TY - CONF A1 - Rack, A. A1 - Stiller, M. A1 - Nelson, K. A1 - Knabe, C. A1 - Rack, T. A1 - Zabler, S. A1 - Dalügge, O. A1 - Riesemeier, Heinrich A1 - Cecilia, A. A1 - Goebbels, Jürgen T1 - Ex vivo and in vitro synchrotron-based micro-imaging of biocompatible materials applied in dental surgery T2 - Developments in X-ray tomography VII (Proceedings of SPIE) N2 - Biocompatible materials such as porous bioactive calcium phosphate ceramics or titanium are regularly applied in dental surgery: ceramics are used to support the local bone regeneration in a given defect, afterwards titanium implants replace lost teeth. The current gold standard for bone reconstruction in implant dentistry is the use of autogenous bone grafts. But the concept of guided bone regeneration (GBR) has become a predictable and well documented surgical approach using biomaterials (bioactive calcium phosphate ceramics) which qualify as bone substitutes for this kind of application as well. We applied high resolution synchrotron microtomography and subsequent 3d image analysis in order to investigate bone formation and degradation of the bone substitute material in a three-dimensional manner, extending the knowledge beyond the limits of classical histology. Following the bone regeneration, titanium-based implants to replace lost teeth call for high mechanical precision, especially when two-piece concepts are used in order to guaranty leak tightness. Here, synchrotron-based radiography in comparison with classical laboratory radiography yields high spatial resolution in combination with high contrast even when exploiting micro-sized features in these kind of highly attenuating objects. Therefore, we could study micro-gap formation at interfaces in two-piece dental implants with the specimen under different mechanical load. We could prove the existence of micro-gaps for implants with conical connections as well as to study the micromechanical behavior of the mating zone of conical implants during loading. The micro-gap is a potential issue of failure, i. e. bacterial leakage which can induce an inflammatory process. T2 - SPIE Conference 7804 - Developments in X-ray tomography VII CY - San Diego, CA, USA DA - 2010-08-02 KW - Microtomography KW - Synchrotron radiation KW - Radiography KW - Dental implants KW - Bioceramics KW - Implant-abutment interface PY - 2010 DO - https://doi.org/10.1117/12.858435 SN - 0277-786X N1 - Serientitel: SPIE proceedings series – Series title: SPIE proceedings series VL - 7804 SP - 78040E-1 - 78040E-8 AN - OPUS4-22731 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -