TY - CHAP A1 - Gawlitza, Kornelia A1 - Wan, Wei A1 - Wagner, Sabine A1 - Rurack, Knut ED - Tiwari, Ashutosh ED - Uzun, Lokman T1 - Fluorescent Molecularly Imprinted Polymers N2 - An ideal sensor system is a combination of a selective receptor, an effective transducer, and a sensitive detector. To utilize molecularly imprinted polymers (MIPs) as responsive recognition phases in sensors, the employment of fluorescent molecules or nanoparticles (NPs) that show prominent changes in their spectroscopic properties after binding of the target molecule in the MIP’s cavity is particularly attractive. Such fluorescent MIPs (fMIPs) act through target-induced quenching, enhancement, or spectral shifts of the fluorescence. This contribution introduces different strategies of incorporation of fluorescent dyes, probes, and NPs into fMIPs. In addition, various sensing mechanisms are reviewed, and depending on the application of the sensor, the different deployable formats, their advantages, drawbacks, and impact will be presented and discussed. KW - Dyes KW - Fluorescence KW - Molecular imprinted polymers KW - Quantum dots KW - Sensors PY - 2017 SN - 978-1-119-33629-7 SP - 89 EP - 128 PB - Scrivener Publishing, WILEY CY - Beverly, MA ET - 1 AN - OPUS4-38798 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Wan, Wei A1 - Wagner, Sabine A1 - Rurack, Knut T1 - Fluorescent monomers: "bricks" that make a molecularly imprinted polymer "bright" N2 - Molecularly imprinted polymers (MIPs) are potent and established recognition phases in separation and enrichment applications. Because of their robustness, versatility and format adaptability, they also constitute very promising sensing phases, especially when the active sensing element is directly integrated into the MIP. Fluorescent MIPs incorporating fluorescent monomers are perhaps the best developed and most successful approach here. This article reviews the state of the art in this field, discussing the pros and cons of the use of fluorescent dye and probe derivatives as such monomers, the different molecular interaction forces for template complexation, signalling modes and a variety of related approaches that have been realized over the years, including Förster resonance energy transfer processes, covalent imprinting, postmodification attachment of fluorescent units and conjugated polymers as MIPs; other measurement schemes and sensing chemistries that use MIPs and fluorescence interrogation to solve analytical problems (fluorescent competitive assays, fluorescent analytes, etc.) are not covered here. Throughout the article, photophysical processes are discussed to facilitate understanding of the effects that can occur when one is planning for a fluorescence response to happen in a constrained polymer matrix. The article concludes with a concise assessment of the suitability of the different formats for sensor realization. KW - Chemical sensors KW - Fluorescence KW - Molecularly imprinted polymers KW - Dyes KW - Sol-gel PY - 2016 U6 - https://doi.org/10.1007/s00216-015-9174-4 SN - 1618-2642 SN - 1618-2650 VL - 408 IS - 7 SP - 1753 EP - 1771 PB - Springer CY - Berlin AN - OPUS4-35830 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -