TY - GEN A1 - Reiche, I. A1 - Berger, Achim A1 - Duval, A. A1 - Görner, Wolf A1 - Guicharnaud, H. A1 - Merchel, Silke A1 - Radtke, Martin A1 - Riederer, J. A1 - Riesemeier, Heinrich A1 - Roth, M. ED - Röhrs, S. T1 - Auf den Spuren Albrecht Dürers - Zerstörungsfreie Untersuchung von Silberstiftzeichnungen mittels Mikro-PIXE und Synchrotron-induzierter Mikro-RFA T2 - Jahrestagung 2003 im Ethnologischen Museum Berlin-Dahlem CY - Berlin, Deutschland DA - 2003-03-12 PY - 2003 SN - 3-00-014223-1 SN - 0949-4057 SP - 118 EP - 120 CY - [Frankfurt am Main] AN - OPUS4-2356 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Reiche, I. A1 - Berger, Achim A1 - Duval, A. A1 - Görner, Wolf A1 - Guicharnaud, H. A1 - Merchel, Silke A1 - Radtke, Martin A1 - Riederer, J. A1 - Riesemeier, Heinrich A1 - Roth, M. ED - Marabelli, M. ED - Tabaso, M. T1 - Spatially resolved SR-XRF analyses of complex drawings of the Holbein family T2 - 8th International Conference on "Non-Destructive Investigations and Microanalysis for the Diagnostics and Conservation of the Cultural and Environmental Heritage" CY - Lecce, Italy DA - 2005-05-15 KW - X-ray spectrometry KW - XRF KW - Röntgenfluoreszenzanalyse KW - RFA KW - Silverpoint drawing KW - Silberstiftzeichnung PY - 2005 SP - 7 pages PB - Italian Society of Non Destructive Testing CY - Lecce AN - OPUS4-7677 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Merchel, Silke A1 - Berger, Achim A1 - Görner, Wolf A1 - Radtke, Martin A1 - Riesemeier, Heinrich A1 - Reiche, I. A1 - Riederer, J. A1 - Duval, A. A1 - Guicharnaud, H. T1 - Non-Destructive Investigations of Dürer's Silver Point Drawings by Pixe and SY-XRF T2 - 7th International Conference on Non-destructive testing and Microanalysis for the Diagnostics and Conservation of the Cultural and Environmental Heritage ; art 2002 CY - Antwerp, Belgium DA - 2002-06-02 PY - 2002 UR - http://srs.dl.ac.uk/arch/publications/reiche/reiche_fullcorr.pdf SP - 82 AN - OPUS4-1400 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Reiche, I. A1 - Berger, Achim A1 - Duval, A. A1 - Görner, Wolf A1 - Guicharnaud, H. A1 - Merchel, Silke A1 - Radtke, Martin A1 - Riederer, J. A1 - Riesemeier, Heinrich A1 - Roth, M. ED - Denker, A. ED - Adriaens, A. ED - Dowsett, M. ED - Giumlia-Mair, A. T1 - Synchrotron radiation and protons on the traces of famous artists - Non-destructive analyses of silverpoint drawings by Albrecht Dürer KW - X-ray spectrometry KW - XRF KW - Röntgenfluoreszenzanalyse KW - RFA KW - Silverpoint drawing KW - Silberstiftzeichnung PY - 2006 SN - 3-8167-7178-5 SP - 91 EP - 101 PB - Fraunhofer-IRB-Verl. CY - Stuttgart AN - OPUS4-14190 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Reiche, I. A1 - Berger, Achim A1 - Duval, A. A1 - Görner, Wolf A1 - Guicharnaud, H. A1 - Merchel, Silke A1 - Radtke, Martin A1 - Riederer, J. A1 - Riesemeier, Heinrich T1 - Traces of Albrecht Dürer: Non-destructive analyses of Renaissance silverpoint drawings KW - Nuclear industry KW - Nuclear medicine PY - 2004 SN - 92-0-114703-1 SN - 0074-1876 IS - 1181 SP - 138 EP - 142 PB - IAEA CY - Vienna AN - OPUS4-5548 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Reiche, I. A1 - Berger, Achim A1 - Bevers, H. A1 - Dupuis, G. A1 - Duval, A. A1 - Görner, Wolf A1 - Guicharnaud, H. A1 - Merchel, Silke A1 - Radtke, Martin A1 - Riederer, J. A1 - Riesemeier, Heinrich A1 - Roth, M. T1 - Spatially resolved SR-XRF analyses of complex drawings by the Holbein family and silverpoint drawings by Rembrandt KW - X-ray spectrometry KW - XRF KW - Röntgenfluoreszenzanalyse KW - RFA KW - Silverpoint drawing KW - Silberstiftzeichnung PY - 2005 UR - http://www.helmholtz-berlin.de/media/media/oea/web/pr_webseite/druckschriften/berichte/bessy/annualreport2004.pdf#page=491 SN - 0179-4159 SP - 491 EP - 493 PB - Berliner Elektronenspeicherring-Gesellschaft für Synchrotronstrahlung CY - Berlin AN - OPUS4-7380 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Reiche, I. A1 - Berger, Achim A1 - Duval, A. A1 - Görner, Wolf A1 - Merchel, Silke A1 - Radtke, Martin A1 - Riederer, J. A1 - Riesemeier, Heinrich T1 - Metallstiftzeichnungen Albrecht Dürers KW - Synchrotron KW - XRF analysis KW - Drawings KW - Archaeometry KW - Röntgenfluoreszenzanalyse (RFA) KW - Zeichnungen KW - Archäometrie KW - Albrecht Dürer PY - 2004 SN - 1563-2628 VL - 5 IS - 2 SP - 30 EP - 38 PB - Foto Text Verl. CY - Stuttgart AN - OPUS4-3570 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - GEN A1 - Merchel, Silke A1 - Berger, Achim A1 - Görner, Wolf A1 - Radtke, Martin A1 - Reinholz, Uwe A1 - Riesemeier, Heinrich A1 - Vogl, Jochen A1 - Frisch, A. A1 - Reiche, I. T1 - Kunst- und Kulturgüter unter "Beschuss" T2 - GDCh-Jahrestagung Chemie 2003 ; Jahrestagung der Fachgruppe Nuklearchemie ; 19. Seminar Aktivierungsanalyse CY - München, Deutschland DA - 2003-10-06 PY - 2003 SN - 3-936028-14-1 N1 - Serientitel: Kurzreferate / GDCh-Jahrestagung Chemie 2003 – Series title: Kurzreferate / GDCh-Jahrestagung Chemie 2003 IS - 5 SP - 68 PB - Gesellschaft Deutscher Chemiker CY - Frankfurt am Main AN - OPUS4-2686 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Winkler, T. A1 - Hoenig, E. A1 - Huber, G. A1 - Janssen, R. A1 - Fritsch, D. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Morlock, M.M. A1 - Schilling, A.F. T1 - Osteoclastic bioresorption of biomaterials: Two- and three-dimensional imaging and quantification N2 - Purpose: Bioresorbable materials have been developed in the hope that the body will replace them with newly formed tissue. The first step of this remodeling process in bone is the bioresorption of the material by osteoclasts. The aim of this study was to analyze osteoclastic resorption of biomaterials in vitro using the commonly used two-dimensional methods of light-microscopy (LM) and scanning electron microscopy (SEM) in comparison with infinite focus microscopy (IFM), a recently developed imaging method allowing for three-dimensional surface analysis. Methods: Human hematopoietic stem cells were cultivated in the presence of the cytokines M-CSF and RANK-L for 4 weeks directly on dentin and a calcium phosphate cement. Osteoclast development was surveyed with standard techniques. After removal of the cells, resorption was characterized and quantified by LM, SEM and IFM. Results: Osteoclast cultures on the biomaterials presented the typical osteoclast-specific markers. On dentin samples LM, SEM as well as IFM allowed for discrimination of resorption. Quantification of the resorbed area showed a linear correlation between the results (LM vs. SEM: r=0.996, p=0.004; SEM vs. IFM: r=0.989, p=0.011; IFM vs. LM: r=0.995). It was not possible to demarcate resorption pits on GB14 using LM or SEM. With IFM, resorption on GB14 could be visualized and quantified two- and three-dimensionally. KW - Biomaterial KW - Three-dimensional KW - IFM KW - Osteoclast KW - Dentin KW - Calcium phosphate PY - 2010 SN - 0391-3988 VL - 33 IS - 4 SP - 198 EP - 203 PB - Wichtig Ed. CY - Milano [u.a.] AN - OPUS4-21621 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Winkler, T. A1 - Hoenig, E. A1 - Gildenhaar, Renate A1 - Berger, Georg A1 - Fritsch, D. A1 - Janssen, R. A1 - Morlock, M.M. A1 - Schilling, A.F. T1 - Volumetric analysis of osteoclastic bioresorption of calcium phosphate ceramics with different solubilities N2 - Commonly, to determine osteoclastic resorption of biomaterials only the resorbed area is measured. The depth of the resorption pit, however, may also be important for the performance of a material. To generate such data we used two calcium phosphate ceramics (Ca10 and Ca2). The solubility of the materials was determined according to DIN EN ISO 10993-14. They were scanned three-dimensionally using infinite focus microscopy and subsequently cultivated for 4 weeks in simulated body fluid without (control) or with human osteoclasts. After this cultivation period osteoclasts number was determined and surface changes were evaluated two- and three-dimensionally. Ca10 and Ca2 showed solubilities of 11.0 ± 0.5 and 23.0 ± 2.2 mg g-1, respectively. Both materials induced a significant increase in osteoclast number. While Ca10 did not show osteoclastic resorption, Ca2 showed an increased pit area and pit volume due to osteoclastic action. This was caused by an increased average pit depth and an increased number of pits, while the average area of single pits did not change significantly. The deduced volumetric osteoclastic resorption rate (vORR) of Ca2 (0.01–0.02 µm3 µm-2 day-1) was lower than the remodelling speed observed in vivo (0.08 µm3 µm-2 day-1), which is in line with the observation that implanted resorbable materials remain in the body longer than originally expected. Determination of volumetric indices of osteoclastic resorption might be valuable in obtaining additional information about cellular resorption of bone substitute materials. This may help facilitate the development of novel materials for bone substitution. KW - Biodegradation KW - Surface analysis KW - Simulated body fluid KW - Osteoclasts KW - Calcium phosphate ceramics PY - 2010 DO - https://doi.org/10.1016/j.actbio.2010.04.015 SN - 1742-7061 VL - 6 IS - 10 SP - 4127 EP - 4135 PB - Elsevier CY - Amsterdam AN - OPUS4-22554 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -