TY - JOUR A1 - Obaton, A-F. A1 - Fain, J. A1 - Djemaï, M. A1 - Meinel, Dietmar A1 - Léonard, Fabien A1 - Mahé, E. A1 - Lécuelle, B. A1 - Fouchet, J-J. A1 - Bruno, Giovanni T1 - In vivo XCT bone characterization of lattice structured implants fabricated by additive manufacturing T2 - Heliyon N2 - Several cylindrical specimens and dental implants, presenting diagonal lattice structures with different cell sizes (600, 900 and 1200 µm) were additively manufactured by selective laser melting process. Then they were implanted for two months in a sheep. After removal, they were studied by Archimedes’ method as well as X-ray computed tomography in order to assess the penetration of bone into the lattice. We observed that the additive manufactured parts were geometrically conform to the theoretical specifications. However, several particles were left adhering to the surface of the lattice, thereby partly or entirely obstructing the cells. Nevertheless, bone penetration was clearly visible. We conclude that the 900 µm lattice cell size is more favourable to bone penetration than the 1200 µm lattice cell size, as the bone penetration is 84 % for 900 µm against 54 % for 1200 µm cell structures. The lower bone penetration value for the 1200 µm lattice cell could possibly be attributed to the short residence time in the sheep. Our results lead to the conclusion that lattice implants additively manufactured by selective laser melting enable better bone integration. PB - Elsevier Limited CY - 125 London Wall London, EC2Y 5AS United Kingdom KW - Biomedical engineering KW - Dentistry KW - Medical imaging KW - X-ray computer tomography PY - 2017 UR - https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/41864 AN - OPUS4-41864 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-418648 SN - 2405-8440 IS - 3 SP - Article e00374, 1 EP - 21 AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany