Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter
Author: | Dimitrios Vagiannis, Yu Zhang, Youssif Budagaga, Eva Novotna, Adam Skarka, Sarah KammererORCiD, Jan-Heiner KüpperGND, Jakub Hofman |
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DOI: | https://doi.org/10.1016/j.taap.2021.115823 |
ISSN: | 0041-008X |
Title of the source (English): | Toxicology and Applied Pharmacology |
Document Type: | Scientific journal article peer-reviewed |
Language: | English |
Year of publication: | 2022 |
Volume/Year: | Vol. 434 |
Number of pages: | 13 |
Article number: | 115823 |
Faculty/Chair: | Fakultät 2 Umwelt und Naturwissenschaften / FG Molekulare Zellbiologie |