TY - JOUR A1 - Knabe, Ch. A1 - Berger, Georg A1 - Gildenhaar, Renate A1 - Howlett, C.R. A1 - Markovic, B. A1 - Zreiqat, H. T1 - The functional expression of human bone-derived cells grown on rapidly resorbable calcium phosphate ceramics N2 - The use of biodegradable bone substitutes is advantageous for alveolar ridge augmentation, since it avoids second-site surgery for autograft harvesting. This study examines the effect of novel, rapidly resorbable calcium phosphates on the expression of bone-related genes and proteins by human bone-derived cells (HBDC) and compares this behavior to that of tricalciumphosphate (TCP). Test materials were a-TCP, and four materials which were created from ß-Rhenanite and its derivatives: R1-ß-Rhenanite (CaNaPO4); R1/M2 composed of CaNaPO4 and MgNaPO4; R1+SiO2 composed of CaNaPO4 and 9% SiO2 (wt%); and R17-Ca2KNa(PO4)2. HBDC were grown on the substrata for 3, 5, 7, 14 and 21 days, counted and probed for various mRNAs and proteins (Type I collagen, osteocalcin, osteopontin, osteonectin, alkaline phosphatase and bone sialoprotein). All substrata supported continuous cellular growth for 21 days. At day 21, surfaces of R1+SiO2 and R17 had the highest number of HBDC. At 14 and 21 days, cells on R1 and on R1+SiO2 displayed significantly enhanced expression of all osteogenic proteins. Since all novel calcium phosphates supported cellular proliferation together with expression of bone-related proteins at least as much as TCP, these ceramics can be regarded as potential bone substitutes. R1 and R1+SiO2 had the most effect on osteoblastic differentiation, thus suggesting that these materials may possess a higher potency to enhance osteogenesis than TCP. KW - Calcium phosphate ceramics KW - Human bone-derived cells KW - Cell-biomaterial interactions KW - Bone substitutes KW - In situ hybridization PY - 2004 DO - https://doi.org/10.1016/S0142-9612(03)00525-8 SN - 0142-9612 VL - 25 IS - 2 SP - 335 EP - 344 PB - Elsevier CY - Oxford AN - OPUS4-2957 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Resorbierbaer Knochenersatz auf der Basis alkalihaltiger Calciumphosphate T2 - 2. Workshop "Biokeramik" der Deutschen Mineralogischen Gesellschaft CY - Freiberg, Germany DA - 2003-10-06 PY - 2003 AN - OPUS4-5289 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Resorbierbarer Knochenersatz auf Basis von Calciumphosphaten T2 - Kolloqium der Abt. für Funktionswerkstoffe der Medizin und Zahnheilkunde der Universitätsklinik und Polikliniken für Zahn-, Mund- und Kieferkrankheiten der Bayrischen Maximilians-Universität Würzburg CY - Würzburg, Germany DA - 2004-06-16 PY - 2004 AN - OPUS4-5375 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Resorbierbarer anorganischer Knochenersatz T2 - 20. Symposium und Workshop "Experimentelle Osteologie" der Orthopädischen Klinik der Martin-Luther-Universität Halle-Wittenberg CY - Halle (Saale), Germany DA - 2004-07-02 PY - 2004 AN - OPUS4-5378 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Werkstoffentwicklung für Medizin und Biotechnologie in der BAM-Projektgruppe "Biowerkstoffe und Implantate" T2 - Eingeladener Vortrag zum Institutskolloquium des Biotechnologisch-Biomedizinischen Zentrums der Universität Leipzig CY - Leipzig, Germany DA - 2004-10-20 PY - 2004 AN - OPUS4-5379 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Entwicklung von resorbierbarem Knochenersatz T2 - Eingeladener Vortag zum "Wissenschaftlichen Dialog" anläßlich der Eröffnung des Implantationszentrums an der Meoclinic Berlin CY - Berlin, Germany DA - 2004-11-13 PY - 2004 AN - OPUS4-5380 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Resorbable Bone Substitution Materials on the Basis of Calcium Phosphates T2 - 2. Treffen des DKG-Arbeitskreises "Glasig-kristalline Multifunktionswerkstoffe" CY - Saarbrücken, Germany DA - 2004-02-26 PY - 2004 AN - OPUS4-5372 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Resorbable bioceramic coated pins: solubility behaviour in vitro and adequate reactions in vivo T2 - IX. Conference of the European Ceramic Society (ECERS) CY - Portorož, Slovenia DA - 2005-06-19 PY - 2005 AN - OPUS4-7814 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Lehmann, Erhard A1 - Stiller, M. A1 - Koch, C. A1 - Ducheyne, P. A1 - Rack, A. A1 - Seligmann, H. A1 - Jonscher, S. A1 - Knabe, C. T1 - A comparative study of the biodegradability of calcium-alkali-orthophosphate ceramics in vitro and in vivo KW - Calcium-alkali-orthophosphate KW - Solubility KW - Biodegradability PY - 2007 SN - 1013-9826 VL - 330-332 SP - 63 EP - 66 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-14528 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ploska, Ute A1 - Berger, Georg T1 - Spongiosa-like Specimen and Foils of a Biomaterial Composed of Fluorapatite and Calcium Zirconium Phosphate KW - Apatite KW - Calcium zirconium phosphate KW - Spongiosa-like specimen KW - Foil PY - 2007 SN - 1013-9826 VL - 330-332 IS - Bioceramics 19 SP - 443 EP - 446 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-14529 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Marx, Heidi A1 - Berger, Georg A1 - Breitwieser, M. T1 - Prüftechnik für anorganischen Biozement KW - Gillmoore-Needle-Test KW - Initiale Abbindezeit KW - Finale Abbindezeit KW - Härtetest KW - Biozemente PY - 2007 SN - 0016-3538 VL - 51 IS - 2 SP - 106 EP - 108 PB - GIT-Verlag CY - Darmstadt AN - OPUS4-14582 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ploska, Ute A1 - Berger, Georg A1 - Jörn, Daniela A1 - Willfahrt, Manfred A1 - Hackbarth, Andreas T1 - Calcium titanate reaction layers on TiAl6V4 implants KW - Titan alloy KW - Calcium titanate KW - Reaction layer KW - Implant PY - 2008 SN - 1013-9826 VL - 361-363 SP - 657 EP - 660 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-15899 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Bernstein, A. A1 - Nöbel, D. A1 - Mayr, H.O. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Ploska, Ute A1 - Brandt, J. T1 - Influence of Calcium Zirconium Phosphate Containing Coatings on Mineralization of Bone KW - Ceramics KW - Coating KW - Biomaterial KW - Bone KW - Biocompatibility KW - Surface reaction PY - 2008 SN - 1013-9826 VL - 361-363 SP - 641 EP - 644 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-15900 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Beranic Klopcic, S. A1 - Pribosic, I. A1 - Kosmac, T. A1 - Ploska, Ute A1 - Berger, Georg T1 - The Reactivity of CaTi4(PO4)6 with Alumina and Y-TZP Ceramics KW - Calcium titanium phosphate KW - Alumina KW - Zirconia PY - 2008 SN - 1013-9826 VL - 361-363 SP - 787 EP - 790 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-15901 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Lehmann, Erhard A1 - Knabe, C. T1 - Development of Alkali Containing Calcium Phosphate Cements KW - Calcium phosphate cement KW - Calcium potassium sodium phosphate KW - Potassium containing apatite KW - Bone substitute materials PY - 2008 SN - 1013-9826 VL - 361-363 SP - 331 EP - 334 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-15902 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Calciumphosphat-Keramik für den resorbierbaren Knochenersatz T2 - Jahrestagung der Deutschen Keramischen Gesellschaft 2007 CY - Dresden, Germany DA - 2007-03-19 PY - 2007 AN - OPUS4-15863 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Schnell resorbierbare, offenporige Knochenersatzwerkstoffe auf Basis von Calciumphosphaten T2 - Symposium "Materialforschung für Innovation in der Region Berlin/Brandenburg" CY - Potsdam, Germany DA - 2007-09-27 PY - 2007 AN - OPUS4-15864 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Kalbe, Ute A1 - Berger, Wolfgang A1 - Simon, Franz-Georg A1 - Eckardt, Jürgen A1 - Christoph, Gabriele T1 - Results of interlaboratory comparisons of column percolation tests N2 - Laboratory leaching tests may be used for source term determination as a basis for risk assessment for soil–groundwater pathway (leachate forecast) on contaminated sites in Germany. Interlaboratory comparisons on the evaluation of the reproducibility of column percolation tests were conducted within the framework of an integrated R + D program using three waste reference materials. The interlaboratory comparisons of column percolation tests showed good reproducibility of the results for inorganic and organic parameters as well as for the accompanying parameters. This is due to the stipulations concerning the time of contact between leachant and sample material as well as the sample placement in the columns. Different column dimensions used by the participants of the interlaboratory comparisons did not have any substantial influence on the column test results. KW - Leachate forecast KW - Column percolation tests KW - Interlaboratory comparisons KW - Contaminated soil KW - Waste material PY - 2007 DO - https://doi.org/10.1016/j.jhazmat.2007.03.039 SN - 0304-3894 VL - 148 IS - 3 SP - 714 EP - 720 PB - Elsevier CY - Amsterdam AN - OPUS4-15754 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Simon, Franz-Georg A1 - Berger, Wolfgang A1 - Mantyk, Matthias T1 - Rückgewinnung von Kupfer aus Rostaschen aus der thermischen Abfallbehandlung KW - Flotation KW - Ressourcen KW - Rostasche PY - 2007 SN - 0026-0746 VL - 61 IS - 11 SP - 713 PB - Giesel Verlag GmbH CY - Isernhagen AN - OPUS4-16122 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Knabe, C. A1 - Houshmand, A. A1 - Berger, Georg A1 - Ducheyne, P. A1 - Gildenhaar, Renate A1 - Kranz, I. A1 - Stiller, M. T1 - Effect of rapidly resorbable bone substitute materials on the temporal expression of the osteoblastic phenotype in vitro N2 - Ideally, bioactive ceramics for use in alveolar ridge augmentation should possess the ability to activate bone formation and, thus, cause the differentiation of osteoprogenitor cells into osteoblasts at their surfaces. Therefore, in order to evaluate the osteogenic potential of novel bone substitute materials, it is important to examine their effect on osteoblastic differentiation. This study examines the effect of rapidly resorbable calcium-alkali-orthophosphates on osteoblastic phenotype expression and compares this behavior to that of β-tricalcium phosphate (TCP) and bioactive glass 45S5. Test materials were three materials (denominated GB14, GB9, GB9/25) with a crystalline phase Ca2KNa(PO4)2 and with a small amorphous portion containing either magnesium potassium phosphate (GB14) or silica phosphate (GB9 and GB9/25, which also contains Ca2P2O7); and a material with a novel crystalline phase Ca10[K/Na](PO4)7 (material denominated 352i). SaOS-2 human bone cells were grown on the substrata for 3, 7, 14, and 21 days, counted, and probed for an array of osteogenic markers. GB9 had the greatest stimulatory effect on osteoblastic proliferation and differentiation, suggesting that this material possesses the highest potency to enhance osteogenesis. GB14 and 352i supported osteoblast differentiation to the same or a higher degree than TCP, whereas, similar to bioactive glass 45S5, GB9/25 displayed a greater stimulatory effect on osteoblastic phenotype expression, indicating that GB9/25 is also an excellent material for promoting osteogenesis. KW - Bone substitute materials KW - Calcium-alkali-orthophosphate ceramics KW - SaOS-2 cells KW - Osteoblast differentiation KW - Bioactive glass PY - 2008 DO - https://doi.org/10.1002/jbm.a.31383 SN - 1549-3296 SN - 1552-4965 VL - 84A IS - 4 SP - 856 EP - 868 PB - Wiley CY - Hoboken, NJ AN - OPUS4-16658 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Dombrowski, Felix A1 - Marx, Heidi A1 - Ploska, Ute A1 - Nicolaides, Dagmar A1 - Stiller, M. A1 - Knabe, C. A1 - Berger, Georg T1 - Solubility and ingrowth behaviour of degradable and figuline calcium alkaline phosphate cements N2 - The thrust of the investigations presented here is to point out the degradation behaviour in vitro and the ingrowth behaviour in vivo of four different calcium alkaline phosphate cements. Two of the figuline and mouldable composites consist of the crystalline phase Ca2KNa(PO4)2 and two of the crystalline phase Ca10[K/Na](PO4)2 each containing 2wt% medium gel strength porcine gelatin. Furthermore A-TCP was added to both Ca10[K/Na](PO4)2 cements as a hardening supporting reactant. The testing material groups differ in small amorphous portions containing either silica phosphate (GB9), magnesium potassium phosphate (GB14) or diphosphates (401545 and 401545(70)). The respective composites show a monomodal particle size distribution (d50~7µm; span~4) and an average total porosity around 28vol%.For the solubility studies cylindrical samples (d=6mm; h=12mm) were stored in a 0.1mol TRIS buffer solution and incubated at 37°C for maximum 50 weeks. The storage solution was analysed and renewed every week. The results are plotted cumulative. For the in vivo studies critical size defects were dissected to mandibles in a sheep model in which a 1cm³ area of the bottom of the mandibles was surgically resected and replaced with the figuline cements whereas the mouldability allows the reconstruction of the original outer contour without draining off even when replacing upside down. KW - Calcium alkaline phosphate cement KW - Gelatin KW - Figuline KW - Solubility KW - Ingrowth behavior PY - 2012 DO - https://doi.org/10.4028/www.scientific.net/KEM.493-494.387 SN - 1013-9826 VL - 493-494 SP - 387 EP - 390 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-24924 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Dombrowski, Felix A1 - Hoffmann, Rita A1 - Ploska, Ute A1 - Marx, Heidi A1 - Berger, Georg T1 - Investigations on degradable and figuline calcium alkaline phosphate cements with multimodal particle size distribution N2 - The paper presented here deals with rheological and hardening properties during the setting reaction, and density and compressive strength after the final setting of a figuline composite consisting of Ca2KNa(PO4)2 and 2wt% medium gel strength gelatin. Compared to the composite with monomodal particle size distribution (d50=7.18µm; span=3.9) and its properties during and after setting reaction, the goal of this work is to increase the resulting product compressive strength by mixing different particle sizes in order to obtain bi- and trimodal distributions. For the bimodal powder mixtures the ratio in diameter (dcourse/dsmall) was chosen with 7/1 and volume ratio dcourse/dsmall was 70/30%. For the trimodal powder mixtures the ratio in diameter (dcourse/dmedium/dsmall) was chosen with 70/7/1 and volume ratio dcourse/dmedium/dsmall was set to 44/28/28%.After establishing an adequate crushing and sieving process the tap density and powder density of each fraction was determined. Subsequently, the different particle sizes were mixed and the densities and the Hausner ratio were determined again. The mixtures show an increase in both densities especially the tap density increased significantly. Rheological investigations show that the graphs of storage and loss moduli of the multimodal powder mixtures respectively are similar. The characteristic setting times show a slight decrease compared with the monomodal composite but not significantly different data. When comparing the resulting compressive strength of cylindrical samples, which were stored direct after reaching the initial setting time under physiological conditions, the studies illustrated in all cases for the multimodal mixtures a significant increase in compressive strength and a higher density. KW - Calcium alkaline phosphate cement KW - Gelatin KW - Compressive strength KW - Figuline KW - Particle size PY - 2012 DO - https://doi.org/10.4028/www.scientific.net/KEM.493-494.355 SN - 1013-9826 VL - 493-494 SP - 355 EP - 360 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-24925 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gildenhaar, Renate A1 - Knabe, C. A1 - Wirth, Cynthia A1 - Linow, Ulf A1 - Houshmand, A. A1 - Berger, Georg T1 - Calcium alkaline phosphate scaffolds for bone regeneration 3D-fabricated by additive manufacturing N2 - Calcium alkaline phosphate granulates can be used for substitution of several bone defects but for the reconstruction of large skeletal parts in the maxillofacial and orthopaedic fields fitted scaffolds are preferable. Within the additive manufacturing methods, the 3D printing process offers exciting opportunities to generate defined porous scaffolds. We used a R1 printer from ProMetal Company, USA, for producing scaffolds directly from a ceramic powder. For this direct free form fabrication technology the powder has to possess a lot of specific properties both for the generation of a stable green body and also for the subsequent sintering preparation. For this printing process we prepared different granules in a fluidized bed process containing Ca2KNa(PO4)2 as main crystalline phase. Granules were characterized by different methods and several sieve fractions were used for preparing disc like and cylindrical parts. The suitability of granules for this printing process was determined by porosity and strength of produced bodies. Next to granules' performance both of these properties can be directly influenced by 3D printing process parameters. With knowledge of suitable process parameters scaffolds with different porosity in a respective desired design can be created. In this study, cylindrical scaffolds with graded porosity were produced for bone regeneration of segmental defects in maxillofacial surgery and dental implantology by tissue engineering. KW - 3D printing KW - Calcium alkaline phosphates KW - Ceramic scaffolds KW - Oral surgery PY - 2012 DO - https://doi.org/10.4028/www.scientific.net/KEM.493-494.849 SN - 1013-9826 N1 - Geburtsname von Wirth, Cynthia: Gomes, C. M. - Birth name of Wirth, Cynthia: Gomes, C. M. VL - 493-494 SP - 849 EP - 854 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-24989 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Quillard, S. A1 - Mellier, C. A1 - Gildenhaar, Renate A1 - Hervelin, J. A1 - Deniard, P. A1 - Berger, Georg A1 - Bouler, J.-M. T1 - Raman and infrared studies of substituted ß-TCP N2 - Several substituted β-tricalcium phosphates have been prepared with different cations (monovalent, divalent and trivalent) and at various levels of substitution. Structural investigations have proved that fewer than ~10% wt substitution, the substituted compounds are isostructural to β-TCP, leading to solid solutions. These samples have been characterized by infrared and Raman spectroscopies. The vibrational spectra show mainly the bands related to the vibrations of PO43- tetrahedrons present in the structure. As Raman scattering and infrared absorption are local probes, the bands are sensitive to the local environment of the distinct tetrahedrons, related to the site of substitution and to the nature of the cations. KW - Tricalcium phosphates KW - Ionic substitution KW - Vibrational spectroscopies PY - 2012 DO - https://doi.org/10.4028/www.scientific.net/KEM.493-494.225 SN - 1013-9826 VL - 493-494 SP - 225 EP - 230 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-24954 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Simon, Franz-Georg A1 - Holm, Olaf A1 - Berger, Wolfgang T1 - Resource recovery from urban stock, the example of cadmium and tellurium from thin film module recycling N2 - Raw material supply is essential for all industrial activities. The use of secondary raw material gains more importance since ore grade in primary production is decreasing. Meanwhile urban stock contains considerable amounts of various elements. Photovoltaic (PV) generating systems are part of the urban stock and recycling technologies for PV thin film modules with CdTe as semiconductor are needed because cadmium could cause hazardous environmental impact and tellurium is a scarce element where future supply might be constrained. The paper describes a sequence of mechanical processing techniques for end-of-life PV thin film modules consisting of sandblasting and flotation. Separation of the semiconductor material from the glass surface was possible, however, enrichment and yield of valuables in the flotation step were non-satisfying. Nevertheless, recovery of valuable metals from urban stock is a viable method for the extension of the availability of limited natural resources. KW - Flotation KW - Cadmium KW - Tellurium KW - Thin film technology KW - Sand blasting PY - 2013 DO - https://doi.org/10.1016/j.wasman.2012.12.025 SN - 0956-053X VL - 33 IS - 4 SP - 942 EP - 947 PB - Pergamon Press CY - New York, NY AN - OPUS4-29312 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg A1 - Mensing, M. A1 - Müller-Mai, C. A1 - Gross, U. A1 - Rahmanzadeh, R. A1 - Sittinger, M. T1 - Bioresorbable carriers for subchondral anchoring of tissue-engineered cartilage in articular defects T2 - 3rd Biennial Meeting of the Tissue Engineering Society International (TESI) CY - Lake Buena Vista, FL, USA DA - 2000-11-30 PY - 2000 AN - OPUS4-1042 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Berger, Georg A1 - Ploska, Ute A1 - Gross, U. A1 - Mesgarian, M. A1 - Müller-Mai, Ch. A1 - Voigt, C. T1 - Tissue response in the femur of rabbits after implantation of a new calcium titanium phosphate composition KW - Bone Bonding KW - Calcium Titanium Phosphate KW - Coated Implants KW - Tissue Response PY - 2001 SN - 1013-9826 VL - 192-195 SP - 383 EP - 386 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-1044 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Berger, Georg A1 - Ploska, Ute A1 - Willmann, G. T1 - Hydroxyapatite's Solubility May Cause Loosening of Coated Implants KW - pH Value KW - Solubility KW - Coated Implants KW - Hydroxyapatite PY - 2001 SN - 1013-9826 VL - 192-195 SP - 111 EP - 114 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-1045 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Berger, Georg A1 - Ploska, Ute A1 - Willmann, G. T1 - Auflösung von Hydroxylapatit-Beschichtung durch Entzündung PY - 2001 SN - 1616-0177 SN - 0011-8656 VL - 2 IS - 2-3 SP - - PB - Verl. Neuer Merkur CY - München AN - OPUS4-1142 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Spongiosa-artige Formkörper und poröse Folien aus Calciumphosphat-Keramiken T2 - Statusseminar Bio-Med.Net - Tissue Engineering und zellbasierte Therapie in der Region Berlin CY - Berlin, Deutschland DA - 2001-06-29 PY - 2001 SP - 7 EP - 8 AN - OPUS4-1151 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Klaffke, Dieter A1 - Berger, Georg A1 - Hartelt, Manfred T1 - Tribologische Untersuchungen an anorganischen Implantatwerkstoffen PY - 2002 SN - 1616-0177 SN - 0011-8656 VL - 3 IS - 1 SP - 42 EP - 47 PB - Verl. Neuer Merkur CY - München AN - OPUS4-1332 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ploska, Ute A1 - Berger, Georg T1 - A new long-term stable biomaterial containing Apatite and Calcium-Zirconium-Orthophosphate PY - 2002 SN - 0957-4530 SN - 1573-4838 VL - 13 IS - 12 SP - L54 PB - Springer CY - Norwell, Mass. AN - OPUS4-1421 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Hitzegrad, Frank A1 - Berger, Georg A1 - Ploska, Ute A1 - Öchsner, A. T1 - Comparison of static and dynamical analysis material properties of opencell ZrO2 foams T2 - Materials Week 2002 ; European Congress on Advanced Materials, their Processes and Applications ; 6th International Conference on Joining Ceramics, Glass and Metal CY - Munich, Germany DA - 2002-09-30 PY - 2002 SN - 3-88355-314-X PB - Werkstoff-Informationsges. AN - OPUS4-1462 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hitzegrad, Frank A1 - Berger, Georg T1 - Untersuchung viskoelastischer Eigenschaften von porösen biokeramischen Werkstoffen und Bestimmung der durch applikationsbedingten Medieneinfluss verursachten Eigenschaftsänderungen T2 - Kolloquium des Lehrstuhls für Technische Mechanik CY - Erlangen, Deutschland DA - 2002-07-15 PY - 2002 AN - OPUS4-1463 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hitzegrad, Frank A1 - Berger, Georg A1 - Ploska, Ute A1 - Oechsner, A. ED - Claussen, N. T1 - Comparison of static and dynamic material properties of spongiosa-like bioceramics T2 - 8th International Conference on Ceramic Processing (ICCPS-8) CY - Hamburg, Germany DA - 2002-09-02 PY - 2004 SN - 0955-2219 VL - 24 IS - 2 PB - Elsevier CY - Orlando, FL AN - OPUS4-1464 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Berger, Georg A1 - Acil, Y. A1 - Jepsen, S. A1 - Spitzer, Andrea T1 - Rapidly resorbable and spongiosa-like dicalcium potassium sodium phosphate glass-ceramics for three-dimensional cultivation of human osteoblast-like cells T2 - 14th International Symposium on Ceramics in Medicine ; Annual meeting of the International Society for Ceramics in Medicine CY - Palm Springs, CA, USA DA - 2001-11-14 PY - 2002 UR - http://www.scientific.net/1013-9826/ SN - 1013-9826 VL - 218-220 SP - 233 EP - 236 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-1934 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gross, U. A1 - Müller-Mai, C. A1 - Voigt, C. A1 - Berger, Georg A1 - Spitzer, Andrea T1 - In Vivo Tests of a Highly Porous Rapidly Resorbable Dicalcium Potassium Sodium Phosphate Glass-Ceramics N2 - Glass-ceramics containing Ca2KNa(PO4)2 as the main crystalline phase have a solubility which is 8 times higher than that of alpha-tricalcium phosphate ceramics. When using these compositions in drug delivery systems, especially in bone, it is necessary to create a material with a high open porosity. A Ca2KNa(PO4)2-based glass-ceramic was prepared from a borosilicate glass melt. The processed material includes minor amounts of boron which are low enough for medical application. Tissue response was studied using an animal model. Particles were implanted in rabbit femurs. Bone and soft tissue development occurred at the particle interfaces. In general, most particles were enclosed in the network of trabecular bone. The advantages of using a biomaterial with high porosity (pore size of 1-3 micron), together with rapid biodegradation, bioactivity and biocompatibility, despite traces of boron, were shown. 4 refs. T2 - 14th International Symposium on Ceramics in Medicine CY - Palm Springs, CA, USA DA - 2001-11-14 PY - 2002 DO - https://doi.org/10.4028/www.scientific.net/KEM.218-220.307 SN - 1013-9826 VL - 218-220 SP - 307 EP - 310 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-1935 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Knabe, C. A1 - Howlett, C. A1 - Markovic, B. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Zreiqat, H. T1 - The functional expression of human osteoblasts grown on resorbable calcium phosphates N2 - The use of biodegradable bone substitutes is advantageous for alveolar ridge augmentation, since it avoids second-site surgery for autograft harvesting. This study examines the effect of novel, rapidly resorbable calcium phosphates on the expression of bone-related genes and proteins by human bone derived cells (HBDC) and compares this behavior to that of tricalciumphosphate (TCP). Test materials were -TCP, a newly synthesized chemical Ca2KNa(PO4)2 (material denominated R17), two glassy crystalline materials with a crystalline phase Ca2KNa(PO4)2 and in addition a small amorphous portion containing either magnesium potassium phosphate (material denominated GB14) or silica phosphate (material denominated GB9). HBDC was grown on the substrates for 3, 5, 7, 14 and 21 days, counted and probed for various mRNAs and proteins (collagen type I, osteocalcin, osteopontin, osteonectin, alkaline phosphatase and bone sialoprotein). All substrates supported continuous cellular growth for 21 days. At day 21, R17, GB9, TCP and GB14. T2 - 15th International Symposium on Ceramics in Medicine CY - Sydney, NSW, Australia DA - 2002-12-04 PY - 2002 DO - https://doi.org/10.4028/www.scientific.net/KEM.240-242.679 SN - 1013-9826 VL - 240-242 SP - 679 EP - 682 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-1891 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Knabe, C. A1 - Howlett, C. A1 - Markovic, B. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Reif, D. A1 - Zreiqat, H. T1 - The functional expression of human bone derived cells grown on resorbable bioactive glass ceramics T2 - 28th Annual Meeting & Exposition of the Society for Biomaterials CY - Tampa, FL, USA DA - 2002-04-23 PY - 2002 SP - 706 PB - Society for Biomaterials AN - OPUS4-1892 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Gross, U. A1 - Müller-Mai, C. A1 - Voigt, C. A1 - Berger, Georg A1 - Spitzer, Andrea T1 - In vivo test of a high porous rapidly resorbable dicalcium potassium sodium phosphate glass-ceramics T2 - 14th International Symposium on Ceramics in Medicine ; Annual meeting of the International Society for Ceramics in Medicine 2001 CY - Palm Springs, CA, USA DA - 2001-11-14 PY - 2002 SN - 1013-9826 VL - 218-220 SP - 307 EP - 310 PB - Trans Tech Publ. CY - Aedermannsdorf AN - OPUS4-1893 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Gross, U. A1 - Müller-Mai, C. A1 - Knabe, C. A1 - Berger, Georg A1 - Ploska, Ute A1 - Gildenhaar, Renate ED - Vincenzini, P. T1 - Animal experiments with biomaterials for direct bone contact which possess in comparison to TCP and HA products higher or lower solubility T2 - 10th International Ceramics Congress ; 3rd Forum on New Materials ; 10th CIMTEC 2002 CY - Florence, Italy DA - 2002-07-14 PY - 2003 PB - Techna CY - Faenza AN - OPUS4-1894 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Bioresorbierbarkeit anorganischer Knochenersatzwerkstoffe T2 - Vorlesung im Rahmen der RIngvorlesung 0334 VL 113 "Aufbau und Eigenschaften moderner Biomaterialien", Technische Universität Berlin/Humboldt Universität zu Berlin, Charité/Freie Universität Berlin CY - Berlin, Germany DA - 2002-01-28 PY - 2002 AN - OPUS4-1895 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Offenporige Keramiken für den Knochenersatz T2 - Vorlesung im Rahmen der Ringvorlesung 0334 VL 113 "Aufbau und Eigenschaften moderner Biomaterialien" (Technische Universität Berlin/Humboldt Universität zu Berlin, Charité/Freie Universität Berlin) CY - Berlin, Deutschland DA - 2002-01-28 PY - 2002 AN - OPUS4-1896 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Calciumhaltiger resorbierbarer Knochenersatz - Beginn und aktuelle Entwicklungen T2 - 1. Workshop "Keramische Biomaterialien" CY - Freiberg, Deutschland DA - 2002-06-14 PY - 2002 AN - OPUS4-1897 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Knabe, C. A1 - Howlett, C.R. A1 - Markovic, B. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Zreiqat, H. T1 - Beeinflussung der Gen- und Proteinexpression von Osteoblasten durch bioaktive resorbierbare Glaskeramiken T2 - Bericht der 2. gemeinsamen Jahrestagung der Deutschen Gesellschaft für Implantologie im Zahn-, Mund- und Kieferbereich, der Österreichischen Gesellschaft für orale Chirurgie und Implantologie sowie der Schweizerischen Gesellschaft für orale Implantologie CY - München, Deutschland DA - 2002-12-05 PY - 2002 AN - OPUS4-1898 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Berger, Georg T1 - Determination of the internal surface of spongiosa-like ceramic scaffolds using light microscopy and X-ray refraction technique T2 - 15th International Symposium on Ceramics in Medicine (Bioceramics 15) CY - Sydney, Australia DA - 2002-12-04 PY - 2002 AN - OPUS4-1899 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Jäger, Christian A1 - Pauli, Jutta A1 - Berger, Georg A1 - Spitzer, Andrea T1 - Entwicklung neuartiger Knochenersatzwerkstoffe und strukturelle Charakterisierung mittels der 31P-NMR-Spektroskopie T2 - Tagung "Tag der Chemie" CY - Berlin, Deutschland DA - 2002-12-04 PY - 2002 AN - OPUS4-1900 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Driessens, F. C. M. A1 - De Maeyer, E. A. P. A1 - Fernández, E. A1 - Boltong, M. G. A1 - Berger, Georg A1 - Verbeeck, R. M. H. A1 - Ginebra, M. P. A1 - Planell, J. A. T1 - Amorphous calcium phosphate cements and their transformation into calcium deficient hydroxyapatite KW - Zement KW - Kalzium-Phosphat PY - 1996 VL - 9 SP - 231 EP - 234 AN - OPUS4-704 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Berger, Georg T1 - Vielseitige Biokeramik - Betrachtungen zum gegenwärtigen Stand der Anwendung und zu aktuellen Forschungszielen in der Biokeramik KW - Biokeramik PY - 1999 SN - 1436-3704 IS - 3 SP - 10 EP - 11 PB - Schlüter CY - Hannover AN - OPUS4-756 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Knabe, C. A1 - Howlett, C. A1 - Markovic, B. A1 - Klar, F. A1 - Zreiqat, H. T1 - The Effect of Different Dental Titanium and Calcium Phosphate Implant Surfaces on the Expression of Bone-Related Genes and Proteins in vitro T2 - 6th World Biomaterials Congress CY - Kamuela, Big Island, HI, USA DA - 2000-05-15 KW - Dental Implant Surfaces PY - 2000 VL - 1 SP - 238 PB - Society for Biomaterials CY - Minneapolis, Minn. AN - OPUS4-869 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Knabe, C. A1 - Howlett, C. A1 - Markovic, B. A1 - Reif, D. A1 - Zreiqat, H. T1 - The Functional Expression of Human Bone Derived Cells Grown on Rapidly Resorbable Calcium Phosphate Ceramics T2 - 6th World Biomaterials Congress CY - Kamuela, Big Island, HI, USA DA - 2000-05-15 KW - Calcium Phosphate Ceramics PY - 2000 SP - 970 PB - Society for Biomaterials CY - Minneapolis, Minn. AN - OPUS4-870 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Berger, Georg A1 - Müller-Mai, C. A1 - Voigt, C. A1 - Gross, U. ED - Wise, D. L. T1 - Bone development and bone structure depend on surface roughness and structure of metalic implants KW - Bone Development KW - Surface Structure PY - 2000 SN - 0-8247-0318-9 SP - 457 EP - 481 PB - Dekker CY - New York AN - OPUS4-878 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -