TY - GEN A1 - Spitzer, Stefan G. A1 - Richter, P. A1 - Knaut, M. A1 - Schüler, S. T1 - Treatment of Atrial Fibrillation in Open Heart Surgery. The Potential Role of Microwave Energy T2 - The Thoracic and Cardiovascular Surgeon Y1 - 1999 SN - 0946-4778 VL - 47 IS - Supplement 3 SP - 374 EP - 378 ER - TY - GEN A1 - Karolyi, L. A1 - Ebert, H. A1 - Otto, T. A1 - Hansen, C. A1 - Spitzer, Stefan G. T1 - First Clinical Experiences with a Novel Non-Contact Mapping System T2 - Progress in Biomedical Research Y1 - 1999 SN - 1431-8202 VL - 4 IS - 4 SP - 427 EP - 430 ER - TY - GEN A1 - Spitzer, Stefan G. T1 - Pacing and ICD therapy in Germany (West and East) Before and After Reunification in 1989 T2 - Pace : Pacing and clinical electrophysiology Y1 - 1999 SN - 0147-8389 SN - 1540-8159 VL - 22 IS - 8 SP - 1248 EP - 1252 ER - TY - GEN A1 - Glasauer, Stefan A1 - Shi, Z. T1 - Another dead salmon? The measurement flaw of serial dependence in human perception T2 - Abstract for SfN Global Connectome Y1 - 2020 UR - https://www.sfn.org/-/media/SfN/Documents/NEW-SfN/Meetings/SfN-Global-Connectome/SFN21_Connectome_Abstracts_PDFs.pdf SP - 1891 EP - 11892 ER - TY - GEN A1 - Yudice, Joshua A1 - Bayer, Johanna A1 - Bockisch, Christopher A1 - Glasauer, Stefan T1 - Inter-subject variability of visual-vestibular sensory fusion during angular rotation T2 - Bernstein Conference 2020 Y1 - 2020 U6 - https://doi.org/10.12751/nncn.bc2020.0250 ER - TY - GEN A1 - Yudice, Joshua A1 - Glasauer, Stefan T1 - Navigational frame of reference during idiothetic path integration in humans T2 - INAV 2020 Y1 - 2020 UR - https://inavsymposium.com/wp-content/uploads/2020/10/Data_Blitz_Booklet_2020.pdf VL - 2020 SP - 41 ER - TY - GEN A1 - Striteska, Maja A1 - Chovanec, Martin A1 - Steinmetzer, Tobias A1 - Chrobok, Viktor A1 - Profant, Oliver A1 - Schneider, Erich A1 - Kremlacek, Jan A1 - Valis, Martin T1 - Binocular video head impulse test: Normative data study T2 - Frontiers in Neurology N2 - Introduction The video head impulse test (vHIT) evaluates the vestibulo-ocular reflex (VOR). It’s usually recorded from only one eye. Newer vHIT devices allow a binocular quantification of the VOR. Purpose (Aim) To investigate the advantages of simultaneously recorded binocular vHIT (bvHIT) to detect the differences between the VOR gains of the adducting and the abducting eye, to define the most precise VOR measure, and to assess gaze dys/conjugacy. We aimed to establish normative values for bvHIT adducting/abducting eye VOR gains and to introduce the VOR dysconjugacy ratio (vorDR) between adducting and abducting eyes for bvHIT. Methods We enrolled 44 healthy adult participants in a cross-sectional, prospective study using a repeated-measures design to assess test–retest reliability. A binocular EyeSeeCam Sci 2 device was used to simultaneously record bvHIT from both eyes during impulsive head stimulation in the horizontal plane. Results Pooled bvHIT retest gains of the adducting eye significantly exceeded those of the abducting eye (mean (SD): 1.08 (SD = 0.06), 0.95 (SD = 0.06), respectively). Both adduction and abduction gains showed similar variability, suggesting comparable precision and therefore equal suitability for VOR asymmetry assessment. The pooled vorDR here introduced to bvHIT was 1.13 (SD = 0.05). The test–retest repeatability coefficient was 0.06. Conclusion Our study provides normative values reflecting the conjugacy of eye movement responses to horizontal bvHIT in healthy participants. The results were similar to a previous study using the gold-standard scleral search coil, which also reported greater VOR gains in the adducting than in the abducting eye. In analogy to the analysis of saccade conjugacy, we propose the use of a novel bvHIT dysconjugacy ratio to assess dys/conjugacy of VOR-induced eye movements. In addition, to accurately assess VOR asymmetry, and to avoid directional gain preponderance between adduction and abduction VOR-induced eye movements leading to monocular vHIT bias, we recommend using a binocular ductional VOR asymmetry index that compares the VOR gains of only the abduction or only the adduction movements of both eyes. KW - binocular video head impulse test KW - conjugate gaze KW - adduction KW - abduction KW - ductional VOR asymmetry index KW - dysconjugacy ratio KW - monocular VOR asymmetry index KW - vestibuloocular reflex Y1 - 2023 U6 - https://doi.org/10.3389/fneur.2023.1153102 SN - 1664-2295 VL - 14 ER - TY - GEN A1 - Ramaioli, Cecilia A1 - Steinmetzer, Tobias A1 - Brietzke, Adrian A1 - Meyer, Paul A1 - Pham Xuan, Rebecca A1 - Schneider, Erich A1 - Gorges, Martin T1 - Assessment of vestibulo-ocular reflex and its adaptation during stop-and-go car rides in motion sickness susceptible passengers T2 - Experimental Brain Research N2 - Motion sickness is a physiological condition that negatively impacts a person's comfort and will be an emerging condition in autonomous vehicles without proper countermeasures. The vestibular system plays a key role in the origin of motion sickness. Understanding the susceptibility and (mal) adaptive mechanisms of the highly integrated vestibular system is a prerequisite for the development of countermeasures. We hypothesize a differential association between motion sickness and vestibular function in healthy individuals with and without susceptibility for motion sickness. We quantified vestibular function by measuring the high-frequency vestibulo-ocular reflex (VOR) using video head impulse testing (vHIT) in 17 healthy volunteers before and after a 11 min motion sickness-inducing naturalistic stop-and-go car ride on a test track (Dekra Test Oval, Klettwitz, Germany). The cohort was classified as motion sickness susceptible (n = 11) and non-susceptible (n = 6). Six (out of 11) susceptible participants developed nausea symptoms, while a total of nine participants were free of these symptoms. The VOR gain (1) did not differ significantly between participant groups with (n = 8) and without motion sickness symptoms (n = 9), (2) did not differ significantly in the factor time before and after the car ride, and showed no interaction between symptom groups and time, as indicated by a repeated measures ANOVA (F(1,15) = 2.19, p = 0.16. Bayesian inference confirmed that there was “anecdotal evidence” for equality of gain rather than difference across groups and time (BF10 < 0.77). Our results suggest that individual differences in VOR measures or adaptation to motion sickness provocative stimuli during naturalistic stop-and-go driving cannot predict motion sickness susceptibility or the likelihood of developing motion sickness. KW - Video head impulse test KW - Vestibulo-ocular reflex KW - Adaptation KW - Motion sickness KW - Stop-and-go car ride Y1 - 2023 U6 - https://doi.org/10.1007/s00221-023-06619-4 SN - 1432-1106 SN - 0014-4819 VL - 241 IS - 6 SP - 1523 EP - 1531 ER -