COVID-19 and the endothelium
- There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a generalized inflammatory state and complement elements may together contribute to the overall pro-coagulative state described in COVID-19 patients leading to venular as well as to arteriolar occlusions.
Author: | Friedrich Jung, Anne Krüger-Genge, Ralf-Peter Franke, Frank Hufert, Jan-Heiner KüpperGND |
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URL: | https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch209007 |
DOI: | https://doi.org/10.3233/CH-209007 |
ISSN: | 1875-8622 |
ISSN: | 1386-0291 |
Title of the source (English): | Clinical Hemorheology and Microcirculation |
Document Type: | Scientific journal article peer-reviewed |
Language: | English |
Year of publication: | 2020 |
Tag: | COVID-19; endocytosis; endothelial cell dysfunction; endotheliitis |
Volume/Year: | 75 |
Issue number: | 1 |
First Page: | 7 |
Last Page: | 11 |
Faculty/Chair: | Fakultät 2 Umwelt und Naturwissenschaften / FG Molekulare Zellbiologie |