TY - JOUR A1 - Berger, Wolfgang A1 - Bandow, Nicole A1 - Simon, Franz-Georg T1 - Untersuchungen zum Merkmalstransfer bei der Behandlung von Hausmüllverbrennungsasche N2 - In Deutschland fallen aktuell über 5 Mio. Tonnen Hausmüllverbrennungsaschen (HMVA) pro Jahr an. Aus diesen werden nur ca. 8 % Metalle (davon ca. 1 % NE-Metalle) zurückgewonnen. Zur Beurteilung des Wertstoffpotentials werden die HMVA nach standardisierten Vorschriften beprobt, für die Analytik vorbehandelt/vorbereitet/aufgearbeitet und auf ihre Inhaltsstoffe analysiert. Im nachfolgenden Beitrag wird der Schwerpunkt auf die Probenvorbehandlung und -vorbereitung gelegt, wobei der Merkmalstransfer von der Ausgangs-(Feld-)Probe über die Laborprobe und die Prüfprobe bis zur Mess-(Analysen-) Probe am Beispiel von NE-Metallen einer nassaufbereiteten HMVA untersucht wurde. Die Ergebnisse wurden mit Hilfe statistischer Methoden bewertet. Die Ergebnisse zeigen, dass die Verteilung der NE-Metalle in den einzelnen Schritten der Probenbehandlung elementspezifisch ist. Bei Blei ist ein Erhalt der Merkmalsverteilung über alle Behandlungsschritte erkennbar. Bei Kupfer nehmen die Konzentrationen in den aufeinander folgenden Behandlungsschritten deutlich ab. Die Ursache könnte das in der Feinfraktion enthaltene metallische Kupfer mit seinen spezifischen Eigenschaften sein. ------------------------------------------------------------------------------------------------------------------------------------------- More than 5 billion tons of municipal solid waste incineration bottom ashes (MSWI BA) are generated by incineration per year in Germany. Currently only 8 % of metals (of these 1 % are non-ferrous metals) are recovered from MSWI BA. For characterization of recovery potential, MSWI BA samples have to be taken, pre-treated and analyzed according to standardized methods. This manuscript focuses on sample pre-treatment and preparation of a MSWI BA sample aiming to investigate the characteristics transfer over the process of sub-sampling from the original (field) sample to the laboratory sample, test sample until the analytical sample. All results have been evaluated with statistical methods. The results show that influence of each single pre-treatment and preparation step on metal content differs for the individual metals. For lead a conservation of characteristics distribution can be observed, while for copper a continuous decline of solid concentration is observed over all preparation steps. One possible reason may be the fact that copper is mainly contained in the fine fraction as metallic copper with specific properties. KW - Hausmüllverbrennungsasche KW - Probenvorbehandlung und -vorbereitung KW - Merkmalstransfer KW - NE-Metalle KW - Statistische Auswertung PY - 2015 SN - 0027-2957 SN - 1863-9763 VL - 1 SP - 22 EP - 26 PB - Erich Schmidt CY - Berlin AN - OPUS4-32566 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Symietz, Christian A1 - Lehmann, Erhard A1 - Gildenhaar, Renate A1 - Krüger, Jörg A1 - Berger, Georg T1 - Femtosecond laser induced fixation of calcium alkali phosphate ceramics on titanium alloy bone implant material N2 - Femtosecond lasers provide a novel method of attaching bioceramic material to a titanium alloy, thereby improving the quality of bone implants. The ultrashort 30 fs laser pulses (790 nm wavelength) penetrate a thin dip-coated layer of fine ceramic powder, while simultaneously melting a surface layer of the underlying metal. The specific adjustment of the laser parameters (pulse energy and number of pulses per spot) avoids unnecessary melting of the bioactive calcium phosphate, and permits a defined thin surface melting of the metal, which in turn is not heated throughout, and therefore maintains its mechanical stability. It is essential to choose laser energy densities that correspond to the interval between the ablation fluences of both materials involved: about 0.1-0.4 J cm-2. In this work, we present the first results of this unusual technique, including laser ablation studies, scanning electron microscopy and optical microscope images, combined with EDX data. KW - Bone implant KW - Bioceramic coating KW - Titanium KW - Calcium phosphate KW - Femtosecond laser PY - 2010 DO - https://doi.org/10.1016/j.actbio.2010.02.016 SN - 1742-7061 VL - 6 IS - 8 SP - 3318 EP - 3324 PB - Elsevier CY - Amsterdam AN - OPUS4-21446 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Winkler, T. A1 - Hoenig, E. A1 - Huber, G. A1 - Janssen, R. A1 - Fritsch, D. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Morlock, M.M. A1 - Schilling, A.F. T1 - Osteoclastic bioresorption of biomaterials: Two- and three-dimensional imaging and quantification N2 - Purpose: Bioresorbable materials have been developed in the hope that the body will replace them with newly formed tissue. The first step of this remodeling process in bone is the bioresorption of the material by osteoclasts. The aim of this study was to analyze osteoclastic resorption of biomaterials in vitro using the commonly used two-dimensional methods of light-microscopy (LM) and scanning electron microscopy (SEM) in comparison with infinite focus microscopy (IFM), a recently developed imaging method allowing for three-dimensional surface analysis. Methods: Human hematopoietic stem cells were cultivated in the presence of the cytokines M-CSF and RANK-L for 4 weeks directly on dentin and a calcium phosphate cement. Osteoclast development was surveyed with standard techniques. After removal of the cells, resorption was characterized and quantified by LM, SEM and IFM. Results: Osteoclast cultures on the biomaterials presented the typical osteoclast-specific markers. On dentin samples LM, SEM as well as IFM allowed for discrimination of resorption. Quantification of the resorbed area showed a linear correlation between the results (LM vs. SEM: r=0.996, p=0.004; SEM vs. IFM: r=0.989, p=0.011; IFM vs. LM: r=0.995). It was not possible to demarcate resorption pits on GB14 using LM or SEM. With IFM, resorption on GB14 could be visualized and quantified two- and three-dimensionally. KW - Biomaterial KW - Three-dimensional KW - IFM KW - Osteoclast KW - Dentin KW - Calcium phosphate PY - 2010 SN - 0391-3988 VL - 33 IS - 4 SP - 198 EP - 203 PB - Wichtig Ed. CY - Milano [u.a.] AN - OPUS4-21621 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Müller-Mai, C.M. A1 - Berger, Georg A1 - Stiller, M. A1 - Gildenhaar, Renate A1 - Jörn, Daniela A1 - Ploska, Ute A1 - Houshmand, A. A1 - Bednarek, A. A1 - Koch, C. A1 - Knabe, C. T1 - Evaluation of degradable bone cements for percutaneous augmentation of bone defects KW - Bone defect KW - Bioactive bone cement KW - Calcium alkali orthophosphates KW - Histology KW - Histomorphometry KW - Knochendefekt KW - Bioaktiver Knochenzement KW - Calciumalkaliorthophosphat KW - Histologie KW - Histomorphometrie PY - 2010 DO - https://doi.org/10.1002/mawe.201000706 SN - 0933-5137 SN - 1521-4052 VL - 41 IS - 12 SP - 1040 EP - 1047 PB - Wiley-VCH Verl. CY - Weinheim AN - OPUS4-22891 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Offen porige Knochen-ersatzwerkstoffe auf Basis von Calcium-Alkali-Phosphaten T2 - 4. Workshop "Biomaterialien" des AK 15 (Mineralogische und Technische Kristallo-graphie) der Dt. Ges. f. Kristallographie (DGK) CY - Halle (Saale), Germany DA - 2008-10-06 PY - 2008 AN - OPUS4-18102 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Berger, Georg A1 - Acil, Y. A1 - Jepsen, S. A1 - Spitzer, Andrea ED - Ohgushi, H. T1 - Rapidly resorbable and spongiosa-like dicalcium potassium sodium phosphate glass-ceramics for three-dimensional cultivation of human osteoblast-like cells PY - 1999 SN - 981-024099-6 N1 - Serientitel: Bioceramics – Series title: Bioceramics IS - 12 SP - 233 EP - 236 PB - World Scientific CY - Singapore AN - OPUS4-19147 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Symietz, Christian A1 - Lehmann, Erhard A1 - Gildenhaar, Renate A1 - Krüger, Jörg A1 - Berger, Georg T1 - Fixierung resorbierbarer Knochenersatzkeramik auf Ti6Al4V-Implantatmaterial mittels Femtosekundenlaser T2 - 5. Thüringer Grenz- und Oberflächentage und 7. Thüringer Biomaterial-Kolloquium CY - Friedrichroda, Deutschland DA - 2009-09-15 KW - Metallprothese KW - Implantat KW - Knochenersatz KW - Bioaktives Material KW - Lasersintern KW - Femtosekundenlaser PY - 2009 SN - 978-3-00-028446-5 SP - 327 AN - OPUS4-20051 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Dombrowski, Felix A1 - Ploska, Ute A1 - Berger, Georg A1 - Gildenhaar, Renate A1 - Stiller, M. A1 - Knabe, C. ED - Kim, Sukyoung T1 - Rheological investigations on degradable and figuline calcium alkaline phosphate cements T2 - 22nd International symposium on ceramics in medicine (Bioceramics 22) CY - Daegu, Korea DA - 2009-10-26 KW - Rheology KW - Calcium alkaline phosphate cement KW - Gelatine KW - Composite PY - 2009 SP - 863 EP - 866 AN - OPUS4-20287 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Lehmann, Erhard A1 - Spitzer, Andrea ED - Kim, Sukyoung T1 - Preparation of calcium alkali phosphate implants by 3D-printing T2 - 22nd International symposium on ceramics in medicine (Bioceramics 22) CY - Daegu, Korea DA - 2009-10-26 KW - Bone substitute material KW - Calcium alkali phosphate KW - Resorbable bioceramics KW - 3D-printing process KW - Bending strength PY - 2009 SP - 71 EP - 74 AN - OPUS4-20288 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Winkler, T. A1 - Hoenig, E. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Fritsch, D. A1 - Janssen, R. A1 - Morlock, M.M. A1 - Schilling, A.F. T1 - Volumetric analysis of osteoclastic bioresorption of calcium phosphate ceramics with different solubilities N2 - Commonly, to determine osteoclastic resorption of biomaterials only the resorbed area is measured. The depth of the resorption pit, however, may also be important for the performance of a material. To generate such data we used two calcium phosphate ceramics (Ca10 and Ca2). The solubility of the materials was determined according to DIN EN ISO 10993-14. They were scanned three-dimensionally using infinite focus microscopy and subsequently cultivated for 4 weeks in simulated body fluid without (control) or with human osteoclasts. After this cultivation period osteoclasts number was determined and surface changes were evaluated two- and three-dimensionally. Ca10 and Ca2 showed solubilities of 11.0 ± 0.5 and 23.0 ± 2.2 mg g-1, respectively. Both materials induced a significant increase in osteoclast number. While Ca10 did not show osteoclastic resorption, Ca2 showed an increased pit area and pit volume due to osteoclastic action. This was caused by an increased average pit depth and an increased number of pits, while the average area of single pits did not change significantly. The deduced volumetric osteoclastic resorption rate (vORR) of Ca2 (0.01–0.02 µm3 µm-2 day-1) was lower than the remodelling speed observed in vivo (0.08 µm3 µm-2 day-1), which is in line with the observation that implanted resorbable materials remain in the body longer than originally expected. Determination of volumetric indices of osteoclastic resorption might be valuable in obtaining additional information about cellular resorption of bone substitute materials. This may help facilitate the development of novel materials for bone substitution. KW - Biodegradation KW - Surface analysis KW - Simulated body fluid KW - Osteoclasts KW - Calcium phosphate ceramics PY - 2010 DO - https://doi.org/10.1016/j.actbio.2010.04.015 SN - 1742-7061 VL - 6 IS - 10 SP - 4127 EP - 4135 PB - Elsevier CY - Amsterdam AN - OPUS4-22554 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Quillard, S. A1 - Paris, M. A1 - Deniard, P. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Obadia, L. A1 - Bouler, J.-M. T1 - Structural and spectroscopic characterization of a series of potassium- and/or sodium-substituted beta-tricalcium phosphate N2 - In this paper, we report X-ray diffraction investigations as well as Raman and solid-state 31P and 23Na magic angle spinning nuclear magnetic resonance (NMR) characterization of three series of calcium orthophosphates. The general formulae of the studied compounds are Ca10.5-x/2Mx(PO4)7, where M = K or Na and x = 0, 0.25, 0.50, 0.75, 1.0; and Ca10KxNa1-x(PO4)7, where x = 0, 0.25, 0.5, 0.75, 1.0. These calcium orthophosphates are found to be isostructural with β-tricalcium phosphate (β-TCP, Ca3(PO4)2) with the substitution of some calcium sites by potassium and/or sodium cations. The unit cell parameters vary continuously with the level of substitution, a characteristic of these solid solutions. The Raman spectra show the different vibrational bands of the phosphate groups PO4, while the NMR chemical shifts are sensitive to the non-equivalent phosphorus and sodium ions present in these substituted samples. As both Raman and NMR spectroscopies are local probes, they offer tools to distinguish between these different phosphorus and phosphate groups, according to their structural site and local environment, especially the type of cation substituent. A convenient decomposition of the Raman and NMR spectra into Gaussian–Lorentzian components leads us to propose an assignment of the main observed bands of these substituted β-TCPs. KW - Bioceramics KW - Tricalcium phosphate KW - X-ray diffraction KW - Raman spectroscopy KW - Solid-state NMR spectroscopy PY - 2011 DO - https://doi.org/10.1016/j.actbio.2010.12.016 SN - 1742-7061 VL - 7 IS - 4 SP - 1844 EP - 1852 PB - Elsevier CY - Amsterdam AN - OPUS4-23405 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Symietz, Christian A1 - Lehmann, Erhard A1 - Gildenhaar, Renate A1 - Koter, Robert A1 - Berger, Georg A1 - Krüger, Jörg T1 - Fixation of bioactive calcium alkali phosphate on Ti6Al4V implant material with femtosecond laser pulses N2 - Bone implants made of metal, often titanium or the titanium alloy Ti6Al4V, need to be surface treated to become bioactive. This enables the formation of a firm and durable connection of the prosthesis with the living bone. We present a new method to uniformly cover Ti6Al4V with a thin layer of ceramics that imitates bone material. These calcium alkali phosphates, called GB14 and Ca10, are applied to the metal by dip coating of metal plates into an aqueous slurry containing the fine ceramic powder. The dried samples are illuminated with the 790 nm radiation of a pulsed femtosecond laser. If the laser fluence is set to a value just below the ablation threshold of the ceramic (ca. 0.4 J/cm²) the 30 fs laser pulses penetrate the partly transparent ceramic layer of 20–40 µm thickness. The remaining laser fluence at the ceramic–metal interface is still high enough to generate a thin metal melt layer leading to the ceramic fixation on the metal. The laser processing step is only possible because Ti6Al4V has a lower ablation threshold (between 0.1 and 0.15 J/cm²) than the ceramic material. After laser treatment in a fluence range between 0.1 and 0.4 J/cm², only the particles in contact with the metal withstand a post-laser treatment (ultrasonic cleaning). The non-irradiated rest of the layer is washed off. In this work, we present results of a successful ceramic fixation extending over larger areas. This is fundamental for future applications of arbitrarily shaped implants. KW - Bone implant KW - Bioceramic coating KW - Titanium KW - Calcium phosphate KW - Femtosecond laser PY - 2011 DO - https://doi.org/10.1016/j.apsusc.2010.10.046 SN - 0169-4332 SN - 1873-5584 VL - 257 IS - 12 SP - 5208 EP - 5212 PB - North-Holland CY - Amsterdam AN - OPUS4-23310 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Maskos, Michael A1 - Berger, Georg A1 - Braun, Ulrike A1 - Heyn, Andreas A1 - Klinger, Christian A1 - Wachtendorf, Volker T1 - Schadensanalyse und Beständigkeit von Materialien in biomedizinischen Einsatzgebieten N2 - Der Anteil von Polymeren als Funktions- und Konstruktionswerkstoffe in dauerhaften medizinischen Anwendungen steigt beständig. Derartige Materialien müssen den mechanischen, biologischen und chemischen Bedingungen im Körper widerstehen (u.a. Abrieb, Hydrolyse, Degradation) und gleichzeitig gut verträglich sein. Der sichere Einsatz von polymeren Materialien erfordert die Kenntnisse über ihre Langzeitstabilität unter verschiedenen äußeren Bedingungen. Diese sind nicht nur beeinflusst durch die unmittelbare Umgebung in vivo, sondern auch durch die Historie der verwendeten Materialien. Dazu zählen u. a. erhöhte Temperaturen unter sauerstoffhaltiger Atmosphäre während der Verarbeitung oder die Exposition von ionisierender Strahlung oder reaktiven Radikalen während der Sterilisation. PY - 2011 SP - 83 EP - 85 CY - Berlin AN - OPUS4-23592 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Bernstein, A. A1 - Nöbel, D. A1 - Mayr, H.O. A1 - Göbel, F. A1 - Berger, Georg A1 - Ploska, Ute A1 - Gildenhaar, Renate A1 - Brandt, J. T1 - Inhibition of Mineralization by a Calcium Zirconium Phosphate Coating N2 - Bioactive ceramics used as coating materials combine the conductive properties of a bioceramic with the mechanical stability of the metal implant. We studied a calcium zirconium phosphate-containing coating material, FA-CZP [Ca5(PO4)3F, CaZr4(PO4)6], that is relatively insoluble in the biological milieu. The reaction of bone to this material was investigated histologically and histomorphometrically in an animal trial. Cylindrical Ti6Al4V specimens that had been coated with FA-CZP by plasma spraying were implanted in the femoral condyles of rabbits. The implants were left in place for 2, 4, 6, 12, and 14 weeks. FA-CZP led to impaired mineralization of the newly formed bone at the interface. Noncalcified osteoid was found throughout the whole study period. The layer seemed to become thicker with time. The mineralization disorder is evidently caused by zirconium ions. The presence of zirconium in the osteoid in contact with the implant was demonstrated by means of two different staining methods. KW - Mineralization KW - Toxicity KW - Coating(s) KW - Ceramic KW - Bone PY - 2008 DO - https://doi.org/10.1002/jbm.b.31037 SN - 1552-4973 SN - 1552-4981 VL - 86B IS - 2 SP - 422 EP - 429 PB - Wiley CY - Hoboken, NJ AN - OPUS4-17801 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Bernstein, A. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Mayr, H.O. T1 - In vitro an in vivo behaviour of a ceramic with interconnected macroporosity KW - Ceramics KW - Porosity KW - Biomaterial KW - Bone KW - Biocompatibility KW - Surface reaction PY - 2009 SN - 1013-9826 VL - 396-398 SP - 19 EP - 22 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-17880 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Jörn, Daniela A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Stiller, M. A1 - Knabe, C. T1 - Behaviour of calcium alkali orthophosphate cements under simulated implantation conditions KW - Calcium alkali orthophosphates KW - Calcium phosphate cement KW - Compressive strength KW - Setting times PY - 2009 SN - 1013-9826 VL - 396-398 SP - 213 EP - 216 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-17881 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Bielefeldt, Nicole A1 - Ploska, Ute A1 - Berger, Georg A1 - Heimann, L. T1 - Rapidly resorbable, temporarily mechanically stable composites for bone replacement KW - Hydroxyapatite KW - Gelatin KW - Composite KW - Degradation KW - Release property PY - 2009 SN - 1013-9826 VL - 396-398 SP - 469 EP - 472 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-17882 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Simon, Franz-Georg A1 - Berger, Wolfgang ED - Litz, N. ED - Wilcke, W. ED - Wilke, B.-M. T1 - Thermische Bodenbehandlung KW - Bodenbehandlung KW - Desorption KW - Pyrolyse KW - Verbrennung PY - 2008 SN - 978-3-527-32341-8 IS - Abschnitt IV-3.1.2 SP - 1 EP - 11 PB - Wiley-VCH CY - Weinheim AN - OPUS4-18185 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Krahl, Thoralf A1 - Gildenhaar, Renate A1 - Kenning, Hilke A1 - Berger, Georg A1 - Jäger, Christian ED - Kim, Sukyoung T1 - Predicting phase compositions of samples in the ternary system Ca2KNa(PO4)2-Ca3(PO4)2-Ca2P2O7 using 31P MAS NMR T2 - 22nd International symposium on ceramics in medicine (Bioceramics 22) CY - Daegu, Korea DA - 2009-10-26 KW - NMR KW - Bone substitute materials KW - Alkali calcium phosphates KW - TCP KW - Ca10(K,NA)(PO4)7 PY - 2009 SP - 11 EP - 14 AN - OPUS4-20656 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Knabe, C. A1 - Berger, Georg A1 - Gildenhaar, Renate A1 - Ducheyne, P. A1 - Stiller, M. T1 - Novel, rapidly resorbable bioceramic bone grafts produce a major osteogenic effect - the pre-clinical evidence KW - Calcium phosphates KW - Bone substitute materials KW - Bioactive ceramics KW - Biodegradability PY - 2010 DO - https://doi.org/10.4028/www.scientific.net/AST.76.214 SN - 1662-0356 VL - 76 SP - 214 EP - 223 PB - Techna CY - Faenza AN - OPUS4-22028 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gross, U. A1 - Müller-Mai, Ch. A1 - Berger, Georg A1 - Ploska, Ute T1 - Do Calcium Zirconium Phoshate Ceramics Inhibit Mineralization? KW - Calcium zirconium phosphate ceramics KW - Rabbit model KW - Tissue response KW - Impaired mineralisation KW - Inhibition of matrix vesicles PY - 2004 SN - 1013-9826 VL - 254-256 SP - 635 EP - 638 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2746 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ploska, Ute A1 - Berger, Georg A1 - Willfahrt, Manfred T1 - A new procedure of a calcium-containing coating on implants of titanium alloy KW - TiAl6V4 KW - Calcium titanate KW - Surface layer KW - Salt melt PY - 2004 SN - 1013-9826 VL - 254-256 SP - 411 EP - 414 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2747 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ploska, Ute A1 - Berger, Georg A1 - Sahre, Mario T1 - Investigation of the Influence of Zirconium Content on the Formation of Apatite on Bioactive Glass-Ceramics KW - Glass KW - Glass-ceramics KW - Zirconium KW - Bioactivity KW - SBF PY - 2004 SN - 1013-9826 VL - 254-256 SP - 71 EP - 74 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2748 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gildenhaar, Renate A1 - Bernstein, A. A1 - Berger, Georg A1 - Hein, W. T1 - In-vitro Surface Reactions of Bioceramic Materials KW - Ceramics KW - Coating KW - Biomaterial KW - Bone KW - Biocompatibility KW - Surface reaction PY - 2004 SN - 1013-9826 VL - 254-256 SP - 407 EP - 410 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2749 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Zreiqat, H. A1 - Berger, Georg A1 - Gildenhaar, Renate A1 - Knabe, Ch. T1 - The Functional Expression of Human Bone-Derived Cells Grown on Rapidly Resorbable Calcium Phosphate Ceramics KW - Calcium phosphate ceramics KW - Human bone-derived cells KW - Cell-biomaterial interactions KW - Bone-substitutes KW - in situ hybridization PY - 2004 UR - http://www.scientific.net/1013-9826/ SN - 1013-9826 VL - 254-256 SP - 1059 EP - 1062 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2750 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Amorphous calcium phosphate cements T2 - Program and Transactions. Fifth World Biomaterials Congress CY - Toronto, Canada DA - 1996-05-29 PY - 1996 AN - OPUS4-3284 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Biocompatible Werkstoffe - Ersatzteile für Menschen T2 - Podiumsdiskussion zur Materialica 2000 CY - Munich, Germany DA - 2000-06-29 PY - 2000 AN - OPUS4-3357 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Bioresorbable carriers for subchondral anchoring of tissue-engineered cartilage in articular defects T2 - Tissue Engineering Society International (TESI) meeting CY - Lake Buena Vista, FL, USA DA - 2000-11-30 PY - 2000 AN - OPUS4-3358 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Autologe Chondrozyten Transplantation durch Tissue Engineering auf resorbierbaren bioaktiven Biomaterialträgern T2 - 64. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie 2000 CY - Hanover, Germany DA - 2000-09-10 PY - 2000 AN - OPUS4-3334 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Calciumhaltiger resorbierbarer Knochenersatz - Beginn und aktuelle Entwicklungen T2 - 1. Workshop über Keramische Biomaterialien CY - Freiberg, Germany DA - 2002-06-14 PY - 2002 AN - OPUS4-3431 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Biocompatibility studies of a new bone cement using humane bone marrow cells - preliminary results T2 - 18. European Conference on Biomaterials CY - Stuttgart, Germany DA - 2003-10-01 PY - 2003 AN - OPUS4-4706 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Berger, Georg A1 - Gildenhaar, Renate A1 - Pauli, Jutta A1 - Marx, Heidi T1 - Preparation and Characterization of New Self-Setting Calcium Phosphate Cements Based on Alkali Containing Orthophosphates KW - P-31-NMR Investigation KW - Ca2KNa(PO4)2 KW - Calcium Alkali Orthophosphates KW - Calcium Phosphate Cement KW - Self-Setting Cement PY - 2005 SN - 1013-9826 VL - 284-286 SP - 121 EP - 124 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-5493 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ploska, Ute A1 - Gildenhaar, Renate A1 - Berger, Georg T1 - Resorbable Biomaterials Based on Calcium Phosphates: Determination of In Vitro Solubility Applying the ISO 10993-14 (First Experiences) KW - Calcium Phosphate KW - In Vitro Solubility KW - ISO Standard KW - Resorbable PY - 2005 SN - 1013-9826 VL - 284-286 SP - 485 EP - 488 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-5494 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Mücke, Udo A1 - Harbich, Karl-Wolfram A1 - Berger, Georg T1 - Bestimmung derVolumen- und Grenzflächendichte von Poren in spongiosa-ähnlichen Glaskeramiken mit der Bildanalyse und Röntgenrefraktion / Determination of the Volume and Surface Densities of Pores in Spongiosa-Like Glass Ceramics by Means of Image Analysis and X-ray Refraction PY - 2004 SN - 0032-678X N1 - Sprachen: Deutsch/Englisch - Languages: German/English VL - 41 IS - 8 SP - 386 EP - 396 PB - Hanser CY - München AN - OPUS4-5978 LA - mul AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Bernstein, A. A1 - Lehmann, Erhard ED - Degischer, H.-P. T1 - Neue Biokeramiken für den Plasmaspritzprozess T2 - 14. Symposium Verbundwerkstoffe und Werkstoffverbunde CY - Wien, Österreich DA - 2003-07-02 PY - 2003 SN - 3-527-30762-1 SP - 732 EP - 737 PB - Wiley-VCH CY - Weinheim AN - OPUS4-5983 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Bernstein, A. A1 - Brandt, J. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Hein, W. T1 - The Bone Reaction to Ceramic Coated Pins - Animal Study KW - Biocompatibility KW - Biomaterial KW - Bone KW - Ceramics KW - Coating KW - Surface Reaction KW - Biokeramik KW - Beschichtung KW - Knochenersatz KW - Biomompatibilität PY - 2005 SN - 1013-9826 VL - 284-286 SP - 179 EP - 182 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-5495 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Preparation and Characterization of New Self-setting Calcium Phosphate Cements Based on Alkali Containing Orthophophates T2 - 17th Annual Meeting of the international Society for Ceramics in Medicine CY - New Orleans, LA, USA DA - 2004-12-08 PY - 2004 AN - OPUS4-5877 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Bernstein, A. A1 - Berger, Georg A1 - Brandt, J. A1 - Wenkel, R. A1 - Gildenhaar, Renate A1 - Zielezinski, T. A1 - Nöbel, D. T1 - Calciumtitanat (Ca4Ti3O10) - ein neues Material für Implantatbeschichtungen KW - Implantatbeschichtung KW - Calciumtitanat KW - Bioaktivität KW - Knochenkontakt KW - Biomaterial-bone-coating of an implant PY - 2004 SN - 1616-0177 SN - 0011-8656 VL - 5 IS - 4 SP - 242 EP - 248 PB - Verl. Neuer Merkur CY - München AN - OPUS4-6010 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Offenporige keramiken für den Knochensatz T2 - Vorlesung im Rahmen der RIngvorlesung 0334 VL 113 "Aufbau und Eigenschaften moderner Biomaterialien", Technische Universität Berlin/Humboldt Universität zu Berlin, Charité/Freie Universität Berlin CY - Berlin, Germany DA - 2002-01-28 PY - 2002 AN - OPUS4-6190 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Biokeramikentwicklung an der BAM T2 - 9. Keramik-Tag der BAM CY - Berlin, Germany DA - 2002-05-23 PY - 2002 AN - OPUS4-6191 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Knabe, C. A1 - Howlett, C. R. A1 - Markovic, B. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Zreiqat, H. T1 - The Functional Expression of Osteoblasts Grown on Rapid Resorbable Calcium Phosphates T2 - 15th International Symposium on Ceramics in Medicine ; 15th Annual meeting of the International Society for Ceramics in Medicine ; 15th Bioceramics CY - Sydney, NSW, Australia DA - 2002-12-04 KW - Guided bone regeneration KW - Calcium alkali orthophosphates KW - Osteoblasts KW - Cell differentiation PY - 2003 SN - 1013-9826 VL - 240-242 SP - 679 EP - 682 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2115 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gross, U. A1 - Müller-Mai, Ch. A1 - Berger, Georg A1 - Ploska, Ute T1 - The Tissue Response to a Novel Calcium Zirconium Phosphate Ceramics T2 - 15th International Symposium on Ceramics in Medicine ; 15th Annual meeting of the International Society for Ceramics in Medicine ; 15th Bioceramics CY - Sydney, NSW, Australia DA - 2002-12-04 KW - Ceramics KW - Calcium Zirconium Phosphate KW - Rabbit model KW - Tissue response KW - Impaired mineralisation PY - 2003 SN - 1013-9826 VL - 240-242 SP - 629 EP - 632 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2116 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Berger, Georg A1 - Mücke, Udo A1 - Harbich, Karl-Wolfram T1 - Determination of the internal surface of spongiosa-like ceramic scaffolds using light microscopy and X-ray refraction techniques N2 - This paper deals with spongiosa-like resorbable bone substitution material or scaffolds created by using Ca2KNa(PO4)6 as main crystalline phase. The material is prepared by melting, shock-cooling meanwhile the melt spontaneously crystallizes, milling to powder used to make a slip for PUR-sponge (Schwarzwalder process), and sintering. The spongiosa-like material is analyzed to characterize the pores but also the material surrounding the pores as well as the resulting internal surface by light microscopy and X-ray refraction technique, respectively. There is a big difference between the measured internal surface by the methods mentioned. Further investigations show that the differences are the result of powder particles that are not integrated in the sinter process. Introduction Ceramic scaffolds made of resorbable bone substitution material usefully have been appropriated as bone defect filling material as well as cell substrate. The spongiosa-like material was prepared using calcium phosphates consisting mainly of Ca2KNa(PO4)2 that is rapidly resorbable in comparison to tricalcium phosphate ceramics. For characterization of micro-structural parameters we used light microscopy image analysis and X-ray refraction technique. The later one enabled to determine characteristic microstructure parameters, i.e. spatially resolved internal surface densities and corresponding pore size distributions of spongiosa-like bioceramics. Methods The synthesis of glass-ceramics containing Ca2KNa(PO4)2 as the main crystalline phase has been described in detail elsewhere [1, 2]. T2 - 15th International Symposium on Ceramics in Medicine CY - Sydney, NSW, Australia DA - 2002-12-04 KW - Resorbable Ceramics KW - Ca2KNa(PO4)2 KW - Scaffolds KW - X-ray refraction technique KW - Internal surface PY - 2003 DO - https://doi.org/10.4028/www.scientific.net/KEM.240-242.469 SN - 1013-9826 VL - 240-242 SP - 469 EP - 472 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2117 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Berger, Georg A1 - Ploska, Ute T1 - Long-Term Stable Biomaterials Based on Apatite and Calcium Zirconium Orthophosphate T2 - 15th International Symposium on Ceramics in Medicine ; 15th Annual meeting of the International Society for Ceramics in Medicine ; 15th Bioceramics CY - Sydney, NSW, Australia DA - 2002-12-04 KW - Bioceramics KW - Apatite KW - Calcium zirconium phosphate KW - Chemical stability PY - 2003 SN - 1013-9826 VL - 240-242 SP - 607 EP - 610 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-2118 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Bernstein, A. A1 - Hein, W. T1 - In-Vitro Surface Reactions of Plasma Sprayed Bioceramics T2 - International Symposium "Interface Biology of Implants" CY - Rostock, Germany DA - 2003-05-15 PY - 2003 SN - 1616-0177 SN - 0011-8656 VL - 4 IS - 2 SP - 106 PB - Verl. Neuer Merkur CY - München AN - OPUS4-2595 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Bernstein, A. A1 - Gildenhaar, Renate A1 - Nöbel, D. A1 - Berger, Georg T1 - Biocompatibility screening of different calcium phosphate ceramics PY - 2003 SN - 1616-0177 SN - 0011-8656 VL - 4 IS - 2 SP - 89 PB - Verl. Neuer Merkur CY - München AN - OPUS4-2596 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Müeller, W.-D. A1 - Gross, U. A1 - Fritz, Th. A1 - Voigt, Ch. A1 - Fischer, P. A1 - Berger, Georg A1 - Rogaschewski, S. A1 - Lange, K.-P. T1 - Evaluation of the interface between bone and titanium surfaces being blasted by aluminium oxide or bioceramic particles N2 - The surface structure, in particular the surface roughness, and the surface chemistry of titanium implants influence their anchoring in bone. The aim of this study was to analyse metal-bone contact (MBC) after modification of the implant surface, using different materials for blasting. The surface modification of titanium was produced by blasting it with particles made of Al2O3 or bioceramics. The biological effects were then investigated experimentally using 27 rabbits, analysed after 7, 28 and 84 days after the implantation of titanium cylinders treated accordingly. The MBC showed a tendency for more bone after bioceramics were used as a blasting material, compared to Al2O3. KW - Dental implants KW - Surface modification KW - Animal experiment KW - Bioceramics PY - 2003 DO - https://doi.org/10.1034/j.1600-0501.2003.00791.x SN - 0905-7161 SN - 1600-0501 VL - 14 IS - 3 SP - 349 EP - 356 PB - Blackwell Munksgaard CY - Oxford AN - OPUS4-3506 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Gross, U. A1 - Müller-Mai, C. A1 - Knabe, C. A1 - Berger, Georg A1 - Ploska, Ute A1 - Gildenhaar, Renate ED - Vincenzini, P. T1 - Animal experiments with biomaterials for direct bone contact displaying higher or lower solubility in comparison to TCP and HA products T2 - 10th International Ceramics Congress ; 3rd Forum on New Materials ; 10th CIMTEC 2002 CY - Florence, Italy DA - 2002-07-14 PY - 2004 SP - 369 EP - 376 PB - Techna CY - Faenza AN - OPUS4-3500 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Knabe, Ch. A1 - Berger, Georg A1 - Gildenhaar, Renate A1 - Klar, F. A1 - Zreiqat, H. T1 - The modulation of osteogenesis in vitro by calcium titanium phosphate coatings N2 - Calcium phosphate coated titanium and titanium alloy are widely used as dental and orthopaedic implants. This study examines the effect of novel calcium titanium and calcium titanium zirconium phosphates suitable for plasma-spraying onto titanium substrata on the expression of bone-related genes and proteins by human bone-derived cells (HBDC) and compares this behavior to that on native titanium and hydroxyapatite-coated titanium. Test materials were an acid etched and sand-blasted titanium surface (Ti-DPS), a plasma-sprayed hydroxyapatite coating (HA), and five materials which were created from CaTi4(PO4)6 (CTP) and CaZr4(PO4)6 (CZP): sintered CaTi4(PO4)6 (CTP-S1), sintered 46CaO·23TiO2·31P2O5 (CTP-S2), sintered CaTiZr3(PO4)6, (CTZP-S1), sintered 46CaO·23ZrO2·31P2O5 (CTZP-S2) and sintered 55CaO·20TiO2·31P2O5 (CTP-S3). HBDC were grown on the substrata for 3, 7, 14 and 21 d, counted and probed for various mRNAs and proteins (type I collagen, osteocalcin, osteopontin, osteonectin, alkaline phosphatase and bone sialoprotein). All substrates significantly affected cellular growth and the temporal expression of an array of bone-related genes and proteins. At 14 and 21 d, cells on CTP-S3 displayed significantly enhanced expression of all osteogenic mRNAs. Surfaces of CTP-S1 and CTP-S3 had the most effect on osteoblastic differentiation inducing a greater expression of an array of osteogenic markers than recorded for cells grown on Ti-DPS and HA, suggesting that these novel materials may possess a higher potency to enhance osteogenesis. KW - Calcium phosphate coatings KW - Osteoblast KW - In vitro test KW - In situ hybridization KW - Osteogenesis PY - 2004 DO - https://doi.org/10.1016/j.biomaterials.2004.01.059 SN - 0142-9612 VL - 25 IS - 20 SP - 4911 EP - 4919 PB - Elsevier CY - Oxford AN - OPUS4-3501 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Knabe, C. A1 - Berger, Georg A1 - Gildenhaar, Renate A1 - Meyer, J. A1 - Howlett, C. A1 - Markovic, B. A1 - Zreiqat, H. T1 - Effect of rapidly resorbable calcium phosphates and a calcium phosphate bone cement on the expression of bone-related genes and proteins in vitro N2 - The use of biodegradable bone substitutes is advantageous for alveolar ridge augmentation because it avoids second-site surgery for autograft harvesting. This study examines the effect of novel, rapidly resorbable calcium phosphates and a calcium phosphate bone cement on the expression of bone-related genes and proteins by human bone-derived cells (HBDCs) and compares this behavior to that of tricalciumphosphate (TCP). Test materials were -TCP, two materials with a crystalline phase Ca2KNa(PO4)2 and with a small amorphous portion containing either magnesium potassium phosphate (material denominated GB14) or silica phosphate (material denominated GB9), and a calcium phosphate bone cement (material denominated Biocement D). HBDCs were grown on the substrata for 3, 7, 14, and 21 days, counted, and probed for various mRNAs and proteins (type I collagen, osteocalcin, osteopontin, osteonectin, alkaline phosphatase, and bone sialoprotein). All substrates supported continuous cellular growth for 21 days. In the presence of GB14 and Biocement D specimens cell proliferation was reduced and cell differentiation increased. At day 21, the greatest number of cells was found on GB9 expressing significantly higher levels of bone-related proteins than cells grown on all other surfaces. Because all novel materials facilitated the expression of the osteoblastic phenotype at least as much as TCP and the polystyrene control, these biomaterials can be regarded as excellent candidate bone substitute materials. GB9 induced the highest proliferation and cellular differentiation after 21 days of incubation, suggesting that this material may possess a higher potency for enhancing osteogenesis than TCP. © 2004 Wiley Periodicals, Inc. J Biomed Mater Res 69A: 145-154, 2004 KW - Calcium phosphate ceramics KW - Human bone-derived cells KW - Cell-biomaterial interactions KW - Calcium phosphate cements KW - In situ hybridization PY - 2004 DO - https://doi.org/10.1002/jbm.a.20131 SN - 1549-3296 SN - 1552-4965 VL - 69 IS - 1 SP - 145 EP - 154 PB - Wiley CY - Hoboken, NJ AN - OPUS4-3502 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Harbich, Karl-Wolfram A1 - Mücke, Udo A1 - Berger, Georg T1 - Characterisation of highly porous glass ceramic scaffolds N2 - Schwammartige glaskeramische Biowerkstoffe werden zunehmend als Knochenersatzmaterial verwendet und sind bereits im Tierversuch erprobt. Für den optimalen Einsatz dieser gut resorbierbaren Biowerkstoffe ist eine zuverlässige Charakterisierung erforderlich. Im Vordergrund stehen dabei der Herstellungsprozess, über den die offene Porosität kontrolliert eingestellt wird, sowie der Sintervorgang, der die Struktur des keramischen Gerüstmaterials entscheidend prägt. Hier werden mittels Röntgenrefraktionsanalyse und lichtoptischer Bildauswertung sowohl Porosität als auch die innere Oberflächendichte bestimmt. Während mit beiden Verfahren die Porositäten gut übereinstimmen, weichen die Oberflächendichten signifikant voneinander ab. Dieser Unterschied ist hauptsächlich auf mikrostrukturelle Defekte im keramischen Werkstoffgefüge zurückzuführen, die von der Bildanalyse quantitativ nur unvollständig erfasst werden. Dagegen ist die bildanalytische Auswertung der typischen, großporigen Hohlraumstruktur im Vergleich zur Röntgenrefraktion von Vorteil. Die Untersuchungen zeigen, dass die Kombination beider Verfahren eine geeignete Ergänzung darstellt, um die Strukturparameter verlässlich bestimmen zu können. Dies ist auch die wesentliche Voraussetzung für die Optimierung der Materialeigenschaften. KW - Glaskeramische Biowerkstoffe KW - Innere Oberflächen KW - Porosität KW - Röntgenrefraktionsanalyse KW - Lichtoptische Bildanalyse PY - 2004 DO - https://doi.org/10.3139/120.100585 SN - 0025-5300 VL - 46 IS - 5 SP - 243 EP - 247 PB - Carl Hanser Verlag CY - München AN - OPUS4-3740 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Klaffke, Dieter A1 - Berger, Georg A1 - Hartelt, Manfred T1 - Tribologische Untersuchungen an Ti-6Al-4V mit und ohne Calciumtitanat-Reaktionsschicht KW - Reibung KW - Verschleiß KW - Ti-6Al-4V KW - Calciumtitanat KW - Friction KW - Wear KW - Calcium titanate PY - 2004 SN - 1616-0177 SN - 0011-8656 VL - 5 IS - 2 SP - 67 EP - 70 PB - Verl. Neuer Merkur CY - München AN - OPUS4-3684 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -