TY - CONF A1 - Recknagel, Sebastian T1 - The digital reference material document - how to get standards into instruments N2 - Activities of BAm on the transfer of paper-based RM-certificates into machine readable XML-documents, based on the digital calibration certificate are described and highlighted with examples T2 - 2026 European Chemistry Meeting - Jernkontoret TO 45 CY - Stockholm, Sweden DA - 18.03.2026 KW - Reference material KW - Digital reference material document PY - 2026 AN - OPUS4-65737 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - How to get it right with photoluminescence measurements in the UV/VIS/NIR N2 - Optical measurements of transparent solutions of organic dyes and semiconductor quantum dots and scattering materials such as luminescent nanocomposites and microparticles and phosphors dispersed in liquid and solid matrices play an important role in energy conversion, solid-state lighting, medical diagnostics, and security barcoding. A key performance parameter is the photoluminescence quantum yield QY, i.e., the number of emitted per number of absorbed photons. QY of transparent luminophore solutions can be obtained relative to a fluorescence QY standard of known QY. Such relative QY measurements require a calibrated spectrofluorometer. Here, we address typical sources of uncertainty for luminescence measurements and relative and absolute QY measurements from the instrument and material side and provide recommendations to circumvent or at least minimize them for transparent and scattering samples in the UV/vis/NIR/SWIR. T2 - Workshop "Photoluminescence Spectroscopy and its application in Materials Research" CY - Vienna, Austria DA - 19.02.2026 KW - Quality assurance KW - Reference material KW - Fluorescence KW - Dye KW - Traceability KW - Metrology KW - Calibration KW - Reference data KW - Reference product KW - Digital certificate KW - NIR KW - Instrument performance validation PY - 2026 AN - OPUS4-65575 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Molecular and nanoscale emitters photophysics , photoluminescence quantum yields, and surface chemistry N2 - Inorganic nanocrystals such as spectrally shifting lanthanide-based nanoparticles (LnNCs) like NaYF4: Yb, Er and semiconductor quantum dots, organic and inorganic particles stained with sensor molecules, and organic dyes showing aggregation-induced emission are meanwhile broadly applied in the life and material sciences. The identification of optimum particle architectures and molecular structures for photonic applications requires quantitative spectroscopic studies and methods to control and analyse particle surface chemistry. In the following, photoluminescence studies of different emitter classes are presented, thereby addressing the measurement of particle brightness and photoluminescence quantum yields in different spectral windows parameters required for an in-depth mechanistic understanding. In addition, examples for the quantification of surface functional groups on nanomaterials with optical spectroscopy are given. T2 - GdCH Kolloquium CY - Düsseldorf, Germany DA - 11.11.2025 KW - Dye KW - Fluorescence KW - Quantum yield KW - Lifetime KW - Sensor materials KW - Temperature KW - Cr(III) complex KW - Nano KW - Particle KW - Silica KW - Polymer KW - Metrology KW - Quality assurance KW - Reference material KW - Surface chemistry KW - Size KW - Shape KW - Particle number concentration KW - Method KW - Optical assay KW - qNMR KW - Validation KW - Potentiometry KW - XPS PY - 2025 AN - OPUS4-64728 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Quantifying the total and accessible amount of surface functionalities and ligands on nano-materials: Overview and recommended methods N2 - Engineered nanoparticles (NPs) with various chemical compositions and surface functionalities are routinely fabricated for industrial applications such as medical diagnostics, drug delivery, sensing, catalysis, energy conversion and storage, opto-electronics, and information storage. NP function, interaction with biological species, and environmental fate are largely determined by surface functionalities. This calls for reliable, reproducible, and standardized surface characterization methods, which are vital for quality control of NPs, and mandatory to meet increasing concerns regarding their safety. Validated and standardized workflows for surface analysis are also increasingly requested by industry, international standardization organizations, regulatory agencies, and policymakers. To establish comparable measurements of surface functionalities across different labs and ease instrument performance validation, reference test materials and reference materials of known surface chemistry as well as reference data are needed. In the following, different methods for determining surface functionalities on ligand-stabilized core and core/shell NPs include advanced techniques are presented and discussed regarding method-inherent advantages and limitations. Special emphasis is dedicated to traceable quantitative nuclear magnetic resonance (qNMR), X-ray electron spectroscopy (XPS) and time of flight secondary ion mass spectrometry (ToF-SIMS), and simpler optical and electrochemical methods. T2 - LNE Workshop CY - Paris, France DA - 04.11.2025 KW - Quality assurance KW - Fluorescence KW - Nano KW - Particle KW - Synthesis KW - Characterization KW - Advanced material KW - Surface KW - Standardization KW - Reference material KW - Functional group KW - Quantification KW - Coating KW - Automation KW - Potentiometry KW - Method KW - Validation KW - Optical assay KW - Fluram KW - Fluorescamine KW - qNMR KW - Comparison KW - ILC PY - 2025 AN - OPUS4-64726 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - The emp project smurfnano – Standardizing the quantification of surface functionalities, ligands, and coatings on nanomaterials N2 - For industrial applications such as medical diagnostics, drug delivery, sensing, catalysis, energy conversion and storage, opto-electronics, and information storage, meanwhile engineered nanoparticles (NPs) with various chemical compositions and surface functionalities are routinely fabricated. NP function, interaction with biological species, and environmental fate are largely determined by surface functionalities. Reliable, reproducible, and standardized surface characterization methods are therefore vital for quality control of NPs, and mandatory to meet increasing concerns regarding their safety. Also, industry, international standardization organizations, regulatory agencies, and policymakers need validated and standardized measurement methods and reference materials. These needs are addressed by the recently started European metrology project SMURFnano involving 12 partners from different National Metrology Institutes, designated institutes, and research institutes, two university groups as well as one large company and one SME producing NPs. This project as well as first results derived from the development of test and reference materials with a well characterized surface chemistry and ongoing interlaboratory comparisons will be presented. T2 - LNE Workshop CY - Paris, France DA - 04.11.2025 KW - Quality assurance KW - Fluorescence KW - Nano KW - Particle KW - Synthesis KW - Characterization KW - Advanced material KW - Surface KW - Standardization KW - Reference material KW - Functional group KW - Quantification KW - Coating KW - Automation KW - Potentiometry KW - Method KW - Validation KW - Optical assay KW - Fluram KW - qNMR KW - Comparison KW - ILC PY - 2025 AN - OPUS4-64725 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Recknagel, Sebastian T1 - Production of reference materials - not only for batteries N2 - The presentation describes the basic procedure used by BAM to produce certified reference materials. In particular, BAM's reference material activities in the field of lithium batteries are discussed. Following the first NMC 111 reference material, which is already commercially available, further materials are in production, including black masses and lithium carbonate. T2 - Rigaku Battery Forum 2025 CY - Neu-Isenburg, Germany DA - 24.06.2025 KW - Reference material KW - Li-battery KW - Cathode material PY - 2025 AN - OPUS4-64374 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Reliable measurements of the photoluminescence quantum yield of transparent and scattering luminophores N2 - Optical measurements of transparent solutions of organic dyes and semiconductor quantum dots and scattering materials such as luminescent nanocomposites and microparticles and phosphors dispersed in liquid and solid matrices play an important role in energy conversion, solid-state lighting, medical diagnostics, and security barcoding. A key performance parameter is the photoluminescence quantum yield QY, i.e., the number of emitted per number of absorbed photons. QY of transparent luminophore solutions can be obtained relative to a fluorescence QY standard of known QY.[1] Meanwhile, a first set of certified fluorescence QY standards is available.[2] Such relative QY measurements require a calibrated spectrofluorometer.[1,3] For determining QY of scattering liquid and solid samples, absolute measurements of QY with a calibrated integrating sphere setup are mandatory.[1,4,5] However, scattering QY standards are not available and uncertainties of such measurements have not yet been assessed in interlaboratory comparisons (ILCs). To determine typical sources of uncertainty of absolute QY measurements, we assessed the influence of the measurement geometry and the optical properties of the blank for determining the number of incident photons absorbed by the sample in an ILC using commercial integrating sphere setups and a custom-designed integrating sphere setup. Samples examined included transparent and scattering dye solutions, solid phosphors such as YAG:Ce optoceramics used as LED converter material, and polymer films stained with different amounts of phosphor microparticles. Matching QY values could be obtained for transparent dye solutions and scattering dispersions with a blank with scattering properties closely matching those of the sample, while QY measurements of optoceramic samples with different blanks revealed substantial differences of more than 20 %. Based on our data, we recommend non-absorbing blank materials with a high reflectivity (>95 %) such as a 2 mm-thick PTFE target placed on the sample holder as blanks. T2 - eMRS 2025 Fall Meeting CY - Warsaw, Poland DA - 15.09.2025 KW - Quality assurance KW - Fluorescence KW - Nano KW - Particle KW - Advanced material KW - Synthesis KW - Characterization KW - Fluorescence quantum yield KW - Phosphor KW - Absolute KW - Integrating sphere spectroscopy KW - Dye KW - Standardization KW - Reference material KW - Interlaboratory comparison KW - Uncertainty PY - 2025 AN - OPUS4-64184 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Quantifying functional groups and coatings on nanoobjects N2 - Engineered nanomaterials (NM) of different size, shape, chemical composition, and surface chemistry are increasingly used for many key technologies of the 21st century and consumer products. This includes polymer and silica or silica-coated nanoparticles (NP) with covalently bound surface groups, semiconductor quantum dots (QD), metal and metal oxide NP, and lanthanide NP with coordinatively or electrostatically bound ligands, as well as surface-coated nanostructures like micellar encapsulated NP. Decisive for most applications of NMs are their specific surface properties, which are largely determined by the chemical nature and amounts of ligands and functional groups (FGs) on the NM surface. The surface chemistry can strongly affect the physicochemical properties of NM, their charge, hydrophilicity/hydrophobicity, reactivity, function, stability, and processability and thereby their impact on human health and environment. Knowledge of NM surface chemistry plays an important role for NM functionality and performance in (bio)applications and the fate, exposure, dissolution, transformation, and accumulation of NM, and thus, the potential risks for human health and the environment. This highlights the importance of reliable, validated, and eventually standardized analytical methods for analyzing and quantifying NM surface chemistry for process and quality control of NM production, safe use of NMs, design of novel NM, and sustainable concepts for NM fabrication.[1-3] In this context, interlaboratory comparisons (ILCs) are needed to assess method reliability and reference materials with known surface chemistries for establishing surface analytical methods and their performance validation.[2,4] Also, to respond to the increasing number of samples to be analyzed, cost-efficient automation concepts for surface analysis are needed that can be realized with affordable and preferably commercial instrumentation.[5] Here, we provide an overview of analytical methods for FG analysis and quantification used by us for quantifying broadly utilized FGs and ligands on different types of NMs with electrochemical titration methods, optical assays, nuclear magnetic resonance (NMR) and vibrational (IR) spectroscopy, and X-ray based and thermal analysis methods.[1,2] Thereby, method- and material-related challenges are addressed, and the importance of multi-method characterization approaches easing method validation by method cross-validation. Special emphasis is dedicated to simple, versatile, and cost-efficient methods such as optical assays and electrochemical titration methods. T2 - eMRS Fall Meeting 2025 CY - Warsaw, Poland DA - 15.09.2025 KW - Quality assurance KW - Fluorescence KW - Nano KW - Particle KW - Synthesis KW - Characterization KW - Advanced material KW - Surface KW - Standardization KW - Reference material KW - Functional group KW - Quantification KW - Coating KW - Interlaboratory comparison KW - Uncertainty PY - 2025 AN - OPUS4-64183 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Quantifying the total and accessible amount of surface functionalities and ligands on nanomaterials N2 - Engineered nanomaterials (NMs) of various chemical composition and surface functionalization are routinely fabricated for industrial applications such as medical diagnostics, drug delivery, sensing, catalysis, energy conversion and storage, opto-electronics, and information storage. NM dispersibility, stability, processability, and function as well as the interaction with biological species and environmental fate are largely determined by NM surface functionalities, i.e., functional groups (FGs) and ligands. Therefore, reliable, reproducible, and eventually standardized surface characterization methods are vital for quality control of NMs, and mandatory to meet increasing concerns regarding their safety. Suitable methods for determining surface functionalities on ligand-stabilized core and core/shell NPs include advanced techniques such as traceable quantitative nuclear magnetic resonance (qNMR) as well as X-ray electron spectroscopy (XPS) and time of flight secondary ion mass spectrometry (ToF-SIMS), and simpler optical and electrochemical methods.[1] The latter less costly and fast methods, which can be automated, are often used by NM producers for process and quality control.[1,2] To validate methods, establish measurement uncertain-ties, test reference materials, and produce reference data, multi-method characterization studies are needed.[3,4] as well as interlaboratory comparisons (ILC) on determining NM surface chemistry and well characterized test and reference NMs providing benchmark values.[5,6] Here, we present examples for quantifying common surface FGs such as amino and carboxyl groups on functional NMs of different chemical composition such as silica, polymer, iron oxide, and lanthanide-based upconversion nanoparticles with optical assays, electrochemical titration methods, qNMR, and chromatographic separation techniques. In addition, ongoing interlaboratory comparisons will be presented. T2 - Yucomat 2025 CY - Herec Novi, Montenegro DA - 01.09.2025 KW - Quality assurance KW - Fluorescence KW - Nano KW - Particle KW - Synthesis KW - Characterization KW - Advanced material KW - Surface KW - Standardization KW - Reference material KW - Functional group KW - Quantification KW - Coating KW - Interlaboratory comparison KW - Uncertainty PY - 2025 AN - OPUS4-64182 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - From molecular and nanoscale chromophores with UV/VIS/NIR/SWIR luminescence to multi method characterization of surface coatings N2 - An overview of the research activities of division Biophotonics is presented covering examples for photophysical studies of different types of molecular and nanocrystalline luminophores, luminescent particles, and sensor systems in solution, in dispersion, and in the solid state and multi-method charactreization workflow for the characterization of surface-functionalized engineered nanomaterials. In addition, the importance of reliable optical measurements, particularly standardized workflows for the determination of the key performance parameter luminescence quantum yield of transparent and scattering luminescent samples with fluorescence and integrating sphere spectroscopy, and validated methods for quantifying surface functional groups and ligands on nanomaterials is highlighted. Thereby, also ongoing standardization activities are presented as well as certified reference materials and reference materials from division Biophotonics. T2 - Chinese-German Chemical Association - Annual Meeting CY - Berlin, Germany DA - 22.08.2025 KW - Quality assurance KW - Fluorescence KW - Nano KW - Particle KW - Synthesis KW - Quantum yield KW - Characterization KW - Advanced material KW - Surface KW - Lifetime KW - Sensor KW - Oxygen KW - Ph KW - Standardization KW - Fluorescent probe KW - Reference material PY - 2025 AN - OPUS4-64181 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Tavernaro, Isabella A1 - Abram, Sarah-Luise A1 - Homann, Christian A1 - Scholtz, Lena A1 - Radnik, Jörg A1 - Resch-Genger, Ute T1 - Validated and standardized measurements and quantification of surface functionalities on nanoparticles N2 - Surface-functionalized organic and inorganic engineered nanomaterials (NMs) are widely applied in the life and materials sciences. NM performance depends on key factors such as particle size and shape, crystal phase, morphology, chemical composition, and surface chemistry, i.e., surface coatings, functional groups (FGs), and ligands.1 The latter controls their processability and interaction with the environment and largely their possible toxicity. Thus, methods for FG quantification are important tools for quality control of NM production processes and can foster the sustainable development of functional and safe(r) NMs. This underlines the importance of validated and standardized analytical methods for surface analysis and reference materials.2 This encouraged us to explore simple and versatile tools for quantifying common bioanalytically relevant FGs such as optical assays, electrochemical titration methods, quantitative nuclear magnetic resonance spectroscopy (qNMR), and X-Ray photoelectron spectroscopy (XPS) and to perform a first interlaboratory comparison (ILC) on surface FG quantification.3,4 In a follow-up ILC, BAM and NRC explored qNMR sample preparation, measurement, and data evaluation protocols for commercial and custom-made aminated SiO2 NPs with sizes of 20-100 nm, different amounts of surface amino FGs, and different porosity.5,6 First, the number of amino FGs accessible for a dye reporter was determined with a cost-efficient, automated optical fluorescamine assay. Then, qNMR workflows and protocols were stepwise fine-tuned. The qNMR ILC was complemented by joint XPS measurements. BAM also examined the applicability of fast and automatable potentiometric titrations to screen the total amount of (de)protonable FGs on aminated SiO2 NPs. Our results underline the need to evaluate protocols for FG quantification in ILCs and the advantages of multi-method characterization strategies for efficient method cross validation. T2 - Surface and Micro/Nano Analysis Working Group CY - Paris, France DA - 08.04.2025 KW - Quality assurance KW - Reference material KW - Fluorescence KW - Nano KW - Particle KW - Surface analysis KW - XPS KW - Traceability KW - Metrology KW - Calibration KW - Reference data KW - Reference product KW - Digital certificate KW - QNMR KW - Potentiometry PY - 2025 AN - OPUS4-62969 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute A1 - Tavernaro, Isabella A1 - Abram, Sarah-Luise A1 - Homann, Christian A1 - Scholtz, Lena A1 - Radnik, Jörg T1 - Validated and standardized measurements and quantification of surface functionalities on nanoparticles N2 - Engineered nanoparticles (NPs) with various chemical compositions and surface functionalities are routinely fabricated for industrial applications such as medical diagnostics, drug delivery, sensing, catalysis, energy conversion and storage, opto-electronics, and information storage which improve the quality of life and European prosperity. Nanoparticle function, interaction with biological species, and environmental fate are largely determined by surface functionalities. Reliable, reproducible, and standardized surface characterization methods are therefore vital for quality control of NPs, and mandatory to meet increasing concerns regarding their safety. Also, industry, regulatory agencies, and policymakers need validated traceable measurement methods and reference materials. Industry, e.g., must comply with various regulations, including the chemicals´ regulation REACH (2006/1907) and cosmetic products regulation (2009/1223), depending on the use. Therefore, standardization organizations such as the European Committee for Standardization (CEN), the International Organization for Standardization (ISO), and the International Electrotechnical Commission (IEC) as well as industrial stakeholders, European Medicine Agency (EMA), and the nanosafety community responsible for guidelines for nanomaterial (NM) regulation like the Organisation for Economic Co-operation and Development (OECD) have expressed needs for standardized methodologies to measure NP surface chemical properties. Despite these needs, methodologies for determining NP surface properties, including the amount, chemical composition, and homogeneity of surface functionalities and coatings are largely non-standardized. Specifically, validated quantitative procedures for the measurement of thickness and composition of nanoparticle coatings and other surface functionalities are needed. Suitable methods for determining surface functionalities on ligand-stabilized core and core/shell NPs include advanced techniques such as traceable quantitative nuclear magnetic resonance (qNMR) as well as X-ray electron spectroscopy (XPS) and time of flight secondary ion mass spectrometry (ToF-SIMS), and simpler optical and electrochemical methods. The latter less costly methods are often used by SMEs, e.g., for quality control. To validate methods, establish measurement uncertainties, test reference materials, and produce reference data, international interlaboratory comparisons (ILC) on NP surface functionalization measurements are required. These needs have been addressed by us in two interlaboratory comparisons, that will be presented. In addition, the European metrology project SMURFnano will be briefly presented involving 12 partners from different National Metrology Institutes, designated institutes, and research institutes, two university groups as well as one large company and one SME producing NPs. T2 - NanoCarbon Annual Conference 2025 CY - Würzburg, Germany DA - 18.03.2025 KW - Nano KW - Particle KW - Silica KW - Quality assurance KW - Reference material KW - Surface chemistry KW - Size KW - Shape KW - Particle number concentration KW - Method KW - Optical assay KW - QNMR KW - Validation KW - Potentiometry KW - XPS PY - 2025 AN - OPUS4-62790 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Andresen, Elina T1 - Lanthanide based multi element nanoparticles: a versatile platform for surface chemistry analysis and potential reference materials N2 - The use of engineered nanoparticles of different size, shape, and composition is continuously increasing in the life and materials sciences. This calls for methods and reference materials enabling the reliable and accurate determination of nanoparticle size, particle size distribution, shape, number concentration, degree of aggregation and agglomeration in different environments as well as for nanoparticle dispersibility and stability. We are currently building up and exploring a platform of lanthanide-based nanocrystals (LnNCs) with application-specifically tuned size, shape, composition, architecture, optical properties, and surface chemistry for emerging applications in life sciences. As a prerequisite for the broad applicability of these nanomaterials, we assess simple, robust, and easily upscaleable synthesis protocols for LnNCs with defined morphologies and tunable optical properties, and the short-term and long-term stability of LnNCs with selected surface coatings in aqueous environments under different application-relevant conditions. T2 - Anakon 2025 CY - Leipzig, Germany DA - 10.03.2025 KW - Nano KW - Particle KW - Method KW - Lanthanide KW - Synthesis KW - Upconversion KW - Ligand KW - Quality assurance KW - Particle number concentration KW - Reference material KW - Surface chemistry PY - 2025 AN - OPUS4-62768 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Tavernaro, Isabella T1 - Where Do We Stand – Quantifying Amino Groups on Silica (Nano)Particles N2 - Industry and regulators are increasingly requesting validated and standardized measurement protocols to support the manufacturing, quality control, and safe use of engineered nanomaterials. Addressing a remaining gap in method development and standardization for nanomaterial characterization, we investigated in a bilateral comparison various methods commonly used for surface functional group quantification, like quantitative nuclear magnetic resonance (qNMR) spectroscopy, x-ray photoelectron spectroscopy (XPS), and optical assays. These results demonstrate not only an influence of the size and synthesis methods on the number of surface functional groups for differently sized commercial and in-house synthesized silica nanoparticles but also on their functionality. T2 - Kickoff-Meeting SMURFnano CY - Berlin, Germany DA - 09.07.2024 KW - Nano KW - Particles KW - Silica KW - Synthesis KW - Quantification KW - Functional groups KW - Quality assurance KW - Reference material KW - Interlaboratory comparison KW - Method KW - Uncertainty KW - Sensor KW - Surface analysis PY - 2024 AN - OPUS4-62164 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Tavernaro, Isabella T1 - Rational Design of Analyte-responsive Fluorescent Particle Sensors for Life Sciences Applications N2 - Engineered and tailor-made nanomaterials (NM) are of increasing relevance for current and future developments in the life and material sciences for applications, e.g., as drug carriers, fluorescent sensors, and multimodal labels in bioanalytical assays, and reporters for imaging applications. For instance, NM-based reporters and sensors, that are labelled or stained with a multitude of conventional or sensor dyes, have several advantages as compared to molecular probes like enhanced brightness, i.e., amplified signals, ease of designing ratiometric systems by combining analyte-sensitive and inert reference dyes, and increased photostability. Moreover, this can enable the use of hydrophobic dyes in aqueous environments. For rational NM design, choosing and tailoring the intrinsic physicochemical properties, such as particle size, size distribution, morphology, and surface chemistry of the NM application-specific considerations like biocompatibility, ease and low cost of preparation, and colloidal stability and performance in the targeted environment must be considered. In this lecture, different design concepts of inorganic, organic, and hybrid NM and microparticles with hydrophilic surface chemistries and different functionalities are presented that can be used for the targeting of lysosomes; and to monitor functional parameters of endo-lysosomal compartments, like pH or enable oxygen sensing. T2 - Chemical Probes for Lysosomal Biology CY - York, United Kingdom DA - 09.09.2024 KW - Luminescence KW - Quantification KW - Nano KW - Particle KW - Quality assurance KW - Fluorescence KW - Method KW - Uncertainty KW - Reference material KW - Sensor KW - Synthesis KW - Dye KW - pH KW - Silica KW - Polystyrene KW - Surface analysis PY - 2024 AN - OPUS4-62173 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Tavernaro, Isabella T1 - How to Quantify the Total and Accessible Number of Functional Groups and Ligands on Nanomaterials Using a Multimodal Approach – A Bilateral Comparison N2 - Surface-functionalized organic and inorganic engineered nanomaterials (NM) have gained increasing interest in various fields of application such as nanomedicine, bioimaging and sensing, or as additives in food and consumer products. The performance and safe use of these NM in such applications depend not only on their composition, primary particle size, and morphology, but also on surface chemistry, which controls surface charge, colloidal stability, biocompatibility, and toxicity.[1] NM surface chemistry is mainly determined by the total number of surface functional groups (FG) and the number of FG accessible for subsequent functionalization with ligands or biomolecules. Thus, methods for FG quantification are not only important tools for the control of NM production processes, but can also foster the sustainable development of functional and safe(r) NM. In addition, this need underlines the importance of validated and standardized analytical methods that provide accurate information on application-relevant physicochemical properties with known uncertainties, flanked by suitable quality control samples and reference materials. Aiming at the development of simple, versatile, and multimodal tools for the quantification of common bioanalytically relevant FG, we investigated and compared various analytical methods commonly used for FG quantification.[2,3] The potential of multimodal approaches for FG quantification was recently demonstrated in a bilateral comparison of the surface analysis of commercially available aminated silica nanoparticles (SiO2-NP).[3] These results demonstrate not only an influence of the size and synthesis methods on the number of FG but also on NM performance. This concept is currently explored in a second bilateral comparison of quantitative nuclear magnetic resonance (qNMR) measurements and optical assays for differently sized commercial and in-house synthesized SiO2-NP with varying amounts of amine functionalities, utilizing further optimized protocols for sample preparation, qNMR measurements, and data evaluation. This strategy can contribute to establishing multi-method characterization strategies for NMs and can provide a more detailed picture of structure-properties relationships for different types of functional NM. T2 - E-MRS Spring Meeting 2024 & ALTECH 2024 CY - Strasbourg, France DA - 27.05.2024 KW - Quantification KW - Nano KW - Particle KW - Quality assurance KW - Interlaboratory comparison KW - Method KW - Uncertainty KW - Reference material KW - Sensors KW - Synthesis KW - Silica KW - Surface analysis PY - 2024 AN - OPUS4-62161 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Schweizer, S. T1 - Interlaboratory comparison on absolute PL quantum yield measurements of scattering luminescent materials N2 - Optical measurements of scattering luminescent materials dispersed in liquid and solid matrices and luminescent powders play an important role in fundamental research and industry. Typical examples are luminescent nano- and microparticles and phosphors of different composition in different matrices or incorporated into ceramics with applications in energy conversion, solid-state lighting, medical diagnostics, and security barcoding. The key parameter for the performance of these materials is the photoluminescence quantum yield QY, i.e., the number of emitted photons per number of absorbed photons. QY of transparent luminophore solutions can be determined relatively to a fluorescence quantum yield standard of known QY. Such standards are meanwhile available as certified reference materials.[1] The determination of QY of scattering liquid and solid samples like dispersions of luminescent nanoparticles, solid phosphors, and optoceramics requires, however, absolute measurements with an integrating sphere setup. Although the importance of reliable absolute QY measurements has been recognized, no interlaboratory comparisons (ILCs) on measurement uncertainties and the identification of typical sources of uncertainty have been yet reported. Also, no scattering reference materials with known QY are available. We present here the results of a first ILC of 3 laboratories from academia and industry performed to identify and quantify sources of uncertainty of absolute QY measurements of scattering samples. Thereby, two types of commercial stand-alone integrating sphere setups with different illumination and detection geometries were utilized for measuring QY of transparent and scattering dye solutions and solid phosphors. As representative and industrially relevant solid and scattering samples, YAG:Ce optoceramics of varying surface roughness were chosen, applied, e.g., as converter materials for blue light emitting diodes. Special emphasis was dedicated to the influence of the measurement geometry, the optical properties of the blank, utilized to determine the number of photons of the incident excitation light absorbed by the sample, and the sample-specific surface roughness. While matching QY values could be obtained for transparent dye solutions and scattering dispersions, here using a blank with scattering properties closely matching those of the sample, QY measurements of optoceramic samples with different blanks revealed substantial differences, with the blank's optical properties accounting for measurement uncertainties of more than 20 %. Based upon the ILC results, we recommend non-absorbing blank materials with a high reflectivity (>95 %) such as a 2 mm-thick PTFE target placed on the sample holder which reveals a near-Lambertian light scattering behavior, yielding a homogeneous light distribution within the integrating sphere. T2 - 8th IWASOM CY - Gdánsk, Poland DA - 07.07.2024 KW - Nano KW - Particle KW - Fluorescence KW - Quantum yield KW - Method KW - Sensor KW - Film KW - Absolute quantum yield KW - Scattering KW - YAG:Ce KW - Quality assurance KW - Lanthanide KW - Upconverter KW - LED KW - Uncertainty KW - Standardization KW - Reference material PY - 2024 AN - OPUS4-62100 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Altmann, Korinna T1 - Mikroplastik heute: Was haben wir in den letzten Jahren erreicht? N2 - In diesem Vortrag geht es um eine Übersicht über die Thematik der Mikroplastik, Was ist Mikroplastik, wie entsteht es und wo kommt es her. Es wird beschrieben wie eine repräsentative Probenahme erfolgen kann und wie welche Herausforderungen bei der Probenvorbereitung existieren. Die Detektion wird ausführlich beschrieben, sowohl mit Partikelanzahl als auch Masse. Im weiteren werden erste Referenzmaterialien und ihre Anwendung in internationalen Ringversuchen beschrieben. Der zweite Teil zeigt die Normungsaktivitäten im Bereich der Mikroplastik. T2 - Mitgliederversammlung der GdCh Lackchemie CY - Online Meeting DA - 20.09.2024 KW - Mikroplastik KW - TED-GC/MS KW - Polymer 3R KW - Reference material KW - ILC on detection methods PY - 2024 AN - OPUS4-61087 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Getting it right with photoluminescence quantum yields of molecular and nanoscale luminophores and luminescent particles N2 - Photophysical and mechanistic studies, the comparison of different emitter classes, and the rational design of the next generation of molecular and nanoscale reporters require quantitative photoluminescence measurements and the reliable determination of the key performance parameter photoluminescence quantum yield (QY), i.e., the number of emitted per absorbed photons. This is of special importance for all photoluminescence applications in the life and material sciences in the UV/vis/NIR/SWIR. To improve the reliability and comparability of photoluminescence and QY measurements across laboratories, pitfalls, achievable uncertainties, and material-specific effects related to certain emitter classes must be explored. Also, suitable protocols and reference materials are needed which have been validated in interlaboratory comparisons for different wavelength regions and transparent and scattering luminophores.[1] Based on absolute and relative photoluminescence measurements of functional dyes and nanomaterials like semiconductor quantum dots and rods, spectrally shifting lanthanide upconversion nanocrystals, perovskites, and YAG:Cer converter materials, reliable methods for determining QY of transparent and scattering luminophores, nonlinear emitters, and solid luminescent nanomaterials have been developed.[2,3] Thereby, material- and method-related uncertainties of relative and absolute QY measurements and achievable uncertainties could be quantified for linear and nonlinear UV/vis/NIR/SWIR emitters and lately for also luminescent and scattering materials and solid phoshors, here in an interlaboratory comparison of three labs utilizing integrating sphere spectroscopy.[4,5] In addition, to provide simple tools for a better comparability of QY measurements, recently, a first set of UV/vis/NIR quantum yield standards has been developed and certified with complete uncertainty budgets.[6] In the following, the outcome of these studies will be presented, thereby addressing common pitfalls and providing recommendations on the performance of reliable QY measurements of linear and non-linear emitters in transparent, scattering, and solid samples. T2 - 29th Lecture Conference on Photochemistry (LCP 2024) GDCh CY - Mainz, Germany DA - 16.09.2024 KW - Nanoparticle KW - Nano KW - Luminescence KW - Quality assurance KW - Synthesis KW - Standardization KW - Reference material KW - Quantum yield KW - Fluorescence KW - Reference data KW - Integrating sphere spectroscopy KW - ILC KW - Converter material KW - YAG:Ce KW - Optoceramic PY - 2024 AN - OPUS4-61075 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Photoluminescence quantum yields of molecular & nanoscale luminophores in the UV/VIS/NIR/SWIR in dispersion and in the solid state N2 - Photophysical and mechanistic studies, the comparison of different emitter classes, and the rational design of the next generation of molecular and nanoscale reporters require quantitative photoluminescence measurements and the reliable determination of the key performance parameter photoluminescence quantum yield (QY), i.e., the number of emitted per absorbed photons. This is of special importance for all photoluminescence applications in the life and material sciences in the UV/vis/NIR/SWIR. T2 - MAF 2024 Conference CY - Valencia, Spain DA - 08.09.2024 KW - Nanoparticle KW - Nano KW - Luminescence KW - Quality assurance KW - Synthesis KW - Standardization KW - Reference material KW - Quantum yield KW - Fluorescence KW - Reference data KW - Integrating sphere spectroscopy KW - ILC KW - Converter material PY - 2024 AN - OPUS4-61072 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute A1 - Tavernaro, Isabella A1 - Abram, Sarah-Luise A1 - Andresen, Elina A1 - Matiushkina, Anna T1 - Quantifying the number of total and accessible functional groups on nanomaterials N2 - Inorganic and organic functional nanomaterials (NM) of different size, shape, chemical composition, and surface chemistry are relevant for many key technologies of the 21st century. Decisive for most applications of NM are their specific surface properties, which are largely controlled by the chemical nature and number of ligands and functional groups (FG on the NM surface. The surface chemistry can strongly affect the physicochemical properties of NM, their charge, hydrophilicity/hydrophobicity, reactivity, stability, and processability and thereby their impact on the environment and biological species as well as their possible risk for human health. Thus, reliable, validated, and eventually standardized analytical methods for the characterization of NM surface chemistry, i.e., the chemical identification, quantification, and accessibility of FG and surface ligands 1,2] flanked by interlaboratory comparisons, control samples, and reference materials, 2 ,3 are of considerable importance for process and quality control of NM production and function. This is also important for the safe use of NM the design of novel NM, and sustainable concepts for NM fabrication. Here, we provide an overview of analytical methods for FG analysis and quantification and highlight method and material related challenges for selected NM. Analytical techniques address ed include electrochemical titration methods, optical assays, nuclear magnetic resonance (NMR) and vibrational (IR) spectroscopy, and X ray based and thermal analysis methods. Criteria for method classification and evaluation include the need for a signal generating label, provision of either the total or derivatizable number of FG, and suitability for process and production control. T2 - AUC - Analytical Ultracentrifugation CY - Nuremberg, Germany DA - 22.07.2024 KW - Nanoparticle KW - Particle KW - Microparticle KW - Silica KW - Quantum dot KW - Polymer KW - Surface group KW - Luminescence KW - Quality assurance KW - Synthesis KW - Surface modification KW - ILC KW - Optical assay KW - Functional group KW - Ligand KW - qNMR KW - Conductometry KW - Potentiometry KW - Standardization KW - Reference product KW - Reference material PY - 2024 AN - OPUS4-60749 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Absolute Determination of Photoluminescence Quantum Yields of Scattering LED Converter Materials – How to Get it Right N2 - Optical measurements of scattering luminescent materials dispersed in liquid and solid matrices and luminescent powders play an important role in fundamental research and industry. Typical examples are luminescent nano- and microparticles and phosphors of different composition in different matrices or incorporated into ceramics with applications in energy conversion, solid-state lighting, medical diagnostics, and security barcoding. The key parameter for the performance of these materials is the photoluminescence quantum yield QY, i.e., the number of emitted photons per number of absorbed photons. QY of transparent luminophore solutions can be determined relatively to a fluorescence quantum yield standard of known QY. Such standards are meanwhile available as certified reference materials.[1] The determination of QY of scattering liquid and solid samples like dispersions of luminescent nanoparticles, solid phosphors, and optoceramics requires, however, absolute measurements with an integrating sphere setup. Although the importance of reliable absolute QY measurements has been recognized, no interlaboratory comparisons (ILCs) on measurement uncertainties and the identification of typical sources of uncertainty have been yet reported. Also, no scattering reference materials with known QY are available. We present here the results of a first ILC of 3 laboratories from academia and industry performed to identify and quantify sources of uncertainty of absolute QY measurements of scattering samples. Thereby, two types of commercial stand-alone integrating sphere setups with different illumination and detection geometries were utilized for measuring QY of transparent and scattering dye solutions and solid phosphors. As representative and industrially relevant solid and scattering samples, YAG:Ce optoceramics of varying surface roughness were chosen, applied, e.g., as converter materials for blue light emitting diodes. Special emphasis was dedicated to the influence of the measurement geometry, the optical properties of the blank, utilized to determine the number of photons of the incident excitation light absorbed by the sample, and the sample-specific surface roughness. While matching QY values could be obtained for transparent dye solutions and scattering dispersions, here using a blank with scattering properties closely matching those of the sample, QY measurements of optoceramic samples with different blanks revealed substantial differences, with the blank's optical properties accounting for measurement uncertainties of more than 20 %. Based upon the ILC results, we recommend non-absorbing blank materials with a high reflectivity (>95 %) such as a 2 mm-thick PTFE target placed on the sample holder which reveals a near-Lambertian light scattering behavior, yielding a homogeneous light distribution within the integrating sphere. T2 - e-MRS 2024 CY - Strasbourg, France DA - 27.05.2024 KW - Luminescence KW - Quantitative spectroscopy KW - Nano KW - Particle KW - Quantum yield KW - Lifetime KW - Quality assurance KW - Phosphor KW - Converter marterial KW - Fluorescence KW - Interlaboratory KW - Comparison KW - Method KW - Uncertainty KW - Reference material PY - 2024 AN - OPUS4-60490 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Characterization and quantification of functional groups and coatings on nanoobjects an overview N2 - Characterization of Nanoparticles – Questions to Ask, Functional Nanoparticles (NPs) – Organic, Inorganic, and Hybrid Nanoparticles Nanomaterial Characterization Standardization – Addressing Remaining Gaps Surface FGs Particle Surface Chemistry - Why is it Important? Particle Surface Chemistry - A Key Driver for Performance, Applications, and Safety Aspects Method Development for Quantifying FGs and Ligands on Particle Surfaces FG Quantification – Method Choice & Criteria Relevant for Data Interpretation Quantifying the Amount of Total and Accessible FGs on Aminated Silica Nanoparticles (SiO2-NH2) Comparing the Total and Accessible –NH2 Content on Aminated Silica NPs of Different Size Characterization of Nanoparticles Standardization Standardized Measurements of Surface FGs on Nanoparticles EMP Project SMURFnano EMP Project SMURFnano Work Packages & Goals Certified Reference Materials from BAM T2 - e-MRS 2024 (Spring Meeting of the European Materials Research Society, Altech Symposium) CY - Strasbourg, France DA - 27.05.2024 KW - Luminescence KW - Nano KW - Particle KW - Quantum yield KW - Quality assurance KW - Interlaboratory comparison KW - Method KW - Uncertainty KW - Reference material KW - Surface analysis KW - Optical assay KW - NMR KW - Silica KW - Ligand PY - 2024 AN - OPUS4-60495 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Altmann, Korinna T1 - Preliminary results of an interlaboratory comparison on microplastics organised by plasticsfate N2 - Microplastics are everywhere in the environment, but analytics is challenging. Since harmonisation is missing as well es suitable reference materials, BAM did under th umbrella of VAMAS funded by the EU Horizon 2020 project PlasticsFate a ILC for microplastic detection methods. Methods adressed were IR, Raman, Py-GC/MS and TED-GC/MS. The talk gives a first presentation and evaluation on the results. T2 - CUSP annual meeting and conference CY - Utrecht, Netherlands DA - 12.09.2023 KW - Microplastics KW - TED-GC/MS KW - Polymer 3R KW - Reference material KW - ILC on detection methods PY - 2023 AN - OPUS4-60036 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Wiesner, Yosri T1 - Reference material candidates for Microplastic analysis N2 - Microplastic reference material is required for validation and harmonization purposes. This includes the analysis of the pure polymer particles and the validation of the respective measurement methods. In addition, there is the harmonization of different laboratories. On the other hand, sample preparation methods must be validated and harmonized with regard to their recovery and subsequent analysis in the respective matrices. For this purpose, we produce reference material candidates in the form of tablets with different mass fractions and particle numbers of polyethelene terephthalate. In the presentation first measurement results by µ-Raman, µ-FTIR, pyrolysis-GC-MS and TED-GC/MS will be presented. T2 - SETAC Europe 34th Annual Meeting CY - Seville, Spain DA - 05.05.2024 KW - Reference material KW - Microplastics KW - PlasticTrace PY - 2024 AN - OPUS4-60019 LA - deu AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Tavernaro, Isabella T1 - A Multimodal Approach to Quantify Surface Functional Groups and Ligands on Amorphous Silica Nanoparticles N2 - Nowadays amorphous silica nanoparticles (SiO2-NP) are one of the most abundant engineered nanomaterials, that are highly stable and can be easily produced on a large scale at low cost. Surface functionalized SiO2-NP are of great interest in the life and material sciences, as they can be used e.g. as drug carriers, fluorescent sensors, and multimodal labels in bioanalytical assays and imaging applications. Their performance in such applications depends not only on particle size, size distribution, and morphology, but also on surface chemistry, i.e. the total number of surface functional groups (FG) and the number of FG accessible for subsequent functionalization with ligands or biomolecules, which in turn determines surface charge, colloidal stability, biocompatibility, and toxicity. Aiming at the development of simple, versatile, and multimodal tools for the quantification of many bioanalytically relevant FG and ligands, we investigated and compared various analytical methods commonly used for FG quantification. This includes electrochemical titration methods, dye-based optical assays, and other instrumental analytical techniques such as nuclear magnetic resonance and thermal analysis methods. The potential of our multimodal approach for FG quantification was demonstrated for commercial and custom-made silica particles of varying FG, showing not only an influence of the synthesis methods on the number of FG but also on the performance. In the future, our strategy can contribute to establish multi-method characterization strategies to provide a more detailed picture of the structure-properties relationship. T2 - Advanced Materials Safety 2023 CY - Saarbrücken, Germany DA - 08.11.2023 KW - Amorphous silica particles KW - Surface group analysis KW - Ligands KW - Reference material KW - Optical spectroscopy KW - Quantitative NMR KW - Optical assays KW - Titration KW - Engineered nanomaterials KW - Advanced Materials PY - 2023 AN - OPUS4-59124 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Design and Quantitative Characterization of Functional Molecular Chromophores and Nanomaterials with UV/vis/NIR/IR Emission – An Overview of Research Activities in Division Biophotonics N2 - In the focus of division Biophotonics are the design, preparation, analytical and spectroscopic characterization, and application of molecular and nanoscale functional materials, particularly materials with a photoluminescence in the visible, near infrared (NIR) and short-wave infrared (SWIR). This includes optical reporters for bioimaging and sensing, security and authentication barcodes, and materials for solid state lighting, energy conversion, and photovoltaics. For the identification of optimum particle structures quantitative spectroscopic studies are performed under application-relevant conditions, focusing on the key performance parameter photoluminescence quantum yield. In addition, simple, cost-efficient, and standardizable strategies for quantifying functional groups on the surface of nano- and microparticles are developed, here with a focus on optical assays and electrochemical titration methods, cross-validated by more advanced methods such as quantitative NMR. In addition, reference materials and reference products are developed for optical methods, particularly luminescence techniques, and for analytical methods utilized for the characterization of nanomaterials. T2 - Projekttreffen Nile-Chrome 2.0 CY - Mainz, Germany DA - 11.12.2023 KW - Fluorescence KW - Quantum yield KW - Optical spectroscopy KW - Reference material KW - Reference data KW - Quality assurance KW - Dye KW - Reference product KW - NIR KW - SWIR KW - Nano KW - Particle KW - Silica KW - Polymer KW - Surface group analysis KW - Sensor molecules PY - 2023 AN - OPUS4-59123 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Petrov, Eugene A1 - Würth, Christian A1 - Richter, Maria A1 - Resch-Genger, Ute T1 - Fluorescence Standards from BAM - Dye Solutions and Polymer systems N2 - For fluorescence microscopy, there is an increasing need for suitable calibration tools and reference materials for microscope calibration, the determination of performance parameters, and the regular control and validation of instrument performance. This is addressed in the BmWk-financed project FluMikal (WIPANO program) by two research groups from academia and two companies, that is coordinated by BAM. Here we present different approaches to liquid and solid fluorescence standards for the determination of the wavelength-dependent spectral sensitivity of fluorescence microscopes and ideas concerning the choice of suitable fluorescence lifetime standard for increasingly utilized fluorescence lifetime imaging (FLIM). T2 - FluMiKal Projectmeeting CY - Munich, Germany DA - 27.11.2023 KW - Reference material KW - Reference product KW - Fluorescence microscopy KW - Quality assurance KW - Instrument performance validation KW - Lifetime standard PY - 2023 AN - OPUS4-59120 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Forschung in einer Bundesoberbehörde wie der BAM N2 - Die Bundesanstalt für Materialforschung und -prüfung (BAM) ist eine forschende Bundesoberbehörde und Einrichtung der Ressortforschung der Bundesrepublik Deutschland. Unter ihrer Leitlinie „Sicherheit in Technik und Chemie“ ist sie zuständig für die öffentliche technische Sicherheit und für metrologische Aufgaben in der Chemie. Das Aufgabenspektrum der BAM, das sich an aktuellen Fragestellungen aus Wissenschaft, Wirtschaft, Politik und Normung orientiert, bietet sehr viele interessante Tätigkeitsfelder für Naturwissenschaftler*Innen und Ingenieur*Innen. T2 - WIFO Leipzig 2023 CY - Leipzig, Germany DA - 05.09.2023 KW - Quality assurance KW - Optical spectroscopy KW - Certification KW - Reference product KW - Integrating sphere spectroscopy KW - Fluorescence KW - Quantum yield KW - Reference material KW - Reference data KW - Traceability KW - Nano KW - Particle KW - Analytical chemistry KW - Sensor KW - Safety PY - 2023 AN - OPUS4-58397 LA - mul AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute A1 - Wegner, Karl David T1 - Luminescent Nanoparticles – From Photophysics to the Measurement of Photoluminescence Quantum Yields N2 - Inorganic nanocrystals with linear and nonlinear photoluminescence in the ultraviolet, visible, near infrared and short-wave infrared like spectrally shifting lanthanide-based nanoparticles (LnNCs) like NaYF4: Yb, Er and semiconductor quantum dots have meanwhile found applications in the life and material sciences ranging from optical reporters for bioimaging and sensing over security barcodes to solid state lighting and photovoltaics. The identification of optimum particle architectures for photonic applications requires quantitative spectroscopic studies, ideally flanked by single particle studies to assess spectroscopic inhomogeneities on a particle-to-particle level for typical preparation methods. In the following, photoluminescence studies of LnNCs are presented, addressing parameters such as particle size, surface coating, and dopant ion concentration as well as excitation power density mandatory for a profound mechanistic understanding of the nonradiative deactivation pathways in these nanocrystals. In addition, methods for the determination of particle brightness and photoluminescence quantum yield in different spectral windows are presented. T2 - Phoenix Colloquium CY - Hannover, Germany DA - 22.06.2023 KW - Semiconductor quantum dot KW - Upconversation nanocrystal KW - Luminescence KW - Quantitative spectroscopy KW - Photophysics KW - Quality assurance KW - Nano KW - Particle KW - Quantum yield KW - Lifetime KW - Standard KW - Reference material KW - Surface analysis KW - Quantification PY - 2023 AN - OPUS4-57797 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Vogl, Jochen T1 - Isotope Ratio Measurements and Certification of iCRMs at BAM N2 - A short overview on isotope ratio measurements at BAM and related CRM activities is given. The current isotope CRM range offered by BAM and future iCRM projects are presented. T2 - CCQM IRWG Meeting CY - Sevres, France DA - 24.04.2023 KW - Absolute isotope ratio KW - Reference material KW - Metrology KW - Traceability PY - 2023 AN - OPUS4-57399 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Applications of photoluminescence lifetime measurements in the life and material sciences N2 - Bioanalytical, diagnostic, and security applications require the fast and sensitive determination of a steadily increasing number of analytes or events in parallel in a broad variety of detection formats and increased sensitivities. This – flanked by recent technical advancements and the availability of simple to use, commercial time-resolved photoluminescence measuring devices at reasonable costs - calls for the exploitation of the species- and environment-specific photoluminescence parameter luminescence lifetime. In this context, time-resolved photoluminescence measurements of different classes of molecular and nanocrystalline emitter and luminescent particles in different time windows are presented and examples for applications such as lifetime multiplexing and barcoding in conjunction with fluorescence lifetime imaging microscopy (FLIM) and flow cytometry are given. T2 - Eingeladener Vortrag bei dem Workshop von Picoquant „Time-resolved fluorescence“ CY - Berlin, Germany DA - 17.11.2022 KW - Dye KW - Quantum dot KW - Upconversion nanocrystal KW - Luminescence KW - Quantitative spectroscopy KW - Photophysics KW - Quality assurance KW - Nano KW - Particle KW - Quantum yield KW - Lifetime KW - Standard KW - Reference material PY - 2022 AN - OPUS4-57048 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - New project on the quantification of functional groups (FGS) on nanomaterials N2 - The surface chemistry of nanomaterials controls their interaction with the environment and biological species and their fate and is hence also relevant for their potential toxicity. This has meanwhile led to an increasing interest in validated and preferably standardized methods for the determination and quantification of surface functionalities on nanomaterials and initiated different standardization projects within ISO/TC 229 and IEC/TC 113 as well as interlaboratory comparisons (ILCs) of different analytical methods for the quantification of surface coatings by OECD. Here we present the results of a first ILC on the quantification of the amount of amino functionalities on differently sized inorganic nanoparticles done by division Biophotonics and the National Research Council of Canada (NRC) and the PWI 19257 on the Characterization and Quantification of Surface Functional Groups and Coatings on Nanoobjects approved by ISO/TC 229 (WG2) in fall 2022 that will result in a VAMAS study on this topic organized by division Biophotonics. Key words: nanoparticles, surface analysis, surface functional groups, quantification, optical assay, qNMR, VAMAS, standardization, ICL, quality assurance, reference material. T2 - Eingeladener Vortrag Universität Erlangen CY - Erlangen, Germany DA - 18.01.2023 KW - Quality assurance KW - Nano KW - Particle KW - Standard KW - Reference material KW - Surface analysis KW - Quantification KW - Interlaboratory comparison KW - Standardization KW - VAMAS PY - 2023 AN - OPUS4-57044 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Functional Luminophores – From Photophysics to Standardized Luminescence Measurements N2 - Inorganic nanocrystals with linear and nonlinear luminescence in the ultraviolet, visible, near infrared and short-wave infrared like semiconductor quantum dots and spectrally shifting lanthanide-based nanophosphors have meanwhile found applications in the life and material sciences ranging from optical reporters for bioimaging and sensing over security barcodes to solid state lighting and photovoltaics. These nanomaterials commonly have increasingly sophisticated core/shell particle architectures with shells of different chemical composition and thickness to minimize radiationless deactivation at the particle surface that is usually the main energy loss mechanism [1]. For lanthanide-based spectral shifters, particularly for very small nanoparticles, also surface coatings are needed which protect near-surface lanthanide ions from luminescence quenching by high energy vibrators like O-H groups and prevent the disintegration of these nanoparticles under high dilution conditions. [2,3,4]. The identification of optimum particle structures requires quantitative spectroscopic studies focusing on the key performance parameter photoluminescence quantum yield [5,6], ideally flanked by single particle studies to assess spectroscopic inhomogeneities on a particle-to-particle level for typical preparation methods [7,8], Moreover, in the case of upconversion nanoparticles with a multi-photonic and hence, excitation power density (P)-dependent luminescence, quantitative luminescence studies over a broad P range are required to identify particle architectures that are best suited for applications in fluorescence assays up to fluorescence microscopy. Here, we present methods to quantify the photoluminescence of these different types of emitters in the vis/NIR/SWIR and as function of P and demonstrate the importance of such measurements for a profound mechanistic understanding of the nonradiative deactivation pathways in semiconductor and upconversion nanocrystals of different size and particle architecture in different environments. T2 - Eingeladener Vortrag Uni Erlangen CY - Erlangen, Germany DA - 18.01.2023 KW - Semiconductor quantum dot KW - Upconversion nanocrystal KW - Luminescence KW - Quantitative spectroscopy KW - Photophysics KW - Quality assurance KW - Nano KW - Particle KW - Quantum yield KW - Lifetime KW - Standard KW - Reference material KW - Surface analysis KW - Quantification PY - 2023 AN - OPUS4-57011 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Grimmer, Christoph T1 - Constant emitting reference material for material test procedures N2 - In industrialised countries more than 80% of the time is spent indoors. Products, such as building materials and furniture, emit volatile organic compounds (VOCs), which are therefore ubiquitous in indoor air. VOC in combination may, under certain environmental and occupational conditions, result in reported sensory irritation and health complaints. Emission concentrations can become further elevated in new or refurbished buildings where the rate of air exchange with fresh ambient air may be limited due to improved energy saving aspects. A healthy indoor environment can be achieved by controlling the sources and by eliminating or limiting the release of harmful substances into the air. One way is to use (building) materials proved to be low emitting. Meanwhile, a worldwide network of professional commercial and non-commercial laboratories performing emission tests for the evaluation of products for interior use has been established. Therefore, comparability of test results must be ensured. A laboratory’s proficiency can be proven by internal and external validation measures that both include the application of suitable emission reference materials (ERM). For the emission test chamber procedure according to EN 16516, no artificial ERM is commercially available. The EU-funded EMPIR project MetrIAQ aims to fill this gap by developing new and improved ERMs. The goal is to obtain a material with a reproducible and temporally constant compound release (less than 10% variability over 14 days). Different approaches, such as the impregnation of porous materials, are being tested. The generation as well as results of the most promising materials will be presented. T2 - Airmon 2022 CY - Bristol, UK DA - 07.11.2022 KW - Emission reference materials KW - Emission test chamber procedure KW - Quality assurance KW - Reference material PY - 2022 AN - OPUS4-56575 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Waniek, Tassilo T1 - MNP test and reference material production N2 - Reference materials are essential to analyze the impact of micro- and nanoplastics. The particle size D50 has been chosen as property of interest. They can be produced top-down by milling. For size separation down to a particle size D50 of 50 µm sieving is suitable while smaller particle sizes can be obtained by filtration. After production it is important to control the stability because microplastic in the size range below 10 µm tend to agglomerate. T2 - CUSP early-stage researchers meeting CY - Online meeting DA - 08.11.2022 KW - Particale size KW - Microplastic KW - Reference material KW - Cryo milling KW - Polymer PY - 2022 AN - OPUS4-56214 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Waniek, Tassilo T1 - The practical implementation of MP reference material production according to ISO standards N2 - Micro- and nanoplastic particles became a topic of public concern all over the world e.g. in water, soil, sludge and air. For a profound risk assessment, it is necessary to identify the origins, hotspots, or transport between different media. Therefore, a representative repeatable analysis is required and reference materials (RM) to proof and compare methods. The basis of MNP investigations is a harmonized analysis which includes sampling, sample preparation and detection. In recent years, spectroscopic methods like µRaman and µFTIR for the determination of particle numbers or thermoanalytical methods like Pyrolysis gas chromatography/mass spectrometry (py-GC/MS) and Thermo extraction/ desorption gas chromatography / mass spectrometry (TED-GC/MS) for mass determination have proven to be particularly suitable. The technical committees (TC) of ISO TC 61 “plastics” and TC 147 “water quality" are working on harmonisation processes on international level. For all standardization approaches, it is necessary that the detection methods and analysis processes can be validated. Therefore, BAM develops reference material for microplastic (MP) analysis for several years with focus on the most common polymers PE, PP, PS, PET and PA. MP particles with a close to reality fragment shape are obtained by cryomilling and sieving. For sample preparation purposes with mass detection methods MP particles are pressed into pills with a water-soluble matrix. Thereby losses due to sample preparation e.g. filtration are included in the verification of an analysis. To ensure a constant quality throughout all MP RM batches the homogeneity and stability is controlled according to ISO Guide 35. Next to TED-GC/MS measurements particle size distribution, infrared spectroscopy and differential scanning calorimetry spectra are taken as accompanying parameters. This presentation aims to introduce into the MP RM production process with ensured quality and special focus on pointing out customized setups for particle comminution, separation, and characterization for standardization. T2 - ASTM Syposioum on Microplastic Analytical and Reference Standards - Opportunities to Advance Microplastic Science CY - Seattle, WA, USA DA - 30.06.2022 KW - Microplastic KW - Reference material KW - Cryo milling KW - Polymer PY - 2022 AN - OPUS4-55891 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Pauli, Jutta A1 - Würth, Christian A1 - Güttler, Arne A1 - Resch-Genger, Ute T1 - Reliable Determination of the Signal-Relevant Spectroscopic Key Characteristics of Luminescent Reporters and Optical Probes for Imaging in the vis/NIR/SWIR N2 - Introduction. Comparing different emitter classes and rationally designing the next generation of molecular and nanoscale probes for bioimaging applications require accurate and quantitative methods for the measurement of the key parameter photoluminescence quantum yield f.1 f equals the number of emitted per number of absorbed photons. This is particularly relevant for increasingly used fluorescence imaging in the short wave-infrared region (SWIR) ≥ 900 nm providing deeper penetration depths, a better image resolution, and an improved signal-to-noise or tumor-to-background ratio.2, 3 However, spectroscopic measurements in the SWIR are more challenging and require specific calibrations and standards. T2 - EMIM 2021 CY - Göttingen, Germany DA - 24.08.2021 KW - Fluorescence KW - Optical probe KW - Dye KW - Photophysics KW - Quantum yield KW - Mechanism KW - NIR KW - SWIR KW - Imaging KW - Reference material KW - Reliability KW - Nano KW - Particle KW - Method KW - Quality assurance PY - 2021 AN - OPUS4-53233 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Altmann, Korinna A1 - Hodoroaba, Vasile-Dan T1 - CUSP inter-laboratory comparisons N2 - In this breakout session first, an introduction is given on the planning and organisation of an inter-laboratory comparison (ILC) under the pre-standardisation plattform VAMAS within the newly formed technical working area TWA 45 Micro and Nano Plastics in the Environment. An update with the ILCs on micro- and nanoplastic performed so far is also given. In the third part, the requirements for a reference materials are presented. The needs from the different H2020 micro- and nanoplastic projects are collected and compiled in an ILC matrix for joint activities as the next steps. T2 - The European Research Cluster to Understand the Health Impact of Micro- and Nanoplastics (CUSP) Launching Event CY - Online meeting DA - 10.06.2021 KW - Microplastic KW - Nanoplastic KW - Inter-laboratory comparison KW - VAMAS KW - Reference material PY - 2021 AN - OPUS4-52808 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Abram, Sarah-Luise T1 - Monodisperse iron oxide nanoparticles as reference material candidate for particle size measurements N2 - In order to utilize and rationally design materials at the nanoscale the reliable characterization of their physico-chemical properties is highly important, especially with respect to the assessment of their environmental or biological impact. Furthermore, the European Commission’s REACH Regulations require the registration of nanomaterials traded in quantities of at least 1 ton. Powders or dispersions where 50% (number distribution) of the constituent particles have sizes ≤ 100 nm in at least one dimension are defined as nanomaterials. This creates a need for industrial manufacturers and research or analytical service facilities to reliably characterize potential nanomaterials. Currently, BAM is developing reference nanoparticles, which shall expand the scarce list of worldwide available nano reference materials certified for particle size distribution and will also target other key parameters like shape, structure, porosity or functional properties. In this respect, materials like iron oxide or titanium dioxide are considered as candidates to complement the already available silica, Au, Ag, and polystyrene reference nanoparticles. The thermal decomposition of iron oleate precursors in high boiling organic solvents can provide large quantities of iron oxide nanoparticles that can be varied in size and shape.[1, 2] The presence of oleic acid or other hydrophobic ligands as capping agents ensures stable dispersion in nonpolar solvents. Such monodisperse, spherical particles were synthesized at BAM and pre-characterized by electron microscopy (TEM, SEM including the transmission mode STEM-in-SEM) and dynamic light scattering comparing cumulants analysis and frequency power spectrum. 1. REACH regulations and nanosafety concerns create a strong need for nano reference materials with diverse properties. 2. Iron oxide nanoparticles are under development as new candidate reference material at BAM. 3. Narrow particle size distribution confirmed by light scattering and electron microscopy. T2 - Nanosafety 2020 CY - Online meeting DA - 05.10.2020 KW - Iron oxide nanoparticles KW - Reference material KW - Particle size KW - Electron microscopy KW - Nanoplattform PY - 2020 AN - OPUS4-52774 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hodoroaba, Vasile-Dan T1 - Other than spherical/monodisperse Towards real world NPs as candidate reference materials for traceable size measurements N2 - By far most of the current nanoparticle (NP) research is dealing with (quasi-) spherical and/or monodisperse particles. However, many NPs used in industrial applications are rather aspherical and polydisperse. This inhomogeneity considerably hampers their characterization and, particularly, the accurate determination of the nanoparticle size. In order to overcome this problem and to promote the availability of standardized size measurement methods, it is crucial to develop and establish (candidate) reference materials with inhomogeneous size (distribution), aspherical shape as well as agglomerated or aggregated particles. Therefore, a new set of NPs including Au-, SiO2 , and TiO2-particles is investigated. The range of properties comprises polydisperse spherical, bimodal spherical, rod-like, acicular, bipyramidal, sheet-like as well as cubic NPs. With respect to a good traceability of the measurements, size and size distributions of the candidate reference materials are determined using microscopic methods like scanning electron microscopy (SEM), transmission electron microscopy (TEM), scanning electron microscopy in transmission mode (STEM-in-SEM), atomic force microscopy (AFM) as well as small angle X-ray scattering (SAXS) as an ensemble technique. The development of protocols for sample preparation is of particular importance to obtain a homogeneous dispersion of the NPs on a substrate. Further, approaches for signal modelling for all the methods above are being developed. The initiation of two VAMAS (www.vamas.org/twa34/index.html) inter-laboratory comparisons on bipyramidal titania and bimodal silica with different modal concentration ratios will be also highlighted. T2 - E-MRS Spring Meeting 2021 CY - Online meeting DA - 31.05.2021 KW - Nanoparticles KW - Particle size distribution KW - Imaging KW - Traceability KW - Reference material PY - 2021 AN - OPUS4-52764 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin T1 - DNA based Reference Materials: In Biodosimetry and Pharmaceutical Quality Control N2 - Applications of plasmid DNA base reference materials in dosimetry and pharmaceutical research. T2 - Physical and Chemical Analysis of Polymers seminar CY - Online meeting DA - 29.03.2021 KW - Analytic KW - Certification KW - DNA KW - Dosimetry KW - Homogeneity KW - Quality testing KW - Reference material KW - Referenzmaterialien KW - Stability KW - Dose KW - Radiation KW - Pharmacy KW - Electrohpresis PY - 2021 AN - OPUS4-52361 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hahn, Marc Benjamin T1 - Reference Materials at BAM N2 - A introduction into reference materials, the certification process and brief over current reference projects at BAM is given. T2 - AK-Postdoc seminar CY - BAM Berlin, Germany DA - 02.02.2021 KW - Referenzmaterialien KW - Reference material KW - Homogeneity KW - Stability KW - Quality testing KW - Analytic KW - DNA KW - Dosimetry KW - Certification PY - 2021 AN - OPUS4-52060 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Relative and Absolute Methods for Measuring Photoluminescence Quantum Yields of UV/vis/NIR Emitters N2 - One of the key spectroscopic performance parameters of molecular and particulate emitters is the photoluminescence quantum yield (PL QY) that provides a direct measure for the number of emitted per absorbed photons. This triggered the interest in methods suitable for measuring this property for emitters in various environments in the UV/vis/NIR and above 1000 nm as well as on the ensemble and single emitter level. Moreover, for nonlinear emitters like lanthanide-based upconversion nanocrystals methods including instrumentation for power density-dependent PL QY studies are required. An overview of the research activities in Division Biophotonics of BAM is given and suitable relative and absolute methods for the deter-mination of PL QY of organic dyes and different types of application-relevant nanomaterials in dispersion and in the solid state are presen-ted. This covers also the design and calibration of integrating sphere setups, achievable uncertainties, and candidates for PL QY reference materials. T2 - OSRAM Veranstaltung CY - Regensburg, Germany DA - 09.01.2019 KW - Quantum yield KW - Calibration KW - Reference material KW - Uncertainty KW - Absolute fluorometry KW - Integrating sphere spectroscopy KW - NIR KW - IR KW - Fluorescence KW - Nanoparticle KW - Dye PY - 2019 AN - OPUS4-47263 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Recknagel, Sebastian T1 - Non-metals in inorganic reference materials N2 - The analysis of non-metals normally is carried out using elemental analysers which require reference material for calibration. In the lecture the CRM-program of BAM suitable for non-metal-analysis is presented. There are CRMs available with non-metal contents in the low ppm up to the high percent region. T2 - CETAMA 2018 CY - Paris, France DA - 27.11.2018 KW - CRM KW - Non-metals KW - Carbon KW - Sulfur KW - Oxygen KW - Nitrogen KW - Hydrogen KW - Reference material PY - 2018 AN - OPUS4-46968 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Needs and Tools Standardization of Fluorescence N2 - Photoluminescence techniques are amongst the most widely used tools in the life sciences, with new and exciting applications in medical diagnostics and molecular imaging continuously emerging. Advantages include their comparative ease of use, unique sensitivity, non-invasive character, and potential for multiplexing, remote sensing, and miniaturization. General drawbacks are, however, signals, that contain unwanted wavelength- and polarization contributions from instrument-dependent effects, which are also time-dependent due to aging of instrument-components, and difficulties to measure absolute fluorescence intensities. Moreover, scattering samples require special measurement geometries and emerging optical Reporters with emission > 1000 nm strategies for reliable measurements in the second diagnostic window or short wavelength infrared (SWIR) for the comparison of material performance and the rational design of new fluorophores with improved properties. Here, we provide a brief overview over different types of fluorescence standards for instrument calibration and performance control. Also, strategies to versatile method-adaptable liquid and solid fluorescence standards for different fluorescence parameters and applications are presented. This includes spectral emission standards for the traceable determination of the wavelengthdependent spectral responsivity (emission correction curve) of fluorescence measuring devices in the UV/vis/NIR, solid multi-emitter systems for daily instrument performance control, and new standards for the relative determination of the fluorescence quantum yield, the key performance parameter of all emitters. The latter standards enable also performance Control of increasingly used integrating sphere setups. T2 - 15th International Symposium on Biological and Environmental Reference Materials CY - Berlin, Germany DA - 23.09.2018 KW - Fluorescence KW - Reference material KW - Quality assurance KW - Standardization KW - Quantum yield KW - Emission standard KW - Dye KW - Glass KW - Calibration slide KW - Instrument performance validation PY - 2018 AN - OPUS4-46390 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Vogl, Jochen T1 - Isotope dilution mass spectrometry applied as primary method of measurement with examples from the ENVCRM project N2 - The presentation describes the application of isotope dilution mass spectrometry as a primary method of measurement with all Advantages and disadvantges. This is exempflified for the candidate reference materials within the EnvCRM Project. T2 - Workshop Matrix Reference Materials for Environmental Analysis CY - Gebze, Turkey DA - 16.05.2018 KW - Reference material KW - Soil KW - Heavy metals PY - 2018 AN - OPUS4-45896 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Hodoroaba, Vasile-Dan T1 - Shape controlled TiO2 nanoparticles as candidates for nano-CRM’s – an ISO case study N2 - Extraction of true, 3D shape (and size) of non-spherical nanoparticles (NPs) is associated with errors by conventional 2D electron microscopy using projection images. Significant efforts within the ISO technical committee TC 229 ‘Nanotechnologies’ are aimed at establishing accurate TEM and SEM measurement of NP size and shape as robust, standard procedures. Study groups have been organizing inter-laboratory comparisons on well-selected NP systems according to the market needs, such as aggregated titania nano-powder for which size and shape distribution of primary crystallites of irregular shape must be measured accurately. To be noticed is e. g. the fact that the measurement procedure allows only manual selection of the particles clearly distinguishable for analysis as well as manual definition of the contour of the imaged NPs. An inter-laboratory exercise on titania NPs (pure anatase, grown by hydrothermal synthesis) of well-defined non-spherical shape, i.e. bipyramidal has been recently started within ISO/TC 229 under similar conditions as for the irregular shaped titania. Overlapped particles were allowed to be considered, as long as they are clearly distinguishable. One decisive NP selection criterion was to analyze only those NPs with a roundness value below 0.7, i.e. the NPs laying on the support foil and, hence, with projection areas clearly deviating from perfect circles (R=1). The overall evaluation (for 15 labs) of the size descriptors (area, Feret, minFeret, perimeter) and shape descriptors (aspect ratio, roundness, compactness, extent) by analysis of variance is just to be finished and included in ISO/WD 21363 Nanotechnologies -- Protocol for particle size distribution by transmission electron microscopy. T2 - NanoWorkshop 2018 (Workshop on reference nanomaterials, current situation and needs: development, measurement, standardization) CY - Berlin, Germany DA - 14.05.2018 KW - Titanium oxide KW - Nanoparticles KW - Shape-controlled KW - Electron microscopy KW - Reference material PY - 2018 AN - OPUS4-44996 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Theory of the Photoluminescence Quantum Yield and its Measurement for Different Emitters N2 - Mandatory for the comparison of different emitter classes and the rational design of the next generation of molecular and nanoscale reporters are reliable and quantitative photoluminescence measurements. This is of special relevance for all fluorescence applications in the life and material sciences. In the following, proccedures for the determination of this spectroscopic key parameter are presented including material-specific effects related to certain emitters T2 - COST 2017 CY - Turku, Finland DA - 03.04.2017 KW - Instrument calibration KW - Standard KW - Flourescence KW - Reference material KW - Absolute fluorometry KW - Integrating sphere spectroscopy KW - NIR KW - IR KW - Photophysics KW - Quantum yield KW - Dye PY - 2017 AN - OPUS4-43175 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER - TY - CONF A1 - Resch-Genger, Ute T1 - Research and development in material and life sciences and quality assurance at BAM N2 - Research and development activities at BAM are presented with Special Focus on bioanalysis and biophotonics. This includes Topics from the Focus Areas Material, Environment, and Analytical Sciences. Also, Job opportunities at BAM are emphasized. T2 - MPI CY - Göttingen, Germany DA - 26.10.2017 KW - Analytics KW - Materials KW - Fluorometry KW - Sensors KW - Biophotonics KW - Microbiology KW - Reference material KW - Standard KW - Calibration KW - Nanoparticle PY - 2017 AN - OPUS4-43132 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -