TY - JOUR A1 - Gawlitza, Kornelia T1 - Wieviel Schmutz ist rein? Über das Arbeiten im Reinraum N2 - Um verlässliche Methoden für die medizinische Diagnostik und Umweltanalytik zu entwickeln sowie Zellen zu kultivieren, ist staub- bzw. keimfreies Arbeiten in einem Reinraum erforderlich. Aber was ist ein Reinraum? Viele stellen sich hier sterile Räume, keine Fenster und Personen in weißen Anzügen und Schutzmaske vor. Hier können die Besucher einen Blick hinter die Kulissen werfen und erfahren, was die Eigenschaften und Bedingungen eines Reinraumes sind und welche Anforderungen an die dort Beschäftigten gestellt werden. KW - Reinraum PY - 2017 UR - http://www.aktuelle-wochenschau.de/main-navi/aktuelle-wochenschau-2017/kw49-wieviel-schmutz-ist-rein-ueber-das-arbeiten-im-reinraum.html SP - 1 EP - 2 AN - OPUS4-43355 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Climent Terol, Estela A1 - Biyikal, Mustafa A1 - Gawlitza, Kornelia A1 - Dropa, T. A1 - Urban, M. A1 - Costero, A. M. A1 - Martínez-Mánez, Ramon A1 - Rurack, Knut T1 - Determination of the chemical warfare agents Sarin, Soman and Tabun in natural waters employing fluorescent hybrid silica materials N2 - A novel mesoporous silica material containing boron–dipyrromethene (BODIPY) moieties (I) is employed for the detection of nerve agent simulants (NASs) and the organophosphate nerve or chemical warfare agents (CWAs) Sarin (GB), Soman (GD), and Tabun (GA) in aqueous environments. The reactive BODIPY dye with an optimum positioned hydroxyl group undergoes acylation reactions with phosph(on)ate substrates, yielding a bicyclic ring. Due to aggregation of the dyes in water, the sensitivity of the free dye in solution is very low. Only after immobilization of the BODIPY moieties into the silica substrates is aggregation inhibited and a sensitive determination of the NASs diethyl cyanophosphonate (DCNP), diethyl chlorophosphate (DCP) and diisopropyl fluorophosphate (DFP) possible. The signaling mode is a strong quenching of the fluorescence, reaching LODs in the pM range. The best performing hybrid material was singled out from a library of hybrid silicas varying in morphology and surface functionalization. The response to actual CWAs such as GB, GD, and GA has also been tested, offering similar behavior as for the simulants. The proposed reaction mechanism has been verified by investigation of other model materials, containing for instance BODIPY moieties without an optimum hydroxyl group (III) or a BODIPY dye with an all-aliphatic counterpart (IV). The latter can only form a monocyclic reaction product, showing much less reactivity as I. Assays with other possible competitors have been additionally carried out, showing favorably low cross-reactivities. Finally, the determination of NASs in several natural waters has been demonstrated. KW - Nerve agent simulants KW - Mesoporous silica materials KW - Fluorescence detection PY - 2017 UR - http://www.sciencedirect.com/science/article/pii/S0925400517303428 U6 - https://doi.org/10.1016/j.snb.2017.02.115 SN - 0925-4005 VL - 246 SP - 1056 EP - 1065 PB - Elsevier B.V. AN - OPUS4-39739 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Ritter, B. A1 - Haida, P. A1 - Fink, F. A1 - Krahl, T. A1 - Gawlitza, Kornelia A1 - Rurack, Knut A1 - Scholz, G. A1 - Kemnitz, E. T1 - Novel and easy access to highly luminescent Eu and Tb doped ultra-small CaF2, SrF2 and BaF2 nanoparticles – structure and luminescence N2 - A universal fast and easy access at room temperature to transparent sols of nanoscopic Eu3+ and Tb3+ doped CaF2, SrF2 and BaF2 particles via the fluorolytic sol–gel synthesis route is presented. Monodisperse quasi-spherical nanoparticles with sizes of 3–20 nm are obtained with up to 40% rare earth doping showing red or green luminescence. In the beginning luminescence quenching effects are only observed for the highest content, which demonstrates the unique and outstanding properties of these materials. From CaF2:Eu10 via SrF2:Eu10 to BaF2:Eu10 a steady increase of the luminescence intensity and lifetime occurs by a factor of ≈2; the photoluminescence quantum yield increases by 29 to 35% due to the lower phonon energy of the matrix. The fast formation process of the particles within fractions of seconds is clearly visualized by exploiting appropriate luminescence processes during the synthesis. Multiply doped particles are also available by this method. Fine tuning of the luminescence properties is achieved by variation of the Ca-to-Sr ratio. Co-doping with Ce3+ and Tb3+ results in a huge increase (>50 times) of the green luminescence intensity due to energy transfer Ce3+ → Tb3+. In this case, the luminescence intensity is higher for CaF2 than for SrF2, due to a lower spatial distance of the rare earth ions. KW - Luminescence materials KW - Alkaline earth metal fluorides KW - Fluorolytic sol–gel synthesis PY - 2017 U6 - https://doi.org/10.1039/C6DT04711D VL - 46 IS - 9 SP - 2925 EP - 2936 PB - Royal Society of Chemistry AN - OPUS4-39286 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -