65156 2025 eng lecture 0 -- -- -- The industrial sector faces challenges in ensuring safety and efficiency of operation and maintenance tasks (OMT). These tasks involve manual interventions such as equipment inspections or sample extractions. OMT require workers to communicate with control rooms and follow strict operational protocols while managing physical and cognitive loads. Common challenges include safety risks, the difficulty of using safety gear, limited accessibility to information, inefficient communication, and high (human) error rates. While chemical plants traditionally rely on paper-based workflows to tackle the mentioned challenges, we present an approach that leverages digital checklists to model workflows, integrating them with industrial documentation and process automation systems. We combine these elements into contextualized workflows that are deployed in a Mixed Reality (MR) application allowing to support personnel with hands-free execution, real-time verification, and an MR-based human-machine interface (HMI). This integration enhances safety through automated system checks and MR-guided validation while reducing the cognitive load on personnel. We present an MR prototype based on a vacuum distillation sampling procedure that grants access to documentation, interfaces with process control systems, and manages workflows dynamically. Compared to conventional industrial checklists, our approach reduces errors by combining gamification, IT-based validation, and immersive task visualization while enabling hands-free task execution. As future work, we envision a generalized framework for rapidly incorporating new tasks, enhancing adaptability in industrial environments. This research paves the way for standardized MR solutions in chemical plant operations, ultimately improving efficiency, safety, and workforce engagement. Process Engineering and Materials Technology (PEMT) Frankfurt am Main, Germany 10.11.2025 11.11.2025 0 publish false true Hernán Darío Muñoz Gil eng uncontrolled Safety eng uncontrolled Mixed Reality eng uncontrolled Operation & Maintenance eng uncontrolled Digital workflows eng uncontrolled Process control system Chemische Verfahrenstechnik 2 Prozess- und Anlagensicherheit 2.2 Prozesssimulation Chemie und Prozesstechnik Datei im Netzwerk der BAM verfügbar ("Closed Access") Präsentation Anlagensicherheit und Prozesssimulation