TY - JOUR A1 - Roos, P.H. A1 - Jakubowski, Norbert T1 - Cytochromes - fascinating molecular machines JF - Metallomics N2 - A huge number of functions and reactions can be performed by proteins merely based on their amino acids and their spatial arrangement which results in a specific geometric and electronic environment. The diversity and efficiency of functions, however, can be increased by protein-bound cofactors which fulfil their task in close interaction with the surrounding amino acid side chains. Among these cofactors, metals play an important role. They can be bound to proteins directly via specific amino acids such as cysteine and histidine, for example in zinc finger proteins or in iron sulfur cluster proteins. Another possibility is their integration into the 3D-structure of a protein via a prosthetic group. Porphyrine or porphyrine-like molecules with copper or iron as central bound metal ions constitute important structures in this respect. PY - 2011 DO - https://doi.org/10.1039/c1mt90012a SN - 1756-5901 SN - 1756-591X VL - 3 SP - 316 EP - 318 PB - RSC Publ. CY - Cambridge AN - OPUS4-23830 LA - eng AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany ER -