TY  - JOUR
A1  - Capitain, C.
A1  - Schüßler, M.
A1  - Bugsel, B.
A1  - Zweigle, J.
A1  - Vogel, Christian
A1  - Leube, Peter
A1  - Zwiener, C.
T1  - Implementation of matrix-matched semiquantification of PFAS in AFFF-contaminated soil
JF  - Environmental science and technology
N2  - This study presents a novel semiquantification approach for nontarget screening (NTS), combining matrix-matched calibration and ionization class-specific average calibration curves (ACCs) to address the lack of analytical reference standards for most per- and polyfluoroalkyl substances (PFAS). Ionization class-specific ACCs for carboxylic and sulfonic acids, sulfonamides, and cationic PFAS result in high accuracy, with median absolute accuracy quotients below 2.27×. The approach was applied to soil impacted by aqueous film-forming foam (AFFF) contamination. A total of 96 tentatively identified PFAS were semiquantified in addition to 28 quantified compounds based on available standards. Semiquantified concentrations exceeded those of target analytes, demonstrating the critical role of this method in capturing broader PFAS contamination. In this case, validation against extractable organofluorine (EOF) showed a 102% closed mass balance. The innovative approach not only enables comprehensive PFAS contamination assessment in complex matrices but also expands the scope of the NTS for environmental monitoring, remediation, and risk assessment of AFFF-contaminated sites.
KW  - Per- and polyfluoroalkyl substances (PFAS)
KW  - Contaminated soil
KW  - Non-targeted analysis
KW  - Combustion ion chromatography
PY  - 2025
UR  - https://nbn-resolving.org/urn:nbn:de:kobv:b43-629445
DO  - https://doi.org/10.1021/acs.est.4c14255
SN  - 1520-5851
VL  - 59
IS  - 14
SP  - 7338
EP  - 7347
PB  - American Chemical Society (ACS)
CY  - Columbus, Ohio
AN  - OPUS4-62944
LA  - eng
AD  - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany
ER  -