TY - JOUR A1 - Gross, U. A1 - Müller-Mai, C. A1 - Voigt, C. A1 - Berger, Georg A1 - Spitzer, Andrea T1 - In Vivo Tests of a Highly Porous Rapidly Resorbable Dicalcium Potassium Sodium Phosphate Glass-Ceramics N2 - Glass-ceramics containing Ca2KNa(PO4)2 as the main crystalline phase have a solubility which is 8 times higher than that of alpha-tricalcium phosphate ceramics. When using these compositions in drug delivery systems, especially in bone, it is necessary to create a material with a high open porosity. A Ca2KNa(PO4)2-based glass-ceramic was prepared from a borosilicate glass melt. The processed material includes minor amounts of boron which are low enough for medical application. Tissue response was studied using an animal model. Particles were implanted in rabbit femurs. Bone and soft tissue development occurred at the particle interfaces. In general, most particles were enclosed in the network of trabecular bone. The advantages of using a biomaterial with high porosity (pore size of 1-3 micron), together with rapid biodegradation, bioactivity and biocompatibility, despite traces of boron, were shown. 4 refs. T2 - 14th International Symposium on Ceramics in Medicine CY - Palm Springs, CA, USA DA - 2001-11-14 PY - 2002 U6 - https://doi.org/10.4028/www.scientific.net/KEM.218-220.307 SN - 1013-9826 VL - 218-220 SP - 307 EP - 310 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-1935 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gross, U. A1 - Müller-Mai, C. A1 - Voigt, C. A1 - Berger, Georg A1 - Spitzer, Andrea T1 - In vivo test of a high porous rapidly resorbable dicalcium potassium sodium phosphate glass-ceramics T2 - 14th International Symposium on Ceramics in Medicine ; Annual meeting of the International Society for Ceramics in Medicine 2001 CY - Palm Springs, CA, USA DA - 2001-11-14 PY - 2002 SN - 1013-9826 VL - 218-220 SP - 307 EP - 310 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-1893 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Spange, St. A1 - Müller, H. A1 - Jäger, Christian A1 - Bellmann, C. T1 - Fabrication of carbon/silica hybrid materials using cationic polymerization and the sol-gel process PY - 2002 SN - 1022-1360 SN - 0258-0322 SN - 1521-3900 VL - 177 IS - 1 SP - 111 EP - 124 PB - Wiley-VCH Verl. CY - Weinheim AN - OPUS4-11017 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -