TY - CONF A1 - Bell, Jérémy A1 - Ashokkumar, Pichandi A1 - Buurman, Merwe A1 - Rurack, Knut T1 - Sugar detection in sodas utilizing a fluorescent microfluidics sensor N2 - Because of the globally increasing prevalence of diabetes, the need for accurate, efficient and at best miniaturized automated analytical systems for sugar detection is still urgent. The development of molecular probes for sugar based on boronic acid receptors1 offers an excellent alternative to the kinetically slow enzyme-based sugar sensors. Moreover, by coupling such chelating units with rhodamines, fluorescein or BODIPY moieties, colorimetric and/or highly fluorescent sugar sensing schemes can be obtained.2 In this work, a boronic acid-functionalized BODIPY probe is described; it binds selectivity to fructose's adjacent diols to form cyclic boronate esters in partially aqueous solutions, with a broad pH range compatibility and a sensitivity in the micromolar range. To enhance the applicability of the fluorometric test in the sense described above, integration with a microfluidic sensor was achieved. The miniaturization of chemical analysis systems yields many functional and economical benefits such as low cost, ease of use, high stability and good portability. With similar selectivity and sensitivity, fructose was detected by fluorescence in real time in the chip, and an assay for the straightforward detection of sugar in sodas was achieved. T2 - IMA 2015 CY - Kalamata, Grece DA - 2015-09-20 PY - 2015 AN - OPUS4-34776 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - JOUR A1 - Lempke, L. A1 - Fischer, Tobias A1 - Bell, Jérémy A1 - Kraus, Werner A1 - Rurack, Knut A1 - Krause, N. T1 - Gold-catalyzed allene cycloisomerization for pyrrole synthesis: towards highly fluorinated BODIPY dyes N2 - A novel synthetic strategy toward highly fluorinated BODIPY dyes with exceptional photostabilities relying on sustainable gold catalysis has been developed. A key to the tailored pyrrole precursors is the gold catalysis performed in ionic liquids as the reaction medium, allowing a facile recycling of the catalysts. The dyes prepared are well-matching with the spectral windows of popular rhodamine dyes and possess high brightness while showing a distinctly higher photostability than the rhodamines especially in aprotic solvents. KW - Gold-Katalyse KW - BODIPY-Farbstoffe KW - Photostabilität KW - Fluor-Substitution KW - Fluoreszenz PY - 2015 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-344692 DO - https://doi.org/10.1039/c4ob02671c SN - 1477-0520 SN - 1477-0539 VL - 13 IS - 12 SP - 3787 EP - 3791 PB - RSC CY - Cambridge AN - OPUS4-34469 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Bell, Jérémy A1 - Climent Terol, Estela A1 - Buurman, Merwe A1 - Rurack, Knut T1 - Droplet-assisted liquid-liquid extraction of fluorescent cargo released from gated sensory nanoparticles in a microfluidic system T2 - Central European Conference on Photochemistry CECP 2014 CY - Bad Hofgastein, Austria DA - 2014-02-09 PY - 2014 N1 - Geburtsname von Buurman, Merwe: Albrecht, M. - Birth name of Buurman, Merwe: Albrecht, M. AN - OPUS4-31308 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Bell, Jérémy A1 - Ashokkumar, Pichandi A1 - Buurman, Merwe A1 - Rurack, Knut T1 - Microfluidic sensor for fructose detection using a BODIPY probe T2 - MSMLG 2014 Conference CY - Shanghai, China DA - 2014-11-09 PY - 2014 AN - OPUS4-32078 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -