TY - GEN A1 - He, Shulin T1 - Differentiation of immune response with castes in termites N2 - Effective immunity is essential for maintaining insect society integrity but the mechanisms that connect immunity at the level of the individual to the level of society are poorly understood. Here, we begin to resolve this issue by addressing the interaction between individual immunity and caste identity in the termite Neotermes castaneus. We characterize the transcriptomic responses of different castes to a general immune challenge by sequencing mRNAs from false workers, soldiers and reproductive following injection with a cocktail of heat-killed pathogens. We found many more genes to be differentially regulated in reproductives (1420 and 398 genes down- and upregulated respectively) than soldiers (90 and 108 genes) or false workers (135 and 71 genes). We go on to conduct a quantitative analysis of the specific changes to immune regulation across the castes following pathogen exposure, before discussing the implications of these findings for our understanding of the evolution of immunity in eusocial termites. T2 - Ecological Immunology Workshop 2017 CY - Blossin, Brandenburg, Germany DA - 28.08.2017 KW - Termite KW - Immunity KW - Caste PY - 2017 UR - https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/44251 AN - OPUS4-44251 AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany