26149
2012
deu
lecture
0
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Results of the 2011 Ethyl Glucuronide and FAEE Proficiency Test
17th Meeting of the Society of Hair Testing
28894
17th Meeting of the Society of Hair Testing
Toronto, Canada
2012-06-25
2012-06-28
0
F. Sporkert
Weder Datei noch physisches Exemplar vorhanden ("No Access")
Präsentation
44881
2018
eng
67
71
288
article
Elsevier
1
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The determination of ethyl glucuronide in hair: Experiences from nine consecutive interlaboratory comparison rounds
The increasing request for hair ethyl glucuronide (HEtG) in alcohol consumption monitoring according to cut-off levels set by the Society of Hair Testing (SoHT) has triggered a proficiency testing program based on interlaboratory comparisons (ILC). Here, the outcome of nine consecutive ILC rounds organised by the SoHT on the determination of HEtG between 2011 and 2017 is summarised regarding interlaboratory reproducibility and the influence of procedural variants. Test samples prepared from cut hair (1 mm) with authentic (in-vivo incorporated) and soaked (in-vitro incorporated) HEtG concentrations up to 80 pg/mg were provided for 27–35 participating laboratories. Laboratory results were evaluated according to ISO 5725-5 and provided robust averages and relative reproducibility standard deviations typically between 20 and 35% in reasonable accordance with the prediction of the Horwitz model. Evaluation of results regarding the analytical techniques revealed no significant differences between gas and liquid chromatographic methods In contrast, a detailed evaluation of different sample preparations revealed significantly higher average values in case when pulverised hair is tested compared to cut hair. This observation was reinforced over the different ILC rounds and can be attributed to the increased acceptance and routine of hair pulverisation among laboratories. Further, the reproducibility standard deviations among laboratories performing pulverisation were on average in very good agreement with the prediction of the Horwitz model. Use of sonication showed no effect on the HEtG extraction yield.
Forensic Science International
10.1016/j.forsciint.2018.04.025
0379-0738
1872-6283
14.05.2018
Roland Becker
F. Sporkert
I. Lô
M. Baumgartner
eng
uncontrolled
Ethyl glucuronide
eng
uncontrolled
Interlaboratory comparison
eng
uncontrolled
Proficiency testing
eng
uncontrolled
Society of hair testing
eng
uncontrolled
Reproducibility
eng
uncontrolled
Pulverization
Analytische Chemie
1 Analytische Chemie; Referenzmaterialien
1.7 Organische Spuren- und Lebensmittelanalytik
Chemie und Prozesstechnik
Chemische Charakterisierung und Spurenanalytik
Verlagsliteratur
Datei im Netzwerk der BAM verfügbar ("Closed Access")