40409 2017 eng 76 81 526 article Elsevier B.V. 1 -- -- -- The report on the results of an in vitro digestion study of silver nanoparticles in presence and absenceof food. The particles were poly(acrylic acid) stabilized ultra-small silver nanoparticles with a radius of 3.1 nm and a relative size distribution width of 0.2. As food components oil, starch, skimmed milk powderand a mixture thereof were chosen. Aggregation of the particles was quantified with small-angle X-rayscattering in terms of log-normal radii distributions. Complete aggregation of the primary particles wasdetermined in the absence of food. In contrast, the presence of oil and starch initiates a disaggregationin the intestine. Only small aggregates of 6 nm radii and aggregation numbers of 7 were found in thepresence of milk powder. It prevents primary particles from etching in the gastric and intestinal juice.Our results indicate that the silver nanoparticles can pass the digestion process in a nanoscale form butundergo a strong and food-dependent transformation in their state of aggregation. Colloids and Surfaces A: Physicochemical and Engineering Aspects 10.1016/j.colsurfa.2016.08.013 urn:nbn:de:kobv:b43-404099 0927-7757 1873-4359 07.07.2017 Creative Commons - Namensnennung 3.0 Claudia Kästner Dajana Lichtenstein Alfonso Lampen Andreas Thünemann eng uncontrolled Small-angle X-ray scattering eng uncontrolled SAXS Analytische Chemie Ingenieurwissenschaften und zugeordnete Tätigkeiten Verlagsliteratur Datei für die Öffentlichkeit verfügbar ("Open Access") Wissenschaftliche Artikel der BAM Bundesanstalt für Materialforschung und -prüfung (BAM) https://opus4.kobv.de/opus4-bam/files/40409/Monitoring the fate of small silver nanoparticles during artificial digestion.pdf