TY - JOUR A1 - Wan, Wei A1 - Biyikal, Mustafa A1 - Wagner, R. A1 - Sellergren, B. A1 - Rurack, Knut T1 - Sensorische Mikropartikel aus einem Silicatkern und einem molekular geprägten Polymer als Schale mit aufleuchtender Fluoreszenz N2 - Und es ward Licht – der Einbau eines auf Harnstoff basierenden Fluoreszenzfarbstoffs in eine mit Anionen geprägte dünne Polymerschale (MIP) auf Silicatmikropartikeln führt zu einem spezifischen und enantioselektiven Aufleuchten der Fluoreszenz in Gegenwart des Zielanalyten. KW - Enantioselektivität KW - Fluoreszenz KW - Kern-Schale-Partikel KW - Molekular geprägte Polymere KW - Sensoren PY - 2013 U6 - https://doi.org/10.1002/ange.201300322 SN - 0044-8249 SN - 0932-2140 SN - 1521-3757 VL - 125 IS - 27 SP - 7161 EP - 7165 PB - Wiley-VCH CY - Weinheim AN - OPUS4-28739 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Wan, Wei A1 - Biyikal, Mustafa A1 - Wagner, R. A1 - Sellergren, B. A1 - Rurack, Knut T1 - Fluorescent sensorymicroparticles that 'light-up' consisting of a silica core and a molecularly imprinted polymer (MIP) shell N2 - From darkness came light: Incorporation of urea-based fluorescent dyes in an anion-imprinted thin polymer shell coated onto silica microparticles leads to a unique and highly enantioselective fluorescent 'light-up' response to analytes (see scheme, MIP molecularly imprinted polymer). KW - Core–shell particles KW - Enantioselectivity KW - Fluorescence KW - Molecularly imprinted polymers KW - Sensors PY - 2013 U6 - https://doi.org/10.1002/anie.201300322 SN - 1433-7851 SN - 1521-3773 SN - 0570-0833 VL - 52 IS - 27 SP - 7023 EP - 7027 PB - Wiley-VCH CY - Weinheim AN - OPUS4-28740 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wan, Wei A1 - Rurack, Knut A1 - Biyikal, Mustafa A1 - Wagner, R. A1 - Sellergren, B. T1 - Direct Anion Sensing with Amplified Flourescence Using Moleculary Imprinted Core-Shell Nanoparticles T2 - 8. Deutsches BioSensor Symposium CY - Wildau, Germany DA - 2013-03-10 PY - 2013 AN - OPUS4-27846 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wan, Wei A1 - Rurack, Knut A1 - Biyikal, Mustafa A1 - Panne, Ulrich A1 - Wagner, R. A1 - Sellergren, B. T1 - Flourescent MIP sensors: broadening the scope of molecularly imprinted polymers T2 - ANAKON 2013 CY - Essen, Germany DA - 2013-03-04 PY - 2013 AN - OPUS4-27849 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wan, Wei A1 - Biyikal, Mustafa A1 - Rurack, Knut A1 - Wagner, Ricarda A1 - Sellergren, B. T1 - Molecularly imprinted polymers as sensory materials for the selective detection of carboxylates via fluorescence enhancement T2 - 4th Graduate Student Symposium on Molecular Imprinting CY - London, England DA - 2011-09-28 PY - 2011 AN - OPUS4-24698 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Wagner, R. A1 - Wan, Wei A1 - Biyikal, Mustafa A1 - Benito-Pena, E. A1 - Moreno-Bondi, M.C. A1 - Lazraq, I. A1 - Rurack, Knut A1 - Sellergren, B. T1 - Synthesis, spectroscopic, and analyte-responsive behavior of a polymerizable naphthalimide-based carboxylate probe and molecularly imprinted polymers prepared thereof N2 - A naphthalimide-based fluorescent indicator monomer 1 for the integration into chromo- and fluorogenic molecularly imprinted polymers (MIPs) was synthesized and characterized. The monomer was equipped with a urea binding site to respond to carboxylate-containing guests with absorption and fluorescence changes, namely a bathochromic shift in absorption and fluorescence quenching. Detailed spectroscopic analyses of the title compound and various models revealed the signaling mechanism. Titration studies employing benzoate and Z-ʟ-phenylalanine (Z-ʟ-Phe) suggest that indicator monomers such as the title compound undergo a mixture of deprotonation and complex formation in the presence of benzoate but yield hydrogen-bonded complexes, which are desirable for the molecular imprinting process, with weakly basic guests like Z-ʟ-Phe. Compound 1 could be successfully employed in the synthesis of monolithic and thin-film MIPs against Z-ʟ-Phe, Z-L-glutamic acid, and penicillin G. Chromatographic assessment of the selectivity features of the monoliths revealed enantioselective discrimination and clear imprinting effects. Immobilized on glass coverslips, the thin-film MIPs of 1 displayed a clear signaling behavior with a pronounced enantioselective fluorescence quenching dependence and a promising discrimination against cross-analytes. KW - Aminosäuren KW - Enantioselektivität KW - Fluoreszenz KW - Molekular geprägte polymere KW - Sensorfilme PY - 2013 U6 - https://doi.org/10.1021/jo3019522 SN - 0022-3263 SN - 1520-6904 VL - 78 IS - 4 SP - 1377 EP - 1389 PB - American Chemical Society CY - Washington, DC AN - OPUS4-27741 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wan, Wei A1 - Biyikal, Mustafa A1 - Rurack, Knut A1 - Wagner, R. A1 - Sellergren, B. T1 - Moleculary imprinted polymer as sensory materials for the selective detection of carboxylates via fluorescence enhancement T2 - 7th INTERNATIONAL CONFERENCE on Molecularly Imprinted Polymers - Science and Technology CY - Paris, France DA - 2012-08-27 PY - 2012 AN - OPUS4-26851 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wan, Wei A1 - Biyikal, Mustafa A1 - Wagner, R. A1 - Sellergren, B. A1 - Rurack, Knut T1 - Enantioselective fluorescence response of molecularly imprinted polymers (MIPs) toward carbobenzyloxy- (Cbz) protected amino acids N2 - Integration of a polymerisable fluorescent urea-nitrobenzoxadiazole monomer 1 into a few-nanometre thin molecularly imprinted polymer (MIP) shell coated onto a 300 nm silica core with the tetrabutylammonium salt of N-carbobenzyloxy-L-phenylalanine (Cbz- or Z-ʟ-Phe) as the imprinted template yields core/shell MIP nanoparticles that respond to the designated analyte with a strong fluorescence increase in the visible spectral range. The system shows promising imprinting and enantioselectivity factors of 3.6 and 1.9 when benzylmethylacrylate (BMA) is used as co-monomer and ethylene glycol dimethacrylate (EDMA) as cross-linker. A second, naphthalimide-based fluorescent urea 2 is employed in the preparation of MIP thin-films and monolithic polymers for separation techniques. Spectroscopic and chromatographic studies of the MIPs with the analytes Z-ʟ-Phe, Z-ʟ-glutamic acid (Z-ʟ-Glu) and penicilin G (PenG) revealed the (enantio)selective discrimination behaviour of these materials. T2 - 11. Dresdner Sensor Symposium 2013 CY - Dresden, Germany DA - 09.12.2013 KW - Enantioselectivity KW - Molecular imprinting KW - Fluorescence KW - Core-shell nanoparticles KW - Chromatography PY - 2013 SN - 978-3-9813484-5-3 U6 - https://doi.org/10.5162/11dss2013/3.2 SP - 53 EP - 58 CY - Wunstorf AN - OPUS4-29818 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Climent Terol, Estela A1 - Wan, Wei A1 - Rurack, Knut T1 - Toward Label-Free Optical Multiplexing of Analytes in Indicator Release Lateral Flow Assays via Detection Zones Containing Tailored Capture Materials N2 - The use of macromolecules and materials immobilized in the detection zone of test strips for indicator capture and focusing in label-free lateral flow assays (LFAs) is described, with emphasis on its future use in low number multiplexing. Several materials such as polyelectrolytes, functionalized mesoporous silica micro- and nanoparticles, chemically modified cellulose or glass fibre (GF) membranes and molecularly imprinted polymer gels coated onto membranes were studied in model assays, before the most promising materials were combined with antibody-gated indicator delivering (gAID) sensor materials. Cellulose, nitrocellulose and GF membranes were used as supports and highly fluorescent dyes of different charge states as model indicators. Combination of the best performing capture materials with gAID systems made it possible to distinctly increase the sensitivity and reduce the measurement uncertainty in the LFA testing of pentaerythritol tetranitrate (PETN) in aqueous samples. In addition, dual-plexing of PETN and 2,4,6-trinitrotoluene (TNT) was realized on a single test strip containing two dedicated capture zones. KW - Rapid tests KW - Vor-Ort-Analytik KW - Multiplexing KW - Teststreifen KW - Molecularly imprinted polymers PY - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:b43-557873 VL - 2 IS - 4 SP - 1 EP - 10 PB - Wiley-VCH CY - Weinheim AN - OPUS4-55787 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wan, Wei A1 - Apel, Jenny A1 - Rurack, Knut A1 - Descalzo, Ana B. T1 - Assessing the FRET Acceptor Potential of Various BODIPY Dyes for Europium as the FRET Donor T2 - International Bunsen Discussion Meeting on Förster Resonance Energy Transfer in Life Sciences CY - Göttingen, Germany DA - 2011-03-27 PY - 2011 AN - OPUS4-23937 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -