TY - RPRT A1 - Wohlleben, W. A1 - Mielke, Johannes A1 - Hodoroaba, Vasile-Dan A1 - Zimathies, Annett A1 - Bianchin, A. A1 - Lecloux, A. A1 - Roebben, G. A1 - Rauscher, H. A1 - Gibson, N. T1 - Development of an integrated approach based on validated and standardized methods to support the implementation of the EC recommendation for a definition of nanomaterial N2 - The VSSA approach has the important advantage over classifying, imaging and counting techniques that it does not involve dispersion protocols. Further, the BET technique as the basis for VSSA determination it is in widespread use, generates low costs and is specified for many commercial materials. Finally, the same equipment allows for a deeper analysis by full isotherm evaluation. The present deliverable assesses all NanoDefine powders, supplemented by further real-world materials (in total 26 powders), and quantitatively compares the relationship between the median size (by Electron Microscopy – considered as benchmark for the EC nanomaterial definition) vs. the size derived from VSSA. The VSSA method mitigates the challenges of EM to assess the thickness of platelets, but worked as well on fibbers and particles of irregular shapes. A screening strategy is proposed. If applied to the further data from real-world materials as validation set, this screening does achieve a correct classification, leaving only borderline materials for tier 2 assessment. PB - The NanoDefine Consortium CY - Wageningen, The Netherlands KW - Nanomaterial KW - Classification KW - Regulation KW - VSSA KW - Size measurement KW - Particle size PY - 2017 UR - https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/39893 AN - OPUS4-39893 UR - https://nbn-resolving.org/urn:nbn:de:kobv:b43-398938 SP - 1 EP - 26 AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany