TY - CONF A1 - Schwirn, K. A1 - Völker, D. A1 - Ahtianinen, J. A1 - Schmidt, Alexandra A1 - Bresch, Harald A1 - Kämpf, K. A1 - Bachmann, V. A1 - Kuhlbusch, T. A2 - Bosse, H. A2 - Buhr, E. A2 - Dziomba, T. A2 - Hodoroaba, Vasile-Dan A2 - Klein, T. A2 - Krumrey, M. T1 - OECD Test Guidelines development for chemicals safety assessment of nanomaterials T2 - PTB-Bericht F-61 - NanoWorkshop 2018: Workshop on Reference Nanomaterials N2 - The OECD test guidelines (TGs) for testing chemicals have been widely used for regulatory purposes all over the world since the establishment of the Mutual Acceptance of Data (MAD) principle in 1984. This MAD principle ensures that, if a chemical is tested under the Good Laboratory Practice (GLP) conditions accordingly to an OECD TG, the data should be accepted in all OECD countries. The TGs have been developed, harmonized, internationally validated (round robin tests) and adopted by OECD countries to be used for the physical-chemical characterisation, fate estimation, and hazard identification for risk assessment of various chemicals. In addition to the TGs, OECD Guidance Documents (GDs) usually provide guidance on how to use TGs and how to interpret the results. These GDs do not have to be fully experimentally validated, and hence they are not under MAD, but they are based on relevant published scientific research. But are the existing TGs and the related GDs applicable and adequate for the regulatory testing of nanomaterials? In general, for nanomaterials it is accepted that most of the "endpoints" or more precisely measurement variables are applicable. However, for some endpoints new or amended TGs are needed. In addition, several GDs are needed to give more precise advice on the test performance in order to gain regulatory relevant data on nanomaterials. PB - Physikalisch-Technische Bundesanstalt CY - Braunschweig und Berlin T2 - NanoWorkshop 2018: Workshop on Reference Nanomaterials CY - Berlin, Germany DA - 14.05.2018 KW - OECD KW - Nano KW - Guideline KW - Nanomaterials KW - Prüfrichtlinie PY - 2019 UR - https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/49515 AN - OPUS4-49515 SN - 978-3-95606-440-1 SN - 0179-0609 VL - F-61 SP - 279 EP - 279 AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany