TY - JOUR A1 - Weidner, Steffen A1 - Falkenhagen, Jana T1 - LC-MALDI-TOF imaging MS: a new approach in combining chromatography and mass spectrometry of copolymers T2 - Analytical chemistry N2 - A new approach that utilizes MALDI-TOF imaging mass spectrometry as a new detector for polymer chromatography is presented. For the first time, the individual retention behavior of single structural units of polyethylene oxide (PEO)/polypropylene oxide (PPO) copolymers and changes of the copolymer composition could be monitored. Composition specific calibration curves could be easily obtained by displaying the copolymer ion intensity data. This approach provides completely new insights in the chromatographic principle of copolymer separation and could be used to easily modify and adapt conditions for separation. In combination with electrospray deposition, homogeneous sample/matrix traces of surprisingly high spatial resolution could be obtained. PB - American Chemical Society CY - Washington, DC KW - MALDI KW - Massenspektrometrie KW - Imaging KW - Chromatographie KW - Polymere PY - 2011 UR - https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/24974 AN - OPUS4-24974 SN - 0003-2700 SN - 1520-6882 VL - 83 IS - 23 SP - 9153 EP - 9158 AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany