63339 2025 eng poster 0 -- -- -- Engineered nanoparticles (NPs) with various chemical compositions and surface functionalities are routinely fabricated for industrial applications such as medical diagnostics, drug delivery, sensing, catalysis, energy conversion and storage, optoelectronics, and information storage. NP function, interaction with biological species, and environmental fate are largely determined by surface functionalities. Reliable, reproducible, and standardized surface characterization methods are therefore vital for quality control of NPs, and mandatory to meet increasing concerns regarding their safety. Also, industry, international standardization organizations, regulatory agencies, and policymakers need validated and standardized measurement methods and reference materials. However, methodologies for determining NP surface properties, including the amount, chemical composition, and homogeneity of surface functionalities and coatings are largely non-standardized. Suitable methods for determining surface functionalities on ligand-stabilized core and core/shell NPs include advanced techniques such as traceable quantitative nuclear magnetic resonance (qNMR) as well as X-ray electron spectroscopy (XPS) and time of flight secondary ion mass spectrometry (ToF-SIMS), and simpler optical and electrochemical methods. The latter less costly methods are often used by SMEs, e.g., for quality control. To validate methods, establish measurement uncertainties, test reference materials, and produce reference data, international interlaboratory comparisons (ILC) on NP surface functionalization measurements are required and well characterized test and reference nanomaterials providing benchmark values.[1] These needs are addressed by the recently started European metrology project SMURFnano involving 12 partners from different National Metrology Institutes, designated institutes, and research institutes, two university groups as well as one large company and one SME producing NPs. This project as well as first results derived from the development of test and reference materials with a well characterized surface chemistry and ongoing interlaboratory comparisons will be presented. eMRS Strasbourg, France 27.05.2025 31.05.2025 publish false true Ute Resch-Genger eng uncontrolled Quality assurance eng uncontrolled Fluorescence eng uncontrolled Nano eng uncontrolled Particle eng uncontrolled Synthesis eng uncontrolled Silica eng uncontrolled Upconversion nanoparticles eng uncontrolled Optical assay eng uncontrolled qNMR eng uncontrolled Surface analysis eng uncontrolled Ligand eng uncontrolled Quantification eng uncontrolled Functional group eng uncontrolled XPS eng uncontrolled ToF-SIMS eng uncontrolled Polymer particle eng uncontrolled Surface modification eng uncontrolled Potentiometry eng uncontrolled Metrology eng uncontrolled Method eng uncontrolled Validation eng uncontrolled ILC Analytische Chemie Ingenieurwissenschaften und zugeordnete Tätigkeiten 1 Analytische Chemie; Referenzmaterialien 1.2 Biophotonik 6 Materialchemie 6.1 Oberflächen- und Dünnschichtanalyse Umwelt Material Chemie und Prozesstechnik Chemische Charakterisierung und Spurenanalytik Datei im Netzwerk der BAM verfügbar ("Closed Access") Präsentation Advanced Materials