64717 2025 eng lecture 0 -- -- -- Accurate analysis of microplastics is based on validated methods and the use of standardized protocols. Therefore, reference materials are essential to determine recovery rates and optimise the existing workflows. The reference materials should mimic the reality in terms of particle properties and concentration and are intended for a special use. The Quality-by-Design approach helps to select the users need and defines a target product profile with mandatory and desired particle properties. We will address different reference material top-down production processes with their limits and challenges for production of materials varying in size ranges of micro- and nanoplastics. OECD Workshop on Nanoplastics Paris, France 12.11.2025 0 publish false true Korinna Altmann eng uncontrolled Microplastics eng uncontrolled Reference materials eng uncontrolled Nanoplastics eng uncontrolled Quality-by-Design Ingenieurwissenschaften und zugeordnete Tätigkeiten Sanitär- und Kommunaltechnik; Umwelttechnik 6 Materialchemie 6.5 Synthese und Streuverfahren nanostrukturierter Materialien Umwelt Umwelt-Material-Interaktionen Material Datei im Netzwerk der BAM verfügbar ("Closed Access") Präsentation Advanced Materials