Metabolic activity testing can underestimate acute drug cytotoxicity as revealed by HepG2 cell clones overexpressing cytochrome P450 2C19 and 3A4
Author: | Susanne Steinbrecht, Rosalie König, Kai-Uwe Schmidtke, Natalie Herzog, Katrin Scheibner, Anne Krüger-Genge, Friedrich Jung, Sarah KammererORCiD, Jan-Heiner KüpperGND |
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DOI: | https://doi.org/10.1016/j.tox.2018.11.008 |
ISSN: | 0300-483X |
Title of the source (English): | Toxicology |
Document Type: | Scientific journal article peer-reviewed |
Language: | English |
Year of publication: | 2018 |
Volume/Year: | 412 |
First Page: | 37 |
Last Page: | 47 |
Faculty/Chair: | Fakultät 2 Umwelt und Naturwissenschaften / FG Enzymtechnologie |
Fakultät 2 Umwelt und Naturwissenschaften / FG Molekulare Zellbiologie |