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COVID-19 among Healthcare Workers: A Prospective Serological-Epidemiological Cohort Study in a Standard Care Hospital in Rural Germany

  • Healthcare workers (HCW) play a vital role in the SARS-CoV-2 pandemic control. The aim of this study was to assess the prevalence of SARS-CoV-2 antibodies and the risk of COVID-19 infections in a cohort of HCW from four different risk groups (from intensive care unit to administration) of a hospital of a primary care level in rural Germany. The outcomes were monthly measures of antibody seroprevalence over a period of 6 months. Overall, a seroprevalence of 13.41% was determined, with significantly higher prevalence rates among HCW working in areas with more frequent contact to confirmed or suspected cases (30.30%, p = 0.003). The group specific differences in the risk of infection from COVID-19 were detected, as HCW groups with frequent exposure seemed to have an increased risk (RR = 3.18, p = 0.02; CI95 1.09–9.24). The findings contribute to the epidemiological understanding of the virus spread in an unvaccinated population group, which is highly relevant for the pandemic management.

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Author: Stephanie HoffmannORCiD, Juliane Schiebel, Frank Hufert, Heinz-Detlef Gremmels, Jacob SpallekORCiDGND
URL:https://www.mdpi.com/1660-4601/18/20/10999
DOI:https://doi.org/10.3390/ijerph182010999
ISSN:1660-4601
Title of the source (English):International Journal of Environmental Research and Public Health
Document Type:Scientific journal article peer-reviewed
Language:English
Year of publication:2021
Tag:COVID-19; SARS-CoV-2; antibody; healthcare; immunity; pandemic; seroprevalence; staff
Volume/Year:18
Issue number:20
Number of pages:8
Article number:10999
Faculty/Chair:Fakultät 4 Humanwissenschaften (bis 2023 Soziale Arbeit, Gesundheit und Musik) / FG Gesundheitswissenschaften
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