TY - JOUR A1 - Maenz, S. A1 - Brinkmann, O. A1 - Kunisch, E. A1 - Horbert, V. A1 - Gunella, F. A1 - Bischoff, S. A1 - Schubert, H. A1 - Sachse, A. A1 - Xin, L. A1 - Günster, Jens A1 - Illerhaus, Bernhard A1 - Jandt, K. D. A1 - Bossert, J. A1 - Kinne, R. W. A1 - Bungartz, M. T1 - Enhanced bone formation in sheep vertebral bodies after minimally invasive treatment with a novel, PLGA fiber-reinforced brushite cement. T2 - The Spine Journal N2 - Injectable, brushite-forming calcium phosphate cements (CPC) show potential for bone replacement, but they exhibit low mechanical strength. This study tested a CPC reinforced with poly(l-lactide-co-glycolide) acid (PLGA) fibers in a minimally invasive, sheep lumbar vertebroplasty model. The study aimed to test the in vivo biocompatibility and osteogenic potential of a PLGA fiber-reinforced, brushite-forming CPC in a sheep large animal model. PB - Elsevier Science direct KW - µCT KW - Vertebral KW - PLGA cement PY - 2017 UR - https://opus4.kobv.de/opus4-bam/frontdoor/index/index/docId/40462 AN - OPUS4-40462 UR - http://www.sciencedirect.com/science/article/pii/S152994301631066X SN - 1529-9430 SN - 1878-1632 VL - 17 IS - 5 SP - 709 EP - 719 AD - Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin, Germany