 21 IS - 1 PB - Springer Nature AN - OPUS4-53353 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Adamus, A. A1 - Peer, K. A1 - Ali, I. A1 - Lisec, Jan A1 - Falodun, A. A1 - Frank, M. A1 - Seitz, G. A1 - Engel, N. T1 - Berberis orthobotrys – A promising herbal anti-tumorigenic candidate for the treatment of pediatric alveolar rhabdomyosarcoma N2 - Ethnopharmacological relevance: Berberis orthobotrys (BORM) is a medical plant with a long history in traditional usage for the treatment of wounds, cancer, gastrointestinal malady and several other diseases. Our previous studies identified the endemic Pakistani plant Berberis orthobotrys Bien. ex Aitch. as promising source for the treatment of breast cancer and osteosarcoma. Aim of the study: The present study was aimed to evaluate the anti-cancer properties of 26 plant derived extracts and compounds including the methanolic root extract of Berberis orthobotrys (BORM) on pediatric alveolar rhabdomyosarcoma (RMA), which is known to develop drug resistance, metastatic invasion and potential Tumor progression. Materials and methods: The main anti-tumor activity of BORM was verified by focusing on morphological, cell structural and metabolic alterations via metabolic profiling, cell viability measurements, flow cytometry, western blotting and diverse microscopy-based methods using the human RMA cell line Rh30. Results: Exposure of 25 μg/ml BORM exerts an influence on the cell stability, the degradation of oncosomes as well as the shutdown of the metabolic activity of RMA cells, primarily by downregulation of the energy metabolism. Therefore glycyl-aspartic acid and N-acetyl serine decreased moderately, and uracil increased intracellularly. On healthy, non-transformed muscle cells BORM revealed very low metabolic alterations and nearly no cytotoxic impact. Furthermore, BORM is also capable to reduce Rh30 cell migration (~50%) and proliferation (induced G2/M cycle arrest) as well as to initiate apoptosis confirmed by reduced Bcl-2, Bax and PCNA expression and induced PARP-1 cleavage. Conclusions: The study provides the first evidence, that BORM treatment is effective against RMA cells with low side effects on healthy cells. KW - Mass-Spectrometry PY - 2018 DO - https://doi.org/10.1016/j.jep.2018.10.002 SN - 0378-8741 VL - 229 SP - 262 EP - 271 PB - Elsevier B.V. AN - OPUS4-46458 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gant, Simon A1 - Chang, Joseph A1 - Hetherington, Rory A1 - Hanna, Steven A1 - Tickle, Gemma A1 - Spicer, Tom A1 - McMasters, Sun A1 - Fox, Shannon A1 - Meris, Ron A1 - Bradley, Scott A1 - Miner, Sean A1 - King, Matthew A1 - Simpson, Steven A1 - Mazzola, Thomas A1 - McGillivray, Alison A1 - Tucker, Harvey A1 - Björnham, Oscar A1 - Carissimo, Bertrand A1 - Fabbri, Luciano A1 - Wood, Maureen A1 - Habib, Abdel Karim A1 - Harper, Mike A1 - Hart, Frank A1 - Vik, Thomas A1 - Helgeland, Anders A1 - Howard, Joel A1 - Mauri, Lorenzo A1 - Mackie, Shona A1 - Mack, Andreas A1 - Lacome, Jean-Marc A1 - Puttick, Stephen A1 - Ibrahim, Adeel A1 - Miller, Derek A1 - Dharmavaram, Seshu A1 - Shen, Amy A1 - Cunningham, Alyssa A1 - Beverly, Desiree A1 - O’Neal, Daniel M. A1 - Verdier, Laurent A1 - Burkhart, Stéphane A1 - Dixon, Chris A1 - Nilsen, Sandra A1 - Bradley, Robert A1 - Skarsvåg, Hans L. A1 - Fyhn, Eirik H. A1 - Aasen, Ailo T1 - Pressure-Liquefied Ammonia Jet Dispersion: Multi-Model Intercomparison Using Desert Tortoise and FLADIS Field Data N2 - This paper presents the findings of an international model inter-comparison exercise that was undertaken in the period 2021-2024 to assess the performance of atmospheric dispersion models for simulating releases of pressure-liquefied ammonia. The exercise used data from ammonia field trials dating from the 1980s and 1990s: the Desert Tortoise and the FLADIS trials. Concentration data from two arcs of sensors in the Desert Tortoise trials and three arcs of sensors in the FLADIS trials were used. Twenty-one independent modelling teams from North America and Europe participated in the exercise and provided in total twenty-seven sets of results from a range of different models, including empirically-based nomograms, integral, Gaussian puff, Lagrangian particle, and Computational Fluid Dynamics (CFD) models. The work is novel in presenting the results from such a large cohort of models, examining specifically the dispersion behaviour of ammonia. This is particularly relevant at the current time, given the growing international interest in using ammonia as a clean energy vector and shipping fuel. The study found that the agreement between model predictions and measurements (as determined by performance measures such as geometric mean bias and geometric variance) varied between different models. At any downwind distance, the range in predicted plume arc-max concentrations spanned a range of up to one or two orders of magnitude about the measurements. Several modelling teams used the same models and, in most cases, their predictions differed. Given appropriate inputs, most models generally predicted concentrations that agreed with the data within commonly-used model acceptance criteria. There was no single class of model that provided superior predictions to others; predictions from several empirically-based nomograms, integral, Gaussian puff, Lagrangian particle, and CFD models were all in close agreement with the data (as defined by the model acceptance criteria). The findings of the exercise are being used to help plan a programme of future ammonia experiments in the USA, called the Jack Rabbit III trials. The results are also useful for assessing the performance of models that may be applied to assess risks at ammonia facilities, and for emergency planning and response. KW - Ammonia KW - Atmospheric dispersion KW - Validation KW - Jack rabbit PY - 2025 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-646069 DO - https://doi.org/10.1016/j.aeaoa.2025.100389 SN - 2590-1621 VL - 28 SP - 1 EP - 76 PB - Elsevier Ltd. AN - OPUS4-64606 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Ferrero, Fabio A1 - Kluge, Martin A1 - Schmidtchen, Ulrich A1 - Pahl, Robert A1 - Noack, Jennifer A1 - Kolvitz, Kristian A1 - Runge, Thomas A1 - Holtappels, Kai A1 - Hensel, Christina A1 - Bönig, Jürgen A1 - Schulze, Uwe A1 - Askar, Enis A1 - Frank, M. A1 - Thornton, D. T1 - Experimentelle und numerische Untersuchungen des Verhaltens von Acetylenflaschen im Feuer T2 - 12. Kolloquium zu Fragen der chemischen und physikalischen Sicherheitstechnik CY - Berlin, Deutschland DA - 2010-06-15 KW - Acetylendruckgasbehälter KW - Unterfeuerung KW - Aufheizverhalten KW - CFD-Modellierung PY - 2010 SN - 978-3-9813550-1-7 SN - 0938-5533 N1 - Geburtsname von Kluge, Martin: Beckmann-Kluge, M. - Birth name of Kluge, Martin: Beckmann-Kluge, M. SP - 70 EP - 72 PB - BAM Bundesanstalt für Materialforschung und -prüfung CY - Berlin AN - OPUS4-21488 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wille, Frank A1 - Ballheimer, Viktor A1 - Apel, Andreas A1 - Kuschke, Christian A1 - Moutarde, M. A1 - Desnoyers, B. A1 - Kalinina, E. A1 - Ammerman, D. T1 - ISO-Standard and IAEA guidance material for package load attachment Points - Current approaches and developments N2 - For transport package design and operation according to the IAEA regulations, the package shall be securely stowed and its retention system shall be capable to withstand load conditions of routine transport. The supporting IAEA Advisory Material SSG-26 provides information how to do that. Up to now package designers in different countries use other load factors for the design of attachment points than those specified in the IAEA guidance material. In particular the acceleration values vary between different countries and lead to difficulties during the validation of foreign approval certificates. Therefore the IAEA started a discussion process to review the existing guidance text. An international working group was constituted in 2013. Representatives came from different stakeholders, e.g. transport operators, competent authorities and modal organizations. The discussions concluded especially on the transport conditions which has to be considered for stowage design, including on the one hand the relevance of the load factors used for strength and fatigue analysis and on the other hand the criteria which have to be considered for the attachment points. The proposed acceleration values will be compared to those measured during recent multi-modal testing by Sandia National Laboratories that measured the acceleration levels experienced by a spent fuel flask during heavy-haul truck, sea, and rail transport. The ISO standard 10276 is dealing with the load attachment systems of packages as well. This standard considers the trunnion design, manufacturing and operational aspects. The regular standard revision phase started in 2017. An expert group discussed new state-of-the-art technology, different analysis approaches for strength and fatigue analysis and proposed revised text for the ISO standard for international discussion. The finite-element analysis approach incl. appropriate acceptance criteria are described and referenced. The paper describes relevant tie-down aspects, gives background argumentation relevant to analysis approaches, and tries to support harmonized application of the revised IAEA guidance material and the future revised ISO standard. T2 - 19th International Symposium on the Packaging and Transportation of Radioactive Materials PATRAM 2019 CY - New Orleans, LA, USA DA - 04.08.2019 KW - Load attachment KW - Stowage KW - Trunnion KW - Bolt design KW - Retention KW - Acceleration KW - Transport KW - Load cycles PY - 2019 SP - Paper 1130, 1 EP - 10 AN - OPUS4-49095 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wille, Frank A1 - Debruyne, M. A1 - Eckert, B. A1 - Gauthier, F. A1 - Ben Ouaghrem, K. A1 - Le Bars, I. A1 - Jouve, A.-C. A1 - Cordier, N. T1 - Assessment of safety demonstrations relative to packages containing UF6 N2 - The safety demonstrations realized by applicants in the case of approval request for the package designs containing enriched UF6 have to take into account some specific technical issues. Concerning the shipment of enriched UF6, the package designs consist in general of a filled 30B cylinder surrounded by an overpack. The description of the content, considering the UF6 origin, i.e. natural or reprocessed, shall be clearly justified especially when the UF6 isotopic composition exceeds the limits specified in ASTM standards. Concerning the containment of the UF6, the applicant shall demonstrate in all conditions of transport the leak-tightness of the valve and plug of the cylinders filled with enriched UF6. In this regard, when mechanical justifications are based on numerical calculations, the absence of contact between these components of the cylinder and the internal surfaces of the overpack after the regulatory drop tests shall be shown to respect the IAEA regulations. Furthermore, the representativeness of the ballast used to simulate the behaviour of the UF6 loaded within the cylinder shall be justified if drop tests are performed. The representativeness of the ballast should also be justified for numerical calculations. In addition, the applicant shall demonstrate that the melting temperature of the valve and the plug, including the tinned joint, will not be exceeded during the regulatory fire test. Finally, specific provisions relative to the use of plugs and the maintenance of cylinders should be included in the safety analysis report. T2 - 19th International Symposium on the Packaging and Transportation of Radioactive Materials PATRAM 2019 CY - New Orleans, LA, USA DA - 04.08.2019 KW - Valve KW - Fire test KW - Content simulation KW - UF6 KW - Intumescent material PY - 2019 SP - Paper 1208, 1 EP - 8 AN - OPUS4-49094 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Schreiber, Frank A1 - Ackermann, M. T1 - Environmental drivers of metabolic heterogeneity in clonal microbial populations N2 - Microorganisms perform multiple metabolic functions that shape the global cycling of elements, health and disease of their host organisms, and biotechnological processes. The rates, at which different metabolic activities are performed by individual cells, can vary between genetically identical cells within clonal populations. While the molecular mechanisms that result in such metabolic heterogeneity have attracted considerable interest, the environmental conditions that shape heterogeneity and its consequences have received attention only in recent years. Here, we review the environmental drivers that lead to metabolic heterogeneity with a focus on nutrient limitation, temporal fluctuations and spatial structure, and the functional consequences of such heterogeneity. We highlight studies using single-cell methods that allow direct investigation of metabolic heterogeneity and discuss the relevance of metabolic heterogeneity in complex microbial communities. KW - Phenotypic variation KW - NanoSIMS KW - Diversity KW - Metabolism PY - 2019 UR - https://www.sciencedirect.com/science/article/abs/pii/S095816691930134X?via%3Dihub DO - https://doi.org/10.1016/j.copbio.2019.11.018 VL - 62 SP - 202 EP - 211 PB - Elsevier Ltd. AN - OPUS4-50194 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Helmerich, Rosemarie A1 - Mielentz, Frank A1 - Milmann, Boris A1 - Adam, Louisa A1 - Villalobos, S. A1 - Guimaraes, M. A1 - Wiggenhauser, Herbert T1 - Detection of cracks perpendicular to the surface using acoustic methods N2 - Cracks perpendicular to the surface may be initial indicators for a deterioration process of concrete structures. Moisture penetrates inside the structure and transports adverse chemicals. The paper presents an investigation about the reliability of available commercial non-destructive evaluation techniques to reliably estimate the depth of surface-breaking cracks in reinforced concrete structures. Aim of the study was the investigation of surface-braking cracks under laboratory conditions. Commercial acoustic devices as impact echo equipment, single ultrasonic transducers and arrays were applied even if they have not been developed for this purpose. The commercial software and descriptions for application was followed strictly to compare the function, precision and repeatability of the measurements. Both, perpendicular notches and cracks have been considered. The study was completed with a discussion about reference specimens. The study was the basis for formulation of gaps in research. The Electric Power Research Institute (EPRI) has initiated and funded a Project. T2 - NDT-CE 2015 - International symposium non-destructive testing in civil engineering CY - Berlin, Germany DA - 15.09.2015 KW - Acoustic test KW - Commercial acoustic devices KW - Ultrasonic test KW - Crack depth KW - Concrete specimens PY - 2015 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-345729 UR - https://www.ndt.net/?id=18412 SN - 1435-4934 VL - 20 IS - 11 SP - 1 EP - 9 PB - NDT.net CY - Kirchwald AN - OPUS4-34572 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Procop, Mathias A1 - Radtke, Martin A1 - Krumrey, M. A1 - Hasche, K. A1 - Schädlich, S. A1 - Frank, W. T1 - Electron probe microanalysis (EPMA) measurement of thin-film thickness in the nanometre range N2 - The thickness of thin films of platinum and nickel on fused silica and silicon substrates has been determined by EPMA using the commercial software STRATAGEM for calculation of film thickness. Film thickness ranged in the order 10 nm. An attempt was made to estimate the confidence range of the method by comparison with results from other methods of analysis. The data show that in addition to the uncertainty of the spectral intensity measurement and the complicated fitting routine, systematic deviation caused by the underlying model should be added. The scattering in the results from other methods does not enable specification of a range of uncertainty, but deviations from the real thickness are estimated to be less than 20%. KW - Electron probe microanalysis KW - EPMA KW - Thin films KW - Thickness measurement KW - X-rays PY - 2002 DO - https://doi.org/10.1007/s00216-002-1514-5 SN - 1618-2642 SN - 1618-2650 VL - 374 SP - 631 EP - 634 PB - Springer CY - Berlin AN - OPUS4-7090 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Varadarajan, A. A1 - Allan, R. A1 - Valentin, J. A1 - Castañeda Ocampo, O. A1 - Somerville, V. A1 - Buhmann, M. A1 - West, J. A1 - Skipp, Paul A1 - van der Mei, H. A1 - Ren, Q. A1 - Schreiber, Frank A1 - Webb, J. A1 - Pietsch, Franziska A1 - Ahrens, C. T1 - An integrated model system to gain mechanistic insights into biofilm-associated antimicrobial resistance in Pseudomonas aeruginosa MPAO1 N2 - Pseudomonas aeruginosa MPAO1 is the parental strain of the widely utilized transposon mutant collection for this important clinical pathogen. Here, we validate a model system to identify genes involved in biofilm growth and biofilm-associated antibiotic resistance. Our model employs a genomics-driven workflow to assemble the complete MPAO1 genome, identify unique and conserved genes by comparative genomics with the PAO1 reference strain and genes missed within existing assemblies by proteogenomics. Among over 200 unique MPAO1 genes, we identified six general essential genes that were overlooked when mapping public Tn-seq data sets against PAO1, including an antitoxin. Genomic data were integrated with phenotypic data from an experimental workflow using a user-friendly, soft lithography-based microfluidic flow chamber for biofilm growth and a screen with the Tn-mutant library in microtiter plates. The screen identified hitherto unknown genes involved in biofilm growth and antibiotic resistance. Experiments conducted with the flow chamber across three laboratories delivered reproducible data on P. aeruginosa biofilms and validated the function of both known genes and genes identified in the Tn-mutant screens. Differential Protein abundance data from planktonic cells versus biofilm confirmed the upregulation of candidates known to affect biofilm formation, of structural and secreted proteins of type VI secretion systems, and provided proteogenomic evidence for some missed MPAO1 genes. This integrated, broadly applicable model promises to improve the mechanistic understanding of biofilm formation, antimicrobial tolerance, and resistance evolution in biofilms. KW - Biofilms PY - 2020 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-515108 DO - https://doi.org/10.1038/s41522-020-00154-8 VL - 6 IS - 1 SP - Article number: 46 PB - Springer Nature CY - Singapore AN - OPUS4-51510 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Keshmiri, Hamid A1 - Armin, F. A1 - Elsayad, K. A1 - Schreiber, Frank A1 - Moreno, M. T1 - Leaky and waveguide modes in biperiodic holograms N2 - This study details a theoretical analysis of leaky and waveguide modes in biperiodic all-dielectric holograms. By tuning diffraction orders and subsequently confining local density of optical states at two distinct resonance wavelengths, we present a new class of highly sensitive refractive index biosensing platforms that are capable of resolving 35.5 to 41.3 nm/RIU of spectral shift for two separate biological analytes. KW - Antimicrobial resistance KW - Bacteria KW - Photonics KW - Diffractive gratings PY - 2021 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-527632 DO - https://doi.org/10.1038/s41598-021-89971-1 SN - 2045-2322 (online) VL - 11 IS - 1 SP - 10991 PB - Springer Nature AN - OPUS4-52763 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Pietsch, Franziska A1 - O'Neill, A. J. A1 - Ivask, A. A1 - Jenssen, H. A1 - Inkinen, J. A1 - Kahru, A. A1 - Ahonen, M. A1 - Schreiber, Frank T1 - Selection of resistance by antimicrobial coatings in the healthcare setting N2 - Antimicrobial touch surfaces have been introduced in healthcare settings with the aim of supporting existing hygiene procedures, and to help combat the increasing threat of antimicrobial resistance. However, concerns have been raised over the potential selection pressure exerted by such surfaces, which may drive the evolution and spread of antimicrobial resistance. This review highlights studies that indicate risks associated with resistance on antimicrobial surfaces by different processes, including evolution by de-novo mutation and horizontal gene transfer, and species sorting of inherently resistant bacteria dispersed on to antimicrobial surfaces. The review focuses on antimicrobial surfaces made of copper, silver and antimicrobial peptides because of the practical application of copper and silver, and the promising characteristics of antimicrobial peptides. The available data point to a potential for resistance selection and a subsequent increase in resistant strains via cross-resistance and co-resistance conferred by metal and antibiotic resistance traits. However, translational studies describing the development of resistance to antimicrobial touch surfaces in healthcare-related environments are rare, and will be needed to assess whether and how antimicrobial surfaces lead to resistance selection in These settings. Such studies will need to consider numerous variables, including the antimicrobial concentrations present in coatings, the occurrence of biofilms on surfaces, and the humidity relevant to dry-surface environments. On-site tests on the efficacy of antimicrobial Coatings should routinely evaluate the risk of selection associated with their use. KW - Antimicrobial resistance KW - Antimicrobial coating KW - Touch surfaces KW - Healthcare KW - Infections KW - COST action CA15114 AMICI PY - 2020 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-510926 DO - https://doi.org/10.1016/j.jhin.2020.06.006 SN - 0195-6701 VL - 106 IS - 1 SP - 115 EP - 125 PB - Elsevier Ltd AN - OPUS4-51092 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Braetz, S. A1 - Nordholt, Niclas A1 - Nerlich, A. A1 - Schreiber, Frank A1 - Tedin, K. A1 - Fulde, M. T1 - TisB enables antibiotic tolerance in Salmonella by preventing prophage induction through ATP depletion N2 - Antibiotic persistence comprises drug-tolerant bacteria that can survive treatment with antibacterial agents, despite lacking classical genetic resistance mechanisms. Therefore, persisters are clinically relevant because they can lead to treatment failures and chronic infections. Additionally, antibiotic persistence facilitates the evolution of resistance through genetic mutations. Persisters are triggered by a lack of nutrients, bacterial toxins, low ATP levels, or other stress responses that shut down bacterial metabolism. However, the involvement of prophages, viruses that integrate into bacterial chromosomes, is less well understood. In this study, we tested a tisAB deletion in Salmonella Typhimurium and examined persister cell formation following treatment with the DNA-damaging drug ciprofloxacin. TisB is a bacterial toxin that increases the influx of protons across the inner bacterial membrane into the cytosol, causing ATP depletion. We demonstrate that the deletion of tisAB increases prophage induction and bacterial killing, leading to a reduced persister cell fraction. The tisAB mutant is unable to down regulate its ATP concentration after exposure to ciprofloxacin, which in turn allows for stronger binding of RecA to single-stranded DNA, the activator of both the SOS response and prophage induction. KW - Antimicrobial resistance KW - Bacterial survival mechanisms KW - Escherichia coli KW - Salmonella typhimurium PY - 2025 DO - https://doi.org/10.1371/journal.ppat.1013498 IS - 9 SP - 1 EP - 23 AN - OPUS4-64642 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Nordholt, Niclas A1 - O'Hara, Kate A1 - Resch-Genger, Ute A1 - Blaskovich, M. A1 - Rühle, Bastian A1 - Schreiber, Frank T1 - A fluorescently labelled quaternary ammonium compound (NBD-DDA) to study resistance mechanisms in bacteria N2 - Quaternary ammonium compounds (QACs) are widely used as active agents in disinfectants, antiseptics, and preservatives. Despite being in use since the 1940s, there remain multiple open questions regarding their detailed mode-of-action and the mechanisms, including phenotypic heterogeneity, that can make bacteria less susceptible to QACs. To facilitate studies on resistance mechanisms towards QACs, we synthesized a fluorescent quaternary ammonium compound, namely N-dodecyl-N,N-dimethyl-[2-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]ethyl]azanium-iodide (NBD-DDA). NBD-DDA is readily detected by flow cytometry and fluorescence microscopy with standard GFP/FITC-settings, making it suitable for molecular and single-cell studies. As a proof-of-concept, NBD-DDA was then used to investigate resistance mechanisms which can be heterogeneous among individual bacterial cells. Our results reveal that the antimicrobial activity of NBD-DDA against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa is comparable to that of benzalkonium chloride (BAC), a widely used QAC, and benzyl-dimethyl-dodecylammonium chloride (BAC12), a mono-constituent BAC with alkyl-chain length of 12 and high structural similarity to NBD-DDA. Characteristic time-kill kinetics and increased tolerance of a BAC tolerant E. coli strain against NBD-DDA suggest that the mode of action of NBD-DDA is similar to that of BAC. As revealed by confocal laser scanning microscopy (CLSM), NBD-DDA is preferentially localized to the cell envelope of E. coli, which is a primary target of BAC and other QACs. Leveraging these findings and NBD-DDA‘s fluorescent properties, we show that reduced cellular accumulation is responsible for the evolved BAC tolerance in the BAC tolerant E. coli strain and that NBD-DDA is subject to efflux mediated by TolC. Overall, NBD-DDA’s antimicrobial activity, its fluorescent properties, and its ease of detection render it a powerful tool to study resistance mechanisms of QACs in bacteria and highlight its potential to gain detailed insights into its mode-of-action. KW - Antimicrobial resistance KW - Bacteria KW - Disinfection KW - Biocides PY - 2022 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-563811 DO - https://doi.org/10.3389/fmicb.2022.1023326 SN - 1664-302X IS - 13 SP - 1 EP - 13 PB - Frontiers Media CY - Lausanne AN - OPUS4-56381 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Valentin, J. A1 - Straub, H. A1 - Pietsch, Franziska A1 - Lemare, M. A1 - Ahrens, C. A1 - Schreiber, Frank A1 - Webb, J. A1 - van der Mei, H. A1 - Ren, Q. T1 - Role of the flagellar hook in the structural development and antibiotic tolerance of Pseudomonas aeruginosa biofilms N2 - Pseudomonas aeruginosa biofilms exhibit an intrinsic resistance to antibiotics and constitute a considerable clinical threat. In cystic fibrosis, a common feature of biofilms formed by P. aeruginosa in the airway is the occurrence of mutants deficient in flagellar motility. This study investigates the impact of flagellum deletion on the structure and antibiotic tolerance of P. aeruginosa biofilms, and highlights a role for the flagellum in adaptation and cell survival during biofilm development. Mutations in the flagellar hook protein FlgE influence greatly P. aeruginosa biofilm structuring and antibiotic tolerance. Phenotypic analysis of the flgE knockout mutant compared to the wild type (WT) reveal increased fitness under planktonic conditions, reduced initial adhesion but enhanced formation of microcolony aggregates in a microfluidic environment, and decreased expression of genes involved in exopolysaccharide formation. Biofilm cells of the flgE knock-out mutant display enhanced tolerance towards multiple antibiotics, whereas its planktonic cells show similar resistance to the WT. Confocal microscopy of biofilms demonstrates that gentamicin does not affect the viability of cells located in the inner part of the flgE knock-out mutant biofilms due to reduced penetration. These findings suggest that deficiency in flagellar proteins like FlgE in biofilms and in cystic fibrosis infections represent phenotypic and evolutionary adaptations that alter the structure of P. aeruginosa biofilms conferring increased antibiotic tolerance. KW - Antimicrobial resistance KW - Bacteria KW - Biofilms KW - Biocides PY - 2021 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-541113 DO - https://doi.org/10.1038/s41396-021-01157-9 SN - 1751-7370 VL - 16 IS - 4 SP - 1176 EP - 1186 PB - Springer Nature AN - OPUS4-54111 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Li, M. A1 - Schlaich, C. A1 - Zhang, J. A1 - Donskyi, Ievgen A1 - Schwibbert, Karin A1 - Schreiber, Frank A1 - Xia, Y. A1 - Radnik, Jörg A1 - Schwerdtle, T. A1 - Haag, R. T1 - Mussel-inspired multifunctional coating for bacterial infection prevention and osteogenic induction N2 - Bacterial infection and osteogenic integration are the two main problems that cause severe complications after surgeries. In this study, the antibacterial and osteogenic properties were simultaneously introduced in biomaterials, where copper nanoparticles (CuNPs) were generated by in situ reductions of Cu ions into a mussel-inspired hyperbranched polyglycerol (MI-hPG) coating via a simple dip-coating method. This hyperbranched polyglycerol with 10 % catechol groups’ modification presents excellent antifouling property, which could effectively reduce bacteria adhesion on the surface. In this work, polycaprolactone (PCL) electrospun fiber membrane was selected as the substrate, which is commonly used in biomedical implants in bone regeneration and cardiovascular stents because of its good biocompatibility and easy post-modification. The as-fabricated CuNPs-incorporated PCL membrane [PCL-(MI-hPG)-CuNPs] was confirmed with effective antibacterial performance via in vitro antibacterial tests against Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and multi-resistant E. coli. In addition, the in vitro results demonstrated that osteogenic property of PCL-(MI-hPG)-CuNPs was realized by upregulating the osteoblast-related gene expressions and protein activity. This study shows that antibacterial and osteogenic properties can be balanced in a surface coating by introducing CuNPs. KW - Mussel-inspired coating KW - CuNPs KW - Multi-resistant bacteria KW - Antibacterial KW - Antifouling KW - Osteogenesis PY - 2021 DO - https://doi.org/10.1016/j.jmst.2020.08.011 SN - 1005-0302 VL - 68 SP - 160 EP - 171 PB - Elsevier Ltd. AN - OPUS4-51519 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Feller, Viktor A1 - Mielentz, Frank A1 - Klewe, T. A1 - Krause, Martin A1 - Orglmeister, R. A1 - Pflugradt, M. T1 - Ultrasonic phased array for investigations of concrete components N2 - This paper describes an innovation of a phased array using dry contact probes to test concrete components. Based on preceding work on pressure waves, a low-frequency ultrasonic phased array consisting of shear wave probes is used in the experiments. This configuration allows the variation and control of the sound field directivity during the measurement. The measurements are carried out on a concrete test block using a scanning laservibrometer and a scanner system in transmission mode. The laboratory measurements are compared to theoretical calculations to investigate the influence of the probes shape and dimension on the resulting sound field patterns. The comparison of the modelling and the measurements demonstrates the suitability of the point source synthesis as a tool for the optimization of probe array designs. Methods of coded are used to improve the signal to noise ratio. T2 - NDT-CE 2015 - International symposium non-destructive testing in civil engineering CY - Berlin, Germany DA - 15.09.2015 KW - Ultrasonic KW - Phased array KW - Concrete KW - Point source synthesis PY - 2015 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-350417 UR - http://www.ndt.net/article/ndtce2015/papers/059_feller_viktor.pdf SN - 1435-4934 SP - 1 EP - 5 PB - Technische Universität Berlin / Bundesanstalt für Materialforschung und -prüfung AN - OPUS4-35041 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Abbas, Ioana M. A1 - Schwaar, Timm A1 - Bienwald, Frank A1 - Weller, Michael G. T1 - Predictable Peptide Conjugation Ratios by Activation of Proteins with Succinimidyl Iodoacetate (SIA) N2 - The small heterobifunctional linker succinimidyl iodoacetate (SIA) was examined for the preparation of peptide–protein bioconjugates with predicable conjugation ratios. For many conjugation protocols, the protein is either treated with a reductant to cleave disulfide bonds or is reacted with thiolation chemicals, such as Traut’s reagent. Both approaches are difficult to control, need individual optimization and often lead to unsatisfactory results. In another popular approach, a heterobifunctional linker with a N-hydroxysuccinimide (NHS) and a maleimide functionality is applied to the protein. After the activation of some lysine ε-amino groups with the NHS ester functionality, a cysteine-containing peptide is attached to the activated carrier protein via maleimide. Particularly, the maleimide reaction leads to some unwanted byproducts or even cleavage of the linker. Many protocols end up with conjugates with unpredictable and irreproducible conjugation ratios. In addition, the maleimide-thiol addition product should be assumed immunogenic in vivo. To avoid these and other disadvantages of the maleimide approach, we examined the known linker succinimidyl iodoacetate (SIA) in more detail and developed two protocols, which lead to peptide–protein conjugates with predefined average conjugation ratios. This holds potential to eliminate tedious and expensive optimization steps for the synthesis of a bioconjugate of optimal composition. KW - Bioconjugate KW - Carrier protein KW - Immunogen KW - Hapten KW - Linker KW - Antibody drug conjugate KW - ADC KW - Drug-to-antibody ratio KW - DAR KW - Conjugation ratio KW - Conjugation density KW - Carrier load KW - Click reaction KW - Click chemistry PY - 2017 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-427188 UR - http://www.mdpi.com/2409-9279/1/1/2 DO - https://doi.org/10.3390/mps1010002 SN - 2409-9279 VL - 1 SP - 1 EP - 14 PB - MDPI CY - Basel, Schweiz AN - OPUS4-42718 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Gonzalez III, F. A1 - Prabhakaran, A. A1 - Robitaille, A. A1 - Booth, G. A1 - Birk, A.M. A1 - Otremba, Frank T1 - Rail tank car total containment fire testing: planning & test development N2 - Given the frequent incidences of Non-Accident Releases (NARs) of hazardous materials from tank cars, there in an increasing interest in transporting hazardous materials in total containment conditions (i.e., no pressure relief devices). However, the ability of tank cars to meet thermal protection requirements provided in the Code of Federal Regulations under conditions of total containment has not been established. Also, the modeling tool commonly used by industry to evaluate thermal protection, AFFTAC, has not been validated under these conditions. The intent of this effort was to evaluate through a series of third-scale fire tests, the ability of tank cars to meet the thermal protection requirements under total containment conditions, and also, to validate AFFTAC for such conditions. This paper describes the test design and planning effort associated with this research, including the design and evaluation of a fire test setup to simulate a credible, fully engulfing, pool fire that is consistent and repeatable, and the design and hydro-static testing of a third-scale tank specimen. The fire design includes controls on the spatial distribution and temperature variation of the flame temperature, the heat flux, and the radiative balance, to best reflect large liquid hydrocarbon pool fire conditions that may be experienced during derailment scenarios. T2 - JRC2015 - Joint rail conference CY - San Jose, CA, USA DA - 23.03.2015 PY - 2015 SP - 5764, 1 EP - 6 AN - OPUS4-32985 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wolf, Julia A1 - Mielentz, Frank A1 - Milmann, Boris A1 - Helmerich, Rosemarie A1 - Köpp, Christian A1 - Wiggenhauser, Herbert A1 - Kurz, J.H. A1 - Moryson, R.M. A1 - Samokrutov, A. A1 - Alekhin, S. G. A1 - Alver, Ninel A1 - Sazak, H.Ö. T1 - An ultrasound monitoring system for concrete structures N2 - The research project "Ultrasonic Net for Concrete Monitoring (UNeCOM)" aims at developing a methodology for an embedded ultrasonic network for the condition assessment of infrastructure constructions. Civil engineering structures made of concrete, which are located in tectonically active regions or undergo special loading conditions, may require continuous monitoring. It is important to assess the condition of the building and its stability to recognise and classify the effect of a seismic event or evolving damage at early stages before failure occurs. Embedded ultrasonic sensors offer the possibility to detect changes in the material and degradation mechanisms from inside the structure in areas which are difficult or impossible to inspect otherwise. In contrast to conventional ultrasonic testing methods, where the concrete surfaces are scanned with ultrasound probes, this new approach uses sensors, which are embedded into concrete, eliminating the effect of variable coupling conditions between sensors and concrete. This method allows an integral detection of changes in the concrete structure, for example due to seismic activities, to detect mechanical impacts, as well as degradation of the material due to overloading. Such methods have great relevance especially for the monitoring of constructions like power plants, bridges, offshore structures and other structures with high technical safety requirements. The sensor network can be controlled remotely through the internet which is also being used for data transfer. The embedded sensor network is designed to monitor structural damage and concrete degradation globally with high sensitivity. T2 - Istanbul bridge conference 2014 CY - Istanbul, Turkey DA - 11.08.2014 KW - Ultrasound KW - Concrete KW - Monitoring PY - 2014 SN - 978-605-64131-6-2 SP - Paper 32, 1 EP - 9 AN - OPUS4-32028 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Jentsch, H. A1 - Schwartz, A. A1 - Basedau, Frank A1 - Bazrafshan, K. A1 - Döring, H. A1 - Großwig, S. A1 - Hofmann, Detlef A1 - Kowalle, G. A1 - Kusche, Nadine A1 - Lorenz, R. A1 - Pfeiffer, T. A1 - Sadaghiani, M.R.S. A1 - Scholz, E. A1 - Senze, A. A1 - Tkachenko, Viktoriya A1 - Witt, K. J. ED - Xu, Y. L. ED - Zhu, S. ED - Xia, Y. ED - Ni, Y.Q. ED - Law, S.S. ED - Yin, J. H. ED - Su, Z.Q. T1 - Detection of slipping soil areas with embedded tiny vertical sensing rods N2 - Critical soil zones where large areas along a shear joint might begin to slip should be recognized. In order to avoid damage, monitoring of such unstable zones is necessary. First, soil movements must be detected as early as possible, second, the amount of deformation should be estimated. Because geodetical methods do not provide information about deformation in the underground in different depths, the only way to come to information from possible shear zones is the installation of deformation measurement systems. A special installation method was developed to bring a long-gauge length measurement system into a borehole and transfer data of soil deformations into an installed sensing rod. The mostly vertically installed sensing rod has an outer diameter of 3 mm to 6 mm and contains several optical fibres. One fibre provides integral strain information along the whole length of the rod. To get this information, the phase difference between the fibre input and output is measured and the change of the total length of the fibre can be derived. This easy and cheap online sensing system delivers an early warning of soil deformations respectively possible slip as well as landslides. In case of warning, the second sensing system based on Fibre Bragg Grating sensors located close to the expected shear zone purposefully. It records resulting deformations in detail. In this study, three main objectives were achieved: a) development of tiny pultruded sensing rods with integrated optical sensor fibres, b) installation technology which enables the integration of the sensing rod during drilling and pile driving, and c) development of a stiff but elastic racking material to fix the rod in the soil and to transfer soil deformation into the stiffer sensing rod. These three aspects including the fibre optical measurement systems are described; results from Press Deformation Test (PDT) are presented. Test results of the fibre optical online system are compared and evaluated with the results of conventional inclinometer measurements as well as numerical modelling. An outlook for further possibilities of usage of this monitoring system is given. T2 - SHMII-6 - 6th International conference on structural health monitoring of intelligent infrastructure CY - Hong Kong, China DA - 09.12.2013 KW - Structural health monitoring KW - Soil stability monitoring KW - Optical fibre strain-sensor KW - Geotechnical soil stability KW - Soil deformation modelling PY - 2013 SN - 978-962-367-768-4 SP - 1 EP - 9 AN - OPUS4-29915 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Bradley, I. A1 - Birk, A.M. A1 - Otremba, Frank A1 - Gonzalez III, F. A1 - Prabhakaran, A. A1 - Bisby, L. T1 - Development and characterisation of an engulfing hydrocarbon pool fire test for hazardous materials pressure vessels N2 - The US Department of Transportation, Federal Railroad Administration (FRA) current regulations for rail tank cars in the United States stipulate that, for certain hazardous materials, tank cars shall have a thermal protection system capable of preventing rupture of the tank for 100 minutes when exposed to an engulfing fire with a blackbody equivalent flame temperature of 871 °C (+/- 56°C), and that tanks shall have a pressure relief device set at an appropriate level (depending on the type of tank car and contents). Pressure relief devices are a source of non-accident releases, and hence may cause serious incidents when tanks are transporting hazardous materials. Industry in North America would therefore benefit from removal of pressure relief devices on tanks transporting certain hazardous materials. Such an approach is known as full Containment, and is standard practice in Europe. In 2014 the FRA commissioned an experimental study to investigate the ability of a specific design of rail tank to resist rupture without incorporating a pressure release valve. As a precursor to tests on tanks there was a need to develop and characterise a simulated pool fire capable of reliably exposing large-scale tanks to repeatable, uniform conditions. This paper describes such a fire test setup, developed using a burner array system fuelled by liquid propane and designed to produce luminous, low velocity flames representative of those found in large hydrocarbon pool fires. The experimental set-up is described, along with the Instrumentation (directional flame thermometers, infra-red camera, and thermally massive calorimeter) and methodology used to characterise the fire. Comparisons are made against previous fire tests on vessels to assess the suitability of the experimental set-up for future vessel testing. T2 - CONFAB 2015 - 1st International conference on structural safety under fire & blast CY - Glasgow, UK DA - 02.09.2015 PY - 2015 SP - 485 EP - 494 AN - OPUS4-34545 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Esteban-Fernández, D. A1 - Bierkandt, Frank A1 - Linscheid, M.W. T1 - MeCAT labeling for absolute quantification of intact proteins using labelspecific isotope dilution ICP-MS N2 - Sensitive, accurate and fast absolute quantification of intact proteins is reported using metal coded affinity tags (MeCATs) combined with gel electrophoresis (GE) separation, inductively coupled plasma mass spectrometry (ICP-MS) detection and label-specific isotope dilution analysis quantification. Two different approaches were investigated concerning the introduction of the sample into ICP-MS, mineralization of the gel and direct laser ablation (LA) of the spot. Three major advantages are remarkable in the proposed method. First, not only heteroatom-containing proteins but also all labeled proteins in the sample can be absolutely quantified preparing an isotopically enriched tracer. On the other hand, highly sensitive determination in the amol range can be performed, considerably reducing the analysis time due to the straightforward measurements by ICP-MS. Furthermore, the studied method allows accurate quantifications with different sample-to-spike ratios and using stock spikes stored for months. After the first characterization using standard proteins, human serum albumin (HSA) and transferrin (Tf) were determined in human serum to test the applicability of the method to biological samples. The results show satisfactory quantifications for the studied proteins despite the difference in concentration and the similarity in migration distances. PY - 2012 DO - https://doi.org/10.1039/c2ja30137g SN - 0267-9477 SN - 1364-5544 VL - 27 IS - 10 SP - 1701 EP - 1708 PB - Royal Society of Chemistry CY - London AN - OPUS4-27777 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wolf, Julia A1 - Milmann, Boris A1 - Helmerich, Rosemarie A1 - Köpp, Christian A1 - Mielentz, Frank A1 - Wiggenhauser, Herbert A1 - Kurz, J.H. A1 - Moryson, R.-M. A1 - Samokrutov, A. A1 - Alekhin, S. G. A1 - Alver, Ninel A1 - Sazak, H.-Ö. ED - Xu, Y. L. ED - Zhu, S. ED - Xia, Y. ED - Ni, Y.Q. ED - Law, S.S. ED - Yin, J. H. ED - Su, Z.Q. T1 - Ultrasound based monitoring system for concrete monolithic objects N2 - Ultrasound sensors should be embedded into concrete for monitoring concrete properties. These new longitudinal wave sensors with a center frequency of 60 kHz were examined regarding their suitability for ultrasonic measurements in concrete structures in terms of emission characteristics, sensitivity and frequency ränge. For the measurement of the radiation patterns, the sensors were embedded vertically and horizontally in concrete cylinders. The directivity pattern was measured using a laser vibrometer. The sensitivity of the sensor was determined in water using different sensors of the same type. It shows changes in the signal amplitude as well as variations in the frequency ränge for different transmitter-receiver combinations. The attenuation of the concrete affects the achievable resolution of the measurements and thus, the maximum possible spacing of the sensors within a concrete element. Experimental tests helped optimizing the distances with respect to the required resolution and the effort of embedding the sensors. The signal attenuation in the concrete was measured in the frequency ränge of 60 kHz in response to various degrees of reinforcement and grain size. For this purpose, the sensors were cast at different distances in the specimens studied. The recorded Signals were evaluated for their amplitude and frequency spectrum. T2 - SHMII-6 - 6th International conference on structural health monitoring of intelligent infrastructure CY - Hong Kong, China DA - 09.12.2013 KW - Ultrasound KW - Concrete KW - Monitoring system KW - Ultrasonic network KW - Embedded sensor PY - 2013 SN - 978-962-367-768-4 SP - 1 EP - 6 AN - OPUS4-29642 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Heap, M.J. A1 - Lavallée, Y. A1 - Laumann, A. A1 - Hess, K.-U. A1 - Meredith, P.G. A1 - Dingwell, D.B. A1 - Huismann, Sven A1 - Weise, Frank T1 - The influence of thermal-stressing (up to 1000 °C) on the physical, mechanical, and chemical properties of siliceous-aggregate, high-strength concrete N2 - High-strength concrete (HSC) will experience thermal microcracking, explosive spalling, and undesirable chemical changes when exposed to high temperatures, such as during fire, engulfment by lava flow, or nuclear meltdown. Knowledge of the resultant changes in mechanical, physical, and chemical properties is paramount for hazard mitigation. We present a multidisciplinary study on the influence of thermal-stressing on HSC. Our study shows that thermal microcracking in HSC initiates at 180 °C, is more prevalent during cooling, and exhibits the Kaiser 'temperature-memory' effect. We show that residual compressive strength, indirect tensile strength, ultrasonic wave velocities, and Young’s modulus and Poisson’s ratio decrease, whilst porosity and permeability increase with increasing temperature. We discuss these data in terms of the chemical changes during thermal-stressing, provided by thermo-gravimetric analysis, differential scanning calorimetry, and X-ray diffraction, and from optical microscopic analysis of thermally-stressed samples. We provide implications for thermally-damaged HSC structures and a new method for non-destructive monitoring. KW - High strength concrete KW - Fire KW - Thermal-stressing KW - Acoustic emissions KW - Physical properties KW - Elastic moduli KW - Uniaxial compressive strength KW - Indirect tensile strength KW - Thermo-gravimetric analysis KW - X-ray diffraction PY - 2013 DO - https://doi.org/10.1016/j.conbuildmat.2013.01.020 SN - 0950-0618 VL - 42 SP - 248 EP - 265 PB - Elsevier Ltd. CY - Amsterdam AN - OPUS4-27992 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -