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  <doc>
    <id>63489</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>10630</pageFirst>
    <pageLast>10717</pageLast>
    <pageNumber/>
    <edition/>
    <issue>11</issue>
    <volume>19</volume>
    <type>article</type>
    <publisherName>ACS Publications</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Interfacing with the Brain: How Nanotechnology Can Contribute</title>
    <abstract language="eng">Interfacing artificial devices with the human brain is the central goal of neurotechnology. Yet, our imaginations are often limited by currently available paradigms and technologies. Suggestions for brain−machine interfaces have changed over time, along with the available technology.&#13;
Mechanical levers and cable winches were used to move parts of the brain during the mechanical age. Sophisticated electronic wiring and remote control have arisen during the electronic age, ultimately leading to plug-and-play computer interfaces. Nonetheless, our brains are so complex that these visions, until recently, largely remained unreachable dreams. The general problem, thus far, is that most of our technology is mechanically and/or electrically engineered, whereas the brain is a living, dynamic entity. As a result, these worlds are difficult to interface with one another. Nanotechnology, which encompasses engineered solid-state objects and integrated circuits, excels at small length scales of single to a few hundred nanometers and, thus, matches the sizes of biomolecules, biomolecular assemblies, and parts of cells. Consequently, we envision nanomaterials and nanotools as opportunities to interface with the brain in alternative ways. Here, we review the existing literature on the use of nanotechnology in brain−machine interfaces and look forward in discussing perspectives and limitations based on the authors’ expertise across a range of complementary disciplines from neuroscience, engineering, physics, and chemistry to biology and medicine, computer science and mathematics, and social science and jurisprudence. We focus on nanotechnology but also include information from related fields when useful and complementary.</abstract>
    <parentTitle language="eng">ACS Nano</parentTitle>
    <identifier type="doi">10.1021/acsnano.4c10525</identifier>
    <identifier type="issn">1936-086X</identifier>
    <identifier type="urn">urn:nbn:de:kobv:b43-634893</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="date_peer_review">26.06.2025</enrichment>
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    <enrichment key="opus.urn.autoCreate">true</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>A. A. A. Ahmed</author>
    <author>N. Alegret</author>
    <author>B. Almeida</author>
    <author>R. Alvarez-Puebla</author>
    <author>A. M. Andrews</author>
    <author>L. Ballerini</author>
    <author>J. J. Barrios-Capuchino</author>
    <author>C. Becker</author>
    <author>R. H. Blick</author>
    <author>S. Bonakdar</author>
    <author>I. Chakraborty</author>
    <author>X. Chen</author>
    <author>J. Cheon</author>
    <author>G. Chilla</author>
    <author>A. L. C. Conceicao</author>
    <author>J. Delehanty</author>
    <author>M. Dulle</author>
    <author>A. L. Efros</author>
    <author>M. Epple</author>
    <author>M. Fedyk</author>
    <author>N. Feliu</author>
    <author>M. Feng</author>
    <author>R. Fernandez-Chacon</author>
    <author>I. Fernandez-Cuesta</author>
    <author>N. Fertig</author>
    <author>S. Förster</author>
    <author>J. A. Garrido</author>
    <author>M. George</author>
    <author>A. H. Guse</author>
    <author>N. Hampp</author>
    <author>J. Harberts</author>
    <author>J. Han</author>
    <author>H. R. Heekeren</author>
    <author>U. G. Hofmann</author>
    <author>M. Holzapfel</author>
    <author>H. Hosseinkazemi</author>
    <author>Y. Huang</author>
    <author>P. Huber</author>
    <author>T. Hyeon</author>
    <author>S. Ingebrandt</author>
    <author>M. Ienca</author>
    <author>A. Iske</author>
    <author>Y. Kang</author>
    <author>G. Kasieczka</author>
    <author>D.-H. Kim</author>
    <author>K. Kostarelos</author>
    <author>J.-H. Lee</author>
    <author>K.-W. Lin</author>
    <author>S. Liu</author>
    <author>X. Liu</author>
    <author>Y. Liu</author>
    <author>C. Lohr</author>
    <author>V. Mailänder</author>
    <author>L. Maffongelli</author>
    <author>S. Megahed</author>
    <author>A. Mews</author>
    <author>M. Mutas</author>
    <author>L. Nack</author>
    <author>N. Nakatsuka</author>
    <author>T. G. Oertner</author>
    <author>A. Offenhäusser</author>
    <author>M. Oheim</author>
    <author>B. Otange</author>
    <author>F. Otto</author>
    <author>E. Patrono</author>
    <author>B. Peng</author>
    <author>A. Picchiotti</author>
    <author>F. Pierini</author>
    <author>M. Pötter-Nerger</author>
    <author>M. Pozzi</author>
    <author>A. Pralle</author>
    <author>M. Prato</author>
    <author>B. Qi</author>
    <author>P. Ramos-Cabrer</author>
    <author>Ute Resch-Genger</author>
    <author>N. Ritter</author>
    <author>M. Rittner</author>
    <author>S. Roy</author>
    <author>F. Santoro</author>
    <author>N. W. Schuck</author>
    <author>F. Schulz</author>
    <author>E. Seker</author>
    <author>M. Skiba</author>
    <author>M. Sosniok</author>
    <author>H. Stephan</author>
    <author>R. Wang</author>
    <author>T. Wang</author>
    <author>Karl David Wegner</author>
    <author>P. S. Weiss</author>
    <author>M. Xu</author>
    <author>C. Yang</author>
    <author>S. S. Zargarin</author>
    <author>Y. Zeng</author>
    <author>Y. Zhou</author>
    <author>D. Zhu</author>
    <author>R. Zierold</author>
    <author>W. J. Parak</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Nanoneuro interface</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Brain-on-a-chip</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Nanostructured interface</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Electrode arrays</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Neuro-implants</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Advanced nanomaterials</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Quality assurance</value>
    </subject>
    <collection role="ddc" number="620">Ingenieurwissenschaften und zugeordnete Tätigkeiten</collection>
    <collection role="ddc" number="628">Sanitär- und Kommunaltechnik; Umwelttechnik</collection>
    <collection role="institutes" number="">1 Analytische Chemie; Referenzmaterialien</collection>
    <collection role="institutes" number="">1.2 Biophotonik</collection>
    <collection role="themenfelder" number="">Umwelt</collection>
    <collection role="themenfelder" number="">Material</collection>
    <collection role="literaturgattung" number="">Verlagsliteratur</collection>
    <collection role="fulltextaccess" number="">Datei für die Öffentlichkeit verfügbar ("Open Access")</collection>
    <collection role="unnumberedseries" number="">Wissenschaftliche Artikel der BAM</collection>
    <collection role="themenfelder" number="">Advanced Materials</collection>
    <collection role="themenfelder" number="">Sensorik</collection>
    <thesisPublisher>Bundesanstalt für Materialforschung und -prüfung (BAM)</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-bam/files/63489/QD Neuron_ASC Nano_2025.pdf</file>
  </doc>
  <doc>
    <id>54347</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>8</pageLast>
    <pageNumber/>
    <edition/>
    <issue>1</issue>
    <volume>8</volume>
    <type>article</type>
    <publisherName>Springer</publisherName>
    <publisherPlace>Berlin</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Quantitative considerations about the size dependence of cellular entry and excretion of colloidal nanoparticles for different cell types</title>
    <abstract language="eng">Most studies about the interaction of nanoparticles (NPs) with cells have focused on how the physicochemical properties of NPs will influence their uptake by cells. However, much less is known about their potential excretion from cells. However, to control and manipulate the number of NPs in a cell, both cellular uptake and excretion must be studied quantitatively. Monitoring the intracellular and extracellular amount of NPs over time (after residual noninternalized NPs have been removed) enables one to disentangle the influences of cell proliferation and exocytosis, the major pathways for the reduction of NPs per cell. Proliferation depends on the type of cells, while exocytosis depends in addition on properties of the NPs, such as their size. Examples are given herein on the role of these two different processes for different cells and NPs.</abstract>
    <parentTitle language="eng">ChemTexts</parentTitle>
    <identifier type="doi">10.1007/s40828-021-00159-6</identifier>
    <identifier type="urn">urn:nbn:de:kobv:b43-543476</identifier>
    <identifier type="issn">2199-3793</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="date_peer_review">16.02.2022</enrichment>
    <enrichment key="RelatedIdentifier">https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/55451</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Y. Kang</author>
    <author>L. M. Nack</author>
    <author>Y. Liu</author>
    <author>B. Qi</author>
    <author>Y. Huang</author>
    <author>Z. Liu</author>
    <author>I. Chakraborty</author>
    <author>F. Schulz</author>
    <author>A. A. A. Ahmed</author>
    <author>M. C. Poveda</author>
    <author>F. Hafizi</author>
    <author>S. Roy</author>
    <author>M. Mutas</author>
    <author>M. Holzapfel</author>
    <author>C. Sanchez-Cano</author>
    <author>Karl David Wegner</author>
    <author>N. Feliu</author>
    <author>W. J. Parak</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Cell proliferation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Exocytosis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Gold nanoparticles</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Quantum dots</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Fluorescence</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Uptake studies</value>
    </subject>
    <collection role="ddc" number="628">Sanitär- und Kommunaltechnik; Umwelttechnik</collection>
    <collection role="institutes" number="">1 Analytische Chemie; Referenzmaterialien</collection>
    <collection role="institutes" number="">1.2 Biophotonik</collection>
    <collection role="themenfelder" number="">Umwelt</collection>
    <collection role="themenfelder" number="">Umwelt-Material-Interaktionen</collection>
    <collection role="literaturgattung" number="">Verlagsliteratur</collection>
    <collection role="fulltextaccess" number="">Datei für die Öffentlichkeit verfügbar ("Open Access")</collection>
    <collection role="unnumberedseries" number="">Wissenschaftliche Artikel der BAM</collection>
    <thesisPublisher>Bundesanstalt für Materialforschung und -prüfung (BAM)</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-bam/files/54347/Kang_Chemtexts_QuantitativeConsiderations.pdf</file>
  </doc>
  <doc>
    <id>55451</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>2</pageLast>
    <pageNumber/>
    <edition/>
    <issue>17</issue>
    <volume>8</volume>
    <type>corrigendum</type>
    <publisherName>Springer</publisherName>
    <publisherPlace>Berlin</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Correction to: Quantitative considerations about the size dependency for cellular entry and excretion of colloidal nanoparticles for different cell types</title>
    <abstract language="eng">We regret to inform that the labels "NPs which remain in endosomes/lysosomes" and "exocytosed NPs" had been erroneously swapped in the sketch on the right side in Figure 2. The corrected Fig. 2 is displayed below. WJP apologizes for this error.</abstract>
    <parentTitle language="eng">ChemTexts</parentTitle>
    <identifier type="doi">10.1007/s40828-022-00168-z</identifier>
    <identifier type="urn">urn:nbn:de:kobv:b43-554519</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="RelatedIdentifier">https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/54347</enrichment>
    <licence>Creative Commons - CC BY-NC - Namensnennung - Nicht kommerziell 4.0 International</licence>
    <author>Y. Kang</author>
    <author>L. Nack</author>
    <author>Y. Liu</author>
    <author>B. Qi</author>
    <author>Y. Huang</author>
    <author>Z. Liu</author>
    <author>I. Chakraborty</author>
    <author>F. Schulz</author>
    <author>A. A. Ahmed</author>
    <author>M. C. Poveda</author>
    <author>F. Hafizi</author>
    <author>S. Roy</author>
    <author>M. Mutas</author>
    <author>M. Holzapfel</author>
    <author>C. Sanchez-Cano</author>
    <author>Karl David Wegner</author>
    <author>N. Feliu</author>
    <author>W. J. Parak</author>
    <collection role="ddc" number="628">Sanitär- und Kommunaltechnik; Umwelttechnik</collection>
    <collection role="literaturgattung" number="">Verlagsliteratur</collection>
    <collection role="fulltextaccess" number="">Datei für die Öffentlichkeit verfügbar ("Open Access")</collection>
    <thesisPublisher>Bundesanstalt für Materialforschung und -prüfung (BAM)</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-bam/files/55451/Kang2022_Article_CorrectionToQuantitativeConsid.pdf</file>
  </doc>
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