45475 2018 eng poster 0 -- -- -- Diclofenac (DCF) is a widely used drug against fever, inflammation, pain, and rheumatic diseases. An average of 70 % of the ingested diclofenac is excreted in the urine. Thus, 63 tons per year are introduced into the water cycle in Germany. Due to insufficient removal of diclofenac in wastewater treatment plants, residues of diclofenac can be found in surface water and sometimes in drinking water. In order to establish an immunoassay, an anti-DCF antibody was required. Some antibody developments have been reported, based on an immunogen resulting from direct coupling of diclofenac to proteins via the carboxylic function. Finally, we used a monoclonal antibody, clone F01G21. Tag der Biotechnologie der TU Berlin Berlin, Germany 13.07.2018 13.07.2018 Stephan Schmidt deu uncontrolled Wasserproben deu uncontrolled Arzneimittel deu uncontrolled Antikörper deu uncontrolled ELISA Analytische Chemie Sanitär- und Kommunaltechnik; Umwelttechnik Datei im Netzwerk der BAM verfügbar ("Closed Access") Präsentation