TY - JOUR A1 - Gorelik, T.E. A1 - Sarfraz, Adnan A1 - Kolb, U. A1 - Emmerling, Franziska A1 - Rademann, Klaus T1 - Detecting crystalline nonequilibrium phases on the nanometer scale JF - Crystal growth & design N2 - The use of Automated electron Diffraction Tomography (ADT) is presented as a novel approach for crystallization studies at the nanometer scale for nonequilibrium phases. Here, ADT was applied to elucidate the structural identity of the recently reported hexagonal morphology of caffeine crystals, which grow only on specific surfaces. Caffeine was crystallized from solution on a specially treated TEM carbon grid. The analysis of ADT data revealed that the lattice parameters of these hexagons match those of the high temperature α-form of caffeine. Furthermore, it was observed that in this hexagonal morphology, the α-form remained stable for a prolonged period of time. The stabilization of hexagons can be interpreted in terms of enhanced interactions with the supporting surfaces. KW - Electron diffraction KW - Polymorphism caffeine KW - ADT PY - 2012 DO - https://doi.org/10.1021/cg300377j SN - 1528-7483 VL - 12 IS - 6 SP - 3239 EP - 3242 PB - American Chemical Society CY - Washington, DC, USA AN - OPUS4-26285 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -