TY - JOUR A1 - Ashokkumar, Pichandi A1 - Weißhoff, Hardy A1 - Kraus, Werner A1 - Rurack, Knut T1 - Test-strip-based fluorometric detection of fluoride in aqueous media with a BODIPY-linked hydrogen-bonding receptor JF - Angewandte Chemie / International Edition N2 - The measurement of biologically relevant anions, such as fluoride, is an important task in analytical chemistry, in particular, for dental health and osteoporosis. Although a large number of fluoride probes are known, the applicability under relevant conditions is limited to a few examples. To improve this situation, BODIPY-amidothiourea dyes with varying hydrogen-bond donating strengths were developed, the most H-acidic of which (1 c) could detect F- from an inorganic source (NaF) in 50?% aqueous solution (DMSO/water 1:1, v/v) with 0.01 ppm sensitivity through selective fluorescence quenching by a photoinduced electron-transfer (PET) process. Use of the probe and a reference dye with a test-strip assay and a portable and rapidly recording lateral-flow fluorescence reader made determination of F- in neat aqueous solutions, such as spiked water samples and toothpaste extracts, possible in a self-referenced manner, achieving a detection limit of 0.2 ppm. KW - Amidothiourea KW - Fluorescent probes KW - Fluoride KW - Hydrogen bonds KW - Photoinduced electron transfer PY - 2014 DO - https://doi.org/10.1002/anie.201307848 SN - 1433-7851 SN - 1521-3773 SN - 0570-0833 VL - 53 IS - 8 SP - 2225 EP - 2229 PB - Wiley-VCH CY - Weinheim AN - OPUS4-31936 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -