TY - JOUR A1 - Arroyo-Abad, Uriel A1 - Lischka, Susanne A1 - Piechotta, Christian A1 - Mattusch, J. A1 - Reemtsma, T. T1 - Determination and identification of hydrophilic and hydrophobic arsenic species in methanol extract of fresh cod liver by RP-HPLC with simultaneous ICP-MS and ESI-Q-TOF-MS detection T2 - Food chemistry N2 - The present study was focused on the determination and identification of arsenic species in methanolic extracts of cod liver. Arsenic species were fractionated and the fractions analysed by RP-HPLC-ICP-MS coupled with ESI-Q-TOF-MS. The total concentration of arsenic in the fresh cod liver was analysed by ICP-MS to be 1.53 ± 0.02 mg As kg-1 w.w. and the extraction recovery was ca. 100% and the column recovery >93%. Besides polar inorganic and methylated arsenic species (>70%) more hydrophobic arsenic-containing fatty acids and hydrocarbons occurred. Based on the mass spectrometric data proposals for molecular structures were elaborated for 20 of the organic As species included 10 arsenic-containing fatty acids (AsFA) and an arsenic-containing hydrocarbon (AsHC) mentioned for the first time in fresh cod liver. Arsenobetaine was found as main water-soluble arsenic compound in cod liver followed by higher molecular mass arsenic-containing fatty acids and hydrocarbons. PB - Elsevier CY - Amsterdam [u.a.] ; Jena KW - Arsenic species KW - Arsenolipids KW - Marine fish KW - Cod liver KW - HPLC-ICP-MS/ESI-Q-TOF-MS PY - 2013 UR - https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/28852 AN - OPUS4-28852 SN - 0308-8146 VL - 141 IS - 3 SP - 3093 EP - 3102 AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany